{
    "uniprot_canonical_ac": "A0A087WS15-1",
    "uniprot_ac": "A0A087WS15",
    "uniprot_id": "A0A087WS15_MOUSE",
    "mass": {
        "chemical_mass": 58533.0,
        "monoisotopic_mass": 58533.0
    },
    "refseq": {
        "ac": "NP_001093655",
        "name": "cytochrome P450, family 4, subfamily a, polypeptide 30b",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093655"
    },
    "gene_names": [
        {
            "name": "Cyp4a30b",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A087WS15",
            "id": "A0A087WS15"
        },
        {
            "name": "Cyp4a30b-ps",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093655",
            "id": "NP_001093655"
        },
        {
            "name": "Cyp4a30b",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093655",
            "id": "NP_001093655"
        }
    ],
    "protein_names": [
        {
            "name": "Cytochrome P450, family 4, subfamily a, polypeptide 30b",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A087WS15/entry#names_and_taxonomy",
            "id": "A0A087WS15"
        },
        {
            "name": "cytochrome P450, family 4, subfamily a, polypeptide 30b, pseudogene",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093655",
            "id": "NP_001093655"
        },
        {
            "name": "cytochrome P450, family 4, subfamily a, polypeptide 30b",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093655",
            "id": "NP_001093655"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0110861",
            "recommended_name": {
                "id": "DOID:0110861",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0110861",
                "name": "autosomal recessive polycystic kidney disease",
                "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion."
            },
            "synonyms": [
                {
                    "id": "DOID:0110861",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110861",
                    "name": "Arpkd",
                    "description": ""
                },
                {
                    "id": "DOID:0110861",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110861",
                    "name": "Pkhd1",
                    "description": ""
                },
                {
                    "id": "DOID:0110861",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110861",
                    "name": "Polycystic Kidney Disease, Infantile, Type I",
                    "description": ""
                },
                {
                    "id": "DOID:0110861",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110861",
                    "name": "Polycystic Kidney and Hepatic Disease 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "polycystic kidney disease 4",
                    "description": "A autosomal dominant polycystic kidney disease that has material basis in mutation in the PKD4 gene."
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "polycystic kidney disease 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "polycystic kidney disease 4, with or without hepatic disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "PKD3",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "PKD3, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "PKD4",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "hepatic fibrosis, congenital",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "polycystic kidney and hepatic disease 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "polycystic kidney disease 4 with or without hepatic disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "polycystic kidney disease 4 with or without polycystic liver disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "polycystic kidney disease, autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0033004",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004",
                    "name": "polycystic kidney disease, infantile, type 1",
                    "description": ""
                },
                {
                    "id": "MIM:263200",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/263200",
                    "name": "Polycystic kidney disease 4, with or without polycystic liver disease",
                    "description": "Polycystic kidney disease 4, with or without polycystic liver disease"
                }
            ],
            "evidence": [
                {
                    "id": "0110861",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110861"
                }
            ]
        },
        {
            "disease_id": "DOID:10763",
            "recommended_name": {
                "id": "DOID:10763",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10763",
                "name": "hypertension",
                "description": "An artery disease characterized by chronic elevated blood pressure in the arteries."
            },
            "synonyms": [
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "HTN",
                    "description": ""
                },
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "hyperpiesia",
                    "description": ""
                },
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "vascular hypertensive disorder",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "10763",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10763"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A087WS15",
                    "url": "https://www.uniprot.org/uniprot/A0A087WS15"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
    "gene": [
        {
            "name": "Cyp4a30b",
            "url": "https://www.uniprot.org/uniprot/A0A087WS15",
            "locus": {
                "chromosome": "4",
                "start_pos": 115328259,
                "end_pos": 115309801,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000084346",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000084346"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "A0A087WS15",
            "url": "https://alphafold.ebi.ac.uk/entry/A0A087WS15",
            "database": "AlphaFoldDB",
            "categories": []
        },
        {
            "id": "ENSMUSG00000084346",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000084346",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd20678",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20678",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "435802",
            "url": "https://www.ncbi.nlm.nih.gov/gene/435802",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001128",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR002401",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017972",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036396",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR050196",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR050196",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:435802",
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:435802",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "3717145",
            "url": "http://www.informatics.jax.org/marker/MGI:3717145",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "EDQKWAK",
            "url": "https://omabrowser.org/oma/group/EDQKWAK/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A087WS15",
            "url": "https://www.orthodb.org/?gene=A0A087WS15",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24291",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24291",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24291:SF47",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24291:SF47",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00067",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-211935",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211935",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-211958",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211958",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-211979",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211979",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-2142691",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2142691",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001093655",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093655",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A087WS15",
            "url": "https://www.uniprot.org/uniprot/A0A087WS15",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A087WS15-1",
            "url": "https://www.uniprot.org/uniprot/A0A087WS15-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSIFELSHITNVFGIFGLLQVVSLLGLLLLLLKSAQYYLHRQWLIKSLQQFPPAPPPQWLFGNTLKDQDLQQILLCVEKFPSTYVRWLWGNHARVVIYDPDYMKVILGRSDPKVVRSYSFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDCPLEIYQDISLMTMETMMKCAFSYQGSVQLEENSKSYIKAVEDLTHLIYLRVRNGFHQNNTIYSLSSNGRSFYHACQIAHKHTERVIRMRKAQLQNEAELEKFRKKKRLDFLDILLFAQTEDGKSLSDEDVRAEMDTFMFEGHNTTASGISWIFYALATHPEHQQRCREEVKSILGNGTSVTLNHLDQMPYTTMCIKEALRLYPPIPGASRELSSPVTFPDGCSLPKGFLVTLSFYGLHHNPRLRPNAEVFDPSRFAPGAPRQTHAFLPFSAGTRNCIGKQFTMNELKVAVALTLLRFELLPDPTRVPILVSKIVLKSKNGIYLHTKKLK",
        "length": 508,
        "header": "tr|A0A087WS15-1|A0A087WS15_MOUSE Isoform 1 of Cytochrome P450, family 4, subfamily a, polypeptide 30b  OS=Mus musculus OX=10090 GN=Cyp4a30b PE=3 SV=1 CANONICAL=A0A087WS15-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A087WS15-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A087WS15/entry#A0A087WS15-1",
            "sequence": {
                "sequence": "MSIFELSHITNVFGIFGLLQVVSLLGLLLLLLKSAQYYLHRQWLIKSLQQFPPAPPPQWLFGNTLKDQDLQQILLCVEKFPSTYVRWLWGNHARVVIYDPDYMKVILGRSDPKVVRSYSFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDCPLEIYQDISLMTMETMMKCAFSYQGSVQLEENSKSYIKAVEDLTHLIYLRVRNGFHQNNTIYSLSSNGRSFYHACQIAHKHTERVIRMRKAQLQNEAELEKFRKKKRLDFLDILLFAQTEDGKSLSDEDVRAEMDTFMFEGHNTTASGISWIFYALATHPEHQQRCREEVKSILGNGTSVTLNHLDQMPYTTMCIKEALRLYPPIPGASRELSSPVTFPDGCSLPKGFLVTLSFYGLHHNPRLRPNAEVFDPSRFAPGAPRQTHAFLPFSAGTRNCIGKQFTMNELKVAVALTLLRFELLPDPTRVPILVSKIVLKSKNGIYLHTKKLK",
                "length": 508,
                "header": "tr|A0A087WS15-1|A0A087WS15_MOUSE Isoform 1 of Cytochrome P450, family 4, subfamily a, polypeptide 30b  OS=Mus musculus OX=10090 GN=Cyp4a30b PE=3 SV=1 CANONICAL=A0A087WS15-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 115328256,
                "end_pos": 115309801,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000119958.3",
                        "url": "https://www.ensembl.org/id/ENSMUST00000119958.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000140857.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000140857.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:435802",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:435802",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-211935",
            "name": "Fatty acids",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211935",
            "resource": "Reactome",
            "description": "Fatty acids"
        },
        {
            "id": "R-MMU-211958",
            "name": "Miscellaneous substrates",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211958",
            "resource": "Reactome",
            "description": "Miscellaneous substrates"
        },
        {
            "id": "R-MMU-211979",
            "name": "Eicosanoids",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211979",
            "resource": "Reactome",
            "description": "Eicosanoids"
        },
        {
            "id": "R-MMU-2142691",
            "name": "Synthesis of Leukotrienes (LT) and Eoxins (EX)",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2142691",
            "resource": "Reactome",
            "description": "Synthesis of Leukotrienes (LT) and Eoxins (EX)"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P20817-1",
            "protein_name": "Cytochrome P450 4A14",
            "gene_name": "Cyp4a14",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MGFSVFTPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHDLKDREFQQVLTWVEKFPGACLQWLSGSKTRVLLYDPDYVKVVLGRSDPKASGIYQFLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYGILKPYVKIMADSVNIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLTFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKMRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQIPYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRLKKLR",
                "length": 507
            },
            "evidence": [
                {
                    "id": "47560240",
                    "url": "http://www.informatics.jax.org/homology/47560240",
                    "database": "MGI"
                }
            ],
            "glygen_name": "Rat",
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q02928-1",
            "protein_name": "Cytochrome P450 4A11",
            "gene_name": "CYP4A11",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSVSVLSPSRLLGDVSGILQAASLLILLLLLIKAVQLYLHRQWLLKALQQFPCPPSHWLFGHIQELQQDQELQRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRRLPNPCEDKDQL",
                "length": 519
            },
            "evidence": [
                {
                    "id": "47560240",
                    "url": "http://www.informatics.jax.org/homology/47560240",
                    "database": "MGI"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5TCH4-1",
            "protein_name": "Cytochrome P450 4A22",
            "gene_name": "CYP4A22",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSVSVLSPSRRLGGVSGILQVTSLLILLLLLIKAAQLYLHRQWLLKALQQFPCPPSHWLFGHIQEFQHDQELQRIQERVKTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRLRRLPNPCEDKDQL",
                "length": 519
            },
            "evidence": [
                {
                    "id": "47560240",
                    "url": "http://www.informatics.jax.org/homology/47560240",
                    "database": "MGI"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 5,
                "go_terms": [
                    {
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