{ "uniprot_canonical_ac": "A0A0B4LIC4-1", "uniprot_ac": "A0A0B4LIC4", "uniprot_id": "A0A0B4LIC4_DROME", "mass": { "chemical_mass": 92528.0, "monoisotopic_mass": 92528.0 }, "refseq": { "ac": "NP_001287388", "name": "uncharacterized protein, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287388" }, "gene_names": [ { "name": "Dmel\\CG15803", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4", "id": "A0A0B4LIC4" }, { "name": "lincRNA.804", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4", "id": "A0A0B4LIC4" }, { "name": "CG15803", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287388", "id": "NP_001287388" }, { "name": "CG15803", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4", "id": "A0A0B4LIC4" }, { "name": "Dmel\\CG15803; lincRNA.804", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287388", "id": "NP_001287388" }, { "name": "Dmel\\CG15803", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4", "id": "A0A0B4LIC4" }, { "name": "Dmel_CG15803", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4", "id": "A0A0B4LIC4" }, { "name": "lincRNA.804", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4", "id": "A0A0B4LIC4" } ], "protein_names": [ { "name": "CG15803-PC", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287388", "id": "NP_001287388" }, { "name": "Uncharacterized protein, isoform C", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIC4/entry#names_and_taxonomy", "id": "A0A0B4LIC4" }, { "name": "uncharacterized protein, isoform C", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287388", "id": "NP_001287388" } ], "function": [], "disease": [ { "disease_id": "DOID:10908", "recommended_name": { "id": "DOID:10908", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head." }, "synonyms": [ { "id": "DOID:10908", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10908", "name": "hydrocephalus, X-linked", "description": "" }, { "id": "DOID:10908", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10908", "name": "hydrocephalus, nonsyndromic, autosomal recessive", "description": "" }, { "id": "MONDO:0007401", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007401", "name": "craniosynostosis-Dandy-Walker malformation-hydrocephalus syndrome", "description": "Craniosynostosis, Dandy-Walker malformation and hydrocephalus is a malformation disorder characterized by sagittal craniosynostosis, Dandy-Walker malformation, hydrocephalus, craniofacial dysmorphism (including dolichocephaly, hypertelorism, micrognathia, positional ear deformity) and variable developmental delay. The inheritance pattern appears to be autosomal dominant." }, { "id": "MONDO:0007401", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007401", "name": "Braddock-Jones-Superneau syndrome", "description": "" }, { "id": "MONDO:0007401", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007401", "name": "craniosynostosis-Dandy-Walker malformation-hydrocephalus syndrome", "description": "" }, { "id": "MONDO:0007401", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007401", "name": "Braddock Jones Superneau syndrome", "description": "" }, { "id": "MONDO:0007401", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007401", "name": "Dandy-Walker malformation with sagittal craniosynostosis and hydrocephalus", "description": "" }, { "id": "MONDO:0007401", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007401", "name": "HDCPH1", "description": "" }, { "id": "MONDO:0007401", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007401", "name": "hydrocephalus, autosomal dominant", "description": "" }, { "id": "MONDO:0007401", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007401", "name": "sagittal craniosynostosis, Dandy-Walker malformation and hydrocephalus", "description": "" }, { "id": "MONDO:0009360", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009360", "name": "hydrocephalus, nonsyndromic, autosomal recessive 1", "description": "Any congenital hydrocephalus in which the cause of the disease is a mutation in the CCDC88C gene." }, { "id": "MONDO:0009360", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009360", "name": "CCDC88C congenital hydrocephalus", "description": "" }, { "id": "MONDO:0009360", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009360", "name": "congenital hydrocephalus caused by mutation in CCDC88C", "description": "" }, { "id": "MONDO:0009360", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009360", "name": "hydrocephalus, congenital, 1", "description": "" }, { "id": "MONDO:0009360", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009360", "name": "hydrocephalus, nonsyndromic, autosomal recessive 1", "description": "" }, { "id": "MONDO:0009360", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009360", "name": "hydrocephalus, nonsyndromic, autosomal recessive type 1", "description": "" }, { "id": "MONDO:0009360", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009360", "name": "HYC1", "description": "" }, { "id": "MONDO:0009360", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009360", "name": "hydrocephaly", "description": "" }, { "id": "MONDO:0009360", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009360", "name": "ventriculomegaly", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "X-linked hydrocephalus with stenosis of the aqueduct of Sylvius", "description": "A form of L1 syndrome caused by changes in the L1CAM gene characterized by severe hydrocephalus mostly with prenatal onset, signs of intracranial hypertension, adducted thumbs, spasticity, and severe intellectual deficit. HSAS represents the severe end of the spectrum and is associated with poor prognosis." }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "Bickers-Adams syndrome", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "HSAS", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "X-linked HSAS", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "X-linked acqueductal stenosis", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "X-linked hydrocephalus", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "X-linked hydrocephalus with stenosis of aqueduct of Sylvius", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "X-linked hydrocephalus with stenosis of the aqueduct of Sylvius", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "hydrocephalus due to aqueductal stenosis, X-linked recessive", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "hydrocephalus with congenital idiopathic intestinal pseudoobstruction, X-linked recessive", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "hydrocephalus with hirschsprung disease, X-linked recessive", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "hydrocephalus with stenosis of the aqueduct of Sylvius", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "HSAS1", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "HYCX", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "XLAS", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "aqueductal stenosis, X-linked", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "hydrocephalus due to congenital stenosis of aqueduct of Sylvius", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "hydrocephalus, X-linked", "description": "" }, { "id": "MONDO:0010611", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010611", "name": "hydrocephalus, X-linked, with congenital idiopathic intestinal pseudoobstruction", "description": "" }, { "id": "MONDO:0009361", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009361", "name": "autosomal recessive hydrocephalus due to congenital stenosis of aqueduct of Sylvius", "description": "" }, { "id": "MONDO:0009361", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009361", "name": "hydrocephalus due to congenital stenosis of aqueduct of Sylvius", "description": "" }, { "id": "MONDO:0009361", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009361", "name": "aqueductal stenosis", "description": "" }, { "id": "MONDO:0014085", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014085", "name": "hydrocephalus, nonsyndromic, autosomal recessive 2", "description": "Any congenital hydrocephalus in which the cause of the disease is a mutation in the MPDZ gene." }, { "id": "MONDO:0014085", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014085", "name": "MPDZ congenital hydrocephalus", "description": "" }, { "id": "MONDO:0014085", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014085", "name": "congenital hydrocephalus caused by mutation in MPDZ", "description": "" }, { "id": "MONDO:0014085", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014085", "name": "hydrocephalus, congenital, 2, with or without brain or eye anomalies", "description": "" }, { "id": "MONDO:0014085", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014085", "name": "hydrocephalus, nonsyndromic, autosomal recessive 2", "description": "" }, { "id": "MONDO:0014085", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014085", "name": "hydrocephalus, nonsyndromic, autosomal recessive type 2", "description": "" }, { "id": "MONDO:0014085", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014085", "name": "HYC2", "description": "" }, { "id": "MIM:236600", "resource": "MIM", "url": "https://www.omim.org/entry/236600", "name": "Hydrocephalus, congenital, 1", "description": "Hydrocephalus, congenital, 1" }, { "id": "MIM:307000", "resource": "MIM", "url": "https://www.omim.org/entry/307000", "name": "Hydrocephalus, congenital, X-linked", "description": "Hydrocephalus, congenital, X-linked" }, { "id": "MIM:615219", "resource": "MIM", "url": "https://www.omim.org/entry/615219", "name": "Hydrocephalus, congenital, 2, with or without brain or eye anomalies", "description": "Hydrocephalus, congenital, 2, with or without brain or eye anomalies" } ], "evidence": [ { "id": "10908", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LIC4", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG15803", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4", "locus": { "chromosome": "3R", "start_pos": 18330932, "end_pos": 18360728, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0038606", "url": "https://www.ensemblgenomes.org/id/FBgn0038606" } ] } } ], "crossref": [ { "id": "A0A0B4LIC4", "url": "https://alphafold.ebi.ac.uk/entry/A0A0B4LIC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0038606", "url": "https://bgee.org/?page=gene&gene_id=FBgn0038606", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00992", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00992", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0038606", "url": "https://flybase.org/reports/FBgn0038606", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "42206", "url": "https://www.ncbi.nlm.nih.gov/gene/42206", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VE88", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VE88*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG15803", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15803", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THIEVVA", "url": "https://omabrowser.org/oma/group/THIEVVA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0B4LIC4", "url": "https://www.orthodb.org/?gene=A0A0B4LIC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q9VE88", "url": "https://www.orthodb.org/?gene=Q9VE88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001287388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287388", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0B4LIC4", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4LIC4-1", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VE88", "url": "https://www.uniprot.org/uniprot/Q9VE88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VE88-1", "url": "https://www.uniprot.org/uniprot/Q9VE88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLSTEWSQVEVIDLINDGNGLGFILVGGRSTGVVIKALTPGGVAERDGRLQLGDHLLQIGEVNLRGFSSEQVATVLRQTGAQVRLIVARPVEPTAIDYQTLACQAPIIPTKLLSDPEELSRHLFQNPSFATAAVAAAAAAAAAAGSGSDGDVGGGGVLDVASLVGLVRGGPAEGTELSAVEPQPSAAVLQLQQLSELAGDLADFPLPPIPGGGGHSMVTDSNAGQRPCPRLDLDIVPFSILSPPPRPALQMLPLETQWRCVQDQNRHIETVIADSKRKLLANEDGGSASASGSGSPDSYMDSPETETYVVELHKNVYGLGITVAGYVCEEEDLSGIFVKSIIEGSAAETSGQIQINDRIVAVDGRSLSGVTNHQAVELLRNTDIVVHLTLERFLRGRKYEHLQVALTEIKGTSAPSGLDRSQDKDQDQESQLSMPGSPSIATLSWLPPKSLDADSIATEGDEAVDAEYVGISGAEDEFIELPSRDTVESNMSHVLDRSDHSGGLTKDQVPRISPIVPLTNGRSLILADDSGNDTDEQCAEPETETAQARKGSKPETERVKDLGDTKTDTDPDPDLDPGQMPTPTNEAPVKAASPTAASLRVAWKSLGISLEGTVDVECGIEKRPHHYIRSILADGPVGRQGILRPGDELLQVNEHKLQGLRHIEVVKILKELPARVKLVCARGTHVPSVINTSQNPEAFETRSLLPGGHQSLQNLLSKAQSESSLYTSSTATLTDAGAAAGGSGGTAGGGARSKSLENVSGLALWSCEVTAVDIEKTEQGFGFSILDYQDPLDSEGSVIVIRGLIRGGAAEATNEIYPGDRLMSVGDRLLQGLELDEAVSILKAMPPGLTRLGICRPLSASDSNSNSNIASPLGDSTST", "length": 880, "header": "tr|A0A0B4LIC4-1|A0A0B4LIC4_DROME Isoform 1 of Uncharacterized protein, isoform C OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15803 PE=4 SV=1 CANONICAL=A0A0B4LIC4-1" }, "isoforms": [ { "isoform_ac": "A0A0B4LIC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIC4/entry#A0A0B4LIC4-1", "sequence": { "sequence": "MVLSTEWSQVEVIDLINDGNGLGFILVGGRSTGVVIKALTPGGVAERDGRLQLGDHLLQIGEVNLRGFSSEQVATVLRQTGAQVRLIVARPVEPTAIDYQTLACQAPIIPTKLLSDPEELSRHLFQNPSFATAAVAAAAAAAAAAGSGSDGDVGGGGVLDVASLVGLVRGGPAEGTELSAVEPQPSAAVLQLQQLSELAGDLADFPLPPIPGGGGHSMVTDSNAGQRPCPRLDLDIVPFSILSPPPRPALQMLPLETQWRCVQDQNRHIETVIADSKRKLLANEDGGSASASGSGSPDSYMDSPETETYVVELHKNVYGLGITVAGYVCEEEDLSGIFVKSIIEGSAAETSGQIQINDRIVAVDGRSLSGVTNHQAVELLRNTDIVVHLTLERFLRGRKYEHLQVALTEIKGTSAPSGLDRSQDKDQDQESQLSMPGSPSIATLSWLPPKSLDADSIATEGDEAVDAEYVGISGAEDEFIELPSRDTVESNMSHVLDRSDHSGGLTKDQVPRISPIVPLTNGRSLILADDSGNDTDEQCAEPETETAQARKGSKPETERVKDLGDTKTDTDPDPDLDPGQMPTPTNEAPVKAASPTAASLRVAWKSLGISLEGTVDVECGIEKRPHHYIRSILADGPVGRQGILRPGDELLQVNEHKLQGLRHIEVVKILKELPARVKLVCARGTHVPSVINTSQNPEAFETRSLLPGGHQSLQNLLSKAQSESSLYTSSTATLTDAGAAAGGSGGTAGGGARSKSLENVSGLALWSCEVTAVDIEKTEQGFGFSILDYQDPLDSEGSVIVIRGLIRGGAAEATNEIYPGDRLMSVGDRLLQGLELDEAVSILKAMPPGLTRLGICRPLSASDSNSNSNIASPLGDSTST", "length": 880, "header": "tr|A0A0B4LIC4-1|A0A0B4LIC4_DROME Isoform 1 of Uncharacterized protein, isoform C OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15803 PE=4 SV=1 CANONICAL=A0A0B4LIC4-1" }, "locus": { "chromosome": "3R", "start_pos": 18355527, "end_pos": 18352837, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0345256", "url": "https://www.ensemblgenomes.org/id/FBtr0345256" }, { "database": "Ensembl Peptide", "id": "FBpp0311433", "url": "https://www.ensemblgenomes.org/id/FBpp0311433" } ] } }, { "isoform_ac": "Q9VE88-1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIC4/entry#Q9VE88-1", "sequence": { "sequence": "MVLSTEWSQVEVIDLINDGNGLGFILVGGRSTGVVIKALTPGGVAERDGRLQLGDHLLQIGEVNLRGFSSEQVATVLRQTGAQVRLIVARPVEPTAIDYQTLACQAPIIPTKLLSDPEELSRHLFQNPSFATAAVAAAAAAAAAAGSGSDGDVGGGGVLDVASLVGLVRGGPAEGTELSAVEPQPSAAVLQLQQLSELAGDLADFPLPPIPGGGGHSMVTDSNAGQRPCPRLDLDIVPFSILSPPPRPALQMLPLETQWRCVQDQNRHIETVIADSKRKLLANEDGGSASASGSGSPDSYMDSPETETYVVELHKNVYGLGITVAGYVCEEEDLSGIFVKSIIEGSAAETSGQIQINDRIVAVDGRSLSGVTNHQAVELLRNTDIVVHLTLERFLRGRKYEHLQVALTEIKGTSAPSGLDRSQDKDQDQESQLSMPGSPSIATLSWLPPKSLDADSIATEGDEAVDAEYVGISGAEDEFIELPSRDTVESNMSHVLDRSDHSGGLTKDQVPRISPIVPLTNGRSLILADDSGNDTDEQCAEPETETAQARKGSKPETERVKDLGDTKTDTDPDPDLDPGQMPTPTNEAPVKAASPTAASLRVAWKRISLEGTVDVECGIEKRPHHYIRSILADGPVGRQGILRPGDELLQVNEHKLQGLRHIEVVKILKELPARVKLVCARGTHVPSVINTSQNPEAFETRSLLPGGHQSLQNLLSKAQSESSLYTSSTATLTDAGAAAGGSGGTAGGGARSKSLENVSGLALWSCEVTAVDIEKTEQGFGFSILDYQDPLDSEGSVIVIRGLIRGGAAEATNEIYPGDRLMSVGDRLLQGLELDEAVSILKAMPPGLTRLGICRPLSASDSNSNSNIASPLGDSTST", "length": 878, "header": "tr|Q9VE88-1|A0A0B4LIC4_DROME Computationally mapped isoform of Uncharacterized protein, isoform C OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15803 PE=4 SV=3 CANONICAL=A0A0B4LIC4-1" }, "locus": { "chromosome": "3R", "start_pos": 18355527, "end_pos": 18352837, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0302308", "url": "https://www.ensemblgenomes.org/id/FBtr0302308" }, { "database": "Ensembl Peptide", "id": "FBpp0291514", "url": "https://www.ensemblgenomes.org/id/FBpp0291514" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 596, "start_aa": "T", "end_pos": 596, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr596", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VE88", "url": "https://www.uniprot.org/uniprot/Q9VE88" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VE88", "url": "https://www.uniprot.org/uniprot/Q9VE88" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VE88", "url": "https://www.uniprot.org/uniprot/Q9VE88" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VE88", "url": "https://www.uniprot.org/uniprot/Q9VE88" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VE88", "url": "https://www.uniprot.org/uniprot/Q9VE88" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VE88", "url": "https://www.uniprot.org/uniprot/Q9VE88" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VE88", "url": "https://www.uniprot.org/uniprot/Q9VE88" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VE88", "url": "https://www.uniprot.org/uniprot/Q9VE88" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15803", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15803", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LIC4", "url": "https://www.uniprot.org/uniprot/A0A0B4LIC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A0B4LIC4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 880, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0B4LIC4-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 596 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 491, "end_pos": 493 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 692, "end_pos": 694 }, { "start_pos": 759, "end_pos": 761 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }