{
    "title": "The quaking I-5 protein (QKI-5) has a novel nuclear localization signal and shuttles between the nucleus and the cytoplasm.",
    "journal": "The Journal of biological chemistry",
    "date": "1999",
    "authors": "Wu J, Zhou L, Tonissen K, Tee R, Artzt K",
    "reference": {
        "type": "PubMed",
        "id": "10506177",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10506177"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q9QYS9-1",
            "protein_name": "KH domain-containing RNA-binding protein QKI",
            "gene_name": "Qki",
            "tax_name": "Mouse"
        }
    ],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9QYS9",
                    "url": "https://www.uniprot.org/uniprot/Q9QYS9"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
    "mutagenesis": [
        {
            "start_pos": 324,
            "end_pos": 324,
            "sequence_org": "R",
            "sequence_mut": "A",
            "comment": "Abolishes nuclear localization; when associated with A-330.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9QYS9",
                    "url": "https://www.uniprot.org/uniprot/Q9QYS9"
                },
                {
                    "database": "PubMed",
                    "id": "10506177",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10506177"
                }
            ],
            "uniprot_canonical_ac": "Q9QYS9-1"
        },
        {
            "start_pos": 328,
            "end_pos": 328,
            "sequence_org": "Y",
            "sequence_mut": "F",
            "comment": "Does not affect nuclear localization.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9QYS9",
                    "url": "https://www.uniprot.org/uniprot/Q9QYS9"
                },
                {
                    "database": "PubMed",
                    "id": "10506177",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10506177"
                }
            ],
            "uniprot_canonical_ac": "Q9QYS9-1"
        },
        {
            "start_pos": 330,
            "end_pos": 330,
            "sequence_org": "R",
            "sequence_mut": "A",
            "comment": "Abolishes nuclear localization; when associated with A-324.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9QYS9",
                    "url": "https://www.uniprot.org/uniprot/Q9QYS9"
                },
                {
                    "database": "PubMed",
                    "id": "10506177",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10506177"
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            ],
            "uniprot_canonical_ac": "Q9QYS9-1"
        },
        {
            "start_pos": 48,
            "end_pos": 48,
            "sequence_org": "E",
            "sequence_mut": "G",
            "comment": "In qk-Kt4; induces embryonic lethality possibly due to its inability to homodimerize.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9QYS9",
                    "url": "https://www.uniprot.org/uniprot/Q9QYS9"
                },
                {
                    "database": "PubMed",
                    "id": "8589716",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/8589716"
                },
                {
                    "database": "PubMed",
                    "id": "10506177",
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                },
                {
                    "database": "PubMed",
                    "id": "9671495",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/9671495"
                },
                {
                    "database": "PubMed",
                    "id": "22982292",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/22982292"
                }
            ],
            "uniprot_canonical_ac": "Q9QYS9-1"
        }
    ],
    "record_id": "pubmed.10506177",
    "abstract": "",
    "glycosylation": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
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