{ "uniprot_canonical_ac": "A0A096MJF9-1", "uniprot_ac": "A0A096MJF9", "uniprot_id": "A0A096MJF9_RAT", "mass": { "chemical_mass": 116387.0, "monoisotopic_mass": 116387.0 }, "refseq": { "ac": "XP_008766187", "name": "transmembrane protein 132E precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008766187" }, "gene_names": [ { "name": "Tmem132e", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A096MJF9", "id": "A0A096MJF9" }, { "name": "RGD1565522", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008766187", "id": "XP_008766187" }, { "name": "Tmem132e", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008766187", "id": "XP_008766187" } ], "protein_names": [ { "name": "Transmembrane protein 132E", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A096MJF9/entry#names_and_taxonomy", "id": "A0A096MJF9" }, { "name": "transmembrane protein 132E precursor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008766187", "id": "XP_008766187" } ], "function": [], "disease": [ { "disease_id": "DOID:0111634", "recommended_name": { "id": "DOID:0111634", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111634", "name": "autosomal recessive nonsyndromic deafness 99", "description": "An autosomal recessive nonsyndromic deafness characterized by prelingual, severe to profound sensorineural hearing loss without vestibular dysfunction that has_material_basis_in homozygous or compound heterozygous mutation in the TMEM132E gene on chromosome 17q12." }, "synonyms": [ { "id": "DOID:0111634", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111634", "name": "DFNB99", "description": "" }, { "id": "DOID:0111634", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111634", "name": "autosomal recessive deafness 99", "description": "" }, { "id": "MONDO:0032776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032776", "name": "hearing loss, autosomal recessive 99", "description": "" }, { "id": "MONDO:0032776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032776", "name": "DFNB99", "description": "" }, { "id": "MONDO:0032776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032776", "name": "deafness, autosomal recessive 99", "description": "" }, { "id": "MIM:618481", "resource": "MIM", "url": "https://www.omim.org/entry/618481", "name": "Deafness, autosomal recessive, 99", "description": "Deafness, autosomal recessive, 99" } ], "evidence": [ { "id": "0111634", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0111634" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A096MJF9", "url": "https://www.uniprot.org/uniprot/A0A096MJF9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Tmem132e", "url": "https://www.uniprot.org/uniprot/A0A096MJF9", "locus": { "chromosome": "10", "start_pos": 67386789, "end_pos": 67330751, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000007455", "url": "https://www.ensembl.org/id/ENSRNOG00000007455" } ] } } ], "crossref": [ { "id": "A0A096MJF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A096MJF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSRNOG00000007455", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000007455", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GEMVPRR", "url": "https://omabrowser.org/oma/group/GEMVPRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A096MJF9", "url": "https://www.orthodb.org/?gene=A0A096MJF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "D4A2A3", "url": "https://www.orthodb.org/?gene=D4A2A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13388:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13388:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15705", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF15706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15706", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF16070", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16070", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_008766187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008766187", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1565522", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1565522", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A096MJF9", "url": "https://www.uniprot.org/uniprot/A0A096MJF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A096MJF9-1", "url": "https://www.uniprot.org/uniprot/A0A096MJF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D4A2A3", "url": "https://www.uniprot.org/uniprot/D4A2A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D4A2A3-1", "url": "https://www.uniprot.org/uniprot/D4A2A3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGMLGRRGAALLCLSVLLAHAASRSHPASPSPPGPQASPVLPVSYRLSHTRLAFFLKEARPPTPTAMNGSLQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPSSTLDIPERLTVNWKVRAFIVRARVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVRSSCRLGGALATCLVRAELPLAWFGPPAPAAPPSTRRKSPDGLEPEATAESQQVELYYTLHAPDAAGGCGSARRGSGPGPAARAESPTQHPLLRIGSISLFRPPPRRAMQEHRLDSNLMIRLPDRPLRPGEVLSILLYLAPNSSSAASPSLEHFTLRVKAKKGVTLLGTKSRNGQWHVTSELLTGAKHSTATVDVAWAQGTPLPPWESQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHSALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGVVLDVSDLVECQSHREDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLSAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSARESEDEEEEEEERRQSANRGCTLQYQHATLQVFTQFHTTSSEGTEQVVTMLGPDWLVEVTDLVSDFMRVGDPRVAHLVDSNTLAGLEPGTTPFKVVSPLTEAVLGETLLTVTEEKVSITQLQAQVVASLTLSLRPSPGSSHTILATTAAQPTLSSVKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVNSLDERVATVTQDKAFPLLVAEAEGAGDLLRAELTISESCQKTKRKSVLATTPVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGAGPPGTAIPAGEVPGLGTAGPMPPTEDFLPLPTGFLQMPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPAGSALETVPACCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSARDQTEDPASSPTSKRKRVKFTTFTTLPSEELAYDSVPAGEEDEEDEEDLGWGCPDVAGTTRPTPPPDLHNYMRRIKDIA", "length": 1073, "header": "tr|A0A096MJF9-1|A0A096MJF9_RAT Isoform 1 of Transmembrane protein 132E OS=Rattus norvegicus OX=10116 GN=Tmem132e PE=3 SV=1 CANONICAL=A0A096MJF9-1" }, "isoforms": [ { "isoform_ac": "A0A096MJF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A096MJF9/entry#A0A096MJF9-1", "sequence": { "sequence": "MAPGMLGRRGAALLCLSVLLAHAASRSHPASPSPPGPQASPVLPVSYRLSHTRLAFFLKEARPPTPTAMNGSLQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPSSTLDIPERLTVNWKVRAFIVRARVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVRSSCRLGGALATCLVRAELPLAWFGPPAPAAPPSTRRKSPDGLEPEATAESQQVELYYTLHAPDAAGGCGSARRGSGPGPAARAESPTQHPLLRIGSISLFRPPPRRAMQEHRLDSNLMIRLPDRPLRPGEVLSILLYLAPNSSSAASPSLEHFTLRVKAKKGVTLLGTKSRNGQWHVTSELLTGAKHSTATVDVAWAQGTPLPPWESQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHSALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGVVLDVSDLVECQSHREDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLSAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSARESEDEEEEEEERRQSANRGCTLQYQHATLQVFTQFHTTSSEGTEQVVTMLGPDWLVEVTDLVSDFMRVGDPRVAHLVDSNTLAGLEPGTTPFKVVSPLTEAVLGETLLTVTEEKVSITQLQAQVVASLTLSLRPSPGSSHTILATTAAQPTLSSVKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVNSLDERVATVTQDKAFPLLVAEAEGAGDLLRAELTISESCQKTKRKSVLATTPVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGAGPPGTAIPAGEVPGLGTAGPMPPTEDFLPLPTGFLQMPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPAGSALETVPACCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSARDQTEDPASSPTSKRKRVKFTTFTTLPSEELAYDSVPAGEEDEEDEEDLGWGCPDVAGTTRPTPPPDLHNYMRRIKDIA", "length": 1073, "header": "tr|A0A096MJF9-1|A0A096MJF9_RAT Isoform 1 of Transmembrane protein 132E OS=Rattus norvegicus OX=10116 GN=Tmem132e PE=3 SV=1 CANONICAL=A0A096MJF9-1" }, "locus": { "chromosome": "10", "start_pos": 67385783, "end_pos": 67330992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000076773.2", "url": "https://www.ensembl.org/id/ENSRNOT00000076773.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000068114.1", "url": "https://www.ensembl.org/id/ENSRNOP00000068114.1" } ] } }, { "isoform_ac": "D4A2A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A096MJF9/entry#D4A2A3-1", "sequence": { "sequence": "MAPGMLGRRGAALLCLSVLLAHAASRSHPASPSPPGPQASPVLPVSYRLSHTRLAFFLKEARPPTPTAMNGSLQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPSSTLDIPERLTVNWKVRAFIVRARVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREHPLLRIGSISLFRPPPRRAMQEHRLDSNLMIRLPDRPLRPGEVLSILLYLAPNSSSAASPSLEHFTLRVKAKKGVTLLGTKSRNGQWHVTSELLTGAKHSTATVDVAWAQGTPLPPWESQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHSALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGVVLDVSDLVECQSHREDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLSAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSARESEDEEEEEEERRQSANRGCTLQYQHATLQVFTQFHTTSSEGTEQVVTMLGPDWLVEVTDLVSDFMRVGDPRVAHLVDSNTLAGLEPGTTPFKVVSPLTEAVLGETLLTVTEEKVSITQLQAQVVASLTLSLRPSPGSSHTILATTAAQPTLSSVKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVNSLDERVATVTQDKAFPLLVAEAEGAGDLLRAELTISESCQKTKRKSVLATTPVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGAGPPGTAIPAGEVPGLGTAGPMPPTEDFLPLPTGFLQMPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPAGSALETVPACCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSARDQTEDPASSPTSKRKRVKFTTFTTLPSEELAYDSVPAGEEDEEDEEDLGWGCPDVAGTTRPTPPPDLHNYMRRIKDIA", "length": 983, "header": "tr|D4A2A3-1|D4A2A3_RAT Computationally mapped isoform of Transmembrane protein 132E OS=Rattus norvegicus OX=10116 GN=Tmem132e PE=3 SV=1 CANONICAL=A0A096MJF9-1" }, "locus": { "chromosome": "10", "start_pos": 67385783, "end_pos": 67330992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000055999.5", "url": "https://www.ensembl.org/id/ENSRNOT00000055999.5" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000052853.2", "url": "https://www.ensembl.org/id/ENSRNOP00000052853.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 1057, "start_aa": "T", "end_pos": 1057, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr1057", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 67, "start_aa": "T", "end_pos": 67, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr67", "evidence": [ { "id": "GLY_001157", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001157" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LQS0-1", "protein_name": "Transmembrane protein 132E", "gene_name": "TMEM132E", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPGMPGRGGAALLCLSALLAHASGRSHPASPSPPGPQASPVLPISYRLSHTRLAFFLREARPPPPTVANGSLQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPSSTLDIPERLTVSWKVRAFIVHSRVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVKSSCRLSGGLATCLVRAELPLAWFGPPAPAAPPSARRKSPDGLEPEATGESQQAELYYTLHAPDASGGCGGTRRGAGPGVGARAESPTQHPLLRIGSISLFRPPPRRTLQEHRLDSNLMIRLPDRPLKPGEVLSIVLYLAPNSSSPSSPSLEHFTLRVKAKKGVTLLGTKSRSGQWHVTSELLTGAKHSTATVDVSWAQGTPLPPWEGQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHGALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGLVLDVSALVECESDNEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLNAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSARESEDEDEEEERPQSASRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVARMVDSSTLAGLEPGTTPFKVVSPLTESVLGETLLTVTEEKVSITQLQAQVVASLALSLRPSPGSSHTILATAAAQQTLSFLKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVSSLDERVATVTQDRAFPLVVAEAEGAGELLRAELTIAESCQKTKRKSVLATTRVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGAGPPGTAGPRPEAAGPGTASPAVPPTEDFLPLPTGFLQMPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPASNPMETVPACCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSARDQAEDPASSPTSKRKRVKFTTFTTLPSEELAYDSVPAGEEDEEDEEDLGWGCPDVTGTTRPAPPPDLHNYMRRIKEIA", "length": 1073 }, "evidence": [ { "id": "A0A096MJF9", "url": "https://omabrowser.org/oma/group/A0A096MJF9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1P195-1", "protein_name": "Transmembrane protein 132E", "gene_name": "TMEM132E", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGSPEKMLPGPAALICCLCSLLLPAQAKGPAPSPEPSEPPGAAMLPVSYRLSNTRLAFFLKEVGASPPANSSTPLQRAEPFVVFQTKELPVLNVTLGPFSTGLVLPKEHLQPSSTLEVPNRLTVNWKVRAFIIQPRLVANQPVVQVLFYVAGRDWDDFDVTDRLPCVRLHAFRDAREIKSSCRLRGSLATCLVQAELPHAWFRPAAVPLGRRKGPDSMEVPGESQQVELYYTLHAPDGAGQCLGDTSVSSPRRGTGGARTEGPTQHPLLRIGSVSLLQPPPAQPMQEHRLDGNVFIRLPDRPLKPGEVLSILLYLMSNSTVEHFTLRVKAKKGVNLLSTKSRSRQWLVSSELLTGGKHSTATVDVARVEGAGPRDGESSSEIMQLDFEMENFTSQSVTRRIMWHIDYRGRNPPPDLEKVVTELTVIQRDIRAIVPLAMDTEIINTAILTGRTVAIPVKVIAIELSGVIVDVSAMVECKSNNEDIIKVSSSCDYVFVSGKESRGSMSARVTFTYEHLSAPLEMTVWVPKLPLHIELSDSRLSQVKGWRVPILPDRRSVRDSEHEEDEEERKQSRGCALQYQHATLQVFTQFHTTAAEGTGQVVTMLGPDWLVEVTDLVSDFMRVDDPRVAHLVDSFTLAGREPGTTLFKVVSPLMEAVLGETLVTVAEEKVSITDLKAQVVSSLSLSLHPSPGNSHTIIARTAAQQTLSFLKQEALLSLWISYSDGTTAPLSLYDPKDYNLVVSSLDEKVVTVTQDRAFPLVVAESEGAGELLRAELVICESCQKTKRKSVLFTALASVRVHFGSEEDPTYDYDHVPSRPGLETGSSTTLRAEVERKAEPSEDSRMPSASHPTEDFPTIPTGFVQVTRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLKYRHKRIPPEGQTNMDHSHHWVFLGNGQPLRAHNDLSPQPESPGNPLENVQTCCHADHHSSGSSQTSVQSQVHGRGDGSSGGSTRDQSEDPLNSPTSKRKRVKFTTFATLPTDELAYNSIPIADEEDLEWVCQDMGLQDPEELHNYIRRIKEIA", "length": 1053 }, "evidence": [ { "id": "A0A096MJF9", "url": "https://omabrowser.org/oma/group/A0A096MJF9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6IEE6-1", "protein_name": "Transmembrane protein 132E", "gene_name": "Tmem132e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPGMSGRRGAALLCLSVLLAHAASRSHPASPSPPGTQASPILPVSYRLSHTRLAFFLKEARPLTPAAINGSLQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPSSTLDIPERLTVNWKVRAFIVRARVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVRSSCRLGGALATCLVRAELPLAWFGPPAPAAPPSARRKSPDGLEPEAAAESQQVELYYTLHAPDASGGCGSARRGPGPGPGAAARAESPTQHPLLRIGSISLFRPPPRRAVQEHRLDSNLMIRLPDRPLRPGEVLSILLYLAPNSSSAASPSVEHFTLRVKAKKGVTLLGTKSRSGQWRVTSELLTGAKHSTATVDVAWALDTPLPPWEGQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHSALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGLVLDVSDLVECQSHSEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLSAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSARESEDEEEEEEERRQSANRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVAHLVDSNTLAGLEPGTTPFKVVSPLTEAVLGETLLTVTEEKVSITQLQAQVVASLTLSLRPSPGSSHTILATTAAQPTLSLVKQEALLSLWLSYSDGTTAPLSLYSSRDYGLLVSSLDERVATVTQDKAFPLVVAEAEGSGDLLRAELTISESCQKTKRKSVLATTPVSLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGAGPPGTAIPAGEVPGLGTAGPVPPTEDYLPLPTGFLQMPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPAGSALETVPACCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSARDQTEDPASSPTSKRKRVKFTTFTTLPTEELAYDSVPAGEEEDEEEDLGWGCPDVAGTTRPTPPPDLHNYMRRIKDIA", "length": 1074 }, "evidence": [ { "id": "A0A096MJF9", "url": "https://omabrowser.org/oma/group/A0A096MJF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6IEE7-1", "protein_name": "Transmembrane protein 132E", "gene_name": "TMEM132E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPGMSGRGGAALLCLSALLAHASGRSHPASPSPPGPQASPVLPVSYRLSHTRLAFFLREARPPSPAVANSSLQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPSSTLDIPERLTVNWKVRAFIVRSHVPASQPVVQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVKSSCRLSGGLATCLVRAELPLAWFGPPAPAAPPTARRKSPDGLEPEATGESQQAELYYTLHAPDASGGCGGSRRGAGPGVGARAESPTQHPLLRIGSISLFRPPPRRTLQEHRLDSNLMIRLPDRPLKPGEVLSILLYLAPNSSSPSSPSVEHFTLRVKAKKGVTLLGTKSRSGQWHVTSELLTGAKHSTATVDVAWAQSTPLPPREGQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHGALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVNGLVLDISALVECESDNEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLNAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSVRESEDEDEEEEERRQSASRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVAHMVDSSTLAGLEPGTTPFKVVSPLTEAVLGETLLTVTEEKVSITQLQAQVVASLALSLRPSPGSSHTILATTAAQQTLSFLKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVSSLDEHVATVTQDRAFPLVVAEAEGSGELLRAELTIAESCQKTKRKSVLATTPVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGAGPPGSALPAPEAPGPGTASPVVPPTEDFLPLPTGFLQVPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPAGNPLETVPAFCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSARDQAEDPASSPTSKRKRVKFTTFTTLPSEELAYDSVPAGEEDEEEEEDLGWGCPDVAGPTRPTAPPDLHNYMRRIKEIA", "length": 1074 }, "evidence": [ { "id": "A0A096MJF9", "url": "https://omabrowser.org/oma/group/A0A096MJF9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A096MJF9", "url": "https://www.uniprot.org/uniprot/A0A096MJF9" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A096MJF9", "url": "https://www.uniprot.org/uniprot/A0A096MJF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "posterior lateral line neuromast hair cell development", "id": "GO:0035677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035677", "evidence": [ { "database": "UniProtKB", "id": "A0A096MJF9", "url": "https://www.uniprot.org/uniprot/A0A096MJF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A096MJF9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1073, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A096MJF9-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 67, 1057 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 318, "end_pos": 320 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 91, "end_pos": 93 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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