{ "uniprot_canonical_ac": "A0A140LIS8-1", "uniprot_ac": "A0A140LIS8", "uniprot_id": "A0A140LIS8_MOUSE", "mass": { "chemical_mass": 37840.0, "monoisotopic_mass": 37840.0 }, "refseq": {}, "gene_names": [ { "name": "Dhrs7l", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A140LIS8", "id": "A0A140LIS8" }, { "name": "Gm4756", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A140LIS8", "id": "A0A140LIS8" } ], "protein_names": [ { "name": "Dehydrogenase/reductase (SDR family) member 7 like 1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A140LIS8/entry#names_and_taxonomy", "id": "A0A140LIS8" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A140LIS8", "url": "https://www.uniprot.org/uniprot/A0A140LIS8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "gene": [ { "name": "Dhrs7l", "url": "https://www.uniprot.org/uniprot/A0A140LIS8", "locus": { "chromosome": "12", "start_pos": 72622776, "end_pos": 72696435, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000109482", "url": "https://www.ensembl.org/id/ENSMUSG00000109482" } ] } } ], "crossref": [ { "id": "A0A140LIS8", "url": "https://alphafold.ebi.ac.uk/entry/A0A140LIS8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSMUSG00000109482", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000109482", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05332", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05332", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "3644906", "url": "http://www.informatics.jax.org/marker/MGI:3644906", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "TERCAYL", "url": "https://omabrowser.org/oma/group/TERCAYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR44269", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44269", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44269:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44269:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "A0A140LI79", "url": "https://www.uniprot.org/uniprot/A0A140LI79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LI79-1", "url": "https://www.uniprot.org/uniprot/A0A140LI79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LIS8", "url": "https://www.uniprot.org/uniprot/A0A140LIS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LIS8-1", "url": "https://www.uniprot.org/uniprot/A0A140LIS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LIU7", "url": "https://www.uniprot.org/uniprot/A0A140LIU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LIU7-1", "url": "https://www.uniprot.org/uniprot/A0A140LIU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LJ41", "url": "https://www.uniprot.org/uniprot/A0A140LJ41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LJ41-1", "url": "https://www.uniprot.org/uniprot/A0A140LJ41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LJG4", "url": "https://www.uniprot.org/uniprot/A0A140LJG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LJG4-1", "url": "https://www.uniprot.org/uniprot/A0A140LJG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1Y7VJD4", "url": "https://www.uniprot.org/uniprot/A0A1Y7VJD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1Y7VJD4-1", "url": "https://www.uniprot.org/uniprot/A0A1Y7VJD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIEFWILALCALLLPAFGLLSFLRLDSDLTLLWASWMGRRPEQALIGMVVWVTGASSGIGEELAFQLSKLGVSLVLSARRAQELERVKRRCLENGNMRENDILVLPLDLADTSSHDIATKAVLQEFGRIDILVNNGGETNYCFAVDANLDVFKVLMEVNYLGTVSLTKSVLPHMMERKQGKIVIMNSLAGIVPSPLCCGYIASKHALRGFANALRTELLDHPGITLSTICPGPVHSNIYQNYLTREAIKARWPKPQEFPKMATSRCVQLILVSMANDLEEVWIANQPALFRTYVWQYVPIRDWIISRTQWKKRIEIFRITMDDPEGDHDKRPSK", "length": 335, "header": "tr|A0A140LIS8-1|A0A140LIS8_MOUSE Isoform 1 of Dehydrogenase/reductase (SDR family) member 7 like 1 OS=Mus musculus OX=10090 GN=Dhrs7l PE=1 SV=1 CANONICAL=A0A140LIS8-1" }, "isoforms": [ { "isoform_ac": "A0A140LI79-1", "url": "https://www.uniprot.org/uniprotkb/A0A140LIS8/entry#A0A140LI79-1", "sequence": { "sequence": "MDIEFWILALCALLLPAFGLLSFLRLDSDLTLLWASWMGRRPGENLL", "length": 47, "header": "tr|A0A140LI79-1|A0A140LI79_MOUSE Computationally mapped isoform of Dehydrogenase/reductase (SDR family) member 7 like 1 OS=Mus musculus OX=10090 GN=Dhrs7l PE=4 SV=1 CANONICAL=A0A140LIS8-1" }, "locus": {} }, { "isoform_ac": "A0A140LIS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A140LIS8/entry#A0A140LIS8-1", "sequence": { "sequence": "MDIEFWILALCALLLPAFGLLSFLRLDSDLTLLWASWMGRRPEQALIGMVVWVTGASSGIGEELAFQLSKLGVSLVLSARRAQELERVKRRCLENGNMRENDILVLPLDLADTSSHDIATKAVLQEFGRIDILVNNGGETNYCFAVDANLDVFKVLMEVNYLGTVSLTKSVLPHMMERKQGKIVIMNSLAGIVPSPLCCGYIASKHALRGFANALRTELLDHPGITLSTICPGPVHSNIYQNYLTREAIKARWPKPQEFPKMATSRCVQLILVSMANDLEEVWIANQPALFRTYVWQYVPIRDWIISRTQWKKRIEIFRITMDDPEGDHDKRPSK", "length": 335, "header": "tr|A0A140LIS8-1|A0A140LIS8_MOUSE Isoform 1 of Dehydrogenase/reductase (SDR family) member 7 like 1 OS=Mus musculus OX=10090 GN=Dhrs7l PE=1 SV=1 CANONICAL=A0A140LIS8-1" }, "locus": { "chromosome": "12", "start_pos": 72675627, "end_pos": 72655730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000208039.2", "url": "https://www.ensembl.org/id/ENSMUST00000208039.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000146943.2", "url": "https://www.ensembl.org/id/ENSMUSP00000146943.2" } ] } }, { "isoform_ac": "A0A140LIU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A140LIS8/entry#A0A140LIU7-1", "sequence": { "sequence": "MDIEFWILALCALLLPAFGLLSFLRLDSDLTLLWASWMGRRPENGNMRENDILVLPLDLADTSSHDIATKAVLQEFGRIDILVNNGGETNYCFAVDANLDVFKVLMEVNYLGTVSLTKSVLPHMMERKQGKIVIMNSLAGIVPSPLCCGYIASKHALRDDPEGDHDKRPSK", "length": 171, "header": "tr|A0A140LIU7-1|A0A140LIU7_MOUSE Computationally mapped isoform of Dehydrogenase/reductase (SDR family) member 7 like 1 OS=Mus musculus OX=10090 GN=Dhrs7l PE=4 SV=1 CANONICAL=A0A140LIS8-1" }, "locus": { "chromosome": "12", "start_pos": 72675627, "end_pos": 72655730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000207585.2", "url": "https://www.ensembl.org/id/ENSMUST00000207585.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000146963.2", "url": "https://www.ensembl.org/id/ENSMUSP00000146963.2" } ] } }, { "isoform_ac": "A0A140LJ41-1", "url": "https://www.uniprot.org/uniprotkb/A0A140LIS8/entry#A0A140LJ41-1", "sequence": { "sequence": "MDIEFWILALCALLLPAFGLLSFLRLDSDLTLLWASWMGRRPENGNMRENDILVLPLDLADTSSHDIATKAVLQEFGRIDILVNNGGETNYCFAVDANLDVFKVLMEVNYLGTVSLTKSVLPHMMERKQGKIVIMNSLAGIVPSPLCCGYIASKHALRVRLFQLNSVSIDCNVHGGFVHQWVRLMELRDNGPQKENNFEATTPVNNQKY", "length": 209, "header": "tr|A0A140LJ41-1|A0A140LJ41_MOUSE Computationally mapped isoform of Dehydrogenase/reductase (SDR family) member 7 like 1 OS=Mus musculus OX=10090 GN=Dhrs7l PE=4 SV=1 CANONICAL=A0A140LIS8-1" }, "locus": { "chromosome": "12", "start_pos": 72675627, "end_pos": 72666043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000209038.2", "url": "https://www.ensembl.org/id/ENSMUST00000209038.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000147067.2", "url": "https://www.ensembl.org/id/ENSMUSP00000147067.2" } ] } }, { "isoform_ac": "A0A140LJG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A140LIS8/entry#A0A140LJG4-1", "sequence": { "sequence": "MRENDILVLPLDLADTSSHDIATKAVLQEFGRIDILVNNGGETNYCFAVDANLDVFKVLMEVNYLGTVSLTKSVLPHMMERKQGKIVIMNSLAGIVPSPLCCGYIASKHALRGFANALRTELLDHPGITLSTICPGPVHSNIYQNYLTREAIKARWPKPQEFPKMATSRCVQLILVSMANDLEEVWIANQPALFRTYVWQYVPIRDWIISRTQWKKRIEIFRITMV", "length": 226, "header": "tr|A0A140LJG4-1|A0A140LJG4_MOUSE Computationally mapped isoform of Dehydrogenase/reductase (SDR family) member 7 like 1 OS=Mus musculus OX=10090 GN=Dhrs7l PE=1 SV=1 CANONICAL=A0A140LIS8-1" }, "locus": { "chromosome": "12", "start_pos": 72668717, "end_pos": 72658487, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000208307.2", "url": "https://www.ensembl.org/id/ENSMUST00000208307.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000147204.2", "url": "https://www.ensembl.org/id/ENSMUSP00000147204.2" } ] } }, { "isoform_ac": "A0A1Y7VJD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A140LIS8/entry#A0A1Y7VJD4-1", "sequence": { "sequence": "XILALCALLLPAFGLLSFLRLDSDLTLLWASWMGRRPEQALIGMVVWVTGASSGIGEELAFQLSKLGVSLVLSARRAQELERVKRRCLENGNMRENDILVLPLDLADTSSHDIATKAVLQEFGRIDILVNNGGETNYCFAVDANLDVFKVLMEVNYLGTVSLTKSVLPHMMERKQGKIVIMNSLAGIVPSPLCCGYIASKHALRAGPHTAQDRAVFCVPEDGCEVLILLGNGMCPGPSVSSS", "length": 242, "header": "tr|A0A1Y7VJD4-1|A0A1Y7VJD4_MOUSE Computationally mapped isoform of Dehydrogenase/reductase (SDR family) member 7 like 1 OS=Mus musculus OX=10090 GN=Dhrs7l PE=1 SV=1 CANONICAL=A0A140LIS8-1" }, "locus": { "chromosome": "12", "start_pos": 72675611, "end_pos": 72624542, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000222413.2", "url": "https://www.ensembl.org/id/ENSMUST00000222413.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000152376.2", "url": "https://www.ensembl.org/id/ENSMUSP00000152376.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "M0R4N4-1", "protein_name": "Dehydrogenase/reductase SDR family member 7-like", "gene_name": "LOC120093108", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VMGFEFWMLALCALLLLVLGLLSFLWLDSDLTLLRAAWMGQCPEQALADKVVWITGASSGIGEELAFQLSKLGVCLVLSARRGQELERVKRRCLENGNLKEKDILVLPLDLADTSSHDIATKTVLQEFGRIDILVNNGGIVHASLFENTNLDVFKVLIEVNYFGTVSLTKCVLPHMMERKQGKIVVMNSLVGIVPNPLCSGYIASKFALRGFVGALRTELFDYPGIRLSTICPGHVHSNIFQNFITGEFTKTRLPEIPLFMMETSRCVQLILVSLANDLEEVWIANQPVLLRAYVWQYVPFRDWILQGCYGKYISKALGITWYV", "length": 324 }, "evidence": [ { "id": "A0A140LIS8", "url": "https://omabrowser.org/oma/group/A0A140LIS8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A140LIS8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 335, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A140LIS8-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }