{
    "title": "Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A.",
    "journal": "Science (New York, N.Y.)",
    "date": "1999",
    "authors": "Seeling JM, Miller JR, Gil R, Moon RT, White R, Virshup DM",
    "reference": {
        "type": "PubMed",
        "id": "10092233",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10092233"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P49720-1",
            "protein_name": "Proteasome subunit beta type-3",
            "gene_name": "PSMB3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P61289-1",
            "protein_name": "Proteasome activator complex subunit 3",
            "gene_name": "PSME3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13362-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform",
            "gene_name": "PPP2R5C",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A5LHX3-1",
            "protein_name": "Proteasome subunit beta type-11",
            "gene_name": "PSMB11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q06323-1",
            "protein_name": "Proteasome activator complex subunit 1",
            "gene_name": "PSME1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00233-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 9",
            "gene_name": "PSMD9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62191-1",
            "protein_name": "26S proteasome regulatory subunit 4",
            "gene_name": "PSMC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49841-1",
            "protein_name": "Glycogen synthase kinase-3 beta",
            "gene_name": "GSK3B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25786-1",
            "protein_name": "Proteasome subunit alpha type-1",
            "gene_name": "PSMA1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15173-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform",
            "gene_name": "PPP2R5B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14738-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform",
            "gene_name": "PPP2R5D",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P35998-1",
            "protein_name": "26S proteasome regulatory subunit 7",
            "gene_name": "PSMC2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25789-1",
            "protein_name": "Proteasome subunit alpha type-4",
            "gene_name": "PSMA4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00231-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 11",
            "gene_name": "PSMD11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P40306-1",
            "protein_name": "Proteasome subunit beta type-10",
            "gene_name": "PSMB10",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16401-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 5",
            "gene_name": "PSMD5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62987-1",
            "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
            "gene_name": "UBA52",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P48729-1",
            "protein_name": "Casein kinase I isoform alpha",
            "gene_name": "CSNK1A1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6ZVN7-1",
            "protein_name": "Putative protein SEM1, isoform 2",
            "gene_name": "SEM1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30153-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform",
            "gene_name": "PPP2R1A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG48-1",
            "protein_name": "Polyubiquitin-C",
            "gene_name": "UBC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62333-1",
            "protein_name": "26S proteasome regulatory subunit 10B",
            "gene_name": "PSMC6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62195-1",
            "protein_name": "26S proteasome regulatory subunit 8",
            "gene_name": "PSMC5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75832-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 10",
            "gene_name": "PSMD10",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UL46-1",
            "protein_name": "Proteasome activator complex subunit 2",
            "gene_name": "PSME2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13616-1",
            "protein_name": "Cullin-1",
            "gene_name": "CUL1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62979-1",
            "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
            "gene_name": "RPS27A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P48556-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
            "gene_name": "PSMD8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28065-1",
            "protein_name": "Proteasome subunit beta type-9",
            "gene_name": "PSMB9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P51665-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
            "gene_name": "PSMD7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5JTC6-1",
            "protein_name": "APC membrane recruitment protein 1",
            "gene_name": "AMER1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25054-1",
            "protein_name": "Adenomatous polyposis coli protein",
            "gene_name": "APC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG47-1",
            "protein_name": "Polyubiquitin-B",
            "gene_name": "UBB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14997-1",
            "protein_name": "Proteasome activator complex subunit 4",
            "gene_name": "PSME4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92530-1",
            "protein_name": "Proteasome inhibitor PI31 subunit",
            "gene_name": "PSMF1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00487-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 14",
            "gene_name": "PSMD14",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P17980-1",
            "protein_name": "26S proteasome regulatory subunit 6A",
            "gene_name": "PSMC3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28070-1",
            "protein_name": "Proteasome subunit beta type-4",
            "gene_name": "PSMB4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P60900-1",
            "protein_name": "Proteasome subunit alpha type-6",
            "gene_name": "PSMA6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28066-1",
            "protein_name": "Proteasome subunit alpha type-5",
            "gene_name": "PSMA5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P43686-1",
            "protein_name": "26S proteasome regulatory subunit 6B",
            "gene_name": "PSMC4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16537-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform",
            "gene_name": "PPP2R5E",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UGI0-1",
            "protein_name": "Ubiquitin thioesterase ZRANB1",
            "gene_name": "ZRANB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P55036-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 4",
            "gene_name": "PSMD4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13200-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
            "gene_name": "PSMD2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28072-1",
            "protein_name": "Proteasome subunit beta type-6",
            "gene_name": "PSMB6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UNM6-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
            "gene_name": "PSMD13",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15008-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
            "gene_name": "PSMD6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P63208-1",
            "protein_name": "S-phase kinase-associated protein 1",
            "gene_name": "SKP1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62877-1",
            "protein_name": "E3 ubiquitin-protein ligase RBX1",
            "gene_name": "RBX1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25787-1",
            "protein_name": "Proteasome subunit alpha type-2",
            "gene_name": "PSMA2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P67775-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform",
            "gene_name": "PPP2CA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00232-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
            "gene_name": "PSMD12",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8TAA3-1",
            "protein_name": "Proteasome subunit alpha-type 8",
            "gene_name": "PSMA8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28062-1",
            "protein_name": "Proteasome subunit beta type-8",
            "gene_name": "PSMB8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49721-1",
            "protein_name": "Proteasome subunit beta type-2",
            "gene_name": "PSMB2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28074-1",
            "protein_name": "Proteasome subunit beta type-5",
            "gene_name": "PSMB5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30154-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform",
            "gene_name": "PPP2R1B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99460-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
            "gene_name": "PSMD1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99436-1",
            "protein_name": "Proteasome subunit beta type-7",
            "gene_name": "PSMB7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25788-1",
            "protein_name": "Proteasome subunit alpha type-3",
            "gene_name": "PSMA3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O43242-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
            "gene_name": "PSMD3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62714-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform",
            "gene_name": "PPP2CB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P20618-1",
            "protein_name": "Proteasome subunit beta type-1",
            "gene_name": "PSMB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15172-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform",
            "gene_name": "PPP2R5A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O14818-1",
            "protein_name": "Proteasome subunit alpha type-7",
            "gene_name": "PSMA7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P35222-1",
            "protein_name": "Catenin beta-1",
            "gene_name": "CTNNB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y297-1",
            "protein_name": "F-box/WD repeat-containing protein 1A",
            "gene_name": "BTRC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O15169-1",
            "protein_name": "Axin-1",
            "gene_name": "AXIN1",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P49720",
                    "url": "https://www.uniprot.org/uniprot/P49720"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10092233",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 69
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}