{
    "title": "A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells.",
    "journal": "Molecular and cellular biology",
    "date": "1999",
    "authors": "Kumagai H, Sato N, Yamada M, Mahony D, Seghezzi W, Lees E, Arai K, Masai H",
    "reference": {
        "type": "PubMed",
        "id": "10373557",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10373557"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q9H211-1",
            "protein_name": "DNA replication factor Cdt1",
            "gene_name": "CDT1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99741-1",
            "protein_name": "Cell division control protein 6 homolog",
            "gene_name": "CDC6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49736-1",
            "protein_name": "DNA replication licensing factor MCM2",
            "gene_name": "MCM2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75419-1",
            "protein_name": "Cell division control protein 45 homolog",
            "gene_name": "CDC45",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14566-1",
            "protein_name": "DNA replication licensing factor MCM6",
            "gene_name": "MCM6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P09884-1",
            "protein_name": "DNA polymerase alpha catalytic subunit",
            "gene_name": "POLA1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P27694-1",
            "protein_name": "Replication protein A 70 kDa DNA-binding subunit",
            "gene_name": "RPA1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75496-1",
            "protein_name": "Geminin",
            "gene_name": "GMNN",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13415-1",
            "protein_name": "Origin recognition complex subunit 1",
            "gene_name": "ORC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P33991-1",
            "protein_name": "DNA replication licensing factor MCM4",
            "gene_name": "MCM4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13156-1",
            "protein_name": "Replication protein A 30 kDa subunit",
            "gene_name": "RPA4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NRF9-1",
            "protein_name": "DNA polymerase epsilon subunit 3",
            "gene_name": "POLE3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P35244-1",
            "protein_name": "Replication protein A 14 kDa subunit",
            "gene_name": "RPA3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P33993-1",
            "protein_name": "DNA replication licensing factor MCM7",
            "gene_name": "MCM7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49643-1",
            "protein_name": "DNA primase large subunit",
            "gene_name": "PRIM2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25205-1",
            "protein_name": "DNA replication licensing factor MCM3",
            "gene_name": "MCM3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q07864-1",
            "protein_name": "DNA polymerase epsilon catalytic subunit A",
            "gene_name": "POLE",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y5N6-1",
            "protein_name": "Origin recognition complex subunit 6",
            "gene_name": "ORC6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O43913-1",
            "protein_name": "Origin recognition complex subunit 5",
            "gene_name": "ORC5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O43929-1",
            "protein_name": "Origin recognition complex subunit 4",
            "gene_name": "ORC4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UBU7-1",
            "protein_name": "Protein DBF4 homolog A",
            "gene_name": "DBF4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14181-1",
            "protein_name": "DNA polymerase alpha subunit B",
            "gene_name": "POLA2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00311-1",
            "protein_name": "Cell division cycle 7-related protein kinase",
            "gene_name": "CDC7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NR33-1",
            "protein_name": "DNA polymerase epsilon subunit 4",
            "gene_name": "POLE4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49642-1",
            "protein_name": "DNA primase small subunit",
            "gene_name": "PRIM1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q7L590-1",
            "protein_name": "Protein MCM10 homolog",
            "gene_name": "MCM10",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P33992-1",
            "protein_name": "DNA replication licensing factor MCM5",
            "gene_name": "MCM5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13416-1",
            "protein_name": "Origin recognition complex subunit 2",
            "gene_name": "ORC2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UBD5-1",
            "protein_name": "Origin recognition complex subunit 3",
            "gene_name": "ORC3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P24941-1",
            "protein_name": "Cyclin-dependent kinase 2",
            "gene_name": "CDK2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UJA3-1",
            "protein_name": "DNA helicase MCM8",
            "gene_name": "MCM8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P56282-1",
            "protein_name": "DNA polymerase epsilon subunit 2",
            "gene_name": "POLE2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P15927-1",
            "protein_name": "Replication protein A 32 kDa subunit",
            "gene_name": "RPA2",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9H211",
                    "url": "https://www.uniprot.org/uniprot/Q9H211"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10373557",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 33
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}