{ "uniprot_canonical_ac": "A0A0G2JDS2-1", "uniprot_ac": "A0A0G2JDS2", "uniprot_id": "A0A0G2JDS2_MOUSE", "mass": { "chemical_mass": 47746.0, "monoisotopic_mass": 47746.0 }, "refseq": { "ac": "NP_001074285", "name": "chitinase like precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074285" }, "gene_names": [ { "name": "Chil5", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2JDS2", "id": "A0A0G2JDS2" }, { "name": "Bclp; Bclp1; Bclp2; Chi3l7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074285", "id": "NP_001074285" }, { "name": "Chil5", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074285", "id": "NP_001074285" } ], "protein_names": [ { "name": "Chitinase-like 5", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JDS2/entry#names_and_taxonomy", "id": "A0A0G2JDS2" }, { "name": "chitinase like precursor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074285", "id": "NP_001074285" }, { "name": "chitinase like protein 2; chitinase 3-like 7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074285", "id": "NP_001074285" } ], "function": [], "disease": [ { "disease_id": "DOID:0050127", "recommended_name": { "id": "DOID:0050127", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050127", "name": "sinusitis", "description": "A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. 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The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, bronchial", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, diminished response to Antileukotriene treatment 1N", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, protection against", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, susceptibility to", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma-related traits, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "evidence": [ { "id": "2841", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JDS2", "url": "https://www.uniprot.org/uniprot/A0A0G2JDS2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "gene": [ { "name": "Chil5", "url": "https://www.uniprot.org/uniprot/A0A0G2JDS2", "locus": { "chromosome": "3", "start_pos": 105924235, "end_pos": 105940130, "strand": "+", "evidence": [ { "database": 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GN=Chil5 PE=4 SV=1 CANONICAL=A0A0G2JDS2-1" }, "isoforms": [ { "isoform_ac": "A0A0G2JDS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JDS2/entry#A0A0G2JDS2-1", "sequence": { "sequence": "MTKLILVTGLALLLNPQLGSAYQLMCYYNNVAQNRPKLGSFNPADIDPCLCTHLIYAFAGMQNNKVTMRSMNDLTDYQALNTLKSRNVQLKTLLAIGGRDFGPAPFSAMVSTPHNQQTFINSAIKFLRQYGFDGLNLDWQFPGSRGSPSRDKHLFTVLVQKIREAFELEAIENKSPRLMVTATVAGVISTIQSGYEIPQLSHFLDYIQVMTYNLHGSQDGYTGENSPLYKSLNDTGINTLLNVDYIMTYWNENGAAPEKLIVGFPAYGQTFTLSDPSNNGISAPTASAGTLGPYTEESGTWAYYEICSFLNDGATEAWDSAQEVPYAYQGNKWVGYDNVKSFRIKAEWLKQNNLGGAMLWTLDMDDFTGSFCNQGQFPLTSTLKNALLVYSTSCMASVSDLQQVNAPLYSGNRNWKRGSKAMDSVSPVPRE", "length": 431, "header": "tr|A0A0G2JDS2-1|A0A0G2JDS2_MOUSE Isoform 1 of Chitinase-like 5 OS=Mus musculus OX=10090 GN=Chil5 PE=4 SV=1 CANONICAL=A0A0G2JDS2-1" }, "locus": { "chromosome": "3", "start_pos": 105940130, "end_pos": 105924451, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000200146.2", "url": 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Peptide", "id": "ENSMUSP00000065043.5", "url": "https://www.ensembl.org/id/ENSMUSP00000065043.5" } ] } }, { "isoform_ac": "F7D8T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2JDS2/entry#F7D8T8-1", "sequence": { "sequence": "XGGRDFGPAPFSAMVSTPHNQQTFINSAIKFLRQYGFDGLNLDWQFPGSRGSPSRDKHLFTVLVQLPRLHPGHDLQSPWLPRWLYWGKQPTLQIPK", "length": 96, "header": "tr|F7D8T8-1|A0A0G2JDS2_MOUSE Computationally mapped isoform of Chitinase-like 5 OS=Mus musculus OX=10090 GN=Chil5 PE=4 SV=1 CANONICAL=A0A0G2JDS2-1" }, "locus": { "chromosome": "3", "start_pos": 105932232, "end_pos": 105926935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000054973.8", "url": "https://www.ensembl.org/id/ENSMUST00000054973.8" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000052345.4", "url": "https://www.ensembl.org/id/ENSMUSP00000052345.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "mmu:229687", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:229687", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9BZP6-1", "protein_name": "Acidic mammalian chitinase", "gene_name": "CHIA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKLILLTGLVLILNLQLGSAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAGRQNNEITTIEWNDVTLYQAFNGLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAPQEVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGNGSGSSSSGGSSGGSGFCAVRANGLYPVANNRNAFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA", "length": 476 }, "evidence": [ { "id": "47557374", "url": "http://www.informatics.jax.org/homology/47557374", "database": "MGI" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { 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