{
    "uniprot_canonical_ac": "A0A1D5PCI4-1",
    "uniprot_ac": "A0A1D5PCI4",
    "uniprot_id": "A0A1D5PCI4_CHICK",
    "mass": {
        "chemical_mass": 47545.0,
        "monoisotopic_mass": 47545.0
    },
    "refseq": {
        "ac": "XP_004945171",
        "name": "cAMP-dependent protein kinase type I-beta regulatory subunit isoform X1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945171"
    },
    "gene_names": [
        {
            "name": "PRKAR1B",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A1D5PCI4",
            "id": "A0A1D5PCI4"
        },
        {
            "name": "PRKAR1B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945171",
            "id": "XP_004945171"
        }
    ],
    "protein_names": [
        {
            "name": "Protein kinase cAMP-dependent type I regulatory subunit beta",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCI4/entry#names_and_taxonomy",
            "id": "A0A1D5PCI4"
        },
        {
            "name": "cAMP-dependent protein kinase type I-beta regulatory subunit isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945171",
            "id": "XP_004945171"
        }
    ],
    "function": [
        {
            "annotation": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "XP_004945171",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945171"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Gallus gallus",
            "taxid": 9031,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A1D5PCI4",
                    "url": "https://www.uniprot.org/uniprot/A0A1D5PCI4"
                }
            ],
            "common_name": "Chicken",
            "glygen_name": "Chicken",
            "reference_species": "Gallus gallus [9031]"
        }
    ],
    "gene": [
        {
            "name": "PRKAR1B",
            "url": "https://www.uniprot.org/uniprot/A0A1D5PCI4",
            "locus": {
                "chromosome": "14",
                "start_pos": 2039212,
                "end_pos": 2127746,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSGALG00010022184",
                        "url": "https://www.ensembl.org/id/ENSGALG00010022184"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "A0A1D5PCI4",
            "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PCI4",
            "database": "AlphaFoldDB",
            "categories": []
        },
        {
            "id": "ENSGALG00000003675",
            "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003675",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00038",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00038",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd12102",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12102",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "416446",
            "url": "https://www.ncbi.nlm.nih.gov/gene/416446",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000595",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000595",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003117",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003117",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR012198",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012198",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR014710",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018488",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018488",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018490",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR042818",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR042818",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR050503",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR050503",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "gga:416446",
            "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416446",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "QILAWQK",
            "url": "https://omabrowser.org/oma/group/QILAWQK/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A1D5PCI4",
            "url": "https://www.orthodb.org/?gene=A0A1D5PCI4",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11635",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11635",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11635:SF126",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11635:SF126",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00027",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00027",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF02197",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02197",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-GGA-163615",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163615",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-GGA-164378",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-164378",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-GGA-180024",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-180024",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-GGA-432040",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432040",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-GGA-442720",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442720",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-GGA-5610787",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-GGA-9634597",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9634597",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-GGA-983231",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_004945171",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945171",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A1D5PCI4",
            "url": "https://www.uniprot.org/uniprot/A0A1D5PCI4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A1D5PCI4-1",
            "url": "https://www.uniprot.org/uniprot/A0A1D5PCI4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0ZNX3",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZNX3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0ZNX3-1",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZNX3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MLRLRSPPPLFYKLFIAGTESPDSSTWLISATVCLLFTSLKMAAASSCSVEEDESLKGCELYVQKHNIQQILKECIVNLCIAKPDRPMKFLREHFEKLEKEECKQILARQKSSSQSDSHDDEISPPPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGEWVTSIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV",
        "length": 422,
        "header": "tr|A0A1D5PCI4-1|A0A1D5PCI4_CHICK Isoform 1 of Protein kinase cAMP-dependent type I regulatory subunit beta  OS=Gallus gallus OX=9031 GN=PRKAR1B PE=1 SV=1 CANONICAL=A0A1D5PCI4-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A1D5PCI4-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCI4/entry#A0A1D5PCI4-1",
            "sequence": {
                "sequence": "MLRLRSPPPLFYKLFIAGTESPDSSTWLISATVCLLFTSLKMAAASSCSVEEDESLKGCELYVQKHNIQQILKECIVNLCIAKPDRPMKFLREHFEKLEKEECKQILARQKSSSQSDSHDDEISPPPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGEWVTSIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV",
                "length": 422,
                "header": "tr|A0A1D5PCI4-1|A0A1D5PCI4_CHICK Isoform 1 of Protein kinase cAMP-dependent type I regulatory subunit beta  OS=Gallus gallus OX=9031 GN=PRKAR1B PE=1 SV=1 CANONICAL=A0A1D5PCI4-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 2127706,
                "end_pos": 2041255,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010053969.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010053969.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010032507.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010032507.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8V0ZNX3-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCI4/entry#A0A8V0ZNX3-1",
            "sequence": {
                "sequence": "MAAASSCSVEEDESLKGCELYVQKHNIQQILKECIVNLCIAKPDRPMKFLREHFEKLEKEECKQILARQKSSSQSDSHDDEISPPPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNPSSLFHPCVFAKTVYVNGEWVTSIGEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV",
                "length": 380,
                "header": "tr|A0A8V0ZNX3-1|A0A8V0ZNX3_CHICK Computationally mapped isoform of Protein kinase cAMP-dependent type I regulatory subunit beta  OS=Gallus gallus OX=9031 GN=PRKAR1B PE=1 SV=1 CANONICAL=A0A1D5PCI4-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 2126425,
                "end_pos": 2041255,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010053976.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010053976.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010032512.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010032512.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "gga:416446",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416446",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-GGA-163615",
            "name": "PKA activation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163615",
            "resource": "Reactome",
            "description": "PKA activation"
        },
        {
            "id": "R-GGA-164378",
            "name": "PKA activation in glucagon signalling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-164378",
            "resource": "Reactome",
            "description": "PKA activation in glucagon signalling"
        },
        {
            "id": "R-GGA-180024",
            "name": "DARPP-32 events",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-180024",
            "resource": "Reactome",
            "description": "DARPP-32 events"
        },
        {
            "id": "R-GGA-432040",
            "name": "Vasopressin regulates renal water homeostasis via Aquaporins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432040",
            "resource": "Reactome",
            "description": "Vasopressin regulates renal water homeostasis via Aquaporins"
        },
        {
            "id": "R-GGA-442720",
            "name": "CREB1 phosphorylation through the activation of Adenylate Cyclase",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442720",
            "resource": "Reactome",
            "description": "CREB1 phosphorylation through the activation of Adenylate Cyclase"
        },
        {
            "id": "R-GGA-5610787",
            "name": "Hedgehog 'off' state",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787",
            "resource": "Reactome",
            "description": "Hedgehog 'off' state"
        },
        {
            "id": "R-GGA-9634597",
            "name": "GPER1 signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9634597",
            "resource": "Reactome",
            "description": "GPER1 signaling"
        },
        {
            "id": "R-GGA-983231",
            "name": "Factors involved in megakaryocyte development and platelet production",
            "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231",
            "resource": "Reactome",
            "description": "Factors involved in megakaryocyte development and platelet production"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "F1RIY9-1",
            "protein_name": "Protein kinase cAMP-dependent type I regulatory subunit beta",
            "gene_name": "PRKAR1B",
            "tax_id": 9823,
            "organism": "Sus scrofa",
            "sequence": {
                "sequence": "MASPSPHQLEEDDSLRGCELYVQKHGVQQVLKDCIVQLCVSKPARPMKFLREHFEKLEKEENRQILAQQKSASQSDLYDEEVSPPLPNPVVKARHRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALARAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVVDQGEVDVYVNGEWVTSISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRRVYQEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV",
                "length": 381
            },
            "evidence": [
                {
                    "id": "A0A1D5PCI4",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PCI4/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Pig",
            "common_name": "Pig"
        },
        {
            "uniprot_canonical_ac": "P12849-1",
            "protein_name": "cAMP-dependent protein kinase type I-beta regulatory subunit",
            "gene_name": "Prkar1b",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MASPSCFHSEDEDSLKGCEMYVQKHGIQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENRQILARQKSNSQCDSHDEEISPTPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIGGETVIQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV",
                "length": 381
            },
            "evidence": [
                {
                    "id": "A0A1D5PCI4",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PCI4/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P31321-1",
            "protein_name": "cAMP-dependent protein kinase type I-beta regulatory subunit",
            "gene_name": "PRKAR1B",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV",
                "length": 381
            },
            "evidence": [
                {
                    "id": "A0A1D5PCI4",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PCI4/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P81377-1",
            "protein_name": "cAMP-dependent protein kinase type I-beta regulatory subunit",
            "gene_name": "Prkar1b",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MASPSCFHSEDEDSLKGCEMYVQKHGIQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENRQILARQKSNSQCDSHDEEISPTPPNPVVKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIDGETVIQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV",
                "length": 381
            },
            "evidence": [
                {
                    "id": "A0A1D5PCI4",
                    "url": "https://omabrowser.org/oma/group/A0A1D5PCI4/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Rat",
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 8,
                "go_terms": [
                    {
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