{ "uniprot_canonical_ac": "A0A0G2KB61-1", "uniprot_ac": "A0A0G2KB61", "uniprot_id": "A0A0G2KB61_RAT", "mass": { "chemical_mass": 119113.0, "monoisotopic_mass": 119113.0 }, "refseq": {}, "gene_names": [ { "name": "Ppp1r13b", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61", "id": "A0A0G2KB61" } ], "protein_names": [ { "name": "Protein phosphatase 1, regulatory subunit 13B", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB61/entry#names_and_taxonomy", "id": "A0A0G2KB61" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Ppp1r13b", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61", "locus": { "chromosome": "6", "start_pos": 130890679, "end_pos": 130963330, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000012653", "url": "https://www.ensembl.org/id/ENSRNOG00000012653" } ] } } ], "crossref": [ { "id": "A0A0G2KB61", "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2KB61", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSRNOG00000012653", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000012653", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "314465", "url": "https://www.ncbi.nlm.nih.gov/gene/314465", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GFQSHNG", "url": "https://omabrowser.org/oma/group/GFQSHNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "D4A6A8", "url": "https://www.orthodb.org/?gene=D4A6A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24131:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24131:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF21801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21801", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-6804759", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6804759", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "1304651", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1304651", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2KB61-1", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A8S6", "url": "https://www.uniprot.org/uniprot/A0A8I6A8S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A8S6-1", "url": "https://www.uniprot.org/uniprot/A0A8I6A8S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D4A6A8", "url": "https://www.uniprot.org/uniprot/D4A6A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D4A6A8-1", "url": "https://www.uniprot.org/uniprot/D4A6A8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCHLAEVWRGSERPIPCDHMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGARQSQEQRTQRNVMNVPGEKHTENGVGNPRVELTLSELQDMAARQQQQIESQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGRLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSTGGFPLPGDPVKPQSLTIASSAAHGRSKSANDGNWPTLKQNSASVKSTQMAGGDWKDSGMEGTLKQGAISSQPLPLSALGATDKLGIEIGKGPPPIPGVGKPLPPSYGTYPSPGPLGPGSTSSLERRKEGSLPRPAAGPPSRQKPAPLPPAGSAPQPSSSQQIQQRISVPPSPTYPPAGPPAFPAGDGKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLPFLHGSLGTGTTQPQPPSECAEKEAEPEGPSVPGEGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFVGTLADVDNGNTNANGNLDESFPPRPTAPLPDELAPSSDANDNELPSPEPEELICPQTTHQTAEPTEDNNNNVATVPSTEQIPSPVAEAPSEEDQVPPAPLSPVVHPPTASASKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGIVYALWDYEAQNNDELSFHEGDAITILRRKDENETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA", "length": 1088, "header": "tr|A0A0G2KB61-1|A0A0G2KB61_RAT Isoform 1 of Protein phosphatase 1, regulatory subunit 13B OS=Rattus norvegicus OX=10116 GN=Ppp1r13b PE=1 SV=2 CANONICAL=A0A0G2KB61-1" }, "isoforms": [ { "isoform_ac": "A0A0G2KB61-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB61/entry#A0A0G2KB61-1", "sequence": { "sequence": "MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCHLAEVWRGSERPIPCDHMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGARQSQEQRTQRNVMNVPGEKHTENGVGNPRVELTLSELQDMAARQQQQIESQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGRLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSTGGFPLPGDPVKPQSLTIASSAAHGRSKSANDGNWPTLKQNSASVKSTQMAGGDWKDSGMEGTLKQGAISSQPLPLSALGATDKLGIEIGKGPPPIPGVGKPLPPSYGTYPSPGPLGPGSTSSLERRKEGSLPRPAAGPPSRQKPAPLPPAGSAPQPSSSQQIQQRISVPPSPTYPPAGPPAFPAGDGKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLPFLHGSLGTGTTQPQPPSECAEKEAEPEGPSVPGEGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFVGTLADVDNGNTNANGNLDESFPPRPTAPLPDELAPSSDANDNELPSPEPEELICPQTTHQTAEPTEDNNNNVATVPSTEQIPSPVAEAPSEEDQVPPAPLSPVVHPPTASASKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGIVYALWDYEAQNNDELSFHEGDAITILRRKDENETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA", "length": 1088, "header": "tr|A0A0G2KB61-1|A0A0G2KB61_RAT Isoform 1 of Protein phosphatase 1, regulatory subunit 13B OS=Rattus norvegicus OX=10116 GN=Ppp1r13b PE=1 SV=2 CANONICAL=A0A0G2KB61-1" }, "locus": { "chromosome": "6", "start_pos": 130962562, "end_pos": 130891740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000082600.2", "url": "https://www.ensembl.org/id/ENSRNOT00000082600.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000075666.2", "url": "https://www.ensembl.org/id/ENSRNOP00000075666.2" } ] } }, { "isoform_ac": "A0A8I6A8S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB61/entry#A0A8I6A8S6-1", "sequence": { "sequence": "MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCHLAEVWRGSERPIPCDHMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGARQSQEQRTQRNVMNVPGEKHTENGVGNPRVELTLSELQDMAARQQQQIESQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGRLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSTGGFPLPGDPVKPQSLTIASSAAHGRSKSDGYSRCRGTSTWTVSDLDIGPHCGSSGHSASPLVNSNDGNWPTLKQNSASVKSTQMAGGDWKDSGMEGTLKQGAISSQPLPLSALGATDKLGIEIGKGPPPIPGVGKPLPPSYGTYPSPGPLGPGSTSSLERRKEGSLPRPAAGPPSRQKPAPLPPAGSAPQPSSSQQIQQRISVPPSPTYPPAGPPAFPAGDGKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLPFLHGSLGTGTTQPQPPSECAEKEAEPEGPSVPGEGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFVGTLADVDNGNTNANGNLDESFPPRPTAPLPDELAPSSDANDNELPSPEPEELICPQTTHQTAEPTEDNNNNVATVPSTEQIPSPVAEAPSEEDQVPPAPLSPVVHPPTASASKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGIVYALWDYEAQNNDELSFHEGDAITILRRKDENETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA", "length": 1123, "header": "tr|A0A8I6A8S6-1|A0A8I6A8S6_RAT Computationally mapped isoform of Protein phosphatase 1, regulatory subunit 13B OS=Rattus norvegicus OX=10116 GN=Ppp1r13b PE=4 SV=1 CANONICAL=A0A0G2KB61-1" }, "locus": { "chromosome": "6", "start_pos": 130962562, "end_pos": 130891740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000097238.1", "url": "https://www.ensembl.org/id/ENSRNOT00000097238.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000088786.1", "url": "https://www.ensembl.org/id/ENSRNOP00000088786.1" } ] } }, { "isoform_ac": "D4A6A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KB61/entry#D4A6A8-1", "sequence": { "sequence": "MILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCHLAEVWRGSERPIPCDHMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGARQSQEQRTQRNVMNVPGEKHTENGEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGRLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQAPEPCEWDIITTVTPEHIRPGRCCGSLYPGDPVKPQSLTIASSAAHGRSKSANDGNWPTLKQNSASVKSTQMAGGDWKDSGMEGTLKQGAISSQPLPLSALGATDKLGIEIGKGPPPIPGVGKPLPPSYGTYPSPGPLGPGSTSSLERRKEGSLPRPAAGPPSRQKPAPLPPAGSAPQPSSSQQIQQRISVPPSPTYPPAGPPAFPAGDGKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLPFLHGSLGTGTTQPQPPSECAEKEAEPEGPSVPGEGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFVGTLADVDNGNTNANGNLDESFPPRPTAPLPDELAPSSDANDNELPSPEPEELICPQTTHQTAEPTEDNNNNVATVPSTEQIPSPVAEAPSEEDQVPPAPLSPVVHPPTASASKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGIVYALWDYEAQNNDELSFHEGDAITILRRKDENETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA", "length": 1042, "header": "tr|D4A6A8-1|D4A6A8_RAT Computationally mapped isoform of Protein phosphatase 1, regulatory subunit 13B OS=Rattus norvegicus OX=10116 GN=Ppp1r13b PE=1 SV=1 CANONICAL=A0A0G2KB61-1" }, "locus": { "chromosome": "6", "start_pos": 130929649, "end_pos": 130891740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000067118.3", "url": "https://www.ensembl.org/id/ENSRNOT00000067118.3" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000059338.1", "url": "https://www.ensembl.org/id/ENSRNOP00000059338.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 777, "start_aa": "T", "end_pos": 777, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr777", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] } ], "pathway": [ { "id": "R-RNO-6804759", "name": "Regulation of TP53 Activity through Association with Co-factors", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6804759", "resource": "Reactome", "description": "Regulation of TP53 Activity through Association with Co-factors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LWL2-1", "protein_name": "Protein phosphatase 1 regulatory subunit 13B", "gene_name": "PPP1R13B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDYMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGGRQTQEQRTQRNVTNVPGEKRTENGVGNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQPYSGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNVEVAMMDKRISELRERLYGKKTQLSRVNGTSSPQSPLSAPGRVAAVGPYIQVPSTGSCPAPGDPAKPQSLTVASSAAHGRSKSDGRGQPRATRLWTVSHLDAGPGRGPSQCPASPFAKPNDGNWPTLKQNSSSSVRPPQMAGVDWKDASAEGPLKQGAVSSQPVSLSALSAPEKLGMEIGKVPPPLPGVSKPLPPSYGTYPSPAPVGPGSTNSLERRKEGSLPRPSAGLPSRQKPAPLPPAGGPHQPGSSQQIQQRISVPPSPTYPPAGLPAFPAGDGKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSTVNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLAPGATQPPPPGESAEKEPEPESPAPPGDGAVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGAPFYQPSPSQDFLGSLADVDNGNTTANGNLGEAGPTPLPAPLPAEPAPASDANDNRLPSPEPEGLLCPPNTHQTAEPAEDDNNNVATAPSTEQAPSPGAEAPSPGEEQAPPALPLSVASTSKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRVIYEVEDPSKPNDEGITPLHNAVCAGHHHIVRFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVVYALWAYEAQNSDELTFREGDALTILRRKDEVETDWWWARLGDREGYVPRNLLGLYPRIKPRQRTLA", "length": 1119 }, "evidence": [ { "id": "A0A0G2KB61", "url": "https://omabrowser.org/oma/group/A0A0G2KB61/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q62415-1", "protein_name": "Apoptosis-stimulating of p53 protein 1", "gene_name": "Ppp1r13b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCHLAEVWRGSERPIPYDHMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGARQTQEQRTQRSVVNVPGEKRTENGVGNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSVSENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGRLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSTGGFPLPGDPVKPQSLTIASSAAHGRSKSANDGNWPPLKQNSASVKSTQMTGDWKDSGMEGTLKQGAISSQPLPLSALGATEKLGIEIGKGPPPIPGVGKPLPPSYGTYPSSGPLGPGSTSSLERRKEGSLPRPGAGPPSRQKPAPLPPASNAPQPGSSQQIQQRISVPPSPTYPPAGPPAFPTGDGKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLPFLHGSLGTGTAQPQPPSDSAEKEPEQEGPSVPGEGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFVGTLADMDNGNTNANGNLDEPFPPRPTAPLPEELAPSSDANDNELPSPEPEELICPQTTHQTAEPTEDNNNNVAPVPSTEQIPSPVAEAPSEEDQVPPAPLSPVIHPPAASASKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGTVYALWDYEAQNSDELSFHEGDAITILRRKDENETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA", "length": 1087 }, "evidence": [ { "id": "47558073", "url": "http://www.informatics.jax.org/homology/47558073", "database": "MGI" }, { "id": "A0A0G2KB61", "url": "https://omabrowser.org/oma/group/A0A0G2KB61/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86BG1-1", "protein_name": "Ankyrin-repeat, SH3-domain, and Proline-rich-region containing protein, isoform B", "gene_name": "ASPP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLTCVCRPVSGNLPKMPPASLMPAHRASASSASSSTSSTASLAFVSPTRGVVVTSEPKLNVPSRLTSAELRAMALRQQQQIDSQHQLLATKEQRLRFLKSQEVRSAVASAEGERLRRLRERVEAQESKLRRLRALRGQVDLQKTYNVTLSNDLDSIRALFSEKEKELSLAVAKVEALTRQLEELRRDRRCPVNILTAAGNGVGGQSLPPQASRELEKLRRELMYRNQLSLQQDARLHMQREALQQRQAELRSTDQRIYELQTRLQRKKQANTHHQQQQQQQQQHQQQQHQQQHQQTTVQQQQQQQQQLHVQSAQLLAAAAAATAQQQQQHQQHQQQQQQQQQQSASNLGKHGGVAALKQQLLQKQVNQLAAAAAAAAAGRARGNVAAVEPFIHTPQKSTITSTASYLSGGMKHAAATANTNQQNQLIQDLTHVKLGQNSGFFAGSVPVPVASSSCESDESKLAKKLLAAPAKTEAELRKQAQTEAMDSTTHIYAEVGPKKRDREAAAAAAAAAAAAAAAAQAAAEAANQAATAAAASAISPPATANASKIPKSTTSSSSSASALISKLNQQATAKESQDQQQSQAKKNEISVTSETLSERNTQQQLTVHSMPLGAISKSVALAVSNASKPLQVQVSNVAVPPRKPISSVAPNSVSSGSSIPKMITYSPKVNRVAPNVVMTDPRPALPPKPSKMSPTEQPSPVEANTSGSAGGAGSGAASASTANKTQTATFGLQSLNINDNLPIKAKPLTIRKQPLFEQPRLKSSQSSSNGQQKPPLLQLQNQRKSEPSARQPTENLPDTSPQHSPSSESSADETDRMVAPSITTSQQETSTSATSTTTTVTTSNIKERTGNGKPKLGRRVSFDPLALLLDASLEGELELVKKTAMQVANPSAANDEGITALHNAICAGHIDIVKFLVEFGCDVNAQDSDGWTPLHCAASCNNLSMVKFLVESGACLFASTLSDHETPAEKCEEDEEGFDGCSEYLYSIQEKLGILHNGDVYAVFSYEAQNGDELSFHVNEPLIVLRKGDDAENEWWWARNAAGEEGYVPRNLLGLYPRVPPHSPHFSD", "length": 1069 }, "evidence": [ { "id": "A0A0G2KB61", "url": "https://omabrowser.org/oma/group/A0A0G2KB61/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q96KQ4-1", "protein_name": "Apoptosis-stimulating of p53 protein 1", "gene_name": "PPP1R13B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDHMMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGVGNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA", "length": 1090 }, "evidence": [ { "id": "47558073", "url": "http://www.informatics.jax.org/homology/47558073", "database": "MGI" }, { "id": "A0A0G2KB61", "url": "https://omabrowser.org/oma/group/A0A0G2KB61/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "pmid": "" }, { "name": "negative regulation of cell cycle", "id": "GO:0045786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045786", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KB61", "url": "https://www.uniprot.org/uniprot/A0A0G2KB61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1053, "end_pos": 1055, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A0G2KB61-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1088, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0G2KB61-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 777 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1053, "end_pos": 1055 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 574, "end_pos": 576 }, { "start_pos": 601, "end_pos": 603 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }