{
    "title": "Identification, functional characterization, and chromosomal localization of USP15, a novel human ubiquitin-specific protease related to the UNP oncoprotein, and a systematic nomenclature for human ubiquitin-specific proteases.",
    "journal": "Genomics",
    "date": "1999",
    "authors": "Baker RT, Wang XW, Woollatt E, White JA, Sutherland GR",
    "reference": {
        "type": "PubMed",
        "id": "10444327",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10444327"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q15796-1",
            "protein_name": "Mothers against decapentaplegic homolog 2",
            "gene_name": "SMAD2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16186-1",
            "protein_name": "Proteasomal ubiquitin receptor ADRM1",
            "gene_name": "ADRM1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06899-1",
            "protein_name": "Histone H2B type 1-J",
            "gene_name": "H2BC11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q86TJ2-1",
            "protein_name": "Transcriptional adapter 2-beta",
            "gene_name": "TADA2B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49720-1",
            "protein_name": "Proteasome subunit beta type-3",
            "gene_name": "PSMB3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16777-1",
            "protein_name": "Histone H2A type 2-C",
            "gene_name": "H2AC20",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P61289-1",
            "protein_name": "Proteasome activator complex subunit 3",
            "gene_name": "PSME3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9H2K2-1",
            "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
            "gene_name": "TNKS2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A5LHX3-1",
            "protein_name": "Proteasome subunit beta type-11",
            "gene_name": "PSMB11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q06323-1",
            "protein_name": "Proteasome activator complex subunit 1",
            "gene_name": "PSME1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00233-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 9",
            "gene_name": "PSMD9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25963-1",
            "protein_name": "NF-kappa-B inhibitor alpha",
            "gene_name": "NFKBIA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O94826-1",
            "protein_name": "Mitochondrial import receptor subunit TOM70",
            "gene_name": "TOMM70",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NTX7-1",
            "protein_name": "E3 ubiquitin-protein ligase RNF146",
            "gene_name": "RNF146",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62191-1",
            "protein_name": "26S proteasome regulatory subunit 4",
            "gene_name": "PSMC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UK80-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
            "gene_name": "USP21",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P45974-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
            "gene_name": "USP5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16665-1",
            "protein_name": "Hypoxia-inducible factor 1-alpha",
            "gene_name": "HIF1A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25786-1",
            "protein_name": "Proteasome subunit alpha type-1",
            "gene_name": "PSMA1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y4K3-1",
            "protein_name": "TNF receptor-associated factor 6",
            "gene_name": "TRAF6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30304-1",
            "protein_name": "M-phase inducer phosphatase 1",
            "gene_name": "CDC25A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16778-1",
            "protein_name": "Histone H2B type 2-E",
            "gene_name": "H2BC21",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14457-1",
            "protein_name": "Beclin-1",
            "gene_name": "BECN1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y256-1",
            "protein_name": "CAAX prenyl protease 2",
            "gene_name": "RCE1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6R6M4-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
            "gene_name": "USP17L2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "D6R9N7-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
            "gene_name": "USP17L18",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92830-1",
            "protein_name": "Histone acetyltransferase KAT2A",
            "gene_name": "KAT2A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14318-1",
            "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP8",
            "gene_name": "FKBP8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "C9JPN9-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
            "gene_name": "USP17L12",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75528-1",
            "protein_name": "Transcriptional adapter 3",
            "gene_name": "TADA3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "D6RJB6-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
            "gene_name": "USP17L20",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6FI13-1",
            "protein_name": "Histone H2A type 2-A",
            "gene_name": "H2AC18; H2AC19",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9BYX4-1",
            "protein_name": "Interferon-induced helicase C domain-containing protein 1",
            "gene_name": "IFIH1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q0WX57-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
            "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92995-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 13",
            "gene_name": "USP13",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8IUE6-1",
            "protein_name": "Histone H2A type 2-B",
            "gene_name": "H2AC21",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P51784-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
            "gene_name": "USP11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96QV6-1",
            "protein_name": "Histone H2A type 1-A",
            "gene_name": "H2AC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A6NCW0-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
            "gene_name": "USP17L3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q00987-1",
            "protein_name": "E3 ubiquitin-protein ligase Mdm2",
            "gene_name": "MDM2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y277-1",
            "protein_name": "Voltage-dependent anion-selective channel protein 3",
            "gene_name": "VDAC3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q93008-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
            "gene_name": "USP9X",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NQC7-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
            "gene_name": "CYLD",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P23771-1",
            "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
            "gene_name": "GATA3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P35998-1",
            "protein_name": "26S proteasome regulatory subunit 7",
            "gene_name": "PSMC2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25789-1",
            "protein_name": "Proteasome subunit alpha type-4",
            "gene_name": "PSMA4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00231-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 11",
            "gene_name": "PSMD11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99879-1",
            "protein_name": "Histone H2B type 1-M",
            "gene_name": "H2BC14",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P40306-1",
            "protein_name": "Proteasome subunit beta type-10",
            "gene_name": "PSMB10",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q12933-1",
            "protein_name": "TNF receptor-associated factor 2",
            "gene_name": "TRAF2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O43255-1",
            "protein_name": "E3 ubiquitin-protein ligase SIAH2",
            "gene_name": "SIAH2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96RU2-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
            "gene_name": "USP28",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O60814-1",
            "protein_name": "Histone H2B type 1-K",
            "gene_name": "H2BC12",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16401-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 5",
            "gene_name": "PSMD5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62987-1",
            "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
            "gene_name": "UBA52",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y6K9-1",
            "protein_name": "NF-kappa-B essential modulator",
            "gene_name": "IKBKG",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q93079-1",
            "protein_name": "Histone H2B type 1-H",
            "gene_name": "H2BC9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O94966-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19",
            "gene_name": "USP19",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06746-1",
            "protein_name": "DNA polymerase beta",
            "gene_name": "POLB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O95271-1",
            "protein_name": "Poly [ADP-ribose] polymerase tankyrase-1",
            "gene_name": "TNKS",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "D6RCP7-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
            "gene_name": "USP17L19",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P10275-1",
            "protein_name": "Androgen receptor",
            "gene_name": "AR",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P84022-1",
            "protein_name": "Mothers against decapentaplegic homolog 3",
            "gene_name": "SMAD3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P20248-1",
            "protein_name": "Cyclin-A2",
            "gene_name": "CCNA2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6ZVN7-1",
            "protein_name": "Putative protein SEM1, isoform 2",
            "gene_name": "SEM1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92890-2",
            "protein_name": "Ubiquitin recognition factor in ER-associated degradation protein 1",
            "gene_name": "UFD1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UPU5-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24",
            "gene_name": "USP24",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15388-1",
            "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
            "gene_name": "TOMM20",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9H7L9-1",
            "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
            "gene_name": "SUDS3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG48-1",
            "protein_name": "Polyubiquitin-C",
            "gene_name": "UBC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62333-1",
            "protein_name": "26S proteasome regulatory subunit 10B",
            "gene_name": "PSMC6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q7L7L0-1",
            "protein_name": "Histone H2A type 3",
            "gene_name": "H2AC25",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62195-1",
            "protein_name": "26S proteasome regulatory subunit 8",
            "gene_name": "PSMC5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TEY7-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
            "gene_name": "USP33",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P36897-1",
            "protein_name": "TGF-beta receptor type-1",
            "gene_name": "TGFBR1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13485-1",
            "protein_name": "Mothers against decapentaplegic homolog 4",
            "gene_name": "SMAD4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75832-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 10",
            "gene_name": "PSMD10",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P21796-1",
            "protein_name": "Non-selective voltage-gated ion channel VDAC1",
            "gene_name": "VDAC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UL46-1",
            "protein_name": "Proteasome activator complex subunit 2",
            "gene_name": "PSME2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TAF3-1",
            "protein_name": "WD repeat-containing protein 48",
            "gene_name": "WDR48",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62979-1",
            "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
            "gene_name": "RPS27A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96KK5-1",
            "protein_name": "Histone H2A type 1-H",
            "gene_name": "H2AC12",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O43318-1",
            "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
            "gene_name": "MAP3K7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O43303-1",
            "protein_name": "Centriolar coiled-coil protein of 110 kDa",
            "gene_name": "CCP110",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P48556-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
            "gene_name": "PSMD8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28065-1",
            "protein_name": "Proteasome subunit beta type-9",
            "gene_name": "PSMB9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "D6RA61-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
            "gene_name": "USP17L22",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q70CQ2-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
            "gene_name": "USP34",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P51665-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
            "gene_name": "PSMD7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P98177-1",
            "protein_name": "Forkhead box protein O4",
            "gene_name": "FOXO4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P45880-3",
            "protein_name": "Voltage-dependent anion-selective channel protein 2",
            "gene_name": "VDAC2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62807-1",
            "protein_name": "Histone H2B type 1-C/E/F/G/I",
            "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96A08-1",
            "protein_name": "Histone H2B type 1-A",
            "gene_name": "H2BC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15750-1",
            "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1",
            "gene_name": "TAB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9HAU4-1",
            "protein_name": "E3 ubiquitin-protein ligase SMURF2",
            "gene_name": "SMURF2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y265-1",
            "protein_name": "RuvB-like 1",
            "gene_name": "RUVBL1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5QNW6-1",
            "protein_name": "Histone H2B type 2-F",
            "gene_name": "H2BC18",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P60484-1",
            "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
            "gene_name": "PTEN",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P20671-1",
            "protein_name": "Histone H2A type 1-D",
            "gene_name": "H2AC7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UMW8-1",
            "protein_name": "Ubl carboxyl-terminal hydrolase 18",
            "gene_name": "USP18",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P40818-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 8",
            "gene_name": "USP8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O95760-1",
            "protein_name": "Interleukin-33",
            "gene_name": "IL33",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14694-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
            "gene_name": "USP10",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG47-1",
            "protein_name": "Polyubiquitin-B",
            "gene_name": "UBB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O60493-1",
            "protein_name": "Sorting nexin-3",
            "gene_name": "SNX3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04637-1",
            "protein_name": "Cellular tumor antigen p53",
            "gene_name": "TP53",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14997-1",
            "protein_name": "Proteasome activator complex subunit 4",
            "gene_name": "PSME4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96FW1-1",
            "protein_name": "Ubiquitin thioesterase OTUB1",
            "gene_name": "OTUB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49407-1",
            "protein_name": "Beta-arrestin-1",
            "gene_name": "ARRB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92530-1",
            "protein_name": "Proteasome inhibitor PI31 subunit",
            "gene_name": "PSMF1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y4A5-1",
            "protein_name": "Transformation/transcription domain-associated protein",
            "gene_name": "TRRAP",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q12962-1",
            "protein_name": "Transcription initiation factor TFIID subunit 10",
            "gene_name": "TAF10",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "C9JLJ4-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
            "gene_name": "USP17L13",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "C9JJH3-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
            "gene_name": "USP17L10",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q969V5-1",
            "protein_name": "Mitochondrial ubiquitin ligase activator of NFKB 1",
            "gene_name": "MUL1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13489-1",
            "protein_name": "Baculoviral IAP repeat-containing protein 3",
            "gene_name": "BIRC3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00487-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 14",
            "gene_name": "PSMD14",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y4E8-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
            "gene_name": "USP15",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P17980-1",
            "protein_name": "26S proteasome regulatory subunit 6A",
            "gene_name": "PSMC3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28070-1",
            "protein_name": "Proteasome subunit beta type-4",
            "gene_name": "PSMB4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q70CQ1-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 49",
            "gene_name": "USP49",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P33778-1",
            "protein_name": "Histone H2B type 1-B",
            "gene_name": "H2BC3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P60900-1",
            "protein_name": "Proteasome subunit alpha type-6",
            "gene_name": "PSMA6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P23527-1",
            "protein_name": "Histone H2B type 1-O",
            "gene_name": "H2BC17",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28066-1",
            "protein_name": "Proteasome subunit alpha type-5",
            "gene_name": "PSMA5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UHP3-2",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
            "gene_name": "USP25",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A6NCW7-1",
            "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
            "gene_name": "USP17L4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TBZ3-1",
            "protein_name": "WD repeat-containing protein 20",
            "gene_name": "WDR20",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "D6RBQ6-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
            "gene_name": "USP17L17",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P43686-1",
            "protein_name": "26S proteasome regulatory subunit 6B",
            "gene_name": "PSMC4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9HAW4-1",
            "protein_name": "Claspin",
            "gene_name": "CLSPN",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13309-1",
            "protein_name": "S-phase kinase-associated protein 2",
            "gene_name": "SKP2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "D6R901-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
            "gene_name": "USP17L21",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13490-1",
            "protein_name": "Baculoviral IAP repeat-containing protein 2",
            "gene_name": "BIRC2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A8MUK1-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
            "gene_name": "USP17L5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y3E5-1",
            "protein_name": "Peptidyl-tRNA hydrolase 2, mitochondrial",
            "gene_name": "PTRH2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0C7I0-1",
            "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
            "gene_name": "USP17L8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01106-2",
            "protein_name": "Myc proto-oncogene protein",
            "gene_name": "MYC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P55036-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 4",
            "gene_name": "PSMD4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13200-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
            "gene_name": "PSMD2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8N257-1",
            "protein_name": "Histone H2B type 3-B",
            "gene_name": "H2BC26",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q70CQ3-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
            "gene_name": "USP30",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28072-1",
            "protein_name": "Proteasome subunit beta type-6",
            "gene_name": "PSMB6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q93077-1",
            "protein_name": "Histone H2A type 1-C",
            "gene_name": "H2AC6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NZL9-1",
            "protein_name": "Methionine adenosyltransferase 2 subunit beta",
            "gene_name": "MAT2B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "C9JVI0-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
            "gene_name": "USP17L11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9HBM6-1",
            "protein_name": "Transcription initiation factor TFIID subunit 9B",
            "gene_name": "TAF9B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75886-1",
            "protein_name": "Signal transducing adapter molecule 2",
            "gene_name": "STAM2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96K76-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 47",
            "gene_name": "USP47",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UNM6-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
            "gene_name": "PSMD13",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15008-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
            "gene_name": "PSMD6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P78396-1",
            "protein_name": "Cyclin-A1",
            "gene_name": "CCNA1",
            "tax_name": "Human"
        },
        {
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            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 16",
            "gene_name": "USP16",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8IXI2-1",
            "protein_name": "Mitochondrial Rho GTPase 1",
            "gene_name": "RHOT1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9H9J4-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
            "gene_name": "USP42",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "C9J2P7-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
            "gene_name": "USP17L15",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25787-1",
            "protein_name": "Proteasome subunit alpha type-2",
            "gene_name": "PSMA2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99877-1",
            "protein_name": "Histone H2B type 1-N",
            "gene_name": "H2BC15",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P32121-1",
            "protein_name": "Beta-arrestin-2",
            "gene_name": "ARRB2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P13569-1",
            "protein_name": "Cystic fibrosis transmembrane conductance regulator",
            "gene_name": "CFTR",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75604-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2",
            "gene_name": "USP2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00232-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
            "gene_name": "PSMD12",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TAA3-1",
            "protein_name": "Proteasome subunit alpha-type 8",
            "gene_name": "PSMA8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y2K6-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 20",
            "gene_name": "USP20",
            "tax_name": "Human"
        },
        {
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            "protein_name": "Protein Mdm4",
            "gene_name": "MDM4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5XPI4-1",
            "protein_name": "E3 ubiquitin-protein ligase RNF123",
            "gene_name": "RNF123",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q7RTZ2-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
            "gene_name": "USP17L1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q12834-1",
            "protein_name": "Cell division cycle protein 20 homolog",
            "gene_name": "CDC20",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28062-1",
            "protein_name": "Proteasome subunit beta type-8",
            "gene_name": "PSMB8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O14964-1",
            "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate",
            "gene_name": "HGS",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49721-1",
            "protein_name": "Proteasome subunit beta type-2",
            "gene_name": "PSMB2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O15265-1",
            "protein_name": "Ataxin-7",
            "gene_name": "ATXN7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0C0S8-1",
            "protein_name": "Histone H2A type 1",
            "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y2T1-1",
            "protein_name": "Axin-2",
            "gene_name": "AXIN2",
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        },
        {
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            "protein_name": "DNA damage-binding protein 2",
            "gene_name": "DDB2",
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            "uniprot_canonical_ac": "Q15797-1",
            "protein_name": "Mothers against decapentaplegic homolog 1",
            "gene_name": "SMAD1",
            "tax_name": "Human"
        },
        {
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            "protein_name": "Proteasome subunit beta type-5",
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            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "O75317-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
            "gene_name": "USP12",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P54578-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
            "gene_name": "USP14",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O95786-1",
            "protein_name": "Antiviral innate immune response receptor RIG-I",
            "gene_name": "DDX58; RIGI",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99880-1",
            "protein_name": "Histone H2B type 1-L",
            "gene_name": "H2BC13",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q86T82-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
            "gene_name": "USP37",
            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "Q86UV5-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P58876-1",
            "protein_name": "Histone H2B type 1-D",
            "gene_name": "H2BC5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99460-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
            "gene_name": "PSMD1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9BXU7-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
            "gene_name": "USP26",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O15105-1",
            "protein_name": "Mothers against decapentaplegic homolog 7",
            "gene_name": "SMAD7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P14735-1",
            "protein_name": "Insulin-degrading enzyme",
            "gene_name": "IDE",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P07550-1",
            "protein_name": "Beta-2 adrenergic receptor",
            "gene_name": "ADRB2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99436-1",
            "protein_name": "Proteasome subunit beta type-7",
            "gene_name": "PSMB7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99878-1",
            "protein_name": "Histone H2A type 1-J",
            "gene_name": "H2AC14",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25788-1",
            "protein_name": "Proteasome subunit alpha type-3",
            "gene_name": "PSMA3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q93009-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 7",
            "gene_name": "USP7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9H0E7-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
            "gene_name": "USP44",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O43242-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
            "gene_name": "PSMD3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14145-1",
            "protein_name": "Kelch-like ECH-associated protein 1",
            "gene_name": "KEAP1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TEB7-1",
            "protein_name": "E3 ubiquitin-protein ligase RNF128",
            "gene_name": "RNF128",
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        },
        {
            "uniprot_canonical_ac": "Q13546-1",
            "protein_name": "Receptor-interacting serine/threonine-protein kinase 1",
            "gene_name": "RIPK1",
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        },
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            "uniprot_canonical_ac": "Q13107-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4",
            "gene_name": "USP4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P20618-1",
            "protein_name": "Proteasome subunit beta type-1",
            "gene_name": "PSMB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UPT9-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 22",
            "gene_name": "USP22",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O14818-1",
            "protein_name": "Proteasome subunit alpha type-7",
            "gene_name": "PSMA7",
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        },
        {
            "uniprot_canonical_ac": "Q9Y6I4-1",
            "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
            "gene_name": "USP3",
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        },
        {
            "uniprot_canonical_ac": "O15169-1",
            "protein_name": "Axin-1",
            "gene_name": "AXIN1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04908-1",
            "protein_name": "Histone H2A type 1-B/E",
            "gene_name": "H2AC4; H2AC8",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q15796",
                    "url": "https://www.uniprot.org/uniprot/Q15796"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10444327",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
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    "phosphorylation": [],
    "glycation": [],
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