{
    "uniprot_canonical_ac": "A0A0G2JYP9-1",
    "uniprot_ac": "A0A0G2JYP9",
    "uniprot_id": "A0A0G2JYP9_RAT",
    "mass": {
        "chemical_mass": 33945.0,
        "monoisotopic_mass": 33945.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Rnf212",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9",
            "id": "A0A0G2JYP9"
        }
    ],
    "protein_names": [
        {
            "name": "Ring finger protein 212",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYP9/entry#names_and_taxonomy",
            "id": "A0A0G2JYP9"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0112351",
            "recommended_name": {
                "id": "DOID:0112351",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0112351",
                "name": "spermatogenic failure 62",
                "description": "A spermatogenic failure that is characterized by male infertility due to nonobstructive azoospermia with complete metaphase arrest at the spermatocyte stage that has_material_basis_in homozygous or compound heterozygous mutation in the RNF212 gene on chromosome 4p16.3."
            },
            "synonyms": [
                {
                    "id": "DOID:0112351",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0112351",
                    "name": "SPGF62",
                    "description": ""
                },
                {
                    "id": "MONDO:0030508",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0030508",
                    "name": "spermatogenic failure 62",
                    "description": ""
                },
                {
                    "id": "MONDO:0030508",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0030508",
                    "name": "SPGF62",
                    "description": ""
                },
                {
                    "id": "MIM:619673",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/619673",
                    "name": "Spermatogenic failure 62",
                    "description": "Spermatogenic failure 62"
                }
            ],
            "evidence": [
                {
                    "id": "0112351",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0112351"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2JYP9",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9"
                }
            ],
            "common_name": "Rat",
            "glygen_name": "Rat",
            "reference_species": "Rattus norvegicus [10116]"
        }
    ],
    "gene": [
        {
            "name": "Rnf212",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9",
            "locus": {
                "chromosome": "14",
                "start_pos": 987831,
                "end_pos": 949448,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000059010",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000059010"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "A0A0G2JYP9",
            "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2JYP9",
            "database": "AlphaFoldDB",
            "categories": []
        },
        {
            "id": "ENSRNOG00000059010",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000059010",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd16746",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16746",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001841",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013083",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017907",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR042123",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR042123",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "VCCNSCF",
            "url": "https://omabrowser.org/oma/group/VCCNSCF/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A0G2JYP9",
            "url": "https://www.orthodb.org/?gene=A0A0G2JYP9",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR22663",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22663",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR22663:SF21",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22663:SF21",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF14634",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14634",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1588767",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1588767",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2JYP9",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2JYP9-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5XWM3",
            "url": "https://www.uniprot.org/uniprot/A0A8I5XWM3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5XWM3-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5XWM3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MASWVFCNRCFQPPHRKSSFSLTSCGHVFCDSCILKGKKNECMICEVPCQTVLLSKHTNSNVQTFFLDIDGLCKKYSQEISQISEFQEKHRRRLVTFYREKISQLEESLRKSVLQIKQLQSMRSSQQPAFNTIKNSVSTKPNGYIFLPPNSSLPDRIESMDIDLTSPARKPETAAGPSRISLISPPQDGRMGSASCRGPQHLSLTPSHASTAKAFRVPPLQVPYKELSPLPASQLSSRATQAPSPSISSSWTGPPRQPISISGLLQRQSAGSASPRGMNTEKMSPFLPSTPANLRSVASPWQVCVHR",
        "length": 307,
        "header": "tr|A0A0G2JYP9-1|A0A0G2JYP9_RAT Isoform 1 of Ring finger protein 212  OS=Rattus norvegicus OX=10116 GN=Rnf212 PE=4 SV=2 CANONICAL=A0A0G2JYP9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2JYP9-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYP9/entry#A0A0G2JYP9-1",
            "sequence": {
                "sequence": "MASWVFCNRCFQPPHRKSSFSLTSCGHVFCDSCILKGKKNECMICEVPCQTVLLSKHTNSNVQTFFLDIDGLCKKYSQEISQISEFQEKHRRRLVTFYREKISQLEESLRKSVLQIKQLQSMRSSQQPAFNTIKNSVSTKPNGYIFLPPNSSLPDRIESMDIDLTSPARKPETAAGPSRISLISPPQDGRMGSASCRGPQHLSLTPSHASTAKAFRVPPLQVPYKELSPLPASQLSSRATQAPSPSISSSWTGPPRQPISISGLLQRQSAGSASPRGMNTEKMSPFLPSTPANLRSVASPWQVCVHR",
                "length": 307,
                "header": "tr|A0A0G2JYP9-1|A0A0G2JYP9_RAT Isoform 1 of Ring finger protein 212  OS=Rattus norvegicus OX=10116 GN=Rnf212 PE=4 SV=2 CANONICAL=A0A0G2JYP9-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 987763,
                "end_pos": 949549,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000085898.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000085898.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000070745.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000070745.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5XWM3-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2JYP9/entry#A0A8I5XWM3-1",
            "sequence": {
                "sequence": "MRSSQQPAFNTIKNSVSTKPNGYIFLPPNSSLPDRIESMDIDLTSPARKPETAAGPSRISLISPPQDGRMGSASCRGPQHLSLTPSHASTAKAFRVSVP",
                "length": 99,
                "header": "tr|A0A8I5XWM3-1|A0A0G2JYP9_RAT Computationally mapped isoform of Ring finger protein 212  OS=Rattus norvegicus OX=10116 GN=Rnf212 PE=4 SV=1 CANONICAL=A0A0G2JYP9-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 987666,
                "end_pos": 976151,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000096364.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000096364.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000077915.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000077915.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A1D5P1V9-1",
            "protein_name": "Ring finger protein 212",
            "gene_name": "RNF212",
            "tax_id": 9031,
            "organism": "Gallus gallus",
            "sequence": {
                "sequence": "MAIRVFCNSCFCEPRKATPRFIFTSCGHVICELCLQKGKKDECLICRTPCRTVFLSKETSPEIQSLFMGIDTLCKKYSKEITQISEFQEKNRKHLLAYHREKKVKLEESLRKARQQLHQIQSMKPPQQVTQLPFASTSRNPLSMPSRRLNGCSSYSLQPSHPSTSETMESMEVDHVPSPMRKPETMTGPVRLSVITPPQDGRMGSVSYRSSQSSGITSSQSTAVSTRSTPVGLPHNGCSLISPSGSQSSRRGSWSASDFRTPPLYQFTLPSPQSSVTRPPITISGILQRQYLGSASFGGQTAER",
                "length": 304
            },
            "evidence": [
                {
                    "id": "A0A0G2JYP9",
                    "url": "https://omabrowser.org/oma/group/A0A0G2JYP9/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Chicken",
            "common_name": "Chicken"
        },
        {
            "uniprot_canonical_ac": "F6TQD1-1",
            "protein_name": "Probable E3 SUMO-protein ligase RNF212",
            "gene_name": "Rnf212",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MASWVFCNRCFQSPHRKSSFSLTSCGHVYCHSCLLKGTKNECVICQAPCQTVLLSKHTNSNIQTFFLGIDGLCKKYSQETSQISEFQEKHRRRLVAFYQEKISQLEESLRKSVLQIKQLQSMRSSQQPAFNKIKNSVSTKPNGYLFLPPNSSLPDRIESMDIDLTPPARKPEMSAGPSRISVISPPQDGRMGSVTCRGPQHLSLTPSHASMTKASRVPPLQMPYKELSPPPASQLSSRATQGPSPSVSSSWTGPPRQPISISGLLQRQCAGSASPRGMDTEKMSPFLPSTPTNLRSVASPWHACVHR",
                "length": 307
            },
            "evidence": [
                {
                    "id": "A0A0G2JYP9",
                    "url": "https://omabrowser.org/oma/group/A0A0G2JYP9/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q495C1-1",
            "protein_name": "Probable E3 SUMO-protein ligase RNF212",
            "gene_name": "RNF212",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MANWVFCNRCFQPPHRTSCFSLTNCGHVYCDACLGKGKKNECLICKAPCRTVLLSKHTDADIQAFFMSIDSLCKKYSRETSQILEFQEKHRKRLLAFYREKISRLEESLRKSVLQIEQLQSMRSSQQTAFSTIKSSVSTKPHGCLLPPHSSAPDRLESMEVDLSPSPIRKSEIAAGPARISMISPPQDGRMGPHLTASFCFIPWLTLSKPPVPGECVISRGSPCFCIDVCPHWLLLLAFSSGRHGELTNSKTLPIYAEVQRAVLFPFQQAEGTLDTFRTPAVSVVFPLCQFERKKSF",
                "length": 297
            },
            "evidence": [
                {
                    "id": "A0A0G2JYP9",
                    "url": "https://omabrowser.org/oma/group/A0A0G2JYP9/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "SUMO transferase activity",
                        "id": "GO:0019789",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019789",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JYP9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "metal ion binding",
                        "id": "GO:0046872",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JYP9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 5,
                "go_terms": [
                    {
                        "name": "reciprocal meiotic recombination",
                        "id": "GO:0007131",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JYP9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "meiotic gene conversion",
                        "id": "GO:0006311",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006311",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JYP9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chiasma assembly",
                        "id": "GO:0051026",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051026",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JYP9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein sumoylation",
                        "id": "GO:0016925",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JYP9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "homologous chromosome pairing at meiosis",
                        "id": "GO:0007129",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JYP9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "synaptonemal complex",
                        "id": "GO:0000795",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000795",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JYP9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JYP9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 150,
            "end_pos": 152,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "structures": [
        {
            "pdb_id": "AF-A0A0G2JYP9-F1",
            "pdb_chain": "global",
            "start_pos": 1,
            "end_pos": 307,
            "overlap": "1.0",
            "method": "AlphaFold",
            "type": "alphafold",
            "resolution": -1.0,
            "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0G2JYP9-F1.pdb"
        }
    ],
    "synthesized_glycans": [],
    "enzyme_annotation": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 150,
                "end_pos": 152
            }
        ]
    },
    "section_stats": [
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                {
                    "field": "n_linked_glycan_sites",
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        {
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            "sort_fields": []
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        {
            "table_id": "glycosylation_automatic_literature_mining",
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