{ "uniprot_canonical_ac": "A0A0B7P9G0-1", "uniprot_ac": "A0A0B7P9G0", "uniprot_id": "UEX_DROME", "mass": { "chemical_mass": 93283.0, "monoisotopic_mass": 93283.0 }, "refseq": { "ac": "NP_001104390", "name": "unextended, isoform F", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390" }, "gene_names": [ { "name": "uex", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0", "id": "A0A0B7P9G0" }, { "name": "41Ad; CG40084; CG42595; CR41594; Dmel\\CG42595; EMS45-73; GroupIII; IR3; l(2)41Ad; l(2)EMS34-7; l(2)IR3; l(2R)A'; l(2R)EMS45-73; l(2Rh)IR3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390", "id": "NP_001104390" }, { "name": "41Ad", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0", "id": "A0A0B7P9G0" }, { "name": "CG42595", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0", "id": "A0A0B7P9G0" }, { "name": "GroupIII", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0", "id": "A0A0B7P9G0" }, { "name": "l(2)41Ad", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0", "id": "A0A0B7P9G0" }, { "name": "uex", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390", "id": "NP_001104390" } ], "protein_names": [ { "name": "Unextended protein", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P9G0/entry#names_and_taxonomy", "id": "A0A0B7P9G0" }, { "name": "CG42595-PF; uex-PF; lethal (2) IR3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390", "id": "NP_001104390" }, { "name": "Putative metal transporter uex", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P9G0/entry#names_and_taxonomy", "id": "A0A0B7P9G0" }, { "name": "unextended, isoform F", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390", "id": "NP_001104390" } ], "function": [ { "annotation": "Probable metal transporter (By similarity). Acts downstream of PRL-1 and protects the nervous system against olfactory carbon dioxide stimulation (PubMed:31404830).", "evidence": [ { "database": "UniProtKB", "id": "A0A0B7P9G0", "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0#function" }, { "database": "PubMed", "id": "31404830", "url": "https://glygen.org/publication/PubMed/31404830" }, { "database": "UniProtKB", "id": "Q3TWN3", "url": "https://www.uniprot.org/uniprot/Q3TWN3#function" } ] } ], "disease": [ { "disease_id": "DOID:0060884", "recommended_name": { "id": "DOID:0060884", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060884", "name": "renal hypomagnesemia 6", "description": "A hypomagnesemia characterized by autosomal dominant inheritance of severely lowered serum magnesium levels without other electrolyte disturbances or abnormalities in urinary magnesium excretion that has_material_basis_in heterozygous mutation in the CNNM2 gene on chromosome 10q24." }, "synonyms": [ { "id": "DOID:0060884", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060884", "name": "HOMG6", "description": "" }, { "id": "MONDO:0013480", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013480", "name": "renal hypomagnesemia 6", "description": "" }, { "id": "MONDO:0013480", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013480", "name": "HOMG6", "description": "" }, { "id": "MONDO:0013480", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013480", "name": "renal hypomagnesemia type 6", "description": "" }, { "id": "MONDO:0013480", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013480", "name": "hypomagnesemia 6, renal", "description": "" }, { "id": "MONDO:0013480", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013480", "name": "renal hypomagnesemia-6", "description": "" }, { "id": "MIM:613882", "resource": "MIM", "url": "https://www.omim.org/entry/613882", "name": "Hypomagnesemia 6", "description": "Hypomagnesemia 6" } ], "evidence": [ { "id": "0060884", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0060884" } ] }, { "disease_id": "DOID:0111404", "recommended_name": { "id": "DOID:0111404", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111404", "name": "Jalili syndrome", "description": "A syndrome characterized by amelogenesis imperfecta and cone-rod retinal dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in CNNM4 on chromosome 2q11.2." }, "synonyms": [ { "id": "DOID:0111404", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111404", "name": "Cone rod dystrophy-amelogenesis imperfecta syndrome", "description": "" }, { "id": "DOID:0111404", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111404", "name": "cone-rod dystrophy and 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