{
    "uniprot_canonical_ac": "A0A0G2K889-1",
    "uniprot_ac": "A0A0G2K889",
    "uniprot_id": "A0A0G2K889_RAT",
    "mass": {
        "chemical_mass": 142764.0,
        "monoisotopic_mass": 142764.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Ehmt1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K889",
            "id": "A0A0G2K889"
        }
    ],
    "protein_names": [
        {
            "name": "Euchromatic histone lysine methyltransferase 1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K889/entry#names_and_taxonomy",
            "id": "A0A0G2K889"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0060352",
            "recommended_name": {
                "id": "DOID:0060352",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060352",
                "name": "Kleefstra syndrome 1",
                "description": "A Kleefstra syndrome that is characterized by severe mental retardation, hypotonia, microcephaly, epileptic seizures, flat face with hypertelorism, synophrys, anteverted nares, everted lower lip, carp mouth with macroglossia, and heart defects and that has_material_basis_in a microdeletion in the chromosome region 9q34.3 or by a point mutation in the EHMT1 gene located in that region."
            },
            "synonyms": [
                {
                    "id": "DOID:0060352",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060352",
                    "name": "9q subtelomeric deletion syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0060352",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060352",
                    "name": "9q-syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0060352",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060352",
                    "name": "9q34 deletion syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "Kleefstra syndrome 1",
                    "description": "An autosomal dominant non-syndromic intellectual disability that has material basis in an autosomal dominant mutation of EHMT1 on chromosome 9q34.3."
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "9q-syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "KLEFS1",
                    "description": ""
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "Kleefstra syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "chromosome 9q34.3 deletion syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "Kleefstra syndrome 1",
                    "description": ""
                },
                {
                    "id": "MIM:610253",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/610253",
                    "name": "Kleefstra syndrome 1",
                    "description": "Kleefstra syndrome 1"
                }
            ],
            "evidence": [
                {
                    "id": "0060352",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060352"
                }
            ]
        },
        {
            "disease_id": "DOID:0080597",
            "recommended_name": {
                "id": "DOID:0080597",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080597",
                "name": "Kleefstra syndrome",
                "description": "A syndrome that is characterized by developmental delay and intellectual disability, severely limited or absent speech, and weak muscle tone."
            },
            "synonyms": [
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "Kleefstra syndrome 1",
                    "description": "An autosomal dominant non-syndromic intellectual disability that has material basis in an autosomal dominant mutation of EHMT1 on chromosome 9q34.3."
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "9q-syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "KLEFS1",
                    "description": ""
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "Kleefstra syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "chromosome 9q34.3 deletion syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0027407",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0027407",
                    "name": "Kleefstra syndrome 1",
                    "description": ""
                },
                {
                    "id": "MIM:610253",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/610253",
                    "name": "Kleefstra syndrome 1",
                    "description": "Kleefstra syndrome 1"
                }
            ],
            "evidence": [
                {
                    "id": "0080597",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080597"
                }
            ]
        },
        {
            "disease_id": "DOID:3748",
            "recommended_name": {
                "id": "DOID:3748",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3748",
                "name": "esophagus squamous cell carcinoma",
                "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus."
            },
            "synonyms": [
                {
                    "id": "DOID:3748",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3748",
                    "name": "SCC of esophagus",
                    "description": ""
                },
                {
                    "id": "DOID:3748",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3748",
                    "name": "SCC of oesophagus",
                    "description": ""
                },
                {
                    "id": "DOID:3748",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3748",
                    "name": "oesophagus squamous cell carcinoma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "3748",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3748"
                }
            ]
        },
        {
            "disease_id": "DOID:934",
            "recommended_name": {
                "id": "DOID:934",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:934",
                "name": "viral infectious disease",
                "description": "A disease by infectious agent that results in infection, has_material_basis_in Viruses."
            },
            "synonyms": [
                {
                    "id": "DOID:934",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:934",
                    "name": "Viral Infection",
                    "description": ""
                },
                {
                    "id": "DOID:934",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:934",
                    "name": "Viral disease",
                    "description": ""
                },
                {
                    "id": "DOID:934",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:934",
                    "name": "virus infection",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "934",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:934"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
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            ],
            "common_name": "Rat",
            "glygen_name": "Rat",
            "reference_species": "Rattus norvegicus [10116]"
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            "id": "1307588",
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        {
            "id": "A0A0G2K889",
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        {
            "id": "A0A0G2K889-1",
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        },
        {
            "id": "A0A8I6AB09",
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        },
        {
            "id": "A0A8I6AB09-1",
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            "id": "A0A8I6ABS0",
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        },
        {
            "id": "A0A8I6ABS0-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6ABS0-1",
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        },
        {
            "id": "A0A8I6ANQ0",
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        },
        {
            "id": "A0A8I6ANQ0-1",
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        {
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            "categories": [
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        "length": 1302,
        "header": "tr|A0A0G2K889-1|A0A0G2K889_RAT Isoform 1 of Euchromatic histone lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Ehmt1 PE=1 SV=2 CANONICAL=A0A0G2K889-1"
    },
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                "length": 1302,
                "header": "tr|A0A0G2K889-1|A0A0G2K889_RAT Isoform 1 of Euchromatic histone lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Ehmt1 PE=1 SV=2 CANONICAL=A0A0G2K889-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 7728969,
                "end_pos": 7581795,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000086843.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000086843.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000074513.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000074513.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AB09-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K889/entry#A0A8I6AB09-1",
            "sequence": {
                "sequence": "MLIAIVFCFLPLQQAVLAKQETKQDCCMKTELLREDTLMAADEGSTEKQAGETPMAADGETNGSCEKSGDISHPNAPKHTQENTRASPQEGTNRVSRVAENGVSERDTEVGKQNHVTADDFMQTSVIGSNGYFLNKPALQGQPLRTPNTLNSSLPGHAAKTLPGGASKCRTPSALPQTPTTAPTVPGEGSADTEDRKPTASGTDVRVHRARKTMPKSILGLHAASKDHREVQDHKEPKEDINRNISECGRQQLLPTFPALHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGAKGEKVLDDSALHVNGESLEMDSEEEDSEELEDEEDRGAEQAAAFPTEDSRTSKESMSETDRAAKMDGDSEEEQESPDTGEDEDGGDESDLSSESSIKKKFLKRRGKTDSPWIKPARKRRRRSRKKPSSMLGSEACKSSPGSMEQAALGDSAGYMEVSLDSLDLRVRGILSSQTENEGLANGPDVLETDGLHEVPLCSCRMETPKSREISTLANNQCMATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQPESSISHRFHKDCASRVNNASYCPHCGEETSKAKEVTIAKADTTSTVTLAPGQEKSLAAEGRADTTTGSIAGAPEDEKSQSTVTQAPECFDPAGPAGFVRPTSGFSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQSKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLDAVKYLIKAGAQVDPKDAEGSTCLHLAAKKGHYDVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDKPVAVEKTVSRDIARGYERIPIPCVNAVDSELCPTNYKYVSQNCVTSPMNIDRNITHLQYCVCVDDCSSSTCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTQDMGWGVRSLQDIPLGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMSHQDLRFPRIAFFSTRLIQAGEQLGFDYGERFWDVKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQENGLPDTSSAAAADPL",
                "length": 1302,
                "header": "tr|A0A8I6AB09-1|A0A8I6AB09_RAT Computationally mapped isoform of Euchromatic histone lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Ehmt1 PE=1 SV=1 CANONICAL=A0A0G2K889-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 7673132,
                "end_pos": 7581795,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000108139.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000108139.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000090039.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000090039.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6ABS0-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K889/entry#A0A8I6ABS0-1",
            "sequence": {
                "sequence": "MAAADAEQAVLAKQETKQDCCMKTELLREDTLMAADEGSTEKQAGETPMAADGETNGSCEKSGDISHPNAPKHTQENTRASPQEGTNRVSRVAENGVSERDTEVGKQNHVTADDFMQTSVIGSNGYFLNKPALQGQPLRTPNTLNSSLPGHAAKTLPGGASKCRTPSALPQTPTTAPTVPGEGSADTEDRKPTASGTDVRVHRARKTMPKSILGLHAASKDHREVQDHKEPKEDINRNISECGRQQLLPTFPALHQSLPQNQCYMATTKSQTAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGAKGEKVLDDSALHVNGESLEMDSEEEDSEELEDEEDRGAEQAAAFPTEDSRTSKESMSETDRAAKMDGDSEEEQESPDTGEDEDGGDESDLSSESSIKKKFLKRRGKTDSPWIKPARKRRRRSRKKPSSMLGLANGPDVLETDGLHEVPLCSCRMETPKSREISTLANNQCMATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQPESSISHRFHKDCASRVNNASYCPHCGEETSKAKEVTIAKADTTSTVTLAPGQEKSLAAEGRADTTTGSIAGAPEDEKSQSTVTQAPECFDPAGPAGFVRPTSGFSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQSKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLDAVKYLIKAGAQVDPKDAEGSTCLHLAAKKGHYDVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDKPVAVEKTVSRDIARGYERIPIPCVNAVDSELCPTNYKYVSQNCVTSPMNIDRNITHLQYCVCVDDCSSSTCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTQDMGWGVRSLQDIPLGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMSHQDLRFPRIAFFSTRLIQAGEQLGFDYGERFWDVKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQENGLPDTSSAAAADPL",
                "length": 1243,
                "header": "tr|A0A8I6ABS0-1|A0A0G2K889_RAT Computationally mapped isoform of Euchromatic histone lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Ehmt1 PE=1 SV=1 CANONICAL=A0A0G2K889-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 7728927,
                "end_pos": 7581795,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000101650.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000101650.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000089453.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000089453.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6ANQ0-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K889/entry#A0A8I6ANQ0-1",
            "sequence": {
                "sequence": "MLIAIVFCFLPLQQAVLAKQETKQDCCMKTELLREDTLMAADEGSTEKQAGETPMAADGETNGSCEKSGDISHPNAPKHTQENTRASPQEGTNRVSRVAENGVSERDTEVGKQNHVTADDFMQTSVIGSNGYFLNKPALQGQPLRTPNTLNSSLPGHAAKTLPGGASKCRTPSALPQTPTTAPTVPGEGSADTEDRKPTASGTDVRVHRARKTMPKSILGLHAASKDHREVQDHKEPKEDINRNISECGRQQLLPTFPALHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGAKGEKVLDDSALHVNGESLEMDSEEEDSEELEDEEDRGAEQAAAFPTEDSRTSKESMSETDRAAKSSESSIKKKFLKRRGKTDSPWIKPARKRRRRSRKKPSSMLGSEACKSSPGSMEQAALGDSAGYMEVSLDSLDLRVRGILSSQTENEGLANGPDVLETDGLHEVPLCSCRMETPKSREISTLANNQCMATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQPESSISHRFHKDCASRVNNASYCPHCGEETSKAKEVTIAKADTTSTVTLAPGQEKSLAAEGRADTTTGSIAGAPEDEKSQSTVTQAPECFDPAGPAGFVRPTSGFSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQSKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLDAVKYLIKAGAQVDPKDAEGSTCLHLAAKKGHYDVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDKPVAVEKTVSRDIARGYERIPIPCVNAVDSELCPTNYKYVSQNCVTSPMNIDRNITHLQYCVCVDDCSSSTCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTQDMGWGVRSLQDIPLGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMSHQDLRFPRIAFFSTRLIQAGEQLGFDYGERFWDVKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQENGLPDTSSAAAADPL",
                "length": 1276,
                "header": "tr|A0A8I6ANQ0-1|A0A8I6ANQ0_RAT Computationally mapped isoform of Euchromatic histone lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Ehmt1 PE=1 SV=1 CANONICAL=A0A0G2K889-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 7673132,
                "end_pos": 7581795,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000104449.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000104449.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000097763.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000097763.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D4A005-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K889/entry#D4A005-1",
            "sequence": {
                "sequence": "MSAQAVLAKQETKQDCCMKTELLREDTLMAADEGSTEKQAGETPMAADGETNGSCEKSGDISHPNAPKHTQENTRASPQEGTNRVSRVAENGVSERDTEVGKQNHVTADDFMQTSVIGSNGYFLNKPALQGQPLRTPNTLNSSLPGHAAKTLPGGASKCRTPSALPQTPTTAPTVPGEGSADTEDRKPTASGTDVRVHRARKTMPKSILGLHAASKDHREVQDHKEPKEDINRNISECGRQQLLPTFPALHQSLPQNQCYMATTKSQTAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGAKGEKVLDDSALHVNGESLEMDSEEEDSEELEDEEDRGAEQAAAFPTEDSRTSKESMSETDRAAKMDGDSEEEQESPDTGEDEDGGDESDLSSESSIKKKFLKRRGKTDSPWIKPARKRRRRSRKKPSSMLGSEACKSSPGSMEQAALGDSAGYMEVSLDSLDLRVRGILSSQTENEGLANGPDVLETDGLHEVPLCSCRMETPKSREISTLANNQCMATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQPESSISHRFHKDCASRVNNASYCPHCGEETSKAKEVTIAKADTTSTVTLAPGQEKSLAAEGRADTTTGSIAGAPEDEKSQSTVTQAPECFDPAGPAGFVRPTSGFSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQSKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLDAVKYLIKAGAQVDPKDAEGSTCLHLAAKKGHYDVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDKPVAVEKTVSRDIARGYERIPIPCVNAVDSELCPTNYKYVSQNCVTSPMNIDRNITHLQYCVCVDDCSSSTCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTQDMGWGVRSLQDIPLGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMSHQDLRFPRIAFFSTRLIQAGEQLGFDYGERFWDVKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQENGLPDTSSAAAADPL",
                "length": 1285,
                "header": "tr|D4A005-1|D4A005_RAT Computationally mapped isoform of Euchromatic histone lysine methyltransferase 1  OS=Rattus norvegicus OX=10116 GN=Ehmt1 PE=1 SV=4 CANONICAL=A0A0G2K889-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 7673289,
                "end_pos": 7581795,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000066777.4",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000066777.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000063511.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000063511.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "R-RNO-2559582",
            "name": "Senescence-Associated Secretory Phenotype (SASP)",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2559582",
            "resource": "Reactome",
            "description": "Senescence-Associated Secretory Phenotype (SASP)"
        },
        {
            "id": "R-RNO-3214841",
            "name": "PKMTs methylate histone lysines",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3214841",
            "resource": "Reactome",
            "description": "PKMTs methylate histone lysines"
        },
        {
            "id": "R-RNO-6804760",
            "name": "Regulation of TP53 Activity through Methylation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6804760",
            "resource": "Reactome",
            "description": "Regulation of TP53 Activity through Methylation"
        },
        {
            "id": "R-RNO-8953750",
            "name": "Transcriptional Regulation by E2F6",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8953750",
            "resource": "Reactome",
            "description": "Transcriptional Regulation by E2F6"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A3Q1LPD0-1",
            "protein_name": "Euchromatic histone lysine methyltransferase 1",
            "gene_name": "EHMT1",
            "tax_id": 9913,
            "organism": "Bos taurus",
            "sequence": {
                "sequence": "MARGRGGATLRARAMAAADAEAVPAKGETKQDCGLGAELPSEGSPMAADDGSAEQQGGEAPVAADGETNGSCDQSDASGHAAAVKHPQESTRGSPQEGAGPGSRIAENGILDRDPEVGKQNHIRSDGFPQNPVIGSNGYFLGKAPLSEPPLRVASALASSLPGHAAKTLPGGAGKGRTPGAFPQPPAAVPAKPGEGSKDTEDKKAPAPGADVKVHRARKTMPKSIPGLHAASKDPREGRDARDHEEPKEELSRGASEFARQQLSPPFPSLHQSLPQNQCYVATAKAQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTGGSKGEKDLSDGSLHVNGESLDLDSEEDDSEELDEDEDQGGPPAAAFPTEDGRASKDGVLAPDCSQKVDGESEEEQESAGTADEEEDGDESDLSSESSVKKKFLKRKGKPDSPWIKPARKRRRRSKKKPCSVLGLANGPDAGETDGLQEVPLCSCRMETPKSREITTLANNQCMATESVDHQLGRCTNSVVKHELMRPSSKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQPESSISHRFHKACASRVNNASYCPHCGEETSKAKEVTIAKADTTSTVTLAPGQEKSCAAEGRADTTTGSAAGPLLSEEDKPQSLAPQVPEGFDPTGPAGLGKPAPGLSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLIQAGANIDTCSEDQRTPLMEAAENNHLDAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYDVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAARCDLHAVNIHGDSPLHIAAREDRYACVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQVSQALRDAAPDRPTPVEKTVSRDIARGYERIPIPCVNGVDGEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLLFECNHACSCWRTCRNRVVQNGLRARLQLYRTQNMGWGVRSLQDIPLGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGELYCIDARFYGNVSRFINHHCEPNLVPVRVFMSHQDLRFPRIAFFSTRLIEAGEQLGASGTSRASCSAAAAAPPSAGTPGPRWPSGRPVPRRTGCPTPAPRLPTRYESAARRPSGRRSLWFGEDAEACRRPAGLPRAAGAGPGCAGTPGLLAGLAVSSRRRSFCSTFLVSPRVSSLPAHRRAGGCVLSARTLRVARRGPHGRCWLWAAQTPCPPPLRGQGRATADFGENVGLLFKEILYLVLYTRPLTCFFPRMRFGAQDGHGPGAPHVLLISKPHAMMMNKLVYFLPLLDIRTNKK",
                "length": 1449
            },
            "evidence": [
                {
                    "id": "A0A0G2K889",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K889/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Bovine",
            "common_name": "Bovine"
        },
        {
            "uniprot_canonical_ac": "Q5DW34-1",
            "protein_name": "Histone-lysine N-methyltransferase EHMT1",
            "gene_name": "Ehmt1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MAAADAEQAVLAKQETKQDCCMKTELLREDTPMAADEGSTEKQEGETPMAADGETNGSCEKSGDPSHLNAPKHTQENTRASPQEGTNRVSRVAENGVSERDTEVGKQNHVTADDFMQTSVIGSNGYFLNKPALQGQPLRTPNILTSSLPGHAAKTLPGGASKCRTLSALPQTPTTAPTVPGEGSADTEDRKPTASGTDVRVHRARKTMPKSILGLHAASKDHREVQDHKEPKEDINRNISECGRQQLLPTFPALHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGAKGEKALDDSALHVNGESLEMDSEDEDSDELEDDEDHGAEQAAAFPTEDSRTSKESMSETDRAAKMDGDSEEEQESPDTGEDEDGGDESDLSSESSIKKKFLKRRGKTDSPWIKPARKRRRRSRKKPSSMLGSEACKSSPGSMEQAALGDSAGYMEVSLDSLDLRVRGILSSQTENEGLASGPDVLGTDGLQEVPLCSCRMETPKSREISTLANNQCMATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQPESSISHRFHKDCASRVNNASYCPHCGEEASKAKEVTIAKADTTSTVTLAPGQEKSLAAEGRADTTTGSIAGAPEDERSQSTAPQAPECFDPAGPAGLVRPTSGLSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQSKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLDAVKYLIKAGAQVDPKDAEGSTCLHLAAKKGHYDVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVELVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLSSQVWSALQMSKALRDSAPDKPVAVEKTVSRDIARGYERIPIPCVNAVDSELCPTNYKYVSQNCVTSPMNIDRNITHLQYCVCVDDCSSSTCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTQDMGWGVRSLQDIPLGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMSHQDLRFPRIAFFSTRLIQAGEQLGFDYGERFWDVKGKLFSCRCGSSKCRHSSAALAQRQASAAQEPQENGLPDTSSAAAADPL",
                "length": 1296
            },
            "evidence": [
                {
                    "id": "A0A0G2K889",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K889/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9H9B1-1",
            "protein_name": "Histone-lysine N-methyltransferase EHMT1",
            "gene_name": "EHMT1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAAADAEAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLGEGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYMEVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQEVPLCSCRMETPKSREITTLANNQCMATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQPESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKADTTSTVTPVPGQEKGSALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPAGLGRPTPGLSQGPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQEDGLPDTSSAAAADPL",
                "length": 1298
            },
            "evidence": [
                {
                    "id": "A0A0G2K889",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K889/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "negative regulation of transcription by RNA polymerase II",
                        "id": "GO:0000122",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K889",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K889"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of DNA-templated transcription",
                        "id": "GO:0045892",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K889",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K889"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chromatin organization",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325",
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                    {
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                    {
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                    {
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                        "pmid": ""
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                        "pmid": ""
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                    {
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                                "database": "UniProtKB",
                                "id": "A0A0G2K889",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K889"
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                        "pmid": ""
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                    {
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                                "id": "A0A0G2K889",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K889"
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                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein-lysine N-methyltransferase activity",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K889",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K889"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone H3K9 methyltransferase activity",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K889",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K889"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone H3K27 methyltransferase activity",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046976",
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                                "database": "UniProtKB",
                                "id": "A0A0G2K889",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K889"
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                        "pmid": ""
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                    {
                        "name": "transcription corepressor binding",
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                                "database": "UniProtKB",
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                        "pmid": ""
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