{
    "title": "Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF.",
    "journal": "Blood",
    "date": "1999",
    "authors": "Stomski FC, Dottore M, Winnall W, Guthridge MA, Woodcock J, Bagley CJ, Thomas DT, Andrews RK, Berndt MC, Lopez AF",
    "reference": {
        "type": "PubMed",
        "id": "10477722",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10477722"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "O00459-1",
            "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta",
            "gene_name": "PIK3R2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P15509-1",
            "protein_name": "Granulocyte-macrophage colony-stimulating factor receptor subunit alpha",
            "gene_name": "CSF2RA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q01344-1",
            "protein_name": "Interleukin-5 receptor subunit alpha",
            "gene_name": "IL5RA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P08700-1",
            "protein_name": "Interleukin-3",
            "gene_name": "IL3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P29353-1",
            "protein_name": "SHC-transforming protein 1",
            "gene_name": "SHC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P27986-1",
            "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha",
            "gene_name": "PIK3R1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P51692-1",
            "protein_name": "Signal transducer and activator of transcription 5B",
            "gene_name": "STAT5B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P42338-1",
            "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform",
            "gene_name": "PIK3CB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P26951-1",
            "protein_name": "Interleukin-3 receptor subunit alpha",
            "gene_name": "IL3RA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P32927-1",
            "protein_name": "Cytokine receptor common subunit beta",
            "gene_name": "CSF2RB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P42336-1",
            "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform",
            "gene_name": "PIK3CA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P42229-1",
            "protein_name": "Signal transducer and activator of transcription 5A",
            "gene_name": "STAT5A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04141-1",
            "protein_name": "Granulocyte-macrophage colony-stimulating factor",
            "gene_name": "CSF2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00329-1",
            "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform",
            "gene_name": "PIK3CD",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P29350-1",
            "protein_name": "Tyrosine-protein phosphatase non-receptor type 6",
            "gene_name": "PTPN6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q06124-2",
            "protein_name": "Tyrosine-protein phosphatase non-receptor type 11",
            "gene_name": "PTPN11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92569-1",
            "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma",
            "gene_name": "PIK3R3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O60674-1",
            "protein_name": "Tyrosine-protein kinase JAK2",
            "gene_name": "JAK2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P42680-1",
            "protein_name": "Tyrosine-protein kinase Tec",
            "gene_name": "TEC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P17612-1",
            "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha",
            "gene_name": "PRKACA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P05113-1",
            "protein_name": "Interleukin-5",
            "gene_name": "IL5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P15498-1",
            "protein_name": "Proto-oncogene vav",
            "gene_name": "VAV1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P63104-1",
            "protein_name": "14-3-3 protein zeta/delta",
            "gene_name": "YWHAZ",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O00459",
                    "url": "https://www.uniprot.org/uniprot/O00459"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 585,
            "end_pos": 585,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P32927",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32927"
                },
                {
                    "database": "PubMed",
                    "id": "10477722",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10477722"
                },
                {
                    "database": "PRO",
                    "id": "P32927",
                    "url": "http://purl.obolibrary.org/obo/P32927"
                }
            ],
            "site_lbl": "Ser585",
            "uniprot_canonical_ac": "P32927-1"
        },
        {
            "start_pos": 601,
            "end_pos": 601,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "",
            "evidence": [
                {
                    "database": "IntAct",
                    "id": "P32927",
                    "url": "https://www.ebi.ac.uk/intact/interactors/id:P32927*"
                },
                {
                    "database": "iPTMnet",
                    "id": "P32927",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P32927"
                },
                {
                    "database": "PubMed",
                    "id": "16437163",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/16437163"
                },
                {
                    "database": "PubMed",
                    "id": "10949031",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10949031"
                },
                {
                    "database": "phospho.ELM",
                    "id": "P32927",
                    "url": "http://phospho.elm.eu.org/byAccession/P32927.html"
                },
                {
                    "database": "PRO",
                    "id": "P32927",
                    "url": "http://purl.obolibrary.org/obo/P32927"
                },
                {
                    "database": "PubMed",
                    "id": "10477722",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10477722"
                }
            ],
            "site_lbl": "Ser601",
            "uniprot_canonical_ac": "P32927-1"
        }
    ],
    "record_id": "pubmed.10477722",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "glycation": [],
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