{
    "title": "Analysis of tyrosine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22.",
    "journal": "The Journal of biological chemistry",
    "date": "1999",
    "authors": "Yohannan J, Wienands J, Coggeshall KM, Justement LB",
    "reference": {
        "type": "PubMed",
        "id": "10373493",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10373493"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P35329-1",
            "protein_name": "B-cell receptor CD22",
            "gene_name": "Cd22",
            "tax_name": "Mouse"
        }
    ],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P35329",
                    "url": "https://www.uniprot.org/uniprot/P35329"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
    "mutagenesis": [
        {
            "start_pos": 828,
            "end_pos": 828,
            "sequence_org": "Y",
            "sequence_mut": "F",
            "comment": "Abolishes binding to GRB2.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P35329",
                    "url": "https://www.uniprot.org/uniprot/P35329"
                },
                {
                    "database": "PubMed",
                    "id": "10373493",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10373493"
                }
            ],
            "uniprot_canonical_ac": "P35329-1"
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 783,
            "end_pos": 783,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P35329",
                    "url": "https://www.uniprot.org/uniprot/P35329"
                },
                {
                    "database": "PubMed",
                    "id": "10373493",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10373493"
                },
                {
                    "database": "IntAct",
                    "id": "P35329",
                    "url": "https://www.ebi.ac.uk/intact/interactors/id:P35329*"
                },
                {
                    "database": "iPTMnet",
                    "id": "P35329",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35329"
                },
                {
                    "database": "PubMed",
                    "id": "9890995",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/9890995"
                }
            ],
            "site_lbl": "Tyr783",
            "uniprot_canonical_ac": "P35329-1"
        },
        {
            "start_pos": 828,
            "end_pos": 828,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P35329",
                    "url": "https://www.uniprot.org/uniprot/P35329"
                },
                {
                    "database": "PubMed",
                    "id": "10373493",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10373493"
                },
                {
                    "database": "IntAct",
                    "id": "P35329",
                    "url": "https://www.ebi.ac.uk/intact/interactors/id:P35329*"
                },
                {
                    "database": "iPTMnet",
                    "id": "P35329",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35329"
                },
                {
                    "database": "PubMed",
                    "id": "11551923",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/11551923"
                }
            ],
            "site_lbl": "Tyr828",
            "uniprot_canonical_ac": "P35329-1"
        },
        {
            "start_pos": 843,
            "end_pos": 843,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P35329",
                    "url": "https://www.uniprot.org/uniprot/P35329"
                },
                {
                    "database": "PubMed",
                    "id": "10373493",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10373493"
                },
                {
                    "database": "IntAct",
                    "id": "P35329",
                    "url": "https://www.ebi.ac.uk/intact/interactors/id:P35329*"
                },
                {
                    "database": "iPTMnet",
                    "id": "P35329",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35329"
                },
                {
                    "database": "PubMed",
                    "id": "11551923",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/11551923"
                },
                {
                    "database": "PubMed",
                    "id": "9890995",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/9890995"
                }
            ],
            "site_lbl": "Tyr843",
            "uniprot_canonical_ac": "P35329-1"
        },
        {
            "start_pos": 863,
            "end_pos": 863,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P35329",
                    "url": "https://www.uniprot.org/uniprot/P35329"
                },
                {
                    "database": "PubMed",
                    "id": "10373493",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10373493"
                },
                {
                    "database": "IntAct",
                    "id": "P35329",
                    "url": "https://www.ebi.ac.uk/intact/interactors/id:P35329*"
                },
                {
                    "database": "iPTMnet",
                    "id": "P35329",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35329"
                },
                {
                    "database": "PubMed",
                    "id": "11551923",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/11551923"
                },
                {
                    "database": "PubMed",
                    "id": "9890995",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/9890995"
                }
            ],
            "site_lbl": "Tyr863",
            "uniprot_canonical_ac": "P35329-1"
        }
    ],
    "record_id": "pubmed.10373493",
    "abstract": "",
    "glycosylation": [],
    "snv": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 4
                },
                {
                    "field": "total_sites",
                    "count": 4
                }
            ],
            "sort_fields": [
                "start_pos",
                "end_pos",
                "kinase_uniprot_canonical_ac",
                "kinase_gene_name",
                "residue",
                "comment",
                "site_lbl",
                "uniprot_canonical_ac"
            ]
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}