{
    "title": "Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins.",
    "journal": "The Journal of biological chemistry",
    "date": "1999",
    "authors": "Espenshade PJ, Cheng D, Goldstein JL, Brown MS",
    "reference": {
        "type": "PubMed",
        "id": "10428864",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10428864"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q9Y5U4-1",
            "protein_name": "Insulin-induced gene 2 protein",
            "gene_name": "INSIG2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O95486-1",
            "protein_name": "Protein transport protein Sec24A",
            "gene_name": "SEC24A",
            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "Q15436-1",
            "protein_name": "Protein transport protein Sec23A",
            "gene_name": "SEC23A",
            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "O94855-1",
            "protein_name": "Protein transport protein Sec24D",
            "gene_name": "SEC24D",
            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "O15503-1",
            "protein_name": "Insulin-induced gene 1 protein",
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            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "O43462-1",
            "protein_name": "Membrane-bound transcription factor site-2 protease",
            "gene_name": "MBTPS2",
            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "P53992-1",
            "protein_name": "Protein transport protein Sec24C",
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y6B6-1",
            "protein_name": "Small COPII coat GTPase SAR1B",
            "gene_name": "SAR1B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62826-1",
            "protein_name": "GTP-binding nuclear protein Ran",
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        },
        {
            "uniprot_canonical_ac": "Q12770-1",
            "protein_name": "Sterol regulatory element-binding protein cleavage-activating protein",
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            "tax_name": "Human"
        },
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        },
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        },
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    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9Y5U4",
                    "url": "https://www.uniprot.org/uniprot/Q9Y5U4"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10428864",
    "abstract": "",
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