{ "uniprot_canonical_ac": "A0A1D5P9T4-1", "uniprot_ac": "A0A1D5P9T4", "uniprot_id": "A0A1D5P9T4_CHICK", "mass": { "chemical_mass": 102591.0, "monoisotopic_mass": 102591.0 }, "refseq": { "ac": "XP_015147673", "name": "protein unc-45 homolog A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673" }, "gene_names": [ { "name": "UNC45A", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4", "id": "A0A1D5P9T4" }, { "name": "UNC45A", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673", "id": "XP_015147673" } ], "protein_names": [ { "name": "Unc-45 myosin chaperone A", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4/entry#names_and_taxonomy", "id": "A0A1D5P9T4" }, { "name": "protein unc-45 homolog A isoform X2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673", "id": "XP_015147673" } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UNC45A", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4", "locus": { "chromosome": "10", "start_pos": 20103430, "end_pos": 20112395, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000056", "url": "https://www.ensembl.org/id/ENSGALG00010000056" } ] } } ], "crossref": [ { "id": "A0A1D5P9T4", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5P9T4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029714", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029714", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415584", "url": "https://www.ncbi.nlm.nih.gov/gene/415584", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45994", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45994", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45994:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45994:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11701", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_015147673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147673", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P9T4-1", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0WZD8", "url": "https://www.uniprot.org/uniprot/A0A8V0WZD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0WZD8-1", "url": "https://www.uniprot.org/uniprot/A0A8V0WZD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X639", "url": "https://www.uniprot.org/uniprot/A0A8V0X639", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X639-1", "url": "https://www.uniprot.org/uniprot/A0A8V0X639-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEETVTAGQLRERGNALFQAGDHAAALAAYTQALSLCQAEPERAVLHRNRAACYLKLEDYAKAEADASKAIEADGRDMKALFRRSQALQKLGRLDQAVSDLQRCVSLEPKNKAFQEALRTLGSSMHEKMKTMSCTDSKVEQMFQILLDPQEKDVDKKQKAAQNLIVLAREEAGAEKIFQSDGVRLLTQLLDTAKADLMLAALRTLVGLCSGHRSRSMAILTELGSSRLSAVLGVEHEQVSLAACNLLHVMFDSLKEGMQKDFRGKEDAVVLDSSKEQKVLIKDLLELLPLEGASAHGRDNALNLLIKVVPRKSPKDINNSMTLWVIDQGLKKILEVGSTVCGAPDSLPVTENSRMSASVLLSKLYDDLKCDAERENFHHLCEDYVRSWFEGQELAGKLRAIQTVSCLLQGPSEAGNRVLELEGIMDSILSLCASVREAHQLVAVEALIHAADKAKRASFITANGVSLLKEIYKHSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTMKLAKQCRKWLCNEAIDAGTRRWAVEGLAYLTFDADVKEEFVEDKAAMQAMFQLTKSEDRSVLYAVASTLVNCTNSYDHEEPDPQMLELAKYAKQHIPEQHPKDKPDFVKRRVRKLLTAGVVSALACVVKSENPALTNSCRELISRVFLALVAEAEDRGCVVAQGGGKALIPLSLEGTEVGQTKAAQALAKITITSNPEMAFPGERIYEVVRPLVSLLHLQRSGLENFEGLMALTNLAGISERLRQKIVKERAVPMIEGYMFEEHELIRLAATECMCNMAMSKEVQELFLDEGSDRLKLMVLYSGEEDEKLRRAASGTLAMLTALHPPICKRIPRVTVHWLEILQALLLSPSAELQHRGAVVVMNMMAAAREVAEQLIASEMLEILSVLAKDEDKPRVAQAAQESLARAVAYGLIEPNPRQQ", "length": 931, "header": "tr|A0A1D5P9T4-1|A0A1D5P9T4_CHICK Isoform 1 of Unc-45 myosin chaperone A OS=Gallus gallus OX=9031 GN=UNC45A PE=1 SV=1 CANONICAL=A0A1D5P9T4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P9T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4/entry#A0A1D5P9T4-1", "sequence": { "sequence": "MEETVTAGQLRERGNALFQAGDHAAALAAYTQALSLCQAEPERAVLHRNRAACYLKLEDYAKAEADASKAIEADGRDMKALFRRSQALQKLGRLDQAVSDLQRCVSLEPKNKAFQEALRTLGSSMHEKMKTMSCTDSKVEQMFQILLDPQEKDVDKKQKAAQNLIVLAREEAGAEKIFQSDGVRLLTQLLDTAKADLMLAALRTLVGLCSGHRSRSMAILTELGSSRLSAVLGVEHEQVSLAACNLLHVMFDSLKEGMQKDFRGKEDAVVLDSSKEQKVLIKDLLELLPLEGASAHGRDNALNLLIKVVPRKSPKDINNSMTLWVIDQGLKKILEVGSTVCGAPDSLPVTENSRMSASVLLSKLYDDLKCDAERENFHHLCEDYVRSWFEGQELAGKLRAIQTVSCLLQGPSEAGNRVLELEGIMDSILSLCASVREAHQLVAVEALIHAADKAKRASFITANGVSLLKEIYKHSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTMKLAKQCRKWLCNEAIDAGTRRWAVEGLAYLTFDADVKEEFVEDKAAMQAMFQLTKSEDRSVLYAVASTLVNCTNSYDHEEPDPQMLELAKYAKQHIPEQHPKDKPDFVKRRVRKLLTAGVVSALACVVKSENPALTNSCRELISRVFLALVAEAEDRGCVVAQGGGKALIPLSLEGTEVGQTKAAQALAKITITSNPEMAFPGERIYEVVRPLVSLLHLQRSGLENFEGLMALTNLAGISERLRQKIVKERAVPMIEGYMFEEHELIRLAATECMCNMAMSKEVQELFLDEGSDRLKLMVLYSGEEDEKLRRAASGTLAMLTALHPPICKRIPRVTVHWLEILQALLLSPSAELQHRGAVVVMNMMAAAREVAEQLIASEMLEILSVLAKDEDKPRVAQAAQESLARAVAYGLIEPNPRQQ", "length": 931, "header": "tr|A0A1D5P9T4-1|A0A1D5P9T4_CHICK Isoform 1 of Unc-45 myosin chaperone A OS=Gallus gallus OX=9031 GN=UNC45A PE=1 SV=1 CANONICAL=A0A1D5P9T4-1" }, "locus": { "chromosome": "10", "start_pos": 20112356, "end_pos": 20106229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000090.1", "url": "https://www.ensembl.org/id/ENSGALT00010000090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000066.1", "url": "https://www.ensembl.org/id/ENSGALP00010000066.1" } ] } }, { "isoform_ac": "A0A8V0WZD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4/entry#A0A8V0WZD8-1", "sequence": { "sequence": "MEETVTAGQLRERGNALFQAGDHAAALAAYTQALSLCQAEPERAVLHRNRAACYLKLEDYAKAEADASKAIEADGRDMKALFRRSQALQKLGRLDQAVSDLQRCVSLEPKNKAFQEALRTLGSSMHEKMKTMSCTDSKVEQMFQILLDPQEKDVDKKQKAAQNLIVLAREEAGAEKIFQSDGVRLLTQLLDTAKADLMLAALRTLVGLCSGHRSRSMAILTELGSSRLSAVLGVEHEQVSLAACNLLHVMFDSLKEGMQKDFRGKEDAVVLDSSKEQKVLIKDLLELLPLEGASAHGRDNALNLLIKVVPRKSPKDINNSMTLWVIDQGLKKILEVGSTVCGAPDSLPVTENSRMSASVLLSKLYDDLKCDAERENFHHLCEDYVRSWFEGQELAGKLRAIQTVSCLLQGPSEAGNRVLELEGIMDSILSLCASVREAHQLVAVEALIHAADKAKRASFITANGVSLLKEIYKHSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTMKLAKQCRKWLCNEAIDAGTRRWAVEGLAYLTFDADVKEEFVEDKAAMQAMFQLTKSEDRSVLYAVASTLVNCTNSYDHEEPDPQMLELAKYAKQHIPEQHPKDKPDFVKRRVRKLLTAGVVSALACVVKSENPALTNSCRELISRVFLALVAEAEDRGCVVAQGGGKALIPLSLEGTEVGQTKAAQALAKITITSNPEMAFPGERIYEVVRPLVSLLHLQRSGLENFEGLMALTNLAGISERLRQKIVKERAVPMIEGYMFEEHELIRLAATECMCNMAMSKEVQELFLDEGSDRLKLMVLYSGEEDEKLRRAASGTLAMLTALHPPICKRIPRVAWAARPRQPGIRAAAAAGGGSGRCAHAGGGSWRVALGLCQRRGRPLCVGLERVGPTGAALPGGGRGAGRG", "length": 915, "header": "tr|A0A8V0WZD8-1|A0A1D5P9T4_CHICK Computationally mapped isoform of Unc-45 myosin chaperone A OS=Gallus gallus OX=9031 GN=UNC45A PE=1 SV=1 CANONICAL=A0A1D5P9T4-1" }, "locus": { "chromosome": "10", "start_pos": 20112356, "end_pos": 20103447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000091.1", "url": "https://www.ensembl.org/id/ENSGALT00010000091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000067.1", "url": "https://www.ensembl.org/id/ENSGALP00010000067.1" } ] } }, { "isoform_ac": "A0A8V0X639-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P9T4/entry#A0A8V0X639-1", "sequence": { "sequence": "MGSVRDPAWAVFWEGQDTALCCFPVLRGVVSIPELHGCFFACFVKQCAQQEDYAKAEADASKAIEADGRDMKALFRRSQALQKLGRLDQAVSDLQRCVSLEPKNKAFQEALRTLGSSMHEKMKTMSCTDSKVEQMFQILLDPQEKDVDKKQKAAQNLIVLAREEAGAEKIFQSDGVRLLTQLLDTAKADLMLAALRTLVGLCSGHRSRSMAILTELGSSRLSAVLGVEHEQVSLAACNLLHVMFDSLKEGMQKDFRGKEDAVVLDSSKEQKVLIKDLLELLPLEGASAHGRDNALNLLIKVVPRKSPKDINNSMTLWVIDQGLKKILEVGSTVCGAPDSLPVTENSRMSASVLLSKLYDDLKCDAERENFHHLCEDYVRSWFEGQELAGKLRAIQTVSCLLQGPSEAGNRVLELEGIMDSILSLCASVREAHQLVAVEALIHAADKAKRASFITANGVSLLKEIYKHSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTMKLAKQCRKWLCNEAIDAGTRRWAVEGLAYLTFDADVKEEFVEDKAAMQAMFQLTKSEDRSVLYAVASTLVNCTNSYDHEEPDPQMLELAKYAKQHIPEQHPKDKPDFVKRRVRKLLTAGVVSALACVVKSENPALTNSCRELISRVFLALVAEAEDRGCVVAQGGGKALIPLSLEGTEVGQTKAAQALAKITITSNPEMAFPGERIYEVVRPLVSLLHLQRSGLENFEGLMALTNLAGISERLRQKIVKERAVPMIEGYMFEEHELIRLAATECMCNMAMSKEVQELFLDEGSDRLKLMVLYSGEEDEKLRRAASGTLAMLTALHPPICKRIPRVTVHWLEILQALLLSPSAELQHRGAVVVMNMMAAAREVAEQLIASEMLEILSVLAKDEDKPRVAQAAQESLARAVAYGLIEPNPRQQ", "length": 924, "header": "tr|A0A8V0X639-1|A0A8V0X639_CHICK Computationally mapped isoform of Unc-45 myosin chaperone A OS=Gallus gallus OX=9031 GN=UNC45A PE=1 SV=1 CANONICAL=A0A1D5P9T4-1" }, "locus": { "chromosome": "10", "start_pos": 20111738, "end_pos": 20106229, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000089.1", "url": "https://www.ensembl.org/id/ENSGALT00010000089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000065.1", "url": "https://www.ensembl.org/id/ENSGALP00010000065.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P9T4", "url": "https://www.uniprot.org/uniprot/A0A1D5P9T4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5P9T4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 931, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5P9T4-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 318, "end_pos": 320 }, { "start_pos": 581, "end_pos": 583 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }