{
    "title": "Primary structure and expression analysis of human UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase, the bifunctional enzyme in neuraminic acid biosynthesis.",
    "journal": "FEBS letters",
    "date": "1999",
    "authors": "Lucka L, Krause M, Danker K, Reutter W, Horstkorte R",
    "reference": {
        "type": "PubMed",
        "id": "10431835",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10431835"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q8NDV1-1",
            "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3",
            "gene_name": "ST6GALNAC3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y223-1",
            "protein_name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase",
            "gene_name": "GNE",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P61647-1",
            "protein_name": "Alpha-2,8-sialyltransferase 8F",
            "gene_name": "ST8SIA6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16842-1",
            "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",
            "gene_name": "ST3GAL2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P15907-1",
            "protein_name": "Beta-galactoside alpha-2,6-sialyltransferase 1",
            "gene_name": "ST6GAL1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8WWR8-1",
            "protein_name": "Sialidase-4",
            "gene_name": "NEU4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92187-1",
            "protein_name": "CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase",
            "gene_name": "ST8SIA4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UJ37-1",
            "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",
            "gene_name": "ST6GALNAC2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99519-1",
            "protein_name": "Sialidase-1",
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O15466-1",
            "protein_name": "Alpha-2,8-sialyltransferase 8E",
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        },
        {
            "uniprot_canonical_ac": "Q11203-1",
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        },
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        },
        {
            "uniprot_canonical_ac": "O43173-1",
            "protein_name": "Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3",
            "gene_name": "ST8SIA3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NR45-1",
            "protein_name": "Sialic acid synthase",
            "gene_name": "NANS",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P16278-1",
            "protein_name": "Beta-galactosidase",
            "gene_name": "GLB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q11201-1",
            "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1",
            "gene_name": "ST3GAL1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TBE9-1",
            "protein_name": "N-acylneuraminate-9-phosphatase",
            "gene_name": "NANP",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UQ49-1",
            "protein_name": "Sialidase-3",
            "gene_name": "NEU3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8NFW8-1",
            "protein_name": "N-acylneuraminate cytidylyltransferase",
            "gene_name": "CMAS",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P10619-1",
            "protein_name": "Lysosomal protective protein",
            "gene_name": "CTSA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P78382-1",
            "protein_name": "CMP-sialic acid transporter",
            "gene_name": "SLC35A1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NSC7-1",
            "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",
            "gene_name": "ST6GALNAC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NRA2-1",
            "protein_name": "Sialin",
            "gene_name": "SLC17A5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92186-1",
            "protein_name": "Alpha-2,8-sialyltransferase 8B",
            "gene_name": "ST8SIA2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9BXD5-1",
            "protein_name": "N-acetylneuraminate lyase",
            "gene_name": "NPL",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96JF0-1",
            "protein_name": "Beta-galactoside alpha-2,6-sialyltransferase 2",
            "gene_name": "ST6GAL2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q11206-1",
            "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",
            "gene_name": "ST3GAL4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y274-1",
            "protein_name": "Type 2 lactosamine alpha-2,3-sialyltransferase",
            "gene_name": "ST3GAL6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y3R4-1",
            "protein_name": "Sialidase-2",
            "gene_name": "NEU2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9BVH7-1",
            "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",
            "gene_name": "ST6GALNAC5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UNP4-1",
            "protein_name": "Lactosylceramide alpha-2,3-sialyltransferase",
            "gene_name": "ST3GAL5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9H4F1-1",
            "protein_name": "Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase",
            "gene_name": "ST6GALNAC4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q969X2-1",
            "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",
            "gene_name": "ST6GALNAC6",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8NDV1",
                    "url": "https://www.uniprot.org/uniprot/Q8NDV1"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10431835",
    "abstract": "",
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    "mutagenesis": [],
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