{ "uniprot_canonical_ac": "A0A0G2K679-1", "uniprot_ac": "A0A0G2K679", "uniprot_id": "A0A0G2K679_RAT", "mass": { "chemical_mass": 100470.0, "monoisotopic_mass": 100470.0 }, "refseq": {}, "gene_names": [ { "name": "Gtf3c2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2K679", "id": "A0A0G2K679" } ], "protein_names": [ { "name": "General transcription factor IIIC subunit 2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K679/entry#names_and_taxonomy", "id": "A0A0G2K679" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K679", "url": "https://www.uniprot.org/uniprot/A0A0G2K679" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Gtf3c2", "url": "https://www.uniprot.org/uniprot/A0A0G2K679", "locus": { "chromosome": "6", "start_pos": 25220490, "end_pos": 25197268, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000056904", "url": "https://www.ensembl.org/id/ENSRNOG00000056904" } ] } } ], "crossref": [ { "id": "A0A0G2K679", "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2K679", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSRNOG00000056904", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000056904", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "313914", "url": "https://www.ncbi.nlm.nih.gov/gene/313914", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:313914", "url": "https://www.genome.jp/dbget-bin/www_bget?rno:313914", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DKGFIWQ", "url": "https://omabrowser.org/oma/group/DKGFIWQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5PQP7", "url": "https://www.orthodb.org/?gene=Q5PQP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15052:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15052:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-76061", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-76066", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "1560392", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1560392", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2K679", "url": "https://www.uniprot.org/uniprot/A0A0G2K679", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K679-1", "url": "https://www.uniprot.org/uniprot/A0A0G2K679-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A405", "url": "https://www.uniprot.org/uniprot/A0A8I6A405", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A405-1", "url": "https://www.uniprot.org/uniprot/A0A8I6A405-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5PQP7", "url": "https://www.uniprot.org/uniprot/Q5PQP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5PQP7-1", "url": "https://www.uniprot.org/uniprot/Q5PQP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTCGVGYVALGEADPVGSMIVVDSPGQEELNQLDVKASSETSSVEASIEMSLPPPLPGFEDSSDKRRLPPDQESLTRLEQQDLSSEMAKVSNPRASKPSGRRGGRTPRGAKRPQQRKPPSAPLVPGLLDQSNPLSTPMPKKRSQKSKGDLLLLKLSKGLDQPESPHPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPLSGPKSPKVSSPTKPKKTRQAASQGEEDGRARDEDFVLQVEGEDEEESEAPSENSSDPEPVAPRSTPRGPAAGKQKPHCRGMAPNGLPNYIMAPVWKCLHLTKDLREQQHSFWEFAEWIPVAWKWQLLSELEAAPYLPQEEKSPLFSVQREGIPEDGTIYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDSGCIWDLKFCPSGAWEHPETLRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAMKPAIYKVQCLATLQVGSVQASDPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTIQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINCIKRFLSTELSWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTVAAGDISGELIAAILPDMASNPINVKKPAERRFPIYKADLIPYQDSPEDQDYSSTSSETPNPPKARTYTETINHHYLLFQDTDLSSFHNLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLTSPLAHRVQLESRANFNAMFQPSFPTEGPGFSPSSHCLLPNP", "length": 908, "header": "tr|A0A0G2K679-1|A0A0G2K679_RAT Isoform 1 of General transcription factor IIIC subunit 2 OS=Rattus norvegicus OX=10116 GN=Gtf3c2 PE=1 SV=2 CANONICAL=A0A0G2K679-1" }, "isoforms": [ { "isoform_ac": "A0A0G2K679-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K679/entry#A0A0G2K679-1", "sequence": { "sequence": "MDTCGVGYVALGEADPVGSMIVVDSPGQEELNQLDVKASSETSSVEASIEMSLPPPLPGFEDSSDKRRLPPDQESLTRLEQQDLSSEMAKVSNPRASKPSGRRGGRTPRGAKRPQQRKPPSAPLVPGLLDQSNPLSTPMPKKRSQKSKGDLLLLKLSKGLDQPESPHPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPLSGPKSPKVSSPTKPKKTRQAASQGEEDGRARDEDFVLQVEGEDEEESEAPSENSSDPEPVAPRSTPRGPAAGKQKPHCRGMAPNGLPNYIMAPVWKCLHLTKDLREQQHSFWEFAEWIPVAWKWQLLSELEAAPYLPQEEKSPLFSVQREGIPEDGTIYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDSGCIWDLKFCPSGAWEHPETLRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAMKPAIYKVQCLATLQVGSVQASDPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTIQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINCIKRFLSTELSWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTVAAGDISGELIAAILPDMASNPINVKKPAERRFPIYKADLIPYQDSPEDQDYSSTSSETPNPPKARTYTETINHHYLLFQDTDLSSFHNLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLTSPLAHRVQLESRANFNAMFQPSFPTEGPGFSPSSHCLLPNP", "length": 908, "header": "tr|A0A0G2K679-1|A0A0G2K679_RAT Isoform 1 of General transcription factor IIIC subunit 2 OS=Rattus norvegicus OX=10116 GN=Gtf3c2 PE=1 SV=2 CANONICAL=A0A0G2K679-1" }, "locus": { "chromosome": "6", "start_pos": 25219762, "end_pos": 25203161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000079292.2", "url": "https://www.ensembl.org/id/ENSRNOT00000079292.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000073708.2", "url": "https://www.ensembl.org/id/ENSRNOP00000073708.2" } ] } }, { "isoform_ac": "A0A8I6A405-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K679/entry#A0A8I6A405-1", "sequence": { "sequence": "MDTCGVGYVALGEADPVGSMIVVDSPGQEELNQLDVKASSETSSVEASIEMSLPPPLPGFEDSSDKRRLPPDQESLTRLEQQDLSSEMAKVSNPRASKPSGRRGGRTPRGAKRPQQRKPPSAPLVPGLLDQSNPLSTPMPKKRSQKSKGDLLLLKLSKGLDQPESPHPKRPPEDFETPSGERPRRRAAQVVSLPNPGWPRTCDPPNSASRVLGLQACATTPGSPSHFSQTSPRALLYLQELAEELSTALPAPLSGPKSPKVSSPTKPKKTRQAASQGEEDGRARDEDFVLQVEGEDEEESEAPSENSSDPEPVAPRSTPRGPAAGKQKPHCRGMAPNGLPNYIMAPVWKCLHLTKDLREQQHSFWEFAEWIPVAWKWQLLSELEAAPYLPQEEKSPLFSVQREGIPEDGTIYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDSGCIWDLKFCPSGAWEHPETLRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPGKLHSCHGSSQSSQCLATLQVGSVQASDPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTIQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINCIKRFLSTELSWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTVAAGDISGELIAAILPDMASNPINVKKPAERRFPIYKADLIPYQDSPEDQDYSSTSSETPNPPKARTYTETINHHYLLFQDTDLSSFHNLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLTSPLAHRVQLESRANFNAMFQPSFPTEGPGFSPSSHCLLPNP", "length": 954, "header": "tr|A0A8I6A405-1|A0A0G2K679_RAT Computationally mapped isoform of General transcription factor IIIC subunit 2 OS=Rattus norvegicus OX=10116 GN=Gtf3c2 PE=1 SV=1 CANONICAL=A0A0G2K679-1" }, "locus": { "chromosome": "6", "start_pos": 25219762, "end_pos": 25203161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000116942.1", "url": "https://www.ensembl.org/id/ENSRNOT00000116942.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000087253.1", "url": "https://www.ensembl.org/id/ENSRNOP00000087253.1" } ] } }, { "isoform_ac": "Q5PQP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2K679/entry#Q5PQP7-1", "sequence": { "sequence": "MDTCGVGYVALGEADPVGSMIVVDSPGQEELNQLDVKASSETSSVEASIEMSLPPPLPGFEDSSDKRRLPPDQESLTRLEQQDLSSEMAKVSNPRASKPSGRRGGRTPRGAKRPQQRKPPSAPLVPGLLDQSNPLSTPMPKKRSQKSKGDLLLLKLSKGLDQPESPHPKRPPEDFETPSGERPRRRAAQVVSLPNPGWPRTCDPPNSASRVLGLQACATTPGSPSHFSQTSPRALLYLQELAEELSTALPAPLSGPKSPKVSSPTKPKKTRQAASQGEEDGRARDEDFVLQVEGEDEEESEAPSENSSDPEPVAPRSTPRGPAAGKQKPHCRGMAPNGLPNYIMAPVWKCLHLTKDLREQQHSFWEFAEWIPVAWKWQLLSELEAAPYLPQEEKSPLFSVQREGIPEDGTIYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDSGCIWDLKFCPSGAWEHPETLRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAMKPAIYKVQCLATLQVGSVQASDPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTIQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINCIKRFLSTELSWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTVAAGDISGELIAAILPDMASNPINVKKPAERRFPIYKADLIPYQDSPEDQDYSSTSSETPNPPKARTYTETINHHYLLFQDTDLSSFHNLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLTSPLAHRVQLESRANFNAMFQPSFPTEGPGFSPSSHCLLPNP", "length": 951, "header": "tr|Q5PQP7-1|A0A0G2K679_RAT Computationally mapped isoform of General transcription factor IIIC subunit 2 OS=Rattus norvegicus OX=10116 GN=Gtf3c2 PE=1 SV=1 CANONICAL=A0A0G2K679-1" }, "locus": { "chromosome": "6", "start_pos": 25219762, "end_pos": 25203161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000077481.2", "url": "https://www.ensembl.org/id/ENSRNOT00000077481.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000070546.2", "url": "https://www.ensembl.org/id/ENSRNOP00000070546.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 668, "start_aa": "T", "end_pos": 668, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr668", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [ { "start_pos": 165, "end_pos": 165, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q5PQP7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5PQP7" } ], "site_lbl": "Ser165" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K679", "url": "https://www.uniprot.org/uniprot/A0A0G2K679" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] } ], "pathway": [ { "id": "rno:313914", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?rno:313914", "resource": "KEGG Pathway" }, { "id": "R-RNO-76061", "name": "RNA Polymerase III Transcription Initiation From Type 1 Promoter", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-RNO-76066", "name": "RNA Polymerase III Transcription Initiation From Type 2 Promoter", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MEI8-1", "protein_name": "Ral transcription factor IIIC subunit 2", "gene_name": "GTF3C2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDTYGVGYMALEEAGPVGNMTVVDSPGQEVLNQLDVKASSETTSVEASIEMPLSTPFPGYEDSLDERRLLPEQESLSRLQQQDLSSEMSKVPKPRASKPGPKRGGRTRKGPKRPQQPNSPSAPRVPGLLDQSNPLSTPMPKKRGRKSKADLLLLKLSKGLDQPESPHPKMPPEDFETPPGERPRRRAAQVALLYLQELAEELSTALPTPVSCPEGPQVSSPTQPKIIQPQAACLRGEGDNTARDEDFVLQVEAEEAEESEAPSENSSDPEPAAPRSTTRGSTQKQKPHVRGMAHNGLPNHIMAPVWKCLHLTKDIRDQKHSYWEFAEWIPLAWKWRLLSELEAAPYLPQEEKSPLFSVQREGLPEDGTLYRINRFSSITAHPERLDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETHSLSQLYSGPGLLQLWDLGTLQQESCLGNRAHFVYGIACDHGCIWDLKFCPSGAWELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPLDAVKPAIYKVHCVATLQVGSMQASEPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVLWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTLQWCKANSHFLASAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTIAAGDISGELIAAILPDMALNPTNVKRPLDRRFPIYKADLIPYQDSPEGQDHTSASSGAPNPPKARTYAETVNHHYLLFQDTDLRSFHGLPHREPMLRMQEGEGQTRLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLTCPLGHRMQLESRAHFSAMFQLASPSPGPGFPPTSHCLLPGP", "length": 909 }, "evidence": [ { "id": "A0A0G2K679", "url": "https://omabrowser.org/oma/group/A0A0G2K679/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BL74-1", "protein_name": "General transcription factor 3C polypeptide 2", "gene_name": "Gtf3c2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTCGVGYVALGEADPVGSMIVVDSPGQEELSQLDVKASETSGVEASIEMSLPPPLPGFEDSSDRRLPPDQESLTRLEQQDLSSEMSKVSNTRASKPSGRRGGRTARGAKRPQQRKPPSTPLVPGLLDQSNPLSTPMPKKRSQKSKGDLLLLKLSKGLDQPESPHPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPPLSGPKSPKVSSPTKPKKTRQASSQGEEDGSARDEDFVLQVEGEDEEESEAPSENSSDPEPVAPRSTPRGPAAGKQKPHCRGMAPNGLPNYIMAPVWKCLHLTKDLREQHHSFWEFAEWIPVAWKWQLLSELEAAPYLPQEEKSPLFSVQREGIPEDGTIYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDSGCIWDLKFCPSGAWEHPETLRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAMKPAIYKVQCLATLQVGSVQASDPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTIQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINCIKRFLSTELSWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTVAAGDISGELIAAILPDMASNPINVKKPAERRFPIYKADLIPYQDSPEDQDYSSTSSETPNPPKARTYTETINHHYLLFQDTDLSSFHNLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLTSPLAHRVQLESRANFNAMFQPSFPTEGPGFSPSSHCLLPNP", "length": 907 }, "evidence": [ { "id": "47563335", "url": "http://www.informatics.jax.org/homology/47563335", "database": "MGI" }, { "id": "A0A0G2K679", "url": "https://omabrowser.org/oma/group/A0A0G2K679/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUA4-1", "protein_name": "General transcription factor 3C polypeptide 2", "gene_name": "GTF3C2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSVQREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGAWELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVATLQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTIAAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPNPPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGFSPTSHRLLPTP", "length": 911 }, "evidence": [ { "id": "47563335", "url": "http://www.informatics.jax.org/homology/47563335", "database": "MGI" }, { "id": "A0A0G2K679", "url": "https://omabrowser.org/oma/group/A0A0G2K679/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K679", "url": "https://www.uniprot.org/uniprot/A0A0G2K679" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K679", "url": "https://www.uniprot.org/uniprot/A0A0G2K679" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K679", "url": "https://www.uniprot.org/uniprot/A0A0G2K679" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K679", "url": "https://www.uniprot.org/uniprot/A0A0G2K679" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K679", "url": "https://www.uniprot.org/uniprot/A0A0G2K679" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K679", "url": "https://www.uniprot.org/uniprot/A0A0G2K679" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A0G2K679-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 908, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0G2K679-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 668 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 165 ], "sequon_annotation_sites": [ { 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