{
    "title": "Adenylyl cyclase activation modulates activity-dependent changes in synaptic strength and Ca2+/calmodulin-dependent kinase II autophosphorylation.",
    "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience",
    "date": "1999",
    "authors": "Makhinson M, Chotiner JK, Watson JB, O'Dell TJ",
    "reference": {
        "type": "PubMed",
        "id": "10087064",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10087064"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P11798-1",
            "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit alpha",
            "gene_name": "Camk2a",
            "tax_name": "Mouse"
        }
    ],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P11798",
                    "url": "https://www.uniprot.org/uniprot/P11798"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 286,
            "end_pos": 286,
            "kinase_uniprot_canonical_ac": "P11798-1",
            "kinase_gene_name": "Camk2a",
            "residue": "Thr",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P11798",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11798"
                },
                {
                    "database": "PubMed",
                    "id": "10087064",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10087064"
                },
                {
                    "database": "PubMed",
                    "id": "12379661",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/12379661"
                },
                {
                    "database": "PubMed",
                    "id": "23516528",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/23516528"
                },
                {
                    "database": "UniProtKB",
                    "id": "P11798",
                    "url": "https://www.uniprot.org/uniprot/P11798"
                },
                {
                    "database": "PubMed",
                    "id": "28130356",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/28130356"
                }
            ],
            "site_lbl": "Thr286",
            "uniprot_canonical_ac": "P11798-1"
        },
        {
            "start_pos": 286,
            "end_pos": 286,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "Phosphothreonine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P11798",
                    "url": "https://www.uniprot.org/uniprot/P11798"
                },
                {
                    "database": "phospho.ELM",
                    "id": "P11798",
                    "url": "http://phospho.elm.eu.org/byAccession/P11798.html"
                },
                {
                    "database": "iPTMnet",
                    "id": "P11798",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11798"
                },
                {
                    "database": "PubMed",
                    "id": "17114649",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/17114649"
                },
                {
                    "database": "PubMed",
                    "id": "10087064",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10087064"
                },
                {
                    "database": "PubMed",
                    "id": "15140879",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/15140879"
                },
                {
                    "database": "PubMed",
                    "id": "19257910",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/19257910"
                },
                {
                    "database": "PubMed",
                    "id": "24349346",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/24349346"
                },
                {
                    "database": "PubMed",
                    "id": "24374198",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/24374198"
                }
            ],
            "site_lbl": "Thr286",
            "uniprot_canonical_ac": "P11798-1"
        }
    ],
    "record_id": "pubmed.10087064",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 2
                },
                {
                    "field": "total_sites",
                    "count": 1
                }
            ],
            "sort_fields": [
                "start_pos",
                "end_pos",
                "kinase_uniprot_canonical_ac",
                "kinase_gene_name",
                "residue",
                "comment",
                "site_lbl",
                "uniprot_canonical_ac"
            ]
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}
