{ "uniprot_canonical_ac": "A0A087WR45-1", "uniprot_ac": "A0A087WR45", "uniprot_id": "A0A087WR45_MOUSE", "mass": { "chemical_mass": 106837.0, "monoisotopic_mass": 106837.0 }, "refseq": { "ac": "NP_001257575", "name": "proline-rich basic protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257575" }, "gene_names": [ { "name": "Prob1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A087WR45", "id": "A0A087WR45" }, { "name": "Gm1614", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257575", "id": "NP_001257575" }, { "name": "Gm1614", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A087WR45", "id": "A0A087WR45" }, { "name": "Prob1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257575", "id": "NP_001257575" } ], "protein_names": [ { "name": "Proline rich basic protein 1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A087WR45/entry#names_and_taxonomy", "id": "A0A087WR45" }, { "name": "proline-rich basic protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257575", "id": "NP_001257575" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A087WR45", "url": "https://www.uniprot.org/uniprot/A0A087WR45" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "gene": [ { "name": "Prob1", "url": "https://www.uniprot.org/uniprot/A0A087WR45", "locus": { "chromosome": "18", "start_pos": 35783404, "end_pos": 35788291, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000073600", "url": "https://www.ensembl.org/id/ENSMUSG00000073600" } ] } } ], "crossref": [ { "id": "A0A087WR45", "url": "https://alphafold.ebi.ac.uk/entry/A0A087WR45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSMUSG00000073600", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000073600", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "381148", "url": "https://www.ncbi.nlm.nih.gov/gene/381148", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:381148", "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:381148", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "2686460", "url": "http://www.informatics.jax.org/marker/MGI:2686460", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "AQFECVE", "url": "https://omabrowser.org/oma/group/AQFECVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A087WR45", "url": "https://www.orthodb.org/?gene=A0A087WR45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q3UKG2", "url": "https://www.orthodb.org/?gene=Q3UKG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33775:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33775:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15232", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001257575", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257575", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A087WR45", "url": "https://www.uniprot.org/uniprot/A0A087WR45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WR45-1", "url": "https://www.uniprot.org/uniprot/A0A087WR45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3UKG2", "url": "https://www.uniprot.org/uniprot/Q3UKG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3UKG2-1", "url": "https://www.uniprot.org/uniprot/Q3UKG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTALAPLALPGLSRRLPAPAGRQDSSGSSGSYHTAPGSPEPPDVGPDTEGRGTWLWVAPGRGAGAQPVLSVSAQNSRQQHGSGSGFPRGPGSGPLPPRPQLRMLPSGEMEVIFGAGPLFNRSDAEDLQEQQLMAPTFSSPQLPGPASPASVSSQPQVPDGGSRWATYLELPPREPSPAVSGQYECVEVALEERSAPVRPRTVPKRQIELRPRPRSPSQDSRAPRPRLLLRTGSLDESLSRLQAAAGIVQTALARKLGSAVPAPSNVTFKSTAKPESTTNSQETTDSTRVLLEEAKSRPPRAHDNSSSARVPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKPHQAYKQESKTQFPRETPDRTVPRARSPPFHSRGSRVVPSRVVRPRSPSPPQQAPNGSPHNPPQPSKIVWRRSSPAFPGGTSSAWENRNASVEEVVSRRTPSPPPLPQWTQGVARVGNPCPEAPLVWKVPNSRGGDAVGLSRDSSLPALLPREAPHPIETRTPSPGETWSPVVQGASTALHQEAMNGLTQELEPPTPSAPATPELTEALCLLSLENAGIAVRGGQRSPDVDTPEQPRSHLTSTLDDDVCPEAVGSGEAASERPRVTIPRPRDVRKMVKTTYAPSFPAGTPGSGLPAPPADTCGEDGDASKTHKLPALESPAPAHYTSIFLKDFLPVVPHPYESPEPSLHATPKDASQSSGVPRRRAENSTAKPFARSEIRLPGALAFGQRREKTPSVQRRGPGGENPDAEAQRLVRDPEGRTSPLGGARTSTQCSPLESTGTRPPRPGSPQACPNSSLRAAPELETPLVAPATAVQAPLLPDHPATAARAAAPFPRAASAPPTDRLPPASSLGRRPPGAAPAGKVLVDPESGRYYFVEAPRQPRLRLLFDPESGQYVEVLLPPSPSPSRQPRQPYAPLALGPGLYPPAYGPISGPSLSPLSPNLSALGSLQLPWAPEAGPLEGMYYMPLSGTPSPAPPMLFCAPPSSSGPIQSSKGSVFPL", "length": 1010, "header": "tr|A0A087WR45-1|A0A087WR45_MOUSE Isoform 1 of Proline rich basic protein 1 OS=Mus musculus OX=10090 GN=Prob1 PE=1 SV=1 CANONICAL=A0A087WR45-1" }, "isoforms": [ { "isoform_ac": "A0A087WR45-1", "url": "https://www.uniprot.org/uniprotkb/A0A087WR45/entry#A0A087WR45-1", "sequence": { "sequence": "MLTALAPLALPGLSRRLPAPAGRQDSSGSSGSYHTAPGSPEPPDVGPDTEGRGTWLWVAPGRGAGAQPVLSVSAQNSRQQHGSGSGFPRGPGSGPLPPRPQLRMLPSGEMEVIFGAGPLFNRSDAEDLQEQQLMAPTFSSPQLPGPASPASVSSQPQVPDGGSRWATYLELPPREPSPAVSGQYECVEVALEERSAPVRPRTVPKRQIELRPRPRSPSQDSRAPRPRLLLRTGSLDESLSRLQAAAGIVQTALARKLGSAVPAPSNVTFKSTAKPESTTNSQETTDSTRVLLEEAKSRPPRAHDNSSSARVPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKPHQAYKQESKTQFPRETPDRTVPRARSPPFHSRGSRVVPSRVVRPRSPSPPQQAPNGSPHNPPQPSKIVWRRSSPAFPGGTSSAWENRNASVEEVVSRRTPSPPPLPQWTQGVARVGNPCPEAPLVWKVPNSRGGDAVGLSRDSSLPALLPREAPHPIETRTPSPGETWSPVVQGASTALHQEAMNGLTQELEPPTPSAPATPELTEALCLLSLENAGIAVRGGQRSPDVDTPEQPRSHLTSTLDDDVCPEAVGSGEAASERPRVTIPRPRDVRKMVKTTYAPSFPAGTPGSGLPAPPADTCGEDGDASKTHKLPALESPAPAHYTSIFLKDFLPVVPHPYESPEPSLHATPKDASQSSGVPRRRAENSTAKPFARSEIRLPGALAFGQRREKTPSVQRRGPGGENPDAEAQRLVRDPEGRTSPLGGARTSTQCSPLESTGTRPPRPGSPQACPNSSLRAAPELETPLVAPATAVQAPLLPDHPATAARAAAPFPRAASAPPTDRLPPASSLGRRPPGAAPAGKVLVDPESGRYYFVEAPRQPRLRLLFDPESGQYVEVLLPPSPSPSRQPRQPYAPLALGPGLYPPAYGPISGPSLSPLSPNLSALGSLQLPWAPEAGPLEGMYYMPLSGTPSPAPPMLFCAPPSSSGPIQSSKGSVFPL", "length": 1010, "header": "tr|A0A087WR45-1|A0A087WR45_MOUSE Isoform 1 of Proline rich basic protein 1 OS=Mus musculus OX=10090 GN=Prob1 PE=1 SV=1 CANONICAL=A0A087WR45-1" }, "locus": { "chromosome": "18", "start_pos": 35788252, "end_pos": 35785223, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000190196.5", "url": "https://www.ensembl.org/id/ENSMUST00000190196.5" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140465.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140465.2" } ] } }, { "isoform_ac": "Q3UKG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A087WR45/entry#Q3UKG2-1", "sequence": { "sequence": "LAPLALPGLSRRLPAPAGRQDSSGSSGSYHTAPGSPEPPDVGPDTEGRGTWLWVAPGRGAGAQPVLSVSAQNSRQQHGSGSGFPRGPGSGPLPPRPQLRMLPSGEMEVIFGAGPLFNRSDAEDLQEQQLMAPTFSSPQLPGPASPASVSSQPQVPDGGSRWATYLELPPREPSPAVSGQYECVEVALEERSAPVRPRTVPKRQIELRPRPRSPSQDSRAPRPRLLLRTGSLDESLSRLQAAAGIVQTALARKLGSAVPAPSNVTFKSTAKPESTTNSQETTDSTRVLLEEAKSRPPRAHDNSSSARVPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKPHQAYKQESKTQFPRETPDRTVPRARSPPFHSRGSRVVPSRVVRPRSPSPPQQAPNGSPHNPPQPSKIVWRRSSPAFPGGTSSAWENRNASVEEVVSRRTPSPPPLPQWTQGVARVGNPCPEAPLVWKVPNSRGGDAVGLSRDSSLPALLPREAPHPIETRTPSPGETWSPVVQGASTALHQEAMNGLTQELEPPTPSAPATPELTEALCLLSLENAGIAVRGGQRSPDVDTPEQPRSHLTSTLDDDVCPEAVGSGEAASERPRVTIPRPRDVRKMVKTTYAPSFPAGTPGSGLPAPPADTCGEDGDASKTHKLPALESPAPAHYTSIFLKDFLPVVPHPYESPEPSLHATPKDASQSSGVPRRRAENSTAKPFARSEIRLPGALAFGQRREKTPSVQRRGPGGENPDAEAQRLVRDPEGRTSPLGGARTSTQCSPLESTGTRPPRPGSPQACPNSSLRAAPELETPLVAPATAVQAPLLPDHPATAARAAAPFPRAASAPPTDRLPPASSLGRRPPGAAPAGKVLVDPESGRYYFVEAPRQPRLRLLFDPESGQYVEVLLPPSPSPSRQPRQPYAPLALGPGLYPPAYGPISGPSLSPLSPNLSALGSLQLPWAPEAGPLEGMYYMPLSGTPSPAPPMLFCAPPSSSGPIQSSKGSVFPL", "length": 1006, "header": "tr|Q3UKG2-1|Q3UKG2_MOUSE Computationally mapped isoform of Proline rich basic protein 1 OS=Mus musculus OX=10090 GN=Prob1 PE=1 SV=1 CANONICAL=A0A087WR45-1" }, "locus": { "chromosome": "18", "start_pos": 35788240, "end_pos": 35785223, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000097619.2", "url": "https://www.ensembl.org/id/ENSMUST00000097619.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000095224.2", "url": "https://www.ensembl.org/id/ENSMUSP00000095224.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 545, "start_aa": "T", "end_pos": 545, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr545", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 551, "start_aa": "T", "end_pos": 551, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr551", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 981, "start_aa": "T", "end_pos": 981, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr981", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [ { "start_pos": 490, "end_pos": 490, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q3UKG2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UKG2" } ], "site_lbl": "Ser490" }, { "start_pos": 780, "end_pos": 780, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q3UKG2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UKG2" } ], "site_lbl": "Ser780" }, { "start_pos": 979, "end_pos": 979, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q3UKG2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UKG2" } ], "site_lbl": "Ser979" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UKG2", "url": "https://www.uniprot.org/uniprot/Q3UKG2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.", "journal": "Mol. Cell. Proteomics", "date": "2014", "authors": "Guo A, Gu H, Zhou J, Mulhern D, Wang Y, Lee KA, Yang V, Aguiar M, Kornhauser J, Jia X, Ren J, Beausoleil SA, Silva JC, Vemulapalli V, Bedford MT, Comb MJ", "evidence": [ { "database": "UniProtKB", "id": "Q3UKG2", "url": "https://www.uniprot.org/uniprot/Q3UKG2" } ], "reference": [ { "type": "PubMed", "id": "24129315", "url": "https://glygen.org/publication/PubMed/24129315" } ] } ], "pathway": [ { "id": "mmu:381148", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:381148", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y9A1-1", "protein_name": "Proline rich basic protein 1", "gene_name": "PROB1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIPRGKRDAGRPAEPPDGADGHGSPWEEDGRLSVLPRDDLPKSVSDSSISSYHSARCSETTDTFKDCLEFLEEDDAGRLTPPPPYVPPESPPSRGPGSGLREERGRQPQLSVTAKNSAAPGRGGRMGPLRGDRPPVVAFVERPCAAAPAAMLGEGRRARRGGGASDSDEADSEVRALTARSFRSLSGPPGARLDMCSSSSLSNSLSEDGGGGRRWAACGEPRGTELPGVPAKDLFECVDVELESGDAKKGYGKRRTVPKRQIQLKRKERKEAGFFPRGDSSAPQPLPPARKEPPGKGRAGSEDFRFNYKQFVKTASLDGDASKTRMASSLVKNVLAKKMQYEQLIKMEQQKVLRGSSTSSGPSSAGTDLLGDGMEGKSSSLSKSDLSASAEDVRLVDMRLGPFGAHRPAKGVVLSEATRENVCRLKKTFNELNERMRYQEVVQCQRLPAAEPSAERTPYWRARALFEGHSGDGKVPAVTPKFEKPQKPWPSLRQRAIRPSRPQLVPFEPKSLMPPDVPPRSVFTSQARDVRLGPQSRGEEKPPPAPREPPRPGASVGTPAEPGSKGKGLVPQPRDVRKLLKSNYSLSFGAARGPPAPGPSGESTGEPKPPSPLIIHCTSVRRSEPAPSIVPPAGGDVGMDGVREPAPARTEGTAASSSSHVAQGSPVQISKVQSVRREAPTTKSPQPSPDTCRQRSEIHVPSLVGTVEETHVESHLHVLVGPRSPPVAVEASPAQSSAVLRTEKTLLLPPPPLSPTEEDEERGHGVTMGESTGVDRHRSSGDNPGNVQDVKSAVRSTLKPPSSEPGSQLSSAGKHSPTDSTDPTAPFQAREAGEGPSVPPVPLSSRPLEQRETMEHVTTWPGASDPQLTAVQTDNSNYLTIPVKAPKPSPVPKVPPVPSLGTASFGTPLVPHPNSVSFGTPSVFGTPSVPSPATAPIGTPLVPRPTSMPFGTPLVPSPASASLGTSMVPNPASFETPVVSSLTSTSLGTPLVPSAANSSFGTPLFPYALSAPFGTPVVPSPATPSFGTASVPRLPNSTFGTSLVPNPSSTPFPTLSVPNPASSSFGVPLVPNPSYTPFASPSVPKQASSSFGTPLVPGPATMSFGTVPVSRPPNSTFGAPLVPNPSSTPFMTPSVPMPASSSYGTPMVNNPDPTSLGYPSISNVARSSFGSPLFPSPASAPLGTGVSPHPSGEAPWNKPLPEPPQPSDALTTAVPPAQPQRHVEDAPRRTEGSSPSSKSTPSPTRPFAPHASAHRKMLVDPDSGKCYYMEAPRQPQLKTLYDPETGQYMEVLIPPVPVASHAGFYQSPFNPMLYGTPYMAYGSFPGLPAPPPPTASSPAHPDLQGQPPTSENPGGFPGTFSPNPKGEGPPAAGGPDCGYLESPYYIPTGMRASPSPSQPPARASPASTEKGPLPPM", "length": 1416 }, "evidence": [ { "id": "A0A087WR45", "url": "https://omabrowser.org/oma/group/A0A087WR45/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7EW31-1", "protein_name": "Proline-rich basic protein 1", "gene_name": "PROB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFPL", "length": 1015 }, "evidence": [ { "id": "47564127", "url": "http://www.informatics.jax.org/homology/47564127", "database": "MGI" }, { "id": "A0A087WR45", "url": "https://omabrowser.org/oma/group/A0A087WR45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1M6Z4-1", "protein_name": "Proline-rich basic protein 1", "gene_name": "Prob1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTALAPLALPGLSRRLPASAGRQDSSGSSGSYHTAPGSPEPPDVGPDTEGQGTWLWVASGRGAGAQPVLSVSAQNSRQQHCSGSGFPRGPGSGPPLPQPQLRMLPSGEMEVIFGAGPLFSRSDAEDLEEQQLVAPTFSSPLLPGPASPVSVSSQPQVPDGGSRWATYLELPPREPSPAVSGQYECVEVALEERTAPVRPRTVPKRQIELRPRPRSPSQDSRAPRPRLLLRTGSLDESLSRLQAAAGIVQTALARKLGSAVPAPSNVTLKSTGKRESTTNSQETAASTHVVLEEAKSRPPRAHDHSASAKAPRPWPSLRERAIRRDKPPPGTEPLGPVSSSIFLQSEEKIHQAHKQEPKTQFPRETPDRTVPRARSPPSRGSRVVPSRVVRPRSPSPPLQAPNGAVRGPRCPSPQNLPQPHKIVWRTSSPAFPGASSAWEDRNASVEEVVSRRTPSPPPLSQWTQGVARVGNPCPEAPLLWKVPNSRGGDAAGLSRDPSLPALLPRESPHPIETRSPSPGETWSPIAQASSTALRQEALNGLTQKLESPTPSAPGTPELPEAQCLLSLENANIAFRDGQPSPDVDTTEQPRSHLTSILDDDVCPETLGSGEATSGRPRVTIPRPRDVRKMVKTTYAPSFPAGTPGSGLPAPPADTCGEEGDVSKTQKLPALESPAPAHYTSIFLKDFLPVVPHPYETPEPSLPATPKDASQSSGVPRRRAENSTAKPFARSEIRLPGALAFGQRREKTPSVQRPGPGGENPDAEAQSLVPDREGPTSPLGGARTSTQRSPLESTGTRPPRPGSPQAGPNSSLRAAPELETPLVSPATAVQAPLLPDPPATAARTAAPFPRAASAPPTDRLHPASSLGMRRPPGAVPAGKVLVDPESGRYYFVEAPRQPRLRLLFDPESGQYVEVLLPPSPSPSRPPRQPYAPLALGPGLYPPVYGPISGPSLSPLSHNLPALGGLQLPWAPEAGSLEGMYYMPLSGTPSPAPPPLAFCGPPPSSGPIQSSKGSVFPL", "length": 1017 }, "evidence": [ { "id": "A0A087WR45", "url": "https://omabrowser.org/oma/group/A0A087WR45/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MVC9-1", "protein_name": "Proline rich basic protein 1", "gene_name": "PROB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLTAFAQPALPGFPGRLPAAPARRQDSSGSSGSYHTAPGSPEPPDVGPDAEGRANWPRVAPALGAGVQPRLSVSAQNSRQQLLPGSGFPRGPASGLRPPQPQLRMLPSGEMEVIFGAGPLFSRSDAEDREVQQLTTRAFRSLSPPGSTSPIPDEPQPQGPDGGSRWATYLELRPRAASPATPSQFECVEVALEEHTAPARPRTVPKRQIELRPRPRSPPREANAPRPRLLLRTGSLDESLSRLQAAADLVQTALARKLSPAPPAPSNATFGPTVPPEPATPETLRSTRVALEEAKSLPPRVNYSSAPARAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLKSGEKPEEVHQKEPKARFPRDTPAQTVLRAQGPPFQSRPPWEVSSKAVRRRSPSPPWEAPNGTVRGPHCTSPQNLSPWNRTIRKVSSPSIPEASSTWDNQDAAVTETVSRKSPSPPTLSQWNRGVARAKSPSPEAPSSWEVPDPAVGDAVEGSRSPSPPTLPSWETPDRSVGTWSPSPQETWNSTVQSSSVVSTPVAINGAAQEELVPPTPSAPGTPKLTEIQSPSTREIPDLTSRGNQLSPEVAAPQLPLSRTVDVDVLPEAVGSGKAASGRPRVAIPRPRDVRKMVKTTYAPSFAASTPDSGLPAPPAEPRGEEGSASKTQELQALGPPAPSHYTSIFLKDFLPVVSHPYEPPEPTPDTVPRDVTQSNGVLRRRAENSTAKPFARTEIRLPGALALGRRPERTRGVAVHGPGGKNRDAEAQRLVPDNKGRTSPLGGARTSPQQSPIGPAETQPPGPPRPSSPQAHPSSSSGMESELETPPKALEPAVAVQPPLLREPQASTRRTARAQPRAASAPPLDRSADGSSQGTRRPPGAANPGKVLVDPESGRYYFVEAPRQPRLRLLFDPESGQYVEVLLPPSPSVPPRRVYTPLALGPGLYPPAYGPLPGLSLPPSPGPPAFSGPQLPWASEAGPLDGMYYLPASGGPASLGVTAPLDLDWKQRTMSQNNLDIFLWPEMLMPRRALGHSWAPHFIVMCNKPNGPNGWKNWREVSDFLLRPLNTPYNAVHAWVWLGGEYHMCLS", "length": 1085 }, "evidence": [ { "id": "A0A087WR45", "url": "https://omabrowser.org/oma/group/A0A087WR45/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RGH4-1", "protein_name": "Proline-rich basic protein 1", "gene_name": "PROB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTTFAPPALLRLPGRLPAGPARRQDSSGSSGSYHTAPGSPEPPDVGPDAEGWANWPGVAPALGAGVQPRLSVSAQNSRQQLGPGSGFPQGPGSGPQPPRPQLRMLPSGEMEVIFGAGPLFSRSDAEDSEVQQLTSPALGSLPPPESVSPGAAEPQPQGPDGGSRWATYLELRPHGPSPATPAQFECVEVALEERAAPARPRTVPKRQIELRPRPRSPPREAGAPRPRLLLRTGSLDESLGRLQAAADLVQTALARKLNPATPTPSSATFGPTIPPEPATPETPRSTRVALEEARSRPPRVQYSPAPARAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSGEKTQEAHNQDPKPRETPDRTGLRAQNPPFESRAPWEISSEAVRPRSPSPLWQGPNGTLRGPHCPSPPKPCPWNRAVQKVSRSSLPEASSTGGNRDAAVTETVSRKSPSPPTLSQWNQGIAGARSPSPEAPSSWEGPRPAVSERVEETRSPSPPVLSSWEAPDRPLRTWSPSPQETWDPSGQSSSVVSTREAVNGLAQEELVPPTPSAPGTPELAEEQSPSTREMRDLAFQGSQLSPEVASPQPPLSRLVGTPDASAHPEALGPGDATSGRPRVTIPRPRDVRKMVKTTYAPSFAAGTSGSGLSAPPADPGEEEGDASKTREIQALGPPAPAHYTSVFLKDFLPVVSHPYEPPEPPPDTAPRDVTQPNGVVRRRAENSTAKPFARTEIRLPGALAVARRPEGTRGVLVHCPGGKDRDAEPQRLVPDDRGRTSPLGGARTPPPRSPAGSAGPQAPRPPRRRSPQAPPSPSLGGARRRETPAPAPEPALAVQAPLPRQPQASAPRAAPPQPRAASAPPMDRAPEGPSQGARRLPGAAHPGKVLVDPESGRYYFVEAPRQPRLRLLFDPESGQYVEVLLPPSPSVPSRRIYTPVALGPGLYPPAYGPVPGLSLPPSPGPPAFSGTQLPWASEAGALDGMYYLPVSGTPSPAPPLLLCAAPPSGLGPVQPSKGSLFPV", "length": 1019 }, "evidence": [ { "id": "A0A087WR45", "url": "https://omabrowser.org/oma/group/A0A087WR45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR45", "url": "https://www.uniprot.org/uniprot/A0A087WR45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 717, "end_pos": 719, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" }, { "start_pos": 952, "end_pos": 954, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A087WR45-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1010, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A087WR45-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 545, 551, 981 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 490, 780, 979 ], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 717, "end_pos": 719 }, { "start_pos": 804, "end_pos": 806 }, { "start_pos": 952, "end_pos": 954 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 3 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 3 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "mining_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }