{ "uniprot_canonical_ac": "A0A0G2KAB0-1", "uniprot_ac": "A0A0G2KAB0", "uniprot_id": "A0A0G2KAB0_RAT", "mass": { "chemical_mass": 59219.0, "monoisotopic_mass": 59219.0 }, "refseq": {}, "gene_names": [ { "name": "Hhla1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2KAB0", "id": "A0A0G2KAB0" }, { "name": "AABR07058254.1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0G2KAB0", "id": "A0A0G2KAB0" } ], "protein_names": [ { "name": "HERV-H LTR-associating 1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KAB0/entry#names_and_taxonomy", "id": "A0A0G2KAB0" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAB0", "url": "https://www.uniprot.org/uniprot/A0A0G2KAB0" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Hhla1", "url": "https://www.uniprot.org/uniprot/A0A0G2KAB0", "locus": {} } ], "crossref": [ { "id": "A0A0G2KAB0", "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2KAB0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR037643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MEAMRYC", "url": "https://omabrowser.org/oma/group/MEAMRYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15299", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15299", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15299:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15299:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "15008789", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=15008789", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2KAB0", "url": "https://www.uniprot.org/uniprot/A0A0G2KAB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2KAB0-1", "url": "https://www.uniprot.org/uniprot/A0A0G2KAB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSFPLHGPPMRLCMGLAYILSLWNAVSGLKGEGKKDKELALLPAAVSGNEGLKNEKYGSFLHTAESAFREKKTVKGVEVLATTELPARSVDLSALNLTELVNGMLSRALKDSKQFFSVLSITSYSSFAFHKVSVAIYNISNPKTVDPAKFPTRYCYCLSNRTNDLSDFTALLVDVVGNSTSYLTEIFKSTSILSVSQTNESDCVFICVMVGKSGRNLSDFWEMVEKSPVINYTFTSGVSSALATTRGTVRTSRLTTQSQHSLLRSYTTRWTTQWVSALKTFPWTKTTTPSEKEVTENEQMFPELPVESIGTRSSVPTSRNMTRTPWVTRRSTQAPTVLSGSMSVPLTVDDSTPGGPPSTSASTEDAQELSSTESQLHPTGILTTPSRLAQPSIVSGTLMPGTQTTNPTKAPAPRVPQTDGIPAGWPITPEKEPARVPATHHVSNCPRPLPKEEAITDTPLPLTMKKLNPCLMELCRFFQQCLCSVRKRDFSSEATRYCVEYYSWFLKNATLICQKIKRVSHSQTLKQKCLENVCRSV", "length": 538, "header": "tr|A0A0G2KAB0-1|A0A0G2KAB0_RAT Isoform 1 of HERV-H LTR-associating 1 OS=Rattus norvegicus OX=10116 GN=Hhla1 PE=4 SV=2 CANONICAL=A0A0G2KAB0-1" }, "isoforms": [ { "isoform_ac": "A0A0G2KAB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KAB0/entry#A0A0G2KAB0-1", "sequence": { "sequence": "MLSFPLHGPPMRLCMGLAYILSLWNAVSGLKGEGKKDKELALLPAAVSGNEGLKNEKYGSFLHTAESAFREKKTVKGVEVLATTELPARSVDLSALNLTELVNGMLSRALKDSKQFFSVLSITSYSSFAFHKVSVAIYNISNPKTVDPAKFPTRYCYCLSNRTNDLSDFTALLVDVVGNSTSYLTEIFKSTSILSVSQTNESDCVFICVMVGKSGRNLSDFWEMVEKSPVINYTFTSGVSSALATTRGTVRTSRLTTQSQHSLLRSYTTRWTTQWVSALKTFPWTKTTTPSEKEVTENEQMFPELPVESIGTRSSVPTSRNMTRTPWVTRRSTQAPTVLSGSMSVPLTVDDSTPGGPPSTSASTEDAQELSSTESQLHPTGILTTPSRLAQPSIVSGTLMPGTQTTNPTKAPAPRVPQTDGIPAGWPITPEKEPARVPATHHVSNCPRPLPKEEAITDTPLPLTMKKLNPCLMELCRFFQQCLCSVRKRDFSSEATRYCVEYYSWFLKNATLICQKIKRVSHSQTLKQKCLENVCRSV", "length": 538, "header": "tr|A0A0G2KAB0-1|A0A0G2KAB0_RAT Isoform 1 of HERV-H LTR-associating 1 OS=Rattus norvegicus OX=10116 GN=Hhla1 PE=4 SV=2 CANONICAL=A0A0G2KAB0-1" }, "locus": { "chromosome": "7", "start_pos": 97711308, "end_pos": 97674541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000083517.2", "url": "https://www.ensembl.org/id/ENSRNOT00000083517.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000075330.2", "url": "https://www.ensembl.org/id/ENSRNOP00000075330.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 353, "start_aa": "T", "end_pos": 353, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr353", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y4E8-1", "protein_name": "HERV-H LTR-associating 1", "gene_name": "HHLA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMRWLYWHIPAKLSLGFLCLFLVWNIASCVRRENKREKQAAVLATAELPAKSVDLAAVNLTELVNGMLSTALRGTKKLFSLLSVTSYSSFAFHKVSVTIYNISSLKNIDPGKFPMHYCYCLNNVTNDLTDFTALLVDIIGNSTSYLTEIFKSTSILSVRQSNDSDCIYICVMTGQTGRNLSDFWEMLEKSPVINYTFSSNTSSDLDLDSVFSSFMKSQEDSNKTVDPSAEHPWTFKSTSTPLALKGEDSPNTRPPPWTKMVSVKTSGFPTLHVDTSRPRGTAGAPPAAEGTLVTSAVLQPSPVADANMFWVQTLPPQDANNQIQTEQDLPSSVLSTPPYRPGLILKLHSAARCPHAILKDPYMTSPPVTIMLQKINPCLMELCRFFQLCLCVGQRRHSIKDAMRYCVEYYSWFLKNASYVCERVKRVAYSHTLKQKCLKNICKSV", "length": 445 }, "evidence": [ { "id": "A0A0G2KAB0", "url": "https://omabrowser.org/oma/group/A0A0G2KAB0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "C9JL84-1", "protein_name": "HERV-H LTR-associating protein 1", "gene_name": "HHLA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGFLSRGPSMKLCMGLACVLSLWNTVSGIKGEAKKEKGMTFLPTTVSGLREEERKEKGVAFLATTELPARSIDLSALNLTELVNGMLSRALKDSKKFFSLLSVTSYSSFAFHKFSVAVYNISNLKTVDPAKFPTRYCYCLNNRTNDLSDFTALLVDIIGNSTSYLTEIFKSTSILSVNQSNESDCIFICVMTGKSGRNLSDFWEIEEKYPIINYTFTSGLSGVLGAATRGTARTSKPTTKSQKTLPSTSPGHWTQSTPWASALRSSPWTETAAPSETEETLNTGRPPELPARATATWFSASHTLPALATRRVARTQWLTADRQTWASISSVPWAQTISEKKPGGSLWETRSSPPTTAGTEEAMNTTSLLAPAAEIMATPGSPSQASPTLGAFTHGTQTPSPTKATAPRYPQTGDLSAEWPFTAGEEPVLVPRPHQVSRCPQPLFKVGAMAAAPLTLAIQRLNPCLMELCQFFQQCLCMSQRSPRTEDMRYCLEYYSWFLKNATYICQRVKRVSHSHTLKQKCLENICKSV", "length": 531 }, "evidence": [ { "id": "A0A0G2KAB0", "url": "https://omabrowser.org/oma/group/A0A0G2KAB0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "G3N1Y4-1", "protein_name": "HHLA1 neighbor of OC90", "gene_name": "HHLA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPGFLLRGPLVRLCLDLTCVLSLFNTVSSFRGEAEKENVMTFLPTTVSSLREEERREKGIVFLDTTELPARSVDLSALNLTELVNGMLNRALKDSKNFFSLLSVTSYSSFAFHKFSVAIYNISNLKTVDPANFPTRYCYCLNNQTNDLSDFTALLVDIIGNSSSHLTEMFKSASILSVSQTNESDCIFICMMTGKSGRNLSDFWELVEKSPVINYTFTSNISGVLGAATTASALTSQLTPTSQQTLPRTSPPRGAQRAGVSALRTSSGTDTTPPSEAEQTLKTNVLPECPARATATLDMPSPTLPASTTRKVARTPRVTAHRQAQASTLPTPWAQVTSEKTPGGPPWETLASLPTSPKAEETMNTRSLSQPPAGTAAAVGSPIQTSPTSGPSTPGTQTPSPTKAPAPKYPQAGDLPAVWTFIPGEESALIPGTHQFSRCPEPLPKEGAMTAAPLALTVQKLNPCLMELCRFFQQCLCTSQKSEPRMEAGRYCLDYYSWFLKNATYICQRVKRVFHSHTLKQKCLENICKSV", "length": 531 }, "evidence": [ { "id": "A0A0G2KAB0", "url": "https://omabrowser.org/oma/group/A0A0G2KAB0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TYV2-1", "protein_name": "HERV-H LTR-associating protein 1 homolog", "gene_name": "Hhla1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQSFLLHCPPIRLCMGLACILFLWNAVSGLKGEGKKDKEMALPPATVSGNEGLKKEKNGSFLHAAESVFKEKKMVKGLEVLATTELPARSVDLSTLNLTELVNGMLNRALKDSKQFFSVLSITSYSSFAFHKVSVAIYNISNPKTVDPAKFPTRHCYCLSNRTNDLSDFTALLVDIVGNSTSYLTEIFKSTSILSVTQTNESDCVFICVMVGKSGRNLSDFWEMVEKSPVINYTFTSGVSSVLATTRGTARTSRLTTQSQQSLLRPYSVRWSTQWVSALKSLPWTKTSAPSEKELAESKQMFPELPVGTIGTHSSAPSSSNMTRTPWGTNRYTQAPTVPMPMPLSVDDSTPEGPPWASLPSTSASIEDAQQLRSTGNLLHPTGILTTPSRLAQPSRASGTLMPGTQTTNPTQAPAPRVPQTDGIPAEWPFIPEKEPARDPAAHQVSKCPRPLLQEEAITDTPLPLAMKKLTPCLMELCRFFQQCLCAIQKRDFSSEAISNCYLPEKIRKLITLH", "length": 514 }, "evidence": [ { "id": "A0A0G2KAB0", "url": "https://omabrowser.org/oma/group/A0A0G2KAB0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A0G2KAB0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 538, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0G2KAB0-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 353 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 509, "end_pos": 511 }, { "start_pos": 97, "end_pos": 99 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }