{ "uniprot_canonical_ac": "A0A087WR13-1", "uniprot_ac": "A0A087WR13", "uniprot_id": "A0A087WR13_MOUSE", "mass": { "chemical_mass": 462050.0, "monoisotopic_mass": 462050.0 }, "refseq": { "ac": "NP_001297264", "name": "dynein, axonemal, heavy chain 7C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297264" }, "gene_names": [ { "name": "Dnah7c", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A087WR13", "id": "A0A087WR13" }, { "name": "Dnah7c", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297264", "id": "NP_001297264" }, { "name": "Dnahc7c", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297264", "id": "NP_001297264" } ], "protein_names": [ { "name": "Dynein, axonemal, heavy chain 7C", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A087WR13/entry#names_and_taxonomy", "id": "A0A087WR13" }, { "name": "dynein, axonemal, heavy chain 7C", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297264", "id": "NP_001297264" } ], "function": [], "disease": [ { "disease_id": "DOID:9562", "recommended_name": { "id": "DOID:9562", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube." }, "synonyms": [ { "id": "DOID:9562", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9562", "name": "ciliary motility disorder", "description": "" }, { "id": "DOID:9562", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9562", "name": "immotile ciliary syndrome", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "primary ciliary dyskinesia 1", "description": "Any primary ciliary dyskinesia in which the cause of the disease is a mutation in the DNAI1 gene." }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "CILD1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "DNAI1 primary ciliary dyskinesia", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "ciliary dyskinesia, primary, type 1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "primary ciliary dyskinesia 1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "primary ciliary dyskinesia 1 with or without situs inversus", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "primary ciliary dyskinesia caused by mutation in DNAI1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "primary ciliary dyskinesia type 1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "Kartagener syndrome", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "PCD", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "Polynesian bronchiectasis", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "Siewert syndrome", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "ciliary dyskinesia, primary, 1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "ciliary dyskinesia, primary, 1, with or without situs inversus", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "dextrocardia, bronchiectasis, and sinusitis", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "immotile cilia syndrome", "description": "" }, { "id": "MIM:244400", "resource": "MIM", "url": "https://www.omim.org/entry/244400", "name": "Kartagener syndrome", "description": "Kartagener syndrome" } ], "evidence": [ { "id": "9562", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388467858", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388467858" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 1743, "end_pos": 1743, "sequence_org": "T", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (TVS->NVS).", "chr_id": "1", "chr_pos": "46677906", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T1743", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs3388468443", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388468443" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 3261, "end_pos": 3261, "sequence_org": "H", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (HFT->NFT).", "chr_id": "1", "chr_pos": "46787729", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H3261", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "gene": [ { "name": "Dnah7c", "url": "https://www.uniprot.org/uniprot/A0A087WR13", "locus": { "chromosome": "1", "start_pos": 46846636, "end_pos": 46464752, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000101337", "url": "https://www.ensembl.org/id/ENSMUSG00000101337" } ] } } ], "crossref": [ { "id": "ENSMUSG00000101337", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000101337", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100101919", "url": "https://www.ncbi.nlm.nih.gov/gene/100101919", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:100101919", "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:100101919", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "3639762", "url": "http://www.informatics.jax.org/marker/MGI:3639762", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "MMQPRSH", "url": "https://omabrowser.org/oma/group/MMQPRSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A087WR13", "url": "https://www.orthodb.org/?gene=A0A087WR13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45703", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45703", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45703:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45703:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46961", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46961", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46961:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46961:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03028", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF08393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08393", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12774", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12775", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12777", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12780", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12781", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF17852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17852", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF17857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17857", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF18198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18198", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF18199", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18199", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001297264", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297264", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WR13-1", "url": "https://www.uniprot.org/uniprot/A0A087WR13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QYG9", "url": "https://www.uniprot.org/uniprot/F6QYG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QYG9-1", "url": "https://www.uniprot.org/uniprot/F6QYG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSKKDKLSTKGKSKMPARFLPQLPMDKLSSKEKAKLPTTVLPQLTLTGVKHQWQQTAPSFHLNIKQENPILEPYTVKNEQSFAEYMEHYRRKGKLLDQIDDDRSAPSTSRSKVKSPHKERENLRSTLVKVIMQQDGGLESDVIDESGIPKVATSPREKDILRYYYYIRHGIDSDHVAPLEDSWLEHVLQLVPQHLKVMTNSIMVLSDEIREDYLLSVKKSIVDFVLKDPREKDDDGKITELPPHRAEIEVLPKPWRRSFLSACSYIRDHLNAMNPMMLAVLDLWHSTFKKLRLVDIEEFHKRQDALELSEFQNIVIKHMESAKETLLKTWFPEVQNIYYKGNKKKQLPTGKSSAKLDSFFNCAATLMTLQLQDLILVSMQDFTDLIAQPPESTRAFEHPGFIMRLVLDKDNISFEPEFNDYIDILVNIYEIMIKAVSFVPRVETKLYSQWESKSKPTTLKPIILNEIIDGHKEKIREVILRESVAPTEHLKMYDKYQFLITGKAERDIDEFLFQSQNYERLIEEIRKYQKLEEEIQYTSRKAVRLGMFEMHCEELIKSLVKRADIICGKLIAKMFRNHQKESTMLCDEFEKIAEKALSTPLNTAELMEMKADIQKVETTDMLELRQRLVDSKNCLAFLIECVNFSPADIRLNNSVFQWYGRMGEIFDEHRKIIKDKTEQYQEALKFRCERFVEELESYAKQVEEFHTFGDLMDMQRYLQKAQVLNSKLDAAADKIDQFNAEEEAYGWVPSVYPQRKKIQDALNPYLRLYETAVEFSAKHKWWTEGPYHKVNPDQVETDVGNYWRGLYKLEKVFHDSPNALAMTKKVQSMVEEFKQYIPLIQVICNPGLHPRHWEAMSTIVGYPLKPSDDSTVLSFIDMNLEPFLDRFEGISEAASKEYSLEKAMDKMMTEWNSMEFVIHPYRESGTYILSSVDDIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFKAVDKTWRDMMKTVVQDKQVLAVVTIERMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELVDTISTAKARGQVEKWLVELERTMIKSIHKVIRDAIAAYTKYSRISWVRDWPGQTVLCVSQTFWTVEVQTAIPKGHQALEDYLAKCNQQIDDIVTLVRGKLSKQNRVTLGALVVLDVHARDVLASLADKKISDDSDFQWLSQLRYYWQENNLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGTDLLVFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSIKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIRDNCHTMNLQMTDFFSEKILQIYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDLVSHEWSDGVLAVSFRAFAASSTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMVSWINTLPQSVSIIQKEFIEGLFDRMVPLSVEFIRRHTKELSPTSDTNLVHSLMNLIDCFMDDFADENKQKERNDQESFSLLEGIFLFSLIWSVGATCTDDDRMKFDKILRELMEGPISDQTRNKFTLLSSTEQTSSKAFIVPFPEKGTIYDYQFILEDLGRWDKWIKKLADTPPIPKDVQFNEIIVPTLDTVRYSALMHLLTTHQKPSIFVGPTGTGKSVYIINFLLNQLNKDIYKPLIVNFSAQTTAAQTQNIIMSKLDKRRKGVFGPPLGKRMIVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSVIKLVDIQIMCAMGPPGGGRNPITPRYMRHFNIVTINEFSDKSMFTIFSRILAWHLRTCYKFPDDFLDMTTQIVNGTMALYKDAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETAENKEAIKRLWVHEVLRVYYDRLVDNADRGWLINYIQGILKNYMQEDFHDLFKNLDFNHDGTVEEDDLRSLMFCDFHDPKREDFGYREVENVDALRMIVEGHLDEYNNMSKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSLFQVEISKGYGSHEWHEDLKVILRKCAENDMQGVFLFTDTQIKRESFLEDVNNLLNAGEVPNLFALDEKQEICEKMRQLDRQRDKTKQTDGSPIALFNMFIDRCRNQLHVVLAMSPIGDAFRIRLRKFPALVNCCTIDWFQSWPEDALEAVASRFLEDIEMSEETQEGCIDMCKRFHTSTINLSTSFHNELQRYNYVTPTSYLELISTFKLLLEKKRNEVMKMKRRYEVGLDKLDSASSQVATMQSELEALHPQLKVASREVDEMMIIIERESMEVAKTEKIVKADETVANDQAMAAKAIKDECDADLAEALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAVCILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDIRFLQSLHEYDKDNIPPAYMNIIRKSYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGKLRIAMEGLRKKQAALYEVQDKLAKLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSNSALELGHLYINLTGDILISSGVVAYLGAFTSNYRQNQTKEWSQSCKERDIPCSDDYSLMGTLGEAVTIRAWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQGQANKWIKNMEKTNSLQLIKLSDPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVARERPDLEEEKQALIVQGADNKRQLKEIEDKILEVLSLSEGNILEDETAIKILSSSKSLANEISQKQEVAEETEKKIDNTRMGYRIIAIHSSILFFSIADLANIEPMYQYSLTWFINLFILSIENSEKSDILSKRLQILRDHFTYSLYVNICRSLFEKDKLLFSFCLTVNLLIHDNLINKTEWRFLLTGGIGLDNPYTNPCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSMEPHHEMFPEDWENKANDFQRMLIIRCLRPDKVIPMLQEFIIKKLGRPFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMNALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKDGTWVVLQNCHLATSWMPTLEKVCEELNPESTHPDFRIWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFDSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLDQYEELPYDALRYMTGECNYGGRVTDDWDRRTLRSILNKFFCTELVENPQYKFDSSGIYFIPPSGDHKSYIDYTKTLPLIPAPEVFGMNANADITKDQSETQLLFDNILLTQSQSSGSGTKSSDEVVNEVAGDILSKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLITIRESCINIQKAIKGLVVMSTELEEVVSSILNVKIPAMWMGKSYPSLKPLGSYVNDFLERLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKFTIPIDLLAFDYEVMDDKEYKNAPEDGVYIHGLFLDGASWDRKTKKLAESHPKVLYDTVPVMWLKPCKKSDISKRPSYVAPLYKTSERRGTLSTTGHSTNFVIAMILPSDQPKEHWIGRGVALLCQLNS", "length": 4024, "header": "tr|A0A087WR13-1|A0A087WR13_MOUSE Isoform 1 of Dynein, axonemal, heavy chain 7C OS=Mus musculus OX=10090 GN=Dnah7c PE=1 SV=1 CANONICAL=A0A087WR13-1" }, "isoforms": [ { "isoform_ac": "A0A087WR13-1", "url": "https://www.uniprot.org/uniprotkb/A0A087WR13/entry#A0A087WR13-1", "sequence": { "sequence": "MSSKKDKLSTKGKSKMPARFLPQLPMDKLSSKEKAKLPTTVLPQLTLTGVKHQWQQTAPSFHLNIKQENPILEPYTVKNEQSFAEYMEHYRRKGKLLDQIDDDRSAPSTSRSKVKSPHKERENLRSTLVKVIMQQDGGLESDVIDESGIPKVATSPREKDILRYYYYIRHGIDSDHVAPLEDSWLEHVLQLVPQHLKVMTNSIMVLSDEIREDYLLSVKKSIVDFVLKDPREKDDDGKITELPPHRAEIEVLPKPWRRSFLSACSYIRDHLNAMNPMMLAVLDLWHSTFKKLRLVDIEEFHKRQDALELSEFQNIVIKHMESAKETLLKTWFPEVQNIYYKGNKKKQLPTGKSSAKLDSFFNCAATLMTLQLQDLILVSMQDFTDLIAQPPESTRAFEHPGFIMRLVLDKDNISFEPEFNDYIDILVNIYEIMIKAVSFVPRVETKLYSQWESKSKPTTLKPIILNEIIDGHKEKIREVILRESVAPTEHLKMYDKYQFLITGKAERDIDEFLFQSQNYERLIEEIRKYQKLEEEIQYTSRKAVRLGMFEMHCEELIKSLVKRADIICGKLIAKMFRNHQKESTMLCDEFEKIAEKALSTPLNTAELMEMKADIQKVETTDMLELRQRLVDSKNCLAFLIECVNFSPADIRLNNSVFQWYGRMGEIFDEHRKIIKDKTEQYQEALKFRCERFVEELESYAKQVEEFHTFGDLMDMQRYLQKAQVLNSKLDAAADKIDQFNAEEEAYGWVPSVYPQRKKIQDALNPYLRLYETAVEFSAKHKWWTEGPYHKVNPDQVETDVGNYWRGLYKLEKVFHDSPNALAMTKKVQSMVEEFKQYIPLIQVICNPGLHPRHWEAMSTIVGYPLKPSDDSTVLSFIDMNLEPFLDRFEGISEAASKEYSLEKAMDKMMTEWNSMEFVIHPYRESGTYILSSVDDIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFKAVDKTWRDMMKTVVQDKQVLAVVTIERMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELVDTISTAKARGQVEKWLVELERTMIKSIHKVIRDAIAAYTKYSRISWVRDWPGQTVLCVSQTFWTVEVQTAIPKGHQALEDYLAKCNQQIDDIVTLVRGKLSKQNRVTLGALVVLDVHARDVLASLADKKISDDSDFQWLSQLRYYWQENNLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGTDLLVFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSIKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIRDNCHTMNLQMTDFFSEKILQIYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDLVSHEWSDGVLAVSFRAFAASSTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMVSWINTLPQSVSIIQKEFIEGLFDRMVPLSVEFIRRHTKELSPTSDTNLVHSLMNLIDCFMDDFADENKQKERNDQESFSLLEGIFLFSLIWSVGATCTDDDRMKFDKILRELMEGPISDQTRNKFTLLSSTEQTSSKAFIVPFPEKGTIYDYQFILEDLGRWDKWIKKLADTPPIPKDVQFNEIIVPTLDTVRYSALMHLLTTHQKPSIFVGPTGTGKSVYIINFLLNQLNKDIYKPLIVNFSAQTTAAQTQNIIMSKLDKRRKGVFGPPLGKRMIVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSVIKLVDIQIMCAMGPPGGGRNPITPRYMRHFNIVTINEFSDKSMFTIFSRILAWHLRTCYKFPDDFLDMTTQIVNGTMALYKDAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETAENKEAIKRLWVHEVLRVYYDRLVDNADRGWLINYIQGILKNYMQEDFHDLFKNLDFNHDGTVEEDDLRSLMFCDFHDPKREDFGYREVENVDALRMIVEGHLDEYNNMSKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSLFQVEISKGYGSHEWHEDLKVILRKCAENDMQGVFLFTDTQIKRESFLEDVNNLLNAGEVPNLFALDEKQEICEKMRQLDRQRDKTKQTDGSPIALFNMFIDRCRNQLHVVLAMSPIGDAFRIRLRKFPALVNCCTIDWFQSWPEDALEAVASRFLEDIEMSEETQEGCIDMCKRFHTSTINLSTSFHNELQRYNYVTPTSYLELISTFKLLLEKKRNEVMKMKRRYEVGLDKLDSASSQVATMQSELEALHPQLKVASREVDEMMIIIERESMEVAKTEKIVKADETVANDQAMAAKAIKDECDADLAEALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAVCILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDIRFLQSLHEYDKDNIPPAYMNIIRKSYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGKLRIAMEGLRKKQAALYEVQDKLAKLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSNSALELGHLYINLTGDILISSGVVAYLGAFTSNYRQNQTKEWSQSCKERDIPCSDDYSLMGTLGEAVTIRAWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQGQANKWIKNMEKTNSLQLIKLSDPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVARERPDLEEEKQALIVQGADNKRQLKEIEDKILEVLSLSEGNILEDETAIKILSSSKSLANEISQKQEVAEETEKKIDNTRMGYRIIAIHSSILFFSIADLANIEPMYQYSLTWFINLFILSIENSEKSDILSKRLQILRDHFTYSLYVNICRSLFEKDKLLFSFCLTVNLLIHDNLINKTEWRFLLTGGIGLDNPYTNPCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSMEPHHEMFPEDWENKANDFQRMLIIRCLRPDKVIPMLQEFIIKKLGRPFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMNALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKDGTWVVLQNCHLATSWMPTLEKVCEELNPESTHPDFRIWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFDSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLDQYEELPYDALRYMTGECNYGGRVTDDWDRRTLRSILNKFFCTELVENPQYKFDSSGIYFIPPSGDHKSYIDYTKTLPLIPAPEVFGMNANADITKDQSETQLLFDNILLTQSQSSGSGTKSSDEVVNEVAGDILSKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLITIRESCINIQKAIKGLVVMSTELEEVVSSILNVKIPAMWMGKSYPSLKPLGSYVNDFLERLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKFTIPIDLLAFDYEVMDDKEYKNAPEDGVYIHGLFLDGASWDRKTKKLAESHPKVLYDTVPVMWLKPCKKSDISKRPSYVAPLYKTSERRGTLSTTGHSTNFVIAMILPSDQPKEHWIGRGVALLCQLNS", "length": 4024, "header": "tr|A0A087WR13-1|A0A087WR13_MOUSE Isoform 1 of Dynein, axonemal, heavy chain 7C OS=Mus musculus OX=10090 GN=Dnah7c PE=1 SV=1 CANONICAL=A0A087WR13-1" }, "locus": { "chromosome": "1", "start_pos": 46846522, "end_pos": 46464773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000189749.7", "url": "https://www.ensembl.org/id/ENSMUST00000189749.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140430.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140430.2" } ] } }, { "isoform_ac": "F6QYG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A087WR13/entry#F6QYG9-1", "sequence": { "sequence": "LVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGTDLLVFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSIKIVATYRLCSEQLSSQHHYDYGMRA", "length": 204, "header": "tr|F6QYG9-1|A0A087WR13_MOUSE Computationally mapped isoform of Dynein, axonemal, heavy chain 7C OS=Mus musculus OX=10090 GN=Dnah7c PE=1 SV=1 CANONICAL=A0A087WR13-1" }, "locus": { "chromosome": "1", "start_pos": 46665271, "end_pos": 46648121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000178395.2", "url": "https://www.ensembl.org/id/ENSMUST00000178395.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000136771.2", "url": "https://www.ensembl.org/id/ENSMUSP00000136771.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 1978, "start_aa": "T", "end_pos": 1978, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr1978", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 2170, "start_aa": "T", "end_pos": 2170, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr2170", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "mining_tool": "", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 2559, "start_aa": "T", "end_pos": 2559, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr2559", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "mmu:100101919", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:100101919", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q0T8-1", "protein_name": "Dynein, axonemal, heavy chain 7A", "gene_name": "Dnah7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSKKDKLSTKGKSKTPVRFLPQLPMDKLSSKEKVKLPTTVLPQLSLTGVKPQWQQTAPSFHLNIKQENPVLEPYTVKNEQSFAEYMEHCQKKGKLLDQIDDDRSAPSTSRSKIKSPQKERENLRSTLAKVIMQKDGGLESDVIDESGIPKETTSATEKDISRYYYYIRQGLDTDHVAPMEDSWLEHVLQLVPEHLKVLTNSIKVLSDEIREDYLLSVKKSIVDFVLKDPREKDDDGKITELPPHRAEMEVLPKPWRRSFLSACSYIRDHLNAMNPMMLAVLDLWHSTFKKLRLVDIEEFHSCQDALELSEFQNIVIKHMESAKETLLKTWFPEVQNIFNQGNKKKQLPTGKSTAKLDSFFNCAATLMTLQLQDLILVSMQDFTDLIAQPLESIRVFEHPGFIMRLVLDKEAIKFEPEFNEYIDSLINIYEIMIKAVSFVPRVETKLYSQWESKSKPTTLKPIILNEIIDTHKEKIREVILRESVAPTEHLKMYDKYQFLITGKAERDIDELLFQNQNYERLIEEIRKYQKLGEEIQYTSQKTVCLGMFEMHCEELIRSLVKRADVICGKLIAKMFRDHQEVNTMLCDEFEKIAEKALSTPLNTAELMEMKAHVQKLETTDMLELGQRLVDSKICLAFLIECVNFSPADIRLNKSVFQWYGRMGEIFDEHRKIIKEKTELYQEFLKFRCERFVEELESYAKQVEEFHAFGDLLDVQRYLQKAQVLNGKLDAAADKIDQFNAEEEAFGWVPSAYPQRKKIQDALNPYLHLYETAVEFSTKHRGWTEGPYHKVNPDQVEADVGNYWRGLYKLEKVFHDSPNALAMTKKVHSMVEEFKQYIPLIQVFCNPGLRPRHWEAMSTIVGYPLQPSDDSTVFSFIDMNLEPFLDRFGSISEAASKEYSLEKAMDKMMTEWDSMEFVILPYRESGTYILSSVDDIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSRDIMSQMPEEGRRFTAVDKTWRDVMKTVVQDKQVLAVVTIERMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELVDTISTAKARGQVEKWLVELERTMIKSIHKVIRDAIVAYTKTSRISWVRDWPGQTVLCVSQTFWTVEVQIAIPEGHRALEGYLAKCNHQIDDIVTLVRGKLSKQNRVTLGALVVLDVHARDVLASLVDKKISDDSDFQWLSQLRYYWQENNLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGTDLLVFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSIKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIRDNCHSMNLQMTDFFSEKILQIYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDLVSHEWSDGVLAVSFRAFAASSTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMVSWINTLPQSVSIIQKEFIEGLFDRMVPLSVEFIRRHTKELSPTSDTNLVRSLMNLIDCFMDDFADENKQKERNDRESFSLLEGIFLFSLIWSVGATCTDDDRLKFDKILRELLEGPISNLTRNKFKLLSGTEQTSSKVFIVPFPEKGTIYDYQFIPEGLGRWDKWIKDLADTPPIPKDVQFNEIIVPTLDTIRYSALMNLLTTHQKPSIFVGPTGTGKSVYIINFLLNQLNKDIYKPLIVNFSAQTTAAQTQNIIMSKLDKRRKGVFGPPLGKRMIVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSVIKLVDIQIMCAMGPPGGGRNPITPRYMRHFNIVTINEFSNKSMFTIFSRILAWHLRTCYKFPDDFLDLTTQIVNGTMALYKDAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETAENKEAIKRLWVHEVLRVYYDRLVDNADRSWLINYIQEILKNYMQEDFHDLFKNLDFNHDGTVEEDDLRSLMFCDFHDPKREDFGYREIANVDALRMIVEGHLDEYNNMSKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSLFQVEISKGYGSHEWHEDLKVILRKCAESDMQGVFLFTDTQIKRESFLEDVNNLLNAGEVPNLFALDEKQEICEKMRQIDRQRDKSKQTDGSPIALFNMFIDCCRNQLHVVLAMSPIGDAFRIRLRKFPALVNCCTIDWFQSWPEDALEAVASRFLEDIEMSEEIREGCIDMCKRFHTSTINLSTSFHNELQRYNYVTPTSYLELISTFKLLLEKKRNEVMKMKRRYEVGLDKLDSASSQVATMQSELEALHPQLKVASREVDEMMIIIERESMEVAKTEKIVKADETVANDQAMAAKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAVCILKGIKADKIPDPTGSGKKTEDFWGPAKRLLGDIRFLQSLHEYDKDNIPPAYMNIIRKSYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGKLKVAMEGLRKKQAALHEVQDKLAKLQDTLELNKQKKADLEHQVDLCSKKLERAEQLIGGLGGEKTRWSNSALELGHLYINLTGDILISSGVVAYLGAFTSNYRQNQTKQWSQSCKERDIPCSDDYSLMGTLGEAVTIRAWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQGQANKWIKNMEKTNSLQLIKLSDPSYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYSPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVARERPDLEEEKQALILQGADNKRQLKEIEDKILEVLSLSEGNILEDETAIKILSSSKSLANEISQKQEVAEETEKKIDITRMGYRPIAIHSSILFFSIADLANIEPMYQYSLTWFINLFILSIENSEKSDILSKRLQILRDHFTYSLYVNICRSLFEKDKLLFSFCLTVNLLIHDNAINKTEWRFLLTGGIGLDNPYTNPCTWLPQKSWDEICRLDDLPAFKTIREEFMRLKDGWKKVYDSMEPHHEMFPEDWGNKANDFQRMLIIRCLRPDKVIPMLQEFIIKKLGRSFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMNALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKDGTWVVLQNCHLATSWMPTLEKVCEELSAESTHPDFRIWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLDQYEELPYDALRYMTGECNYGGRVTDDWDRRTLRSILNKFFCTELVENPQYKFDSSGIYFVPPSGDHKSYIDYTKTLPLIPAPEVFGMNANADITKDQSETQLLFDNILLTQSHSSGSGTKSSDEVVNEVAGDILGKLPNNFDVEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLITIRESCINIQKAVKGLVVMSTELEEVVSSILNVKIPAMWMGKSYPSLKPLGSYVNDFLERLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKFTIPIDLLGFDYEVMDDKEYKKAPEDGVYIHGLFLDGASWDRKTKKLAESHPKVLYDTVPVMWLKPCKKSDIPRRPSYVAPLYKTSERRGTLSTTGHSTNFVIAMILPSVHPKEHWIGRGVALLCQLNS", "length": 4024 }, "evidence": [ { "id": "A0A087WR13", "url": "https://omabrowser.org/oma/group/A0A087WR13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WXX0-1", "protein_name": "Dynein axonemal heavy chain 7", "gene_name": "DNAH7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSEQDKSASKEKSKKPVRFLPQLSMEKLASKEKFKAPARALPQLSMVSTKPHWQQAAPSFHLSVKQDDESPEPFSVKNEQSHAEYMERFGKKGKLPHQVDDSYVGPSTSKSKGKSPHKERENFRSTLVNVIMQQDADLDSAVPDGSTIPKPTASAIEKDILRYYYYIHHGIDTDHVAPMEDSWLEHVLDLVPQHLKVFTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDKKTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDIKEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKLESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIKALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQLNS", "length": 4024 }, "evidence": [ { "id": "47567702", "url": "http://www.informatics.jax.org/homology/47567702", "database": "MGI" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "inner dynein arm", "id": "GO:0036156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036156", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A087WR13", "url": "https://www.uniprot.org/uniprot/A0A087WR13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1353, "end_pos": 1355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2005, "end_pos": 2007, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2154, "end_pos": 2156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2305, "end_pos": 2307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2543, "end_pos": 2545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2785, "end_pos": 2787, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2903, "end_pos": 2905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2928, "end_pos": 2930, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3298, "end_pos": 3300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3607, "end_pos": 3609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1978, 2170, 2559 ], "snv_sites": [ 1743, 3261 ], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1353, "end_pos": 1355 }, { "start_pos": 2005, "end_pos": 2007 }, { "start_pos": 2154, "end_pos": 2156 }, { "start_pos": 2305, "end_pos": 2307 }, { "start_pos": 2543, "end_pos": 2545 }, { "start_pos": 2785, "end_pos": 2787 }, { "start_pos": 2903, "end_pos": 2905 }, { "start_pos": 2928, "end_pos": 2930 }, { "start_pos": 3298, "end_pos": 3300 }, { "start_pos": 3607, "end_pos": 3609 }, { "start_pos": 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