{
    "title": "The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN.",
    "journal": "The Journal of cell biology",
    "date": "1999",
    "authors": "Heyninck K, De Valck D, Vanden Berghe W, Van Criekinge W, Contreras R, Fiers W, Haegeman G, Beyaert R",
    "reference": {
        "type": "PubMed",
        "id": "10385526",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10385526"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "O43353-1",
            "protein_name": "Receptor-interacting serine/threonine-protein kinase 2",
            "gene_name": "RIPK2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P61586-1",
            "protein_name": "Transforming protein RhoA",
            "gene_name": "RHOA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y4K3-1",
            "protein_name": "TNF receptor-associated factor 6",
            "gene_name": "TRAF6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9BYX4-1",
            "protein_name": "Interferon-induced helicase C domain-containing protein 1",
            "gene_name": "IFIH1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96KP6-1",
            "protein_name": "TNFAIP3-interacting protein 3",
            "gene_name": "TNIP3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62987-1",
            "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
            "gene_name": "UBA52",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y6K9-1",
            "protein_name": "NF-kappa-B essential modulator",
            "gene_name": "IKBKG",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9HC29-1",
            "protein_name": "Nucleotide-binding oligomerization domain-containing protein 2",
            "gene_name": "NOD2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8IUD6-1",
            "protein_name": "E3 ubiquitin-protein ligase RNF135",
            "gene_name": "RNF135",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06493-1",
            "protein_name": "Cyclin-dependent kinase 1",
            "gene_name": "CDK1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9C037-1",
            "protein_name": "E3 ubiquitin-protein ligase TRIM4",
            "gene_name": "TRIM4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG48-1",
            "protein_name": "Polyubiquitin-C",
            "gene_name": "UBC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P03372-1",
            "protein_name": "Estrogen receptor",
            "gene_name": "ESR1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62979-1",
            "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
            "gene_name": "RPS27A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P51668-1",
            "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
            "gene_name": "UBE2D1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96G74-1",
            "protein_name": "OTU domain-containing protein 5",
            "gene_name": "OTUD5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13114-1",
            "protein_name": "TNF receptor-associated factor 3",
            "gene_name": "TRAF3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25054-1",
            "protein_name": "Adenomatous polyposis coli protein",
            "gene_name": "APC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14258-1",
            "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25",
            "gene_name": "TRIM25",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P60484-1",
            "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
            "gene_name": "PTEN",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15025-1",
            "protein_name": "TNFAIP3-interacting protein 1",
            "gene_name": "TNIP1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG47-1",
            "protein_name": "Polyubiquitin-B",
            "gene_name": "UBB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04637-1",
            "protein_name": "Cellular tumor antigen p53",
            "gene_name": "TP53",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96FW1-1",
            "protein_name": "Ubiquitin thioesterase OTUB1",
            "gene_name": "OTUB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q60769-1",
            "protein_name": "Tumor necrosis factor alpha-induced protein 3",
            "gene_name": "Tnfaip3",
            "tax_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9UGI0-1",
            "protein_name": "Ubiquitin thioesterase ZRANB1",
            "gene_name": "ZRANB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96DC9-1",
            "protein_name": "Ubiquitin thioesterase OTUB2",
            "gene_name": "OTUB2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96JH7-1",
            "protein_name": "Deubiquitinating protein VCPIP1",
            "gene_name": "VCPIP1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5T2D3-1",
            "protein_name": "OTU domain-containing protein 3",
            "gene_name": "OTUD3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y239-1",
            "protein_name": "Nucleotide-binding oligomerization domain-containing protein 1",
            "gene_name": "NOD1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q7Z434-1",
            "protein_name": "Mitochondrial antiviral-signaling protein",
            "gene_name": "MAVS",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6GQQ9-1",
            "protein_name": "OTU domain-containing protein 7B",
            "gene_name": "OTUD7B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9WUU8-1",
            "protein_name": "TNFAIP3-interacting protein 1",
            "gene_name": "Tnip1",
            "tax_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "O95786-1",
            "protein_name": "Antiviral innate immune response receptor RIG-I",
            "gene_name": "DDX58; RIGI",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P55072-1",
            "protein_name": "Transitional endoplasmic reticulum ATPase",
            "gene_name": "VCP",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TE49-1",
            "protein_name": "OTU domain-containing protein 7A",
            "gene_name": "OTUD7A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8NFZ5-1",
            "protein_name": "TNFAIP3-interacting protein 2",
            "gene_name": "TNIP2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TEB7-1",
            "protein_name": "E3 ubiquitin-protein ligase RNF128",
            "gene_name": "RNF128",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13546-1",
            "protein_name": "Receptor-interacting serine/threonine-protein kinase 1",
            "gene_name": "RIPK1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P21580-1",
            "protein_name": "Tumor necrosis factor alpha-induced protein 3",
            "gene_name": "TNFAIP3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5VVQ6-1",
            "protein_name": "Ubiquitin thioesterase OTU1",
            "gene_name": "YOD1",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O43353",
                    "url": "https://www.uniprot.org/uniprot/O43353"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10385526",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 41
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}
