{
    "uniprot_canonical_ac": "A0A0G2K2P3-1",
    "uniprot_ac": "A0A0G2K2P3",
    "uniprot_id": "A0A0G2K2P3_RAT",
    "mass": {
        "chemical_mass": 22794.0,
        "monoisotopic_mass": 22794.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Tnfaip8",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3",
            "id": "A0A0G2K2P3"
        }
    ],
    "protein_names": [
        {
            "name": "Tumor necrosis factor alpha-induced protein 8",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2P3/entry#names_and_taxonomy",
            "id": "A0A0G2K2P3"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K2P3",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3"
                }
            ],
            "common_name": "Rat",
            "glygen_name": "Rat",
            "reference_species": "Rattus norvegicus [10116]"
        }
    ],
    "gene": [
        {
            "name": "Tnfaip8",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3",
            "locus": {
                "chromosome": "18",
                "start_pos": 43299517,
                "end_pos": 43183916,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000026136",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000026136"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "A0A0G2K2P3",
            "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2K2P3",
            "database": "AlphaFoldDB",
            "categories": []
        },
        {
            "id": "ENSRNOG00000026136",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000026136",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "307428",
            "url": "https://www.ncbi.nlm.nih.gov/gene/307428",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR008477",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008477",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR038355",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038355",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "YPDTMHS",
            "url": "https://omabrowser.org/oma/group/YPDTMHS/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A0G2K2P3",
            "url": "https://www.orthodb.org/?gene=A0A0G2K2P3",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "D4A9G3",
            "url": "https://www.orthodb.org/?gene=D4A9G3",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12757",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12757",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12757:SF3",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12757:SF3",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF05527",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05527",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-1483255",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1483255",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1305908",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305908",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2K2P3",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K2P3-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5Y0F2",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y0F2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5Y0F2-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5Y0F2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AJX1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AJX1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AJX1-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AJX1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A9G3",
            "url": "https://www.uniprot.org/uniprot/D4A9G3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A9G3-1",
            "url": "https://www.uniprot.org/uniprot/D4A9G3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSASRGEITSVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI",
        "length": 198,
        "header": "tr|A0A0G2K2P3-1|A0A0G2K2P3_RAT Isoform 1 of Tumor necrosis factor alpha-induced protein 8  OS=Rattus norvegicus OX=10116 GN=Tnfaip8 PE=3 SV=2 CANONICAL=A0A0G2K2P3-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K2P3-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2P3/entry#A0A0G2K2P3-1",
            "sequence": {
                "sequence": "MSASRGEITSVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI",
                "length": 198,
                "header": "tr|A0A0G2K2P3-1|A0A0G2K2P3_RAT Isoform 1 of Tumor necrosis factor alpha-induced protein 8  OS=Rattus norvegicus OX=10116 GN=Tnfaip8 PE=3 SV=2 CANONICAL=A0A0G2K2P3-1"
            },
            "locus": {
                "chromosome": "18",
                "start_pos": 43298409,
                "end_pos": 43224798,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000086431.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000086431.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000072322.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000072322.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5Y0F2-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2P3/entry#A0A8I5Y0F2-1",
            "sequence": {
                "sequence": "MATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI",
                "length": 188,
                "header": "tr|A0A8I5Y0F2-1|A0A0G2K2P3_RAT Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8  OS=Rattus norvegicus OX=10116 GN=Tnfaip8 PE=3 SV=1 CANONICAL=A0A0G2K2P3-1"
            },
            "locus": {
                "chromosome": "18",
                "start_pos": 43298409,
                "end_pos": 43184001,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000118975.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000118975.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000076830.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000076830.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AJX1-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2P3/entry#A0A8I6AJX1-1",
            "sequence": {
                "sequence": "MPKLVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI",
                "length": 192,
                "header": "tr|A0A8I6AJX1-1|A0A0G2K2P3_RAT Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8  OS=Rattus norvegicus OX=10116 GN=Tnfaip8 PE=3 SV=1 CANONICAL=A0A0G2K2P3-1"
            },
            "locus": {
                "chromosome": "18",
                "start_pos": 43298409,
                "end_pos": 43236012,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000097607.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000097607.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000095552.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000095552.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D4A9G3-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2P3/entry#D4A9G3-1",
            "sequence": {
                "sequence": "MSVAVVPAAVHPDSMLSEAEEPREVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI",
                "length": 212,
                "header": "tr|D4A9G3-1|A0A0G2K2P3_RAT Computationally mapped isoform of Tumor necrosis factor alpha-induced protein 8  OS=Rattus norvegicus OX=10116 GN=Tnfaip8 PE=3 SV=2 CANONICAL=A0A0G2K2P3-1"
            },
            "locus": {
                "chromosome": "18",
                "start_pos": 43298409,
                "end_pos": 43258524,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000021972.6",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000021972.6"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000021972.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000021972.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "R-RNO-1483255",
            "name": "PI Metabolism",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1483255",
            "resource": "Reactome",
            "description": "PI Metabolism"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A8D1D4H1-1",
            "protein_name": "Tumor necrosis factor alpha-induced protein 8",
            "gene_name": "TNFAIP8",
            "tax_id": 9823,
            "organism": "Sus scrofa",
            "sequence": {
                "sequence": "MSAVVAPAAAHPDTMNSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDFTFDRNVLSRLLNECRELLHQIIQRHLTAKSHGRINKVFDHFSDCDFLAALYNPFGNFKPHLQKLCDGINKMLDEDNI",
                "length": 212
            },
            "evidence": [
                {
                    "id": "A0A0G2K2P3",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2P3/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Pig",
            "common_name": "Pig"
        },
        {
            "uniprot_canonical_ac": "A4IF78-1",
            "protein_name": "Tumor necrosis factor alpha-induced protein 8",
            "gene_name": "TNFAIP8",
            "tax_id": 9913,
            "organism": "Bos taurus",
            "sequence": {
                "sequence": "MHFEAEESKEVATDVFNSKNLAVQAQKKILGKMASKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDFTFDRNVLSKLLNECREMLHQIIQRHLTTKSHGRVNNVFDHFSDCDFLAALYNPFGNYKPHLQKLCDGINKMLDEENI",
                "length": 198
            },
            "evidence": [
                {
                    "id": "A0A0G2K2P3",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2P3/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Bovine",
            "common_name": "Bovine"
        },
        {
            "uniprot_canonical_ac": "O95379-1",
            "protein_name": "Tumor necrosis factor alpha-induced protein 8",
            "gene_name": "TNFAIP8",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKMLDEENI",
                "length": 198
            },
            "evidence": [
                {
                    "id": "47561567",
                    "url": "http://www.informatics.jax.org/homology/47561567",
                    "database": "MGI"
                },
                {
                    "id": "A0A0G2K2P3",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2P3/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q7KVH9-1",
            "protein_name": "Protein salivary glands marred",
            "gene_name": "sigmar",
            "tax_id": 7227,
            "organism": "Drosophila melanogaster",
            "sequence": {
                "sequence": "MADNVFKSHDIGLRAQKKILSRMATKNIAKTFIDGTTASLLDNLYRLCKMHTGNKAKAEKLIKNIIKIVIKIGVLHRNNQFSDEELQKAELFKRKFQNTQLSIISFYEVDFTFDLPYLQKSIAESQVALKSIVQPHLTEKSLGRIDEVFDFFGEEALLETAFRPDSPYREVMGKIVADINAAMETGDI",
                "length": 188
            },
            "evidence": [
                {
                    "id": "A0A0G2K2P3",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2P3/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Fruit fly",
            "common_name": "Fruit fly"
        },
        {
            "uniprot_canonical_ac": "Q921Z5-1",
            "protein_name": "Tumor necrosis factor alpha-induced protein 8",
            "gene_name": "Tnfaip8",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MLSEAEEPREVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAERVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHEIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI",
                "length": 198
            },
            "evidence": [
                {
                    "id": "47561567",
                    "url": "http://www.informatics.jax.org/homology/47561567",
                    "database": "MGI"
                },
                {
                    "id": "A0A0G2K2P3",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2P3/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2P3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleoplasm",
                        "id": "GO:0005654",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2P3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "positive regulation of apoptotic process",
                        "id": "GO:0043065",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2P3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "defense response to Gram-positive bacterium",
                        "id": "GO:0050830",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2P3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "apoptotic process",
                        "id": "GO:0006915",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2P3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "small molecule binding",
                        "id": "GO:0036094",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2P3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cysteine-type endopeptidase inhibitor activity involved in apoptotic process",
                        "id": "GO:0043027",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043027",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2P3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "molecular sequestering activity",
                        "id": "GO:0140313",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140313",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2P3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "structures": [
        {
            "pdb_id": "AF-A0A0G2K2P3-F1",
            "pdb_chain": "global",
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