The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI23-1", "Q5F335-1", "F1NCC5-1" ], "evidence": [ { "id": "R-GGA-203797", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-203797" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NXI7", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5NXI7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5NXI7" } ] } ] }, { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5P6Q1", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5P6Q1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5P6Q1" } ] } ] }, { "uniprot_ac": "A0A1D5PC43", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PC43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PC43" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PXT4", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PXT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PXT4" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X4H3", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0X4H3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0X4H3" } ] } ] }, { "uniprot_ac": "A0A8V0X7T6", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X7T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0X7T6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X7T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0X7T6" } ] } ] }, { "uniprot_ac": "A0A8V0XA98", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XA98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XA98" } ] } ] }, { "uniprot_ac": "A0A8V0XFP0", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XFP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XFP0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XFP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XFP0" } ] } ] }, { "uniprot_ac": "A0A8V0XI03", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XI03" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XI03" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XM28", "gene_name": "DUSP22AL", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XM28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XM28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XM28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XM28" } ] } ] }, { "uniprot_ac": "A0A8V0XRD8", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XRD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XRD8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XRD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XRD8" } ] } ] }, { "uniprot_ac": "A0A8V0XVI4", "gene_name": "LOC100858919", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XVI4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XVI4" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H9", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y3H9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y3H9" } ] } ] }, { "uniprot_ac": "A0A8V0Y719", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y719" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y719" } ] } ] }, { "uniprot_ac": "A0A8V0Y8L5", "gene_name": "PTPRQ", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y8L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y8L5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Y8L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Y8L5" } ] } ] }, { "uniprot_ac": "A0A8V0YAF3", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YAF3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YAF3" } ] } ] }, { "uniprot_ac": "A0A8V0YAP9", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YAP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YAP9" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YFC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YFC8" } ] } ] }, { "uniprot_ac": "A0A8V0YFZ7", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YFZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YFZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YGL5", "gene_name": "PTPRO", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YGL5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YGL5" } ] } ] }, { "uniprot_ac": "A0A8V0YHN7", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YHN7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YHN7" } ] } ] }, { "uniprot_ac": "A0A8V0YIN5", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YLA3", "gene_name": "PPM1H", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YLA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YLA3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YLA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YLA3" } ] } ] }, { "uniprot_ac": "A0A8V0YM55", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YM55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YM55" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YM55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YM55" } ] } ] }, { "uniprot_ac": "A0A8V0YVP7", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YVP7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YVP7" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0Z256", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z256" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0Z920", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z920" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0Z920" } ] } ] }, { "uniprot_ac": "A0A8V0ZCV8", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZCV8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZCV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZH43", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZH43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZH43" } ] } ] }, { "uniprot_ac": "A0A8V0ZIN0", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZIN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZIN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS3", "gene_name": "LOC419429", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZLS3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZLS3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZP13", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZP13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZP13" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZP13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZP13" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZU36", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZU36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZU36" } ] } ] }, { "uniprot_ac": "A0A8V0ZVC2", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZVC2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZVC2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVG8", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZVG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZVG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V1A4B8", "gene_name": "PTPRVP", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1A4B8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1A4B8" } ] } ] }, { "uniprot_ac": "A0A8V1A896", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1A896" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1A896" } ] } ] }, { "uniprot_ac": "A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB05", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1AB05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1AB05" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1AB34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1AB34" } ] } ] }, { "uniprot_ac": "A0A8V1ANF4", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1ANF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V1ANF4" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1BTX9", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E1BTX9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E1BTX9" } ] } ] }, { "uniprot_ac": "F1NAX3", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "H2O + sn-glycerol 3-phosphate = glycerol + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NAX3" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NAX3" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NVR5", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NVR5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NVR5" } ] } ] }, { "uniprot_ac": "F1NWE3", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NWE3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1NWE3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1P225" } ] } ] }, { "uniprot_ac": "O13016", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O13016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13016" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O13016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13016" } ] } ] }, { "uniprot_ac": "P0C597", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C597" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C597" } ] } ] }, { "uniprot_ac": "P48463", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48463" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P48463" } ] } ] }, { "uniprot_ac": "P62207", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "H2O + O-phospho-L-threonyl-[myosin light chain] = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62207" } ] } ] }, { "uniprot_ac": "Q5F335", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5F335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F335" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5F335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F335" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5F335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F335" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5F335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F335" } ] } ] }, { "uniprot_ac": "Q5F4B1", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "H2O + sn-glycerol 3-phosphate = glycerol + phosphate.", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F4B1" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F4B1" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5F4B1" } ] } ] }, { "uniprot_ac": "Q5ZIM8", "gene_name": "PPP3CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZIM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZIM8" } ] } ] }, { "uniprot_ac": "Q5ZIQ1", "gene_name": "PTP4A1", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZIQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZIQ1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5ZIQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZIQ1" } ] } ] }, { "uniprot_ac": "Q5ZIV0", "gene_name": "PPP6C", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZIV0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZIV0" } ] } ] }, { "uniprot_ac": "Q5ZJJ8", "gene_name": "UBLCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZJJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZJJ8" } ] } ] }, { "uniprot_ac": "Q5ZJQ7", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZJQ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZJQ7" } ] } ] }, { "uniprot_ac": "Q5ZKG5", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZKG5" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZKG5" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZKG5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5ZKG5" } ] } ] }, { "uniprot_ac": "Q6YI48", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6YI48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6YI48" } ] } ] }, { "uniprot_ac": "Q7T2L9", "gene_name": "MKP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7T2L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7T2L9" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q7T2L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7T2L9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q7T2L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7T2L9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7T2L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7T2L9" } ] } ] }, { "uniprot_ac": "Q90687", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q90687" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q90687" } ] } ] }, { "uniprot_ac": "Q98936", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q98936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q98936" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q98936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q98936" } ] } ] }, { "uniprot_ac": "Q9PTJ6", "gene_name": "NFI1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PTJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PTJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9PTJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PTJ6" } ] } ] }, { "uniprot_ac": "Q9PW71", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PW71" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9PW71" } ] } ] }, { "uniprot_ac": "Q9W6V5", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9W6V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W6V5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9W6V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9W6V5" } ] } ] }, { "uniprot_ac": "Q9YH98", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YH98" } ] } ] }, { "uniprot_ac": "Q9YH99", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YH99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YH99" } ] } ] }, { "uniprot_ac": "Q9YHA0", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YHA0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9YHA0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PI23-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 184, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PI23-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.16", "ec_name": "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16" }, { "id": "3.1.3.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.16" } ] }, { "ec_number": "3.1.3.48", "ec_name": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.48" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 }, { "start_pos": 90, "end_pos": 92 }, { "start_pos": 96, "end_pos": 98 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }