{
    "title": "Evidence for functional conservation of a mammalian homologue of the light-responsive plant protein COP1.",
    "journal": "Current biology : CB",
    "date": "1999",
    "authors": "Wang H, Kang D, Deng XW, Wei N",
    "reference": {
        "type": "PubMed",
        "id": "10395541",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10395541"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q9R1A8-1",
            "protein_name": "E3 ubiquitin-protein ligase COP1",
            "gene_name": "Cop1",
            "tax_name": "Mouse"
        }
    ],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9R1A8",
                    "url": "https://www.uniprot.org/uniprot/Q9R1A8"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
    "mutagenesis": [
        {
            "start_pos": 113,
            "end_pos": 114,
            "sequence_org": "RK",
            "sequence_mut": "SN",
            "comment": "Abolishes nuclear localization.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9R1A8",
                    "url": "https://www.uniprot.org/uniprot/Q9R1A8"
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                    "id": "10395541",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10395541"
                }
            ],
            "uniprot_canonical_ac": "Q9R1A8-1"
        },
        {
            "start_pos": 197,
            "end_pos": 201,
            "sequence_org": "KQKQR",
            "sequence_mut": "NQNQS",
            "comment": "Does not affect the subcellular localization.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9R1A8",
                    "url": "https://www.uniprot.org/uniprot/Q9R1A8"
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                {
                    "database": "PubMed",
                    "id": "10395541",
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                }
            ],
            "uniprot_canonical_ac": "Q9R1A8-1"
        },
        {
            "start_pos": 205,
            "end_pos": 208,
            "sequence_org": "KRFK",
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            "comment": "Abolishes nuclear localization.",
            "evidence": [
                {
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                    "id": "Q9R1A8",
                    "url": "https://www.uniprot.org/uniprot/Q9R1A8"
                },
                {
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                    "id": "10395541",
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                }
            ],
            "uniprot_canonical_ac": "Q9R1A8-1"
        },
        {
            "start_pos": 244,
            "end_pos": 246,
            "sequence_org": "LEL",
            "sequence_mut": "AEA",
            "comment": "Abolishes nuclear export.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9R1A8",
                    "url": "https://www.uniprot.org/uniprot/Q9R1A8"
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            ],
            "uniprot_canonical_ac": "Q9R1A8-1"
        },
        {
            "start_pos": 358,
            "end_pos": 360,
            "sequence_org": "RRK",
            "sequence_mut": "SRT",
            "comment": "Abolishes the nuclear speckle localization but not the nuclear localization.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9R1A8",
                    "url": "https://www.uniprot.org/uniprot/Q9R1A8"
                },
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                }
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            "uniprot_canonical_ac": "Q9R1A8-1"
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    ],
    "record_id": "pubmed.10395541",
    "abstract": "",
    "glycosylation": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
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