{
    "uniprot_canonical_ac": "A0A0G2K2K7-1",
    "uniprot_ac": "A0A0G2K2K7",
    "uniprot_id": "A0A0G2K2K7_RAT",
    "mass": {
        "chemical_mass": 71630.0,
        "monoisotopic_mass": 71630.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Il18rap",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7",
            "id": "A0A0G2K2K7"
        }
    ],
    "protein_names": [
        {
            "name": "Interleukin 18 receptor accessory protein",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2K7/entry#names_and_taxonomy",
            "id": "A0A0G2K2K7"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K2K7",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                }
            ],
            "common_name": "Rat",
            "glygen_name": "Rat",
            "reference_species": "Rattus norvegicus [10116]"
        }
    ],
    "gene": [
        {
            "name": "Il18rap",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7",
            "locus": {
                "chromosome": "9",
                "start_pos": 42800959,
                "end_pos": 42768220,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000054218",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000054218"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "A0A0G2K2K7",
            "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2K2K7",
            "database": "AlphaFoldDB",
            "categories": []
        },
        {
            "id": "ENSRNOG00000054218",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000054218",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "373540",
            "url": "https://www.ncbi.nlm.nih.gov/gene/373540",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000157",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003599",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR007110",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013151",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR015621",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015621",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR035897",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036179",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR041416",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041416",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "EPQKSHF",
            "url": "https://omabrowser.org/oma/group/EPQKSHF/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A0G2K2K7",
            "url": "https://www.orthodb.org/?gene=A0A0G2K2K7",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11890",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11890:SF23",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890:SF23",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00047",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01582",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF18452",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18452",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-9012546",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9012546",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_008756243",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008756243",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "727867",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=727867",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2K2K7",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K2K7-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MLCLGWVFLWFVAGEKTTGFNHSACTTKKLLWTYSARGAENFVLFCDLQELQKQDFSHRSQSSSTLGPAHQPCSGSEKDLSDVQWYMQPRSGGPLEEINRNSPHMQNKGTLRILAPQMNSIWSYICRPRSRRPQDTACCVKTVLEVKPQRNISCGSSAQDEQVLLLGSTGSIHCPSLSCQSDVRSPEMTWYKDGRLLPEYKKNPIEMEDIYDFHQGLYVCDYTQSDNVSSWTVRAVVQVRTIDEDTNVKPDILDPVTDTLDVELGKAFTLPCRVQFGFQRYSKPVIKWYVKESTQEWEISEFVEKRIQSTLKNEVIEHTVFLREVTQRDLSRKFVCFAQNSIGNTTRTIRLRKKEGVVFLYILLGMTVMLVGVLVAAALLYWHWIEVVLLCRTFKNKDETLRDKKEFDAFVSYANWSSPETEATGSLSEEHLALNLFPEVLENTYGYSLCLFERDVTPGGVYTDDIVSIIKRSRRGIFILSPRYINGPRVFELQAAVNLALVDQTLKLILIKFCSFQEPESLPYLVKKALRVLPTVTWKGLKSVHATSRFWTQIRYHMPVKNSNRFMFNWLRLIPKGFSPEKDLATQKPLGGMPNSGNSHGAQNRTPDAGNRHGAQNLLLSGHQKRC",
        "length": 627,
        "header": "tr|A0A0G2K2K7-1|A0A0G2K2K7_RAT Isoform 1 of Interleukin 18 receptor accessory protein  OS=Rattus norvegicus OX=10116 GN=Il18rap PE=3 SV=1 CANONICAL=A0A0G2K2K7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K2K7-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2K7/entry#A0A0G2K2K7-1",
            "sequence": {
                "sequence": "MLCLGWVFLWFVAGEKTTGFNHSACTTKKLLWTYSARGAENFVLFCDLQELQKQDFSHRSQSSSTLGPAHQPCSGSEKDLSDVQWYMQPRSGGPLEEINRNSPHMQNKGTLRILAPQMNSIWSYICRPRSRRPQDTACCVKTVLEVKPQRNISCGSSAQDEQVLLLGSTGSIHCPSLSCQSDVRSPEMTWYKDGRLLPEYKKNPIEMEDIYDFHQGLYVCDYTQSDNVSSWTVRAVVQVRTIDEDTNVKPDILDPVTDTLDVELGKAFTLPCRVQFGFQRYSKPVIKWYVKESTQEWEISEFVEKRIQSTLKNEVIEHTVFLREVTQRDLSRKFVCFAQNSIGNTTRTIRLRKKEGVVFLYILLGMTVMLVGVLVAAALLYWHWIEVVLLCRTFKNKDETLRDKKEFDAFVSYANWSSPETEATGSLSEEHLALNLFPEVLENTYGYSLCLFERDVTPGGVYTDDIVSIIKRSRRGIFILSPRYINGPRVFELQAAVNLALVDQTLKLILIKFCSFQEPESLPYLVKKALRVLPTVTWKGLKSVHATSRFWTQIRYHMPVKNSNRFMFNWLRLIPKGFSPEKDLATQKPLGGMPNSGNSHGAQNRTPDAGNRHGAQNLLLSGHQKRC",
                "length": 627,
                "header": "tr|A0A0G2K2K7-1|A0A0G2K2K7_RAT Isoform 1 of Interleukin 18 receptor accessory protein  OS=Rattus norvegicus OX=10116 GN=Il18rap PE=3 SV=1 CANONICAL=A0A0G2K2K7-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 42798258,
                "end_pos": 42776178,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000077303.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000077303.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000072281.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000072281.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "R-RNO-9012546",
            "name": "Interleukin-18 signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9012546",
            "resource": "Reactome",
            "description": "Interleukin-18 signaling"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A8V0YFL8-1",
            "protein_name": "Interleukin 18 receptor accessory protein",
            "gene_name": "IL18RAP",
            "tax_id": 9031,
            "organism": "Gallus gallus",
            "sequence": {
                "sequence": "MRPPPFGDRDPLHQLSCSREFSAESPTRLLGFARDCHQYAFATWTESKTILKESLNSSEYQSKLIKKMMLTFYWILALLITGTEVRGINLPGCSHVKPQVWYRAISDEEFVLQCALPDKDATNIYNNSVLKQHEVKWFWHQKDKGHLKAVEESFNVTLQGNALWFKPVRENASGIYICMIREKIPCLKIVLEVQTKAKAKCSGYGTNTLYLLAGNGNSIACPGRKCYSHINKTDVRWYKDGRQVEYRKTRNSLQLVDNEIYLKITYVQDAGIYVCDYDMSDNTTQWTMRTAVTVEVIAKTTIHPPNILYPSSVAILEAELGKPLELECRVQFGFERGTQRVIWKRDNKENLNEKLKQFETIETKETSVCPRYLKGHVLRHVAKLEEVTERDLKSDFICFAQNSVGNATAVIQLKKKQRVFFLYILCSAISILFAFLLCTAFIYQHWIEIVLMYRSYVAHNETTGDGKEFDAFVSYAKTDASESDSAFISEEKFALEILPDVLENKYGYKLCILERDILPGGAYTDEVVTAIRQSRRTIIILSPAYVSGPNIFELQAAVNCALEDKKIKLVLIKFQAFQEPETLPPVVKKALRILPVITWKPSISPAPNKKFWKYMHYHMPMNTTKVLGSCSLKCFFQRLFSLEHR",
                "length": 645
            },
            "evidence": [
                {
                    "id": "A0A0G2K2K7",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2K7/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Chicken",
            "common_name": "Chicken"
        },
        {
            "uniprot_canonical_ac": "F1MAT8-1",
            "protein_name": "Interleukin 18 receptor accessory protein",
            "gene_name": "IL18RAP",
            "tax_id": 9913,
            "organism": "Bos taurus",
            "sequence": {
                "sequence": "MRLSLGWILLWLVARGRIRGLNTPDCITEKPLRTYSARCGEEFVLFCDLPEPQKSHFYHGSQLSPTRASEYLPCSGSKNLSDVQWYLQPQNGDAAVEITQNAPQVIQEKSNLHFLSTGINHAGLYICRPRMRSPQENACCVRMILEVKPQTNMSCESSVSHKQHLLLGSVSSIYCPGLSHQSDAQSPEVTWYQNGKLLSEKRSNPIEVDEVYYYHQGTYVCDYTQTDNSSSWTVRAVVHVKTIVKNTNLKPDILDPIKDTLEVELGKPLMLNCTARFGFEINFNPVIKWYIRDSDQEWEIKTPKGRSVKSTLKDEVIERVVLLEKVTQSDLHRKFICFAQNSIGNTTQSIQLKKKTGVVFLYILLGAVMGLAGVLTAGALLYMYWIEIVLVYRTYWSKDKTLGDQKEFDAFVSYAKWSPFETEASSSLSEETLALNLLPDVLENKYGYTLCLLERDVAPGGVYTEDIVSIIKKSRRGIFILSPNYVSGPSIFELQAAVNLALEDQTLKLILIKFSSFQEPESLPHLVRRALRVLPSVTWKGLKSVPPNSRFWTQIRYHMPVKSSRGVTWNHLRTMPWIFSLEKTQ",
                "length": 585
            },
            "evidence": [
                {
                    "id": "A0A0G2K2K7",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2K7/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Bovine",
            "common_name": "Bovine"
        },
        {
            "uniprot_canonical_ac": "O95256-1",
            "protein_name": "Interleukin-18 receptor accessory protein",
            "gene_name": "IL18RAP",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MLCLGWIFLWLVAGERIKGFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWRGLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQLRITSRIFQWKGLSRTETTGRSSQPKEW",
                "length": 599
            },
            "evidence": [
                {
                    "id": "47573997",
                    "url": "http://www.informatics.jax.org/homology/47573997",
                    "database": "MGI"
                },
                {
                    "id": "A0A0G2K2K7",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2K7/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Z2B1-1",
            "protein_name": "Interleukin-18 receptor accessory protein",
            "gene_name": "Il18rap",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MLCLGWVFLWFVAGEKTTGFNHSACATKKLLWTYSARGAENFVLFCDLQELQEQKFSHASQLSPTQSPAHKPCSGSQKDLSDVQWYMQPRSGSPLEEISRNSPHMQSEGMLHILAPQTNSIWSYICRPRIRSPQDMACCIKTVLEVKPQRNVSCGNTAQDEQVLLLGSTGSIHCPSLSCQSDVQSPEMTWYKDGRLLPEHKKNPIEMADIYVFNQGLYVCDYTQSDNVSSWTVRAVVKVRTIGKDINVKPEILDPITDTLDVELGKPLTLPCRVQFGFQRLSKPVIKWYVKESTQEWEMSVFEEKRIQSTFKNEVIERTIFLREVTQRDLSRKFVCFAQNSIGNTTRTIRLRKKEEVVFVYILLGTALMLVGVLVAAAFLYWYWIEVVLLCRTYKNKDETLGDKKEFDAFVSYSNWSSPETDAVGSLSEEHLALNLFPEVLEDTYGYRLCLLDRDVTPGGVYADDIVSIIKKSRRGIFILSPSYLNGPRVFELQAAVNLALVDQTLKLILIKFCSFQEPESLPYLVKKALRVLPTVTWKGLKSVHASSRFWTQIRYHMPVKNSNRFMFNGLRIFLKGFSPEKDLVTQKPLEGMPKSGNDHGAQNLLLYSDQKRC",
                "length": 614
            },
            "evidence": [
                {
                    "id": "47573997",
                    "url": "http://www.informatics.jax.org/homology/47573997",
                    "database": "MGI"
                },
                {
                    "id": "A0A0G2K2K7",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2K7/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "cellular response to interleukin-18",
                        "id": "GO:0071351",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071351",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell population proliferation",
                        "id": "GO:0008283",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to hydrogen peroxide",
                        "id": "GO:0070301",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to cytokine stimulus",
                        "id": "GO:0071345",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071345",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "interleukin-18-mediated signaling pathway",
                        "id": "GO:0035655",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035655",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of natural killer cell mediated cytotoxicity",
                        "id": "GO:0045954",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045954",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neutrophil activation",
                        "id": "GO:0042119",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042119",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "interleukin-18 receptor complex",
                        "id": "GO:0045092",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045092",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 4,
                "go_terms": [
                    {
                        "name": "coreceptor activity",
                        "id": "GO:0015026",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "hydrolase activity",
                        "id": "GO:0016787",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2K7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2K7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "interleukin-18 binding",
                        "id": "GO:0042007",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042007",
                        "evidence": [
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