{ "uniprot_canonical_ac": "A0A1D5PBA3-1", "uniprot_ac": "A0A1D5PBA3", "uniprot_id": "A0A1D5PBA3_CHICK", "mass": { "chemical_mass": 67555.0, "monoisotopic_mass": 67555.0 }, "refseq": { "ac": "NP_990075", "name": "protein CBFA2T1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990075" }, "gene_names": [ { "name": "RUNX1T1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3", "id": "A0A1D5PBA3" }, { "name": "CBFA2T1; MTG8", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990075", "id": "NP_990075" }, { "name": "RUNX1T1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990075", "id": "NP_990075" } ], "protein_names": [ { "name": "MTG8/ETOb; expressed during postmitotic spinal neurons, most likely in motorneurons; protein CBFA2T1; runt-related transcription factor 1; translocated to, 1 (cyclin D-related)", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990075", "id": "NP_990075" }, { "name": "RUNX1 translocation partner 1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry#names_and_taxonomy", "id": "A0A1D5PBA3" }, { "name": "protein CBFA2T1 isoform 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990075", "id": "NP_990075" } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.262299.1, SRR13267660.10027.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000044.1. On or before Dec 10, 2021 this sequence version replaced XP_015138256.1, NP_990075.1. Transcript Variant: This variant (1) encodes the longest isoform (1).", "evidence": [ { "database": "RefSeq", "id": "NP_990075", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990075" } ] }, { "annotation": "Both wild type MTGs and chimeric AML1-MTG proteins display in vitro RNA-binding properties Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_990075", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990075" }, { "database": "PubMed", "id": "18950503", "url": "https://glygen.org/publication/PubMed/18950503" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RUNX1T1", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3", "locus": { "chromosome": "2", "start_pos": 124637531, "end_pos": 124747175, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011273", "url": "https://www.ensembl.org/id/ENSGALG00010011273" } ] } } ], "crossref": [ { "id": "A0A1D5PBA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PBA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033091", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033091", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395503", "url": "https://www.ncbi.nlm.nih.gov/gene/395503", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ESSVMEY", "url": "https://omabrowser.org/oma/group/ESSVMEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PBA3", "url": "https://www.orthodb.org/?gene=A0A1D5PBA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10379:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10379:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF07531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07531", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF08788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08788", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_990075", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990075", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P838", "url": "https://www.uniprot.org/uniprot/A0A1D5P838", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P838-1", "url": "https://www.uniprot.org/uniprot/A0A1D5P838-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PBA3-1", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3Z9", "url": "https://www.uniprot.org/uniprot/A0A8V0Y3Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3Z9-1", "url": "https://www.uniprot.org/uniprot/A0A8V0Y3Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8P7", "url": "https://www.uniprot.org/uniprot/A0A8V0Y8P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8P7-1", "url": "https://www.uniprot.org/uniprot/A0A8V0Y8P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Q9", "url": "https://www.uniprot.org/uniprot/A0A8V0Y8Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Q9-1", "url": "https://www.uniprot.org/uniprot/A0A8V0Y8Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA91", "url": "https://www.uniprot.org/uniprot/A0A8V0YA91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA91-1", "url": "https://www.uniprot.org/uniprot/A0A8V0YA91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF2", "url": "https://www.uniprot.org/uniprot/A0A8V0YCF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF2-1", "url": "https://www.uniprot.org/uniprot/A0A8V0YCF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH50", "url": "https://www.uniprot.org/uniprot/A0A8V0YH50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH50-1", "url": "https://www.uniprot.org/uniprot/A0A8V0YH50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISVKRNTWRALSLVIGDCRKKGNLEFCQDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 604, "header": "tr|A0A1D5PBA3-1|A0A1D5PBA3_CHICK Isoform 1 of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5PBA3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P838-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry#A0A1D5P838-1", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 577, "header": "tr|A0A1D5P838-1|A0A1D5P838_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5PBA3-1" }, "locus": { "chromosome": "2", "start_pos": 124713461, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026935.1", "url": "https://www.ensembl.org/id/ENSGALT00010026935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015340.1", "url": "https://www.ensembl.org/id/ENSGALP00010015340.1" } ] } }, { "isoform_ac": "A0A1D5PBA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry#A0A1D5PBA3-1", "sequence": { "sequence": "MISVKRNTWRALSLVIGDCRKKGNLEFCQDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 604, "header": "tr|A0A1D5PBA3-1|A0A1D5PBA3_CHICK Isoform 1 of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5PBA3-1" }, "locus": { "chromosome": "2", "start_pos": 124728318, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026947.1", "url": "https://www.ensembl.org/id/ENSGALT00010026947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015347.1", "url": "https://www.ensembl.org/id/ENSGALP00010015347.1" } ] } }, { "isoform_ac": "A0A8V0Y3Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry#A0A8V0Y3Z9-1", "sequence": { "sequence": "MISVKRNTWRALSLVIGDCRKKGNLEFCQVTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 558, "header": "tr|A0A8V0Y3Z9-1|A0A8V0Y3Z9_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5PBA3-1" }, "locus": { "chromosome": "2", "start_pos": 124728318, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026945.1", "url": "https://www.ensembl.org/id/ENSGALT00010026945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015346.1", "url": "https://www.ensembl.org/id/ENSGALP00010015346.1" } ] } }, { "isoform_ac": "A0A8V0Y8P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry#A0A8V0Y8P7-1", "sequence": { "sequence": "LPKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 573, "header": "tr|A0A8V0Y8P7-1|A0A1D5PBA3_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5PBA3-1" }, "locus": { "chromosome": "2", "start_pos": 124687278, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026922.1", "url": "https://www.ensembl.org/id/ENSGALT00010026922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015335.1", "url": "https://www.ensembl.org/id/ENSGALP00010015335.1" } ] } }, { "isoform_ac": "A0A8V0Y8Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry#A0A8V0Y8Q9-1", "sequence": { "sequence": "VTDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 577, "header": "tr|A0A8V0Y8Q9-1|A0A8V0Y8Q9_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5PBA3-1" }, "locus": { "chromosome": "2", "start_pos": 124687202, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026957.1", "url": "https://www.ensembl.org/id/ENSGALT00010026957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015350.1", "url": "https://www.ensembl.org/id/ENSGALP00010015350.1" } ] } }, { "isoform_ac": "A0A8V0YA91-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry#A0A8V0YA91-1", "sequence": { "sequence": "MVGISGPLQLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 538, "header": "tr|A0A8V0YA91-1|A0A8V0YA91_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5PBA3-1" }, "locus": { "chromosome": "2", "start_pos": 124747020, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026955.1", "url": "https://www.ensembl.org/id/ENSGALT00010026955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015348.1", "url": "https://www.ensembl.org/id/ENSGALP00010015348.1" } ] } }, { "isoform_ac": "A0A8V0YCF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry#A0A8V0YCF2-1", "sequence": { "sequence": "MPVTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 531, "header": "tr|A0A8V0YCF2-1|A0A1D5PBA3_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5PBA3-1" }, "locus": { "chromosome": "2", "start_pos": 124713461, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026929.1", "url": "https://www.ensembl.org/id/ENSGALT00010026929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015339.1", "url": "https://www.ensembl.org/id/ENSGALP00010015339.1" } ] } }, { "isoform_ac": "A0A8V0YH50-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBA3/entry#A0A8V0YH50-1", "sequence": { "sequence": "MPDSPVDVKTQSRLTPPTMPPPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPNHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGNSSSSHSRQQSPVNPDPVTLESHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMAELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGETPAVSSSVTPSSGAGSPIDTPPAATPRSTTPGTPSTIEATPR", "length": 533, "header": "tr|A0A8V0YH50-1|A0A8V0YH50_CHICK Computationally mapped isoform of RUNX1 translocation partner 1 OS=Gallus gallus OX=9031 GN=RUNX1T1 PE=4 SV=1 CANONICAL=A0A1D5PBA3-1" }, "locus": { "chromosome": "2", "start_pos": 124687172, "end_pos": 124641332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026940.1", "url": "https://www.ensembl.org/id/ENSGALT00010026940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015342.1", "url": "https://www.ensembl.org/id/ENSGALP00010015342.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 293, "start_aa": "T", "end_pos": 293, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr293", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 571, "start_aa": "T", "end_pos": 571, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr571", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 595, "start_aa": "T", "end_pos": 595, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr595", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Novel RNA-binding properties of the MTG chromatin regulatory proteins.", "journal": "BMC molecular biology", "date": "2008-10-24", "authors": "Rossetti Stefano, van Unen Leontine, Sacchi Nicoletta, Hoogeveen Andre T", "evidence": [ { "database": "RefSeq", "id": "NP_990075", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990075" } ], "reference": [ { "type": "PubMed", "id": "18950503", "url": "https://glygen.org/publication/PubMed/18950503" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0G0-1", "protein_name": "RUNX1 partner transcriptional co-repressor 1", "gene_name": "Runx1t1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MISIKRNTWRALSVVIGDCRKKANFEYCQDRTEKHSTMPDSPVDVKTQSRLTPPAMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSGSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAPQQGETPAVSSSVTPSSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 604 }, "evidence": [ { "id": "A0A1D5PBA3", "url": "https://omabrowser.org/oma/group/A0A1D5PBA3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9T181-1", "protein_name": "RUNX1 partner transcriptional co-repressor 1", "gene_name": "RUNX1T1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLAVCSLSLRAGQRLLSGVVSVYTGLNSHWKDRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGSSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 606 }, "evidence": [ { "id": "A0A1D5PBA3", "url": "https://omabrowser.org/oma/group/A0A1D5PBA3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RY37-1", "protein_name": "RUNX1 partner transcriptional co-repressor 1", "gene_name": "RUNX1T1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNTKPRSGCRLGCGRLSCAPLPEAGGENLHLKISRGRKRNLPFVVWGEEEASVLAWPLSPITSAIQTGLTEKRLISGLVNIISVPVRKGKRKLAERLVENDICQKKHLESTEFSNRYRTEKHSTMPDSPVDVKTPSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITSERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 691 }, "evidence": [ { "id": "A0A1D5PBA3", "url": "https://omabrowser.org/oma/group/A0A1D5PBA3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q06455-1", "protein_name": "Protein CBFA2T1", "gene_name": "RUNX1T1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISVKRNTWRALSLVIGDCRKKGNFEYCQDRTEKHSTMPDSPVDVKTQSRLTPPTMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGGSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQQGDTPAVSSSVTPNSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 604 }, "evidence": [ { "id": "A0A1D5PBA3", "url": "https://omabrowser.org/oma/group/A0A1D5PBA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61909-1", "protein_name": "Protein CBFA2T1", "gene_name": "Runx1t1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPDRTEKHSTMPDSPVDVKTQSRLTPPAMPPPPTTQGAPRTSSFTPTTLTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDASTTSPVDSSELLLDVNENGKRRTPDRTKENGFDREPLHSEHPSKRPCTISPGQRYSPNNGLSYQPNGLPHPTPPPPQHYRLDDMAIAHHYRDSYRHPSHRDLRDRNRPMGLHGTRQEEMIDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELNYWIRRYSDAEDLKKGGSSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEEIWKKAEEAVNEVKRQAMTELQKAVSEAERKAHDMITTERAKMERTVAEAKRQAAEDALAVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAPQQGDTPAVSSSVTPSSGAGSPMDTPPAATPRSTTPGTPSTIETTPR", "length": 577 }, "evidence": [ { "id": "A0A1D5PBA3", "url": "https://omabrowser.org/oma/group/A0A1D5PBA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PBA3", "url": "https://www.uniprot.org/uniprot/A0A1D5PBA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PBA3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 604, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PBA3-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 293, 571, 595 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 78, "end_pos": 80 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 3 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }