{ "uniprot_canonical_ac": "A0A096MJQ2-1", "uniprot_ac": "A0A096MJQ2", "uniprot_id": "A0A096MJQ2_RAT", "mass": { "chemical_mass": 34592.0, "monoisotopic_mass": 34592.0 }, "refseq": {}, "gene_names": [ { "name": "Selenov", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A096MJQ2", "id": "A0A096MJQ2" }, { "name": "Selv", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A096MJQ2", "id": "A0A096MJQ2" } ], "protein_names": [ { "name": "Selenoprotein V", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A096MJQ2/entry#names_and_taxonomy", "id": "A0A096MJQ2" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A096MJQ2", "url": "https://www.uniprot.org/uniprot/A0A096MJQ2" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Selenov", "url": "https://www.uniprot.org/uniprot/A0A096MJQ2", "locus": { "chromosome": "1", "start_pos": 83551473, "end_pos": 83558756, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000051208", "url": "https://www.ensembl.org/id/ENSRNOG00000051208" } ] } } ], "crossref": [ { "id": "A0A096MJQ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A096MJQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSRNOG00000051208", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000051208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR011893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HPVPLEW", "url": "https://omabrowser.org/oma/group/HPVPLEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15124", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15124", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15124:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15124:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10262", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10262", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "1562943", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1562943", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A096MJQ2", "url": "https://www.uniprot.org/uniprot/A0A096MJQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A096MJQ2-1", "url": "https://www.uniprot.org/uniprot/A0A096MJQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2JXK3", "url": "https://www.uniprot.org/uniprot/A0A0G2JXK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2JXK3-1", "url": "https://www.uniprot.org/uniprot/A0A0G2JXK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNKARNPAPSSVRANTPSRTPTPVRTATPVRASTPAHNRSPVRTSIRVRTPANPVPIRFPTPAPAPAPTPTPAPTPAPVPAAAPVRTPAPVRASIQGRSFPTISPVRFLRNLALPAAQPLSSGGAGSLSKDLTLAQKQKPSIHSLAEAIQGPFPVLTPSASSETHGSIPDPAPPTDSLASTAMASSTLDPIPGPKPTLEFLASPLKETPDLGKLSTISPAQNFVSTKEVPSTSEDVPTANRILIRVMYCITPSLPSQYILLKKTLEHQFPNLLEFEEERATQVTGEFEVFVDGKLIHSKKKGDGFVDETSLKKLVGAIDEEIKKR", "length": 326, "header": "tr|A0A096MJQ2-1|A0A096MJQ2_RAT Isoform 1 of Selenoprotein V OS=Rattus norvegicus OX=10116 GN=Selenov PE=4 SV=2 CANONICAL=A0A096MJQ2-1" }, "isoforms": [ { "isoform_ac": "A0A096MJQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A096MJQ2/entry#A0A096MJQ2-1", "sequence": { "sequence": "MNNKARNPAPSSVRANTPSRTPTPVRTATPVRASTPAHNRSPVRTSIRVRTPANPVPIRFPTPAPAPAPTPTPAPTPAPVPAAAPVRTPAPVRASIQGRSFPTISPVRFLRNLALPAAQPLSSGGAGSLSKDLTLAQKQKPSIHSLAEAIQGPFPVLTPSASSETHGSIPDPAPPTDSLASTAMASSTLDPIPGPKPTLEFLASPLKETPDLGKLSTISPAQNFVSTKEVPSTSEDVPTANRILIRVMYCITPSLPSQYILLKKTLEHQFPNLLEFEEERATQVTGEFEVFVDGKLIHSKKKGDGFVDETSLKKLVGAIDEEIKKR", "length": 326, "header": "tr|A0A096MJQ2-1|A0A096MJQ2_RAT Isoform 1 of Selenoprotein V OS=Rattus norvegicus OX=10116 GN=Selenov PE=4 SV=2 CANONICAL=A0A096MJQ2-1" }, "locus": { "chromosome": "1", "start_pos": 83558704, "end_pos": 83555627, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000076809.3", "url": "https://www.ensembl.org/id/ENSRNOT00000076809.3" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000068219.2", "url": "https://www.ensembl.org/id/ENSRNOP00000068219.2" } ] } }, { "isoform_ac": "A0A0G2JXK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A096MJQ2/entry#A0A0G2JXK3-1", "sequence": { "sequence": "MNNKARNPAPSSVRANTPSRTPTPVRTATPVRASTPAHNRSPVRTSIRVRTPANPVPIRFPTPAPAPAPTPTPAPTPAPVPAAAPVRTPAPVRASIQGRSFPTISPVRFLRNLALPAAQPLSSGGAGSLSKDLTLAQKQKPSIHSLAEAIQGPFPVLTPSASSETHGSIPDPAPPTDSLASTAMASSTLDPIPGPKPTLEFLASPLKETPDLGKLSTISPAQNFVSTKEVPSTSEDVPTANRILIRVMYCGLSYGLRYILLKKTLEHQFPNLLEFEEERATQVTGEFEVFVDGKLIHSKKKGDGFVDETSLKKLVGAIDEEIKKR", "length": 325, "header": "tr|A0A0G2JXK3-1|A0A096MJQ2_RAT Computationally mapped isoform of Selenoprotein V OS=Rattus norvegicus OX=10116 GN=Selenov PE=4 SV=1 CANONICAL=A0A096MJQ2-1" }, "locus": { "chromosome": "1", "start_pos": 83558704, "end_pos": 83555627, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000087175.2", "url": "https://www.ensembl.org/id/ENSRNOT00000087175.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000070306.1", "url": "https://www.ensembl.org/id/ENSRNOP00000070306.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 70, "start_aa": "T", "end_pos": 70, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 72, "start_aa": "T", "end_pos": 72, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr72", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 76, "start_aa": "T", "end_pos": 76, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr76", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BHQ2-1", "protein_name": "Selenoprotein V", "gene_name": "SELENOV", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNNQPRTPAPTPARASTPVRGSTLHRTSIQVRTPTPGPDSGPTRITTLLRTPALIRTLTPIRTPTPVRTPTPVPPSTPVRSPIPVRTPTPVPPSTPVRTPTPVPLSTPVRPPTPVRPPTPVRPPTPVRPPTPIGTPTLIRSPTPVQIPIPEPIPTPIPSRVLIPPLESFPDSALPSGPPLELEPTLTVSPAKNLEPSPAKNLEPSPRVKQVSSAANGFPPIQEPLPALTPLATDLRSPSLGSPLRTDTSTTNLIASSSGHVPGTPILGAIQAILPVPATALASISGNLKEENKIMIRVVYCGIFVSMTRYILLRKSLEQQFPNSLIFEEEISAQATGEFEVFVDGKLIHSKKNGDGFVDEVKLQTIVNLLNEEFKKKVAGN", "length": 381 }, "evidence": [ { "id": "A0A096MJQ2", "url": "https://omabrowser.org/oma/group/A0A096MJQ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P59797-1", "protein_name": "Selenoprotein V", "gene_name": "SELENOV", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNNQARTPAPSSARTSTSVRASTPTRTPTPLRTPTPVRTRTPIRTLTPVLTPSPAGTSPLVLTPAPAQIPTLVPTPALARIPRLVPPPAPAWIPTPVPTPVPVRNPTPVPTPARTLTPPVRVPAPAPAQLLAGIRAALPVLDSYLAPALPLDPPPEPAPELPLLPEEDPEPAPSLKLIPSVSSEAGPAPGPLPTRTPLAANSPGPTLDFTFRADPSAIGLADPPIPSPVPSPILGTIPSAISLQNCTETFPSSSENFALDKRVLIRVTYCGLUSYSLRYILLKKSLEQQFPNHLLFEEDRAAQATGEFEVFVNGRLVHSKKRGDGFVNESRLQKIVSVIDEEIKKR", "length": 346 }, "evidence": [ { "id": "A0A096MJQ2", "url": "https://omabrowser.org/oma/group/A0A096MJQ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7JQV9-1", "protein_name": "RE04224p", "gene_name": "CG10953-PA", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKFLVVAFAVLACAYGDVSHLGYDYSPPAPAPVYQPAPAPVYQPAPAPVYQPAPAPVVIPAPAPAPVVIPAPAPAPVVIPAPAPVKTYVPPAPISIPAPVYQPAPAPIRIPAPVYQPAPAPISIPAPAPIEIPAPAPVNTYIPPAPAPAPVYQPAPAPIPVSIPAPAPVYQPAPAPVVIPAPAPAPVVIPAPAPAPVVIPAPAPVKSYVPPAPISIPAPAPVYQPAPISIPAPAPVYQPAPAPVYQPTNTQVLEEIEPASNDGYRYKTVRRRVYRHRF", "length": 278 }, "evidence": [ { "id": "A0A096MJQ2", "url": "https://omabrowser.org/oma/group/A0A096MJQ2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to selenium ion", "id": "GO:0010269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010269", "evidence": [ { "database": "UniProtKB", "id": "A0A096MJQ2", "url": "https://www.uniprot.org/uniprot/A0A096MJQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A096MJQ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 326, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A096MJQ2-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 70, 72, 76 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 3 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 3 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }