{
    "title": "Tyrosine phosphorylation enhances the SH2 domain-binding activity of Bcr and inhibits Bcr interaction with 14-3-3 proteins.",
    "journal": "Cellular signalling",
    "date": "1999",
    "authors": "Peters KL, Smithgall TE",
    "reference": {
        "type": "PubMed",
        "id": "10405761",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10405761"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P11274-1",
            "protein_name": "Breakpoint cluster region protein",
            "gene_name": "BCR",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P11274",
                    "url": "https://www.uniprot.org/uniprot/P11274"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 177,
            "end_pos": 177,
            "kinase_uniprot_canonical_ac": "P07332-1",
            "kinase_gene_name": "FES",
            "residue": "Tyr",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P11274",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11274"
                },
                {
                    "database": "PubMed",
                    "id": "12522270",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/12522270"
                },
                {
                    "database": "PubMed",
                    "id": "16497976",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/16497976"
                },
                {
                    "database": "PubMed",
                    "id": "8955135",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/8955135"
                },
                {
                    "database": "PubMed",
                    "id": "9178913",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/9178913"
                },
                {
                    "database": "PubMed",
                    "id": "9407116",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/9407116"
                },
                {
                    "database": "PubMed",
                    "id": "15302586",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/15302586"
                },
                {
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                    "url": "http://phospho.elm.eu.org/byAccession/P11274.html"
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                    "database": "PubMed",
                    "id": "10405761",
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            ],
            "site_lbl": "Tyr177",
            "uniprot_canonical_ac": "P11274-1"
        }
    ],
    "record_id": "pubmed.10405761",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "glycation": [],
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