{
    "title": "FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells.",
    "journal": "The Journal of biological chemistry",
    "date": "1999",
    "authors": "Raab M, Kang H, da Silva A, Zhu X, Rudd CE",
    "reference": {
        "type": "PubMed",
        "id": "10409671",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10409671"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "O15117-1",
            "protein_name": "FYN-binding protein 1",
            "gene_name": "FYB1",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O15117",
                    "url": "https://www.uniprot.org/uniprot/O15117"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 595,
            "end_pos": 595,
            "kinase_uniprot_canonical_ac": "P06241-1",
            "kinase_gene_name": "FYN",
            "residue": "Tyr",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "O15117",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O15117"
                },
                {
                    "database": "PubMed",
                    "id": "10570256",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10570256"
                },
                {
                    "database": "phospho.ELM",
                    "id": "O15117",
                    "url": "http://phospho.elm.eu.org/byAccession/O15117.html"
                },
                {
                    "database": "PubMed",
                    "id": "10409671",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10409671"
                },
                {
                    "database": "PubMed",
                    "id": "20661443",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/20661443"
                },
                {
                    "database": "PubMed",
                    "id": "26246585",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/26246585"
                }
            ],
            "site_lbl": "Tyr595",
            "uniprot_canonical_ac": "O15117-1"
        },
        {
            "start_pos": 625,
            "end_pos": 625,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "",
            "evidence": [
                {
                    "database": "IntAct",
                    "id": "O15117",
                    "url": "https://www.ebi.ac.uk/intact/interactors/id:O15117*"
                },
                {
                    "database": "iPTMnet",
                    "id": "O15117",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O15117"
                },
                {
                    "database": "PubMed",
                    "id": "10409671",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10409671"
                }
            ],
            "site_lbl": "Tyr625",
            "uniprot_canonical_ac": "O15117-1"
        },
        {
            "start_pos": 651,
            "end_pos": 651,
            "kinase_uniprot_canonical_ac": "P06241-1",
            "kinase_gene_name": "FYN",
            "residue": "Tyr",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "O15117",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O15117"
                },
                {
                    "database": "PubMed",
                    "id": "10570256",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10570256"
                },
                {
                    "database": "phospho.ELM",
                    "id": "O15117",
                    "url": "http://phospho.elm.eu.org/byAccession/O15117.html"
                },
                {
                    "database": "PubMed",
                    "id": "10409671",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10409671"
                },
                {
                    "database": "PubMed",
                    "id": "20661443",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/20661443"
                },
                {
                    "database": "PubMed",
                    "id": "26246585",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/26246585"
                }
            ],
            "site_lbl": "Tyr651",
            "uniprot_canonical_ac": "O15117-1"
        }
    ],
    "record_id": "pubmed.10409671",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 3
                },
                {
                    "field": "total_sites",
                    "count": 3
                }
            ],
            "sort_fields": [
                "start_pos",
                "end_pos",
                "kinase_uniprot_canonical_ac",
                "kinase_gene_name",
                "residue",
                "comment",
                "site_lbl",
                "uniprot_canonical_ac"
            ]
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}