{
    "uniprot_canonical_ac": "A0A0G2K2B0-1",
    "uniprot_ac": "A0A0G2K2B0",
    "uniprot_id": "A0A0G2K2B0_RAT",
    "mass": {
        "chemical_mass": 108927.0,
        "monoisotopic_mass": 108927.0
    },
    "refseq": {
        "ac": "XP_006232288",
        "name": "polyhomeotic-like protein 3 isoform X1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006232288"
    },
    "gene_names": [
        {
            "name": "Phc3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0",
            "id": "A0A0G2K2B0"
        },
        {
            "name": "Phc3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006232288",
            "id": "XP_006232288"
        }
    ],
    "protein_names": [
        {
            "name": "Polyhomeotic homolog 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2B0/entry#names_and_taxonomy",
            "id": "A0A0G2K2B0"
        },
        {
            "name": "polyhomeotic-like protein 3 isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006232288",
            "id": "XP_006232288"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:162",
            "recommended_name": {
                "id": "DOID:162",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:162",
                "name": "cancer",
                "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis."
            },
            "synonyms": [
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "malignant neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "malignant tumor",
                    "description": ""
                },
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "primary cancer",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "162",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:162"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K2B0",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                }
            ],
            "common_name": "Rat",
            "glygen_name": "Rat",
            "reference_species": "Rattus norvegicus [10116]"
        }
    ],
    "gene": [
        {
            "name": "Phc3",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0",
            "locus": {
                "chromosome": "2",
                "start_pos": 112476540,
                "end_pos": 112408531,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000009491",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000009491"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "A0A0G2K2B0",
            "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2K2B0",
            "database": "AlphaFoldDB",
            "categories": []
        },
        {
            "id": "ENSRNOG00000009491",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000009491",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd09577",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09577",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "310258",
            "url": "https://www.ncbi.nlm.nih.gov/gene/310258",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001660",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR012313",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012313",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013761",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR038603",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038603",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR050548",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "DRHAVQX",
            "url": "https://omabrowser.org/oma/group/DRHAVQX/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "D3ZS50",
            "url": "https://www.orthodb.org/?gene=D3ZS50",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12247",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12247:SF88",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF88",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00536",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF21319",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21319",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-2559580",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2559580",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-3108214",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3108214",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-3899300",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3899300",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-4551638",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-4551638",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-4570464",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-4570464",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-8939243",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8939243",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-8953750",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8953750",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_006232288",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006232288",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1307998",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307998",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2K2B0",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K2B0-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AP38",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AP38",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AP38-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AP38-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6G4B4",
            "url": "https://www.uniprot.org/uniprot/A0A8I6G4B4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6G4B4-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6G4B4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZS50",
            "url": "https://www.uniprot.org/uniprot/D3ZS50",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZS50-1",
            "url": "https://www.uniprot.org/uniprot/D3ZS50-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAEAEFKDHSTAMESEPSSGTSVSTTASSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLMSRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLGVLSSSQNGPPKSAGQTQSLTICHNKTTVTSSKISQRDPSPESKKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLILQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPASSNAQSQQHCSPIQSHPPPLTVSPSQAQSAQQSVVVSPPPAHSPSQSPTIIIHPQALVQPHPLVSSALHTGPNLQQATADQVQSTAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPTSHQQYSTLQSSPIPIATPPQMSASPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVGMHLNQCHLHKVFSLKVYQVEDVCEEERPEESDECARMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHVSAPAPPLLMPAASTRSSSTSLASSTPSLENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPEGAAREHILRQLPITYPSAEEDLASRDDPVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSTMNMKLGPALKICARINSLKDS",
        "length": 1011,
        "header": "tr|A0A0G2K2B0-1|A0A0G2K2B0_RAT Isoform 1 of Polyhomeotic homolog 3  OS=Rattus norvegicus OX=10116 GN=Phc3 PE=1 SV=2 CANONICAL=A0A0G2K2B0-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K2B0-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2B0/entry#A0A0G2K2B0-1",
            "sequence": {
                "sequence": "MAEAEFKDHSTAMESEPSSGTSVSTTASSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLMSRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLGVLSSSQNGPPKSAGQTQSLTICHNKTTVTSSKISQRDPSPESKKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLILQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPASSNAQSQQHCSPIQSHPPPLTVSPSQAQSAQQSVVVSPPPAHSPSQSPTIIIHPQALVQPHPLVSSALHTGPNLQQATADQVQSTAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPTSHQQYSTLQSSPIPIATPPQMSASPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVGMHLNQCHLHKVFSLKVYQVEDVCEEERPEESDECARMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHVSAPAPPLLMPAASTRSSSTSLASSTPSLENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPEGAAREHILRQLPITYPSAEEDLASRDDPVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSTMNMKLGPALKICARINSLKDS",
                "length": 1011,
                "header": "tr|A0A0G2K2B0-1|A0A0G2K2B0_RAT Isoform 1 of Polyhomeotic homolog 3  OS=Rattus norvegicus OX=10116 GN=Phc3 PE=1 SV=2 CANONICAL=A0A0G2K2B0-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 112475999,
                "end_pos": 112408778,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000089477.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000089477.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000072169.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000072169.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AP38-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2B0/entry#A0A8I6AP38-1",
            "sequence": {
                "sequence": "VSSTRFKDHSTAMESEPSSGTSVSTTASSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLMSRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLGVLSSSQNGPPKSAGQTQSLTICHNKTTVTSSKISQRDPSPESKKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLILQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPASSNAQSQQHCSPIQSHPPPLTVSPSQAQSAQQSVVVSPPPAHSPSQSPTIIIHPQALVQPHPLVSSALHTGPNLQQATADQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVCGLSLQVYQVEDVCEEERPEESDECARMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHVSAPAPPLLMPAASTRSSSTSLASSTPSLENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPEGAAREHILRQLPITYPSAEEDLASRDDPVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSTMNMKLGPALKICARINSLKDS",
                "length": 910,
                "header": "tr|A0A8I6AP38-1|A0A8I6AP38_RAT Computationally mapped isoform of Polyhomeotic homolog 3  OS=Rattus norvegicus OX=10116 GN=Phc3 PE=1 SV=1 CANONICAL=A0A0G2K2B0-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 112475999,
                "end_pos": 112412401,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000109697.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000109697.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000096050.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000096050.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6G4B4-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2B0/entry#A0A8I6G4B4-1",
            "sequence": {
                "sequence": "VSSTRFKDHSTAMESEPSSGTSVSTTASSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLMSRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLGVLSSSQNGPPKSAGQTQSLTICHNKTTVTSSKISQRDPSPESKKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLILQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPASSNAQSQQHCSPIQSHPPPLTVSPSQAQSAQQSVVVSPPPAHSPSQSPTIIIHPQALVQPHPLVSSALHTGPNLQQATADQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVGMHLNQCHLHKVFSLKVYQVEDVCEEERPEESDECARMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHVSAPAPPLLMPAASTRSSSTSLASSTPSLENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPEGAAREHILRQLPITYPSAEEDLASRDDPVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSTMNMKLGPALKICARINSLKDS",
                "length": 920,
                "header": "tr|A0A8I6G4B4-1|A0A8I6G4B4_RAT Computationally mapped isoform of Polyhomeotic homolog 3  OS=Rattus norvegicus OX=10116 GN=Phc3 PE=1 SV=1 CANONICAL=A0A0G2K2B0-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 112475999,
                "end_pos": 112412401,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000110653.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000110653.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000078977.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000078977.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3ZS50-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2K2B0/entry#D3ZS50-1",
            "sequence": {
                "sequence": "MESEPSSGTSVSTTASSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLMSRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMVQNLTLRSQKLGVLSSSQNGPPKSAGQTQSLTICHNKTTVTSSKISQRDPSPESKKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLILQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPASSNAQSQQHCSPIQSHPPPLTVSPSQAQSAQQSVVVSPPPAHSPSQSPTIIIHPQALVQPHPLVSSALHTGPNLQQATADQVQSTAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPTSHQQYSTLQSSPIPIATPPQMSASPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEERPEESDECARMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHVSAPAPPLLMPAASTRSSSTSLASSTPSLENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPEGAAREHILRQLPITYPSAEEDLASRDDPVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSTMNMKLGPALKICARINSLKDS",
                "length": 950,
                "header": "tr|D3ZS50-1|D3ZS50_RAT Computationally mapped isoform of Polyhomeotic homolog 3  OS=Rattus norvegicus OX=10116 GN=Phc3 PE=1 SV=2 CANONICAL=A0A0G2K2B0-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 112475999,
                "end_pos": 112412437,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000066495.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000066495.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000063002.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000063002.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "O-linked",
            "subtype": "other",
            "prediction_tool": "isoglyp",
            "mining_tool": "",
            "site_category": "predicted",
            "site_category_dict": {
                "predicted": true
            },
            "site_seq": "",
            "relation": "attached",
            "comment": "",
            "start_pos": 145,
            "start_aa": "T",
            "end_pos": 145,
            "end_aa": "T",
            "residue": "Thr",
            "site_lbl": "Thr145",
            "evidence": [
                {
                    "id": "GLY_001157",
                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_001157"
                }
            ],
            "filter_code": "00000000000000001000.00000000001000.1.01000"
        },
        {
            "glytoucan_ac": "",
            "type": "O-linked",
            "subtype": "other",
            "prediction_tool": "isoglyp",
            "mining_tool": "",
            "site_category": "predicted",
            "site_category_dict": {
                "predicted": true
            },
            "site_seq": "",
            "relation": "attached",
            "comment": "",
            "start_pos": 649,
            "start_aa": "T",
            "end_pos": 649,
            "end_aa": "T",
            "residue": "Thr",
            "site_lbl": "Thr649",
            "evidence": [
                {
                    "id": "GLY_001157",
                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_001157"
                }
            ],
            "filter_code": "00000000000000001000.00000000001000.1.01000"
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.",
            "journal": "Nat. Commun.",
            "date": "2012",
            "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K2B0",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22673903",
                    "url": "https://glygen.org/publication/PubMed/22673903"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "R-RNO-2559580",
            "name": "Oxidative Stress Induced Senescence",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2559580",
            "resource": "Reactome",
            "description": "Oxidative Stress Induced Senescence"
        },
        {
            "id": "R-RNO-3108214",
            "name": "SUMOylation of DNA damage response and repair proteins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3108214",
            "resource": "Reactome",
            "description": "SUMOylation of DNA damage response and repair proteins"
        },
        {
            "id": "R-RNO-3899300",
            "name": "SUMOylation of transcription cofactors",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3899300",
            "resource": "Reactome",
            "description": "SUMOylation of transcription cofactors"
        },
        {
            "id": "R-RNO-4551638",
            "name": "SUMOylation of chromatin organization proteins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-4551638",
            "resource": "Reactome",
            "description": "SUMOylation of chromatin organization proteins"
        },
        {
            "id": "R-RNO-4570464",
            "name": "SUMOylation of RNA binding proteins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-4570464",
            "resource": "Reactome",
            "description": "SUMOylation of RNA binding proteins"
        },
        {
            "id": "R-RNO-8939243",
            "name": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8939243",
            "resource": "Reactome",
            "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
        },
        {
            "id": "R-RNO-8953750",
            "name": "Transcriptional Regulation by E2F6",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8953750",
            "resource": "Reactome",
            "description": "Transcriptional Regulation by E2F6"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A3Q1LUV4-1",
            "protein_name": "Polyhomeotic homolog 3",
            "gene_name": "PHC3",
            "tax_id": 9913,
            "organism": "Bos taurus",
            "sequence": {
                "sequence": "VLSARFKDHSTAMDSEPNPGTSSVSTTNSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPSSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPPTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYPPIQPHPLIKHQQIPLHSPPPKVSHHQLILQQQQQQIQPITLQSPTQDPPPSQHCIPLQNHGLPPAPSSAQSQHCSPIQSHPPPLAMSPSQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGSNLQQSTANQVQPTTQLNLSSHLPLPASPVVHIGPVQQSTLVSPGQQIVSPTSHQQYSTLQSSPIPIATPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESEDCVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMPSSVPSVENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKRRPVLDNQVINSVCVQPELQNNAKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEEDLASHEDAVPSAMTTRLRRQSERERERELRDVRMRKMPENSGLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARINSLKES",
                "length": 996
            },
            "evidence": [
                {
                    "id": "A0A0G2K2B0",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2B0/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Bovine",
            "common_name": "Bovine"
        },
        {
            "uniprot_canonical_ac": "I3LJU0-1",
            "protein_name": "Polyhomeotic homolog 3",
            "gene_name": "PHC3",
            "tax_id": 9823,
            "organism": "Sus scrofa",
            "sequence": {
                "sequence": "MAEAEFKDHSTAMDSEPNSGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPPTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTNQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYPPIQPHPLIKHQQIPLHSPPPKVSHHQLILQQQQQQIQPITLQNPTQDPPPSQHCIPLQNHGLPPAPSSAQSQHCSPIQSHPPPLTMSPSQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGSNLQQSTANQVQPTAQLNLPSHLPLPASPVVHIGPVQQSTLVSPGQQIVSPTSHQQYSALQSSPIPIATPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPSASVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGREDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMPSSIPNVENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEHPVKKRPILDNQMINSVCVQPELQNNAKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFTLSRWNRKPDNQSLGHRGRRPSGPDGAAREHILRQLPLTYPSAEEDLASHEDSVPSAMTTRLRRQSERERERELRDVRMRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARINSLKES",
                "length": 995
            },
            "evidence": [
                {
                    "id": "A0A0G2K2B0",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2B0/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Pig",
            "common_name": "Pig"
        },
        {
            "uniprot_canonical_ac": "Q8CHP6-1",
            "protein_name": "Polyhomeotic-like protein 3",
            "gene_name": "Phc3",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MDSEPSSGTSVSTTASSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSILSASPAPAQLMNRSQTSSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLGVLSSSQNGSPKSAGQTQSLTICHNKTTVTSSKISQRDPSPESKKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLLLQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPAPSNAQPQHCSPVQSHPPPLTVSPNQAQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQTGPNLQQAAADQVQSTAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQMVSPTSHQQYSALQSSPIPIATPPQMSASPPAQLPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECARMDRTPPPPTLSPAAVTVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHASAPAPPLLIPAASTRSSSTSLASSTPSLENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEIEDMMAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPEGAAREHILRQLPITYPSAEEDVASHEDPVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSAMNMKLGPALKICARINSLKDS",
                "length": 981
            },
            "evidence": [
                {
                    "id": "47567732",
                    "url": "http://www.informatics.jax.org/homology/47567732",
                    "database": "MGI"
                },
                {
                    "id": "A0A0G2K2B0",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2B0/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q8NDX5-1",
            "protein_name": "Polyhomeotic-like protein 3",
            "gene_name": "PHC3",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARINSLKES",
                "length": 983
            },
            "evidence": [
                {
                    "id": "47567732",
                    "url": "http://www.informatics.jax.org/homology/47567732",
                    "database": "MGI"
                },
                {
                    "id": "A0A0G2K2B0",
                    "url": "https://omabrowser.org/oma/group/A0A0G2K2B0/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 4,
                "go_terms": [
                    {
                        "name": "DNA binding",
                        "id": "GO:0003677",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2B0",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chromatin binding",
                        "id": "GO:0003682",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2B0",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "zinc ion binding",
                        "id": "GO:0008270",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2B0",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone binding",
                        "id": "GO:0042393",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2B0",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2B0",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleoplasm",
                        "id": "GO:0005654",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2B0",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "PcG protein complex",
                        "id": "GO:0031519",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2B0",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "PRC1 complex",
                        "id": "GO:0035102",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2B0",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "negative regulation of DNA-templated transcription",
                        "id": "GO:0045892",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K2B0",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2B0"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 139,
            "end_pos": 141,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 226,
            "end_pos": 228,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 259,
            "end_pos": 261,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 781,
            "end_pos": 783,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 788,
            "end_pos": 790,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 841,
            "end_pos": 843,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 859,
            "end_pos": 861,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "structures": [
        {
            "pdb_id": "AF-A0A0G2K2B0-F1",
            "pdb_chain": "global",
            "start_pos": 1,
            "end_pos": 1011,
            "overlap": "1.0",
            "method": "AlphaFold",
            "type": "alphafold",
            "resolution": -1.0,
            "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0G2K2B0-F1.pdb"
        }
    ],
    "synthesized_glycans": [],
    "enzyme_annotation": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [
            145,
            649
        ],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 139,
                "end_pos": 141
            },
            {
                "start_pos": 226,
                "end_pos": 228
            },
            {
                "start_pos": 259,
                "end_pos": 261
            },
            {
                "start_pos": 781,
                "end_pos": 783
            },
            {
                "start_pos": 788,
                "end_pos": 790
            },
            {
                "start_pos": 841,
                "end_pos": 843
            },
            {
                "start_pos": 859,
                "end_pos": 861
            }
        ]
    },
    "section_stats": [
        {
            "table_id": "glycosylation",
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