{
    "title": "Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases.",
    "journal": "Molecular and cellular biology",
    "date": "1999",
    "authors": "Blomberg I, Hoffmann I",
    "reference": {
        "type": "PubMed",
        "id": "10454565",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10454565"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P61244-1",
            "protein_name": "Protein max",
            "gene_name": "MAX",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P31751-1",
            "protein_name": "RAC-beta serine/threonine-protein kinase",
            "gene_name": "AKT2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14186-1",
            "protein_name": "Transcription factor Dp-1",
            "gene_name": "TFDP1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30304-1",
            "protein_name": "M-phase inducer phosphatase 1",
            "gene_name": "CDC25A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96GY3-1",
            "protein_name": "Protein lin-37 homolog",
            "gene_name": "LIN37",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O96020-1",
            "protein_name": "G1/S-specific cyclin-E2",
            "gene_name": "CCNE2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P20248-1",
            "protein_name": "Cyclin-A2",
            "gene_name": "CCNA2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TDN4-1",
            "protein_name": "CDK5 and ABL1 enzyme substrate 1",
            "gene_name": "CABLES1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15329-1",
            "protein_name": "Transcription factor E2F5",
            "gene_name": "E2F5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P51946-1",
            "protein_name": "Cyclin-H",
            "gene_name": "CCNH",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P38936-1",
            "protein_name": "Cyclin-dependent kinase inhibitor 1",
            "gene_name": "CDKN1A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P46527-1",
            "protein_name": "Cyclin-dependent kinase inhibitor 1B",
            "gene_name": "CDKN1B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30291-1",
            "protein_name": "Wee1-like protein kinase",
            "gene_name": "WEE1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5TKA1-1",
            "protein_name": "Protein lin-9 homolog",
            "gene_name": "LIN9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P50613-1",
            "protein_name": "Cyclin-dependent kinase 7",
            "gene_name": "CDK7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P51948-1",
            "protein_name": "CDK-activating kinase assembly factor MAT1",
            "gene_name": "MNAT1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01106-2",
            "protein_name": "Myc proto-oncogene protein",
            "gene_name": "MYC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16254-1",
            "protein_name": "Transcription factor E2F4",
            "gene_name": "E2F4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P78396-1",
            "protein_name": "Cyclin-A1",
            "gene_name": "CCNA1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q01094-1",
            "protein_name": "Transcription factor E2F1",
            "gene_name": "E2F1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y243-1",
            "protein_name": "RAC-gamma serine/threonine-protein kinase",
            "gene_name": "AKT3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06400-1",
            "protein_name": "Retinoblastoma-associated protein",
            "gene_name": "RB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UM11-1",
            "protein_name": "Fizzy-related protein homolog",
            "gene_name": "FZR1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6MZP7-1",
            "protein_name": "Protein lin-54 homolog",
            "gene_name": "LIN54",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14188-1",
            "protein_name": "Transcription factor Dp-2",
            "gene_name": "TFDP2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q52LA3-1",
            "protein_name": "Protein lin-52 homolog",
            "gene_name": "LIN52",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q08999-1",
            "protein_name": "Retinoblastoma-like protein 2",
            "gene_name": "RBL2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q09028-1",
            "protein_name": "Histone-binding protein RBBP4",
            "gene_name": "RBBP4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P24941-1",
            "protein_name": "Cyclin-dependent kinase 2",
            "gene_name": "CDK2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30305-1",
            "protein_name": "M-phase inducer phosphatase 2",
            "gene_name": "CDC25B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P31749-1",
            "protein_name": "RAC-alpha serine/threonine-protein kinase",
            "gene_name": "AKT1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P24864-1",
            "protein_name": "G1/S-specific cyclin-E1",
            "gene_name": "CCNE1",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P61244",
                    "url": "https://www.uniprot.org/uniprot/P61244"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10454565",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 32
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}