{ "uniprot_canonical_ac": "A0A1D5PXT4-1", "uniprot_ac": "A0A1D5PXT4", "uniprot_id": "A0A1D5PXT4_CHICK", "mass": { "chemical_mass": 56791.0, "monoisotopic_mass": 56791.0 }, "refseq": { "ac": "XP_004949290", "name": "dual specificity protein phosphatase CDC14B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949290" }, "gene_names": [ { "name": "CDC14B", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4", "id": "A0A1D5PXT4" }, { "name": "Cdc14B", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4", "id": "A0A1D5PXT4" }, { "name": "CDC14B", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949290", "id": "XP_004949290" }, { "name": "CDC14B", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4", "id": "A0A1D5PXT4" } ], "protein_names": [ { "name": "protein-tyrosine-phosphatase", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXT4/entry#names_and_taxonomy", "id": "A0A1D5PXT4" }, { "name": "3.1.3.48", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXT4/entry#names_and_taxonomy", "id": "A0A1D5PXT4" }, { "name": "dual specificity protein phosphatase CDC14B isoform X1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949290", "id": "XP_004949290" } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949290" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC14B", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4", "locus": { "chromosome": "Z", "start_pos": 42822554, "end_pos": 42872165, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010844", "url": "https://www.ensembl.org/id/ENSGALG00010010844" } ] } } ], "crossref": [ { "id": "A0A1D5PXT4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PXT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012627", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012627", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14499", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14499", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17657", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17657", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427473", "url": "https://www.ncbi.nlm.nih.gov/gene/427473", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427473", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427473", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLVEKQT", "url": "https://omabrowser.org/oma/group/FLVEKQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PXT4", "url": "https://www.orthodb.org/?gene=A0A1D5PXT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23339:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23339:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF14671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14671", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-5687128", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5687128", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "XP_004949290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949290", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PXT4-1", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6P9", "url": "https://www.uniprot.org/uniprot/A0A8V0Y6P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6P9-1", "url": "https://www.uniprot.org/uniprot/A0A8V0Y6P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF75", "url": "https://www.uniprot.org/uniprot/A0A8V0YF75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF75-1", "url": "https://www.uniprot.org/uniprot/A0A8V0YF75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D5K9Y4", "url": "https://www.uniprot.org/uniprot/D5K9Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D5K9Y4-1", "url": "https://www.uniprot.org/uniprot/D5K9Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRKSWAEARRRASPPPALKRTRSTASRTAEEQDEERKQTPSTVGPETCVQIADRLYFAILCQKPKSGAADTHYFCIDSELVYENFYGDFGPLNLAMVYKYCCKLNKKLKSFSLVKKKIVHYTGFDRKKQANAAFLIGSYAIIYLKESPEDVYKLVLAGSVSYLPFRDASFGTCSFHLTLLDCFHAINKALQYGFLDFDEFDVNEYEHYERAENGDFNWIIPNKFIAFSGPHSRSKIENGYPHHAPEAYFPYFRKHKVTTIIRLNKKMYDARRFTDAGFEHFDLFFADGSIPNDTIVKAFLNICENAEGVVAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWIRINRPGSVIGPQQHFLLEKQPELWTEGDLFHAKLRRNCKVGVTRILSGVGHISINGIRNRRTIQNDTELYSDEDEIDCITQGDKLRALKSKRQAKSTTASPLKVILQSSVQKNKTSEPSISDSTNITKRTTRSAARNKSIKSSQSTTRTRTVLR", "length": 499, "header": "tr|A0A1D5PXT4-1|A0A1D5PXT4_CHICK Isoform 1 of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=CDC14B PE=3 SV=1 CANONICAL=A0A1D5PXT4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PXT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXT4/entry#A0A1D5PXT4-1", "sequence": { "sequence": "MKRKSWAEARRRASPPPALKRTRSTASRTAEEQDEERKQTPSTVGPETCVQIADRLYFAILCQKPKSGAADTHYFCIDSELVYENFYGDFGPLNLAMVYKYCCKLNKKLKSFSLVKKKIVHYTGFDRKKQANAAFLIGSYAIIYLKESPEDVYKLVLAGSVSYLPFRDASFGTCSFHLTLLDCFHAINKALQYGFLDFDEFDVNEYEHYERAENGDFNWIIPNKFIAFSGPHSRSKIENGYPHHAPEAYFPYFRKHKVTTIIRLNKKMYDARRFTDAGFEHFDLFFADGSIPNDTIVKAFLNICENAEGVVAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWIRINRPGSVIGPQQHFLLEKQPELWTEGDLFHAKLRRNCKVGVTRILSGVGHISINGIRNRRTIQNDTELYSDEDEIDCITQGDKLRALKSKRQAKSTTASPLKVILQSSVQKNKTSEPSISDSTNITKRTTRSAARNKSIKSSQSTTRTRTVLR", "length": 499, "header": "tr|A0A1D5PXT4-1|A0A1D5PXT4_CHICK Isoform 1 of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=CDC14B PE=3 SV=1 CANONICAL=A0A1D5PXT4-1" }, "locus": { "chromosome": "Z", "start_pos": 42872008, "end_pos": 42826345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025974.1", "url": "https://www.ensembl.org/id/ENSGALT00010025974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014635.1", "url": "https://www.ensembl.org/id/ENSGALP00010014635.1" } ] } }, { "isoform_ac": "A0A8V0Y6P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXT4/entry#A0A8V0Y6P9-1", "sequence": { "sequence": "MKRKSWAEARRRASPPPALKRTRSTASRTAEEQDEERKQTPSTVGPETCVQIADRLYFAILCQKPKSGAADTHYFCIDSELVYENFYGDFGPLNLAMVYKYCCKLNKKLKSFSLVKKKIVHYTGFDRKKQANAAFLIGSYAIIYLKESPEDVYKLVLAGSVSYLPFRDASFGTCSFHLTLLDCFHAINKALQYGFLDFDEFDVNEYEHYERAENGDFNWIIPNKFIAFSGPHSRSKIENGYPHHAPEAYFPYFRKHKVTTIIRLNKKMYDARRFTDAGFEHFDLFFADGSIPNDTIVKAFLNICENAEGVVAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWIRINRPGSVIGPQQHFLLEKQPELWTEGDLFHAKLRRNCKVGVTRILSGVGHISINGIRNRRTIQNDTELYSDEDEIDCITQGDKLRALKSKRQAKSTTASPLKVILQSSVQKNKTSEPSISDSTNITKRTTRSAARNKSIKRDICS", "length": 491, "header": "tr|A0A8V0Y6P9-1|A0A8V0Y6P9_CHICK Computationally mapped isoform of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=CDC14B PE=3 SV=1 CANONICAL=A0A1D5PXT4-1" }, "locus": { "chromosome": "Z", "start_pos": 42872008, "end_pos": 42829331, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025954.1", "url": "https://www.ensembl.org/id/ENSGALT00010025954.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014618.1", "url": "https://www.ensembl.org/id/ENSGALP00010014618.1" } ] } }, { "isoform_ac": "A0A8V0YF75-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXT4/entry#A0A8V0YF75-1", "sequence": { "sequence": "MKRKSWAEARRRASPPPALKRTRSTASRTAEEQDEERKQTPSTVGPETCVQIADRLYFAILCQKPKSGAADTHYFCIDSELVYENFYGDFGPLNLAMVYKYCCKLNKKLKSFSLVKKKIVHYTGFDRKKQANAAFLIGSYAIIYLKESPEDVYKLVLAGSVSYLPFRDASFGTCSFHLTLLDCFHAINKRAENGDFNWIIPNKFIAFSGPHSRSKIENGYPHHAPEAYFPYFRKHKVTTIIRLNKKMYDARRFTDAGFEHFDLFFADGSIPNDTIVKAFLNICENAEGVVAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWIRINRPGSVIGPQQHFLLEKQPELWTEGDLFHAKLRRNCKVGVTRILSGVGHISINGIRNRRTIQNDTELYSDEDEIDCITQGDKLRALKSKRQAKSTTASPLNSQSTTRTRTVLR", "length": 439, "header": "tr|A0A8V0YF75-1|A0A1D5PXT4_CHICK Computationally mapped isoform of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=CDC14B PE=3 SV=1 CANONICAL=A0A1D5PXT4-1" }, "locus": { "chromosome": "Z", "start_pos": 42872008, "end_pos": 42826345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025969.1", "url": "https://www.ensembl.org/id/ENSGALT00010025969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014630.1", "url": "https://www.ensembl.org/id/ENSGALP00010014630.1" } ] } }, { "isoform_ac": "D5K9Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXT4/entry#D5K9Y4-1", "sequence": { "sequence": "MKRKSWAEARRRASPPPALKRTRSTASRTAEEQDEERKQTPSTVGPETCVQIADRLYFAILCQKPKSGAADTHYFCIDSELVYENFYGDFGPLNLAMVYKYCCKLNKKLKSFSLVKKKIVHYTGFDRKKQANAAFLIGSYAIIYLKESPEDVYKLVLAGSVSYLPFRDASFGTCSFHLTLLDCFHAINKALQYGFLDFDEFDVNEYEHYERAENGDFNWIIPNKFIAFSGPHSRSKIENGYPHHAPEAYFPYFRKHKVTTIIRLNKKMYDARRFTDAGFEHFDLFFADGSIPNDTIVKAFLNICENAEGVVAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWIRINRPGSVIGPQQHFLLEKQPELWTEGDLFHAKLRRNCKVGVTRILSGVGHISINGIRNRRTIQNDTELYSDEDEIDCITQGDKLRALKSKRQAKSTTASPLNSQSTTRTRTVLR", "length": 460, "header": "tr|D5K9Y4-1|D5K9Y4_CHICK Computationally mapped isoform of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=Cdc14B PE=2 SV=1 CANONICAL=A0A1D5PXT4-1" }, "locus": { "chromosome": "Z", "start_pos": 42872008, "end_pos": 42826345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025981.1", "url": "https://www.ensembl.org/id/ENSGALT00010025981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014641.1", "url": "https://www.ensembl.org/id/ENSGALP00010014641.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair.", "journal": "J. Cell Biol.", "date": "2010", "authors": "Mocciaro A, Berdougo E, Zeng K, Black E, Vagnarelli P, Earnshaw W, Gillespie D, Jallepalli P, Schiebel E", "evidence": [ { "database": "UniProtKB", "id": "D5K9Y4", "url": "https://www.uniprot.org/uniprot/D5K9Y4" } ], "reference": [ { "type": "PubMed", "id": "20479464", "url": "https://glygen.org/publication/PubMed/20479464" } ] } ], "pathway": [ { "id": "gga:427473", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427473", "resource": "KEGG Pathway" }, { "id": "R-GGA-5687128", "name": "MAPK6/MAPK4 signaling", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5687128", "resource": "Reactome", "description": "MAPK6/MAPK4 signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "membrane-bounded organelle", "id": "GO:0043227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043227", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "intracellular non-membrane-bounded organelle", "id": "GO:0043232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043232", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "myosin phosphatase activity", "id": "GO:0017018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017018", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "regulation of exit from mitosis", "id": "GO:0007096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007096", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "positive regulation of cytokinesis", "id": "GO:0032467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032467", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PXT4", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XM28-1", "A0A1D5PI23-1", "A0A1D5PXT4-1", "A0A8V0ZW37-1", "F1P225-1", "P62207-1", "A0A8V1AB34-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "A0A8V0ZCV8-1", "A0A8V0XLK8-1", "A0A8V0XRD8-1", "Q9YHA0-1", "A0A8V0Y1D0-1", "A0A8V0YLA3-1", "A0A8V0ZFN2-1", "A0A8V0ZMX1-1", "A0A8V1A8D0-1", "A0A8V0ZQ53-1", "A0A8V0ZMU4-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "E1BRQ8-1", "E1BTX9-1", "A0A8V0ZJ28-1", "Q5ZIM8-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "R-GGA-5692749", "name": "CDC14A,B bind MAPK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXT4-1", "Q5F3W3-1", "A0A8V0ZW37-1" ], "evidence": [ { "id": "R-GGA-5692749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5692749" } ] }, { "id": "R-GGA-5692754", "name": "CDC14A,B dephosphorylate p-3S,T MAPK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXT4-1", "Q5F3W3-1", "A0A8V0ZW37-1" ], "evidence": [ { "id": "R-GGA-5692754", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5692754" } ] }, { "id": "R-GGA-5692764", "name": "MAPK6 binds CCND3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PXT4-1", "Q5F3W3-1", "A0A8V0ZW37-1" ], "evidence": [ { "id": "R-GGA-5692764", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5692764" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PXT4", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XM28", "gene_name": "DUSP22AL", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XM28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XM28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XM28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XM28" } ] } ] }, { "uniprot_ac": "A0A8V0XRD8", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XRD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XRD8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XRD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XRD8" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0YLA3", "gene_name": "PPM1H", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YLA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YLA3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YLA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YLA3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0ZCV8", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZCV8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZCV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1AB34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1AB34" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1BTX9", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E1BTX9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E1BTX9" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1P225" } ] } ] }, { "uniprot_ac": "P0C597", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C597" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C597" } ] } ] }, { "uniprot_ac": "P48463", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48463" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48463" } ] } ] }, { "uniprot_ac": "P62207", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62207" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIM8", "gene_name": "PPP3CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZIM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZIM8" } ] } ] }, { "uniprot_ac": "Q5ZJJ8", "gene_name": "UBLCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZJJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZJJ8" } ] } ] }, { "uniprot_ac": "Q5ZJQ7", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZJQ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZJQ7" } ] } ] }, { "uniprot_ac": "Q9PTJ6", "gene_name": "NFI1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PTJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PTJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9PTJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PTJ6" } ] } ] }, { "uniprot_ac": "Q9PW71", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PW71" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PW71" } ] } ] }, { "uniprot_ac": "Q9YHA0", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YHA0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YHA0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PXT4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 499, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PXT4-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.48" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 293, "end_pos": 295 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 482, "end_pos": 484 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }