{
    "title": "Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors.",
    "journal": "Blood",
    "date": "1999",
    "authors": "Nishida K, Yoshida Y, Itoh M, Fukada T, Ohtani T, Shirogane T, Atsumi T, Takahashi-Tezuka M, Ishihara K, Hibi M, Hirano T",
    "reference": {
        "type": "PubMed",
        "id": "10068651",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10068651"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P04211-1",
            "protein_name": "Immunoglobulin lambda variable 7-43",
            "gene_name": "IGLV7-43",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O15530-1",
            "protein_name": "3-phosphoinositide-dependent protein kinase 1",
            "gene_name": "PDPK1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06315-1",
            "protein_name": "Immunoglobulin kappa variable 5-2",
            "gene_name": "IGKV5-2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01721-1",
            "protein_name": "Immunoglobulin lambda variable 6-57",
            "gene_name": "IGLV6-57",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P12319-1",
            "protein_name": "High affinity immunoglobulin epsilon receptor subunit alpha",
            "gene_name": "FCER1A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A0A075B6S6-1",
            "protein_name": "Immunoglobulin kappa variable 2D-30",
            "gene_name": "IGKV2D-30",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01780-1",
            "protein_name": "Immunoglobulin heavy variable 3-7",
            "gene_name": "IGHV3-7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00459-1",
            "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta",
            "gene_name": "PIK3R2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01700-1",
            "protein_name": "Immunoglobulin lambda variable 1-47",
            "gene_name": "IGLV1-47",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01593-1",
            "protein_name": "Immunoglobulin kappa variable 1D-33",
            "gene_name": "IGKV1D-33",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01763-1",
            "protein_name": "Immunoglobulin heavy variable 3-48",
            "gene_name": "IGHV3-48",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A2NJV5-1",
            "protein_name": "Immunoglobulin kappa variable 2-29",
            "gene_name": "IGKV2-29",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P80748-1",
            "protein_name": "Immunoglobulin lambda variable 3-21",
            "gene_name": "IGLV3-21",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q60631-1",
            "protein_name": "Growth factor receptor-bound protein 2",
            "gene_name": "Grb2",
            "tax_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P01714-1",
            "protein_name": "Immunoglobulin lambda variable 3-19",
            "gene_name": "IGLV3-19",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01814-1",
            "protein_name": "Immunoglobulin heavy variable 2-70",
            "gene_name": "IGHV2-70",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01742-1",
            "protein_name": "Immunoglobulin heavy variable 1-69",
            "gene_name": "IGHV1-69",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01782-1",
            "protein_name": "Immunoglobulin heavy variable 3-9",
            "gene_name": "IGHV3-9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01825-1",
            "protein_name": "Immunoglobulin heavy variable 4-59",
            "gene_name": "IGHV4-59",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01768-1",
            "protein_name": "Immunoglobulin heavy variable 3-30",
            "gene_name": "IGHV3-30",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A0A075B6P5-1",
            "protein_name": "Immunoglobulin kappa variable 2-28",
            "gene_name": "IGKV2-28",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04432-1",
            "protein_name": "Immunoglobulin kappa variable 1D-39",
            "gene_name": "IGKV1D-39",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01704-1",
            "protein_name": "Immunoglobulin lambda variable 2-14",
            "gene_name": "IGLV2-14",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01709-1",
            "protein_name": "Immunoglobulin lambda variable 2-8",
            "gene_name": "IGLV2-8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P27986-1",
            "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha",
            "gene_name": "PIK3R1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01767-1",
            "protein_name": "Immunoglobulin heavy variable 3-53",
            "gene_name": "IGHV3-53",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01614-1",
            "protein_name": "Immunoglobulin kappa variable 2D-40",
            "gene_name": "IGKV2D-40",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UQC2-1",
            "protein_name": "GRB2-associated-binding protein 2",
            "gene_name": "GAB2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01699-1",
            "protein_name": "Immunoglobulin lambda variable 1-44",
            "gene_name": "IGLV1-44",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01602-1",
            "protein_name": "Immunoglobulin kappa variable 1-5",
            "gene_name": "IGKV1-5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0DOY3-1",
            "protein_name": "Immunoglobulin lambda constant 3",
            "gene_name": "IGLC3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04430-1",
            "protein_name": "Immunoglobulin kappa variable 1-16",
            "gene_name": "IGKV1-16",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01597-1",
            "protein_name": "Immunoglobulin kappa variable 1-39",
            "gene_name": "IGKV1-39",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01619-1",
            "protein_name": "Immunoglobulin kappa variable 3-20",
            "gene_name": "IGKV3-20",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30273-1",
            "protein_name": "High affinity immunoglobulin epsilon receptor subunit gamma",
            "gene_name": "FCER1G",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01706-1",
            "protein_name": "Immunoglobulin lambda variable 2-11",
            "gene_name": "IGLV2-11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06241-1",
            "protein_name": "Tyrosine-protein kinase Fyn",
            "gene_name": "FYN",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CF74-1",
            "protein_name": "Immunoglobulin lambda constant 6",
            "gene_name": "IGLC6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P42338-1",
            "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform",
            "gene_name": "PIK3CB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG04-1",
            "protein_name": "Immunoglobulin lambda constant 1",
            "gene_name": "IGLC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01705-1",
            "protein_name": "Immunoglobulin lambda variable 2-23",
            "gene_name": "IGLV2-23",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P35235-2",
            "protein_name": "Tyrosine-protein phosphatase non-receptor type 11",
            "gene_name": "Ptpn11",
            "tax_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P06331-1",
            "protein_name": "Immunoglobulin heavy variable 4-34",
            "gene_name": "IGHV4-34",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P42336-1",
            "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform",
            "gene_name": "PIK3CA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01601-1",
            "protein_name": "Immunoglobulin kappa variable 1D-16",
            "gene_name": "IGKV1D-16",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01772-1",
            "protein_name": "Immunoglobulin heavy variable 3-33",
            "gene_name": "IGHV3-33",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01854-2",
            "protein_name": "Immunoglobulin heavy constant epsilon",
            "gene_name": "IGHE",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P23083-1",
            "protein_name": "Immunoglobulin heavy variable 1-2",
            "gene_name": "IGHV1-2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04433-1",
            "protein_name": "Immunoglobulin kappa variable 3-11",
            "gene_name": "IGKV3-11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01594-1",
            "protein_name": "Immunoglobulin kappa variable 1-33",
            "gene_name": "IGKV1-33",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06310-1",
            "protein_name": "Immunoglobulin kappa variable 2-30",
            "gene_name": "IGKV2-30",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01764-1",
            "protein_name": "Immunoglobulin heavy variable 3-23",
            "gene_name": "IGHV3-23",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01824-1",
            "protein_name": "Immunoglobulin heavy variable 4-39",
            "gene_name": "IGHV4-39",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01599-1",
            "protein_name": "Immunoglobulin kappa variable 1-17",
            "gene_name": "IGKV1-17",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q06124-2",
            "protein_name": "Tyrosine-protein phosphatase non-receptor type 11",
            "gene_name": "PTPN11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9GZY6-1",
            "protein_name": "Linker for activation of T-cells family member 2",
            "gene_name": "LAT2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0DOY2-1",
            "protein_name": "Immunoglobulin lambda constant 2",
            "gene_name": "IGLC2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A0M8Q6-1",
            "protein_name": "Immunoglobulin lambda constant 7",
            "gene_name": "IGLC7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q07889-1",
            "protein_name": "Son of sevenless homolog 1",
            "gene_name": "SOS1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01766-1",
            "protein_name": "Immunoglobulin heavy variable 3-13",
            "gene_name": "IGHV3-13",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06312-1",
            "protein_name": "Immunoglobulin kappa variable 4-1",
            "gene_name": "IGKV4-1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01615-1",
            "protein_name": "Immunoglobulin kappa variable 2D-28",
            "gene_name": "IGKV2D-28",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01701-1",
            "protein_name": "Immunoglobulin lambda variable 1-51",
            "gene_name": "IGLV1-51",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01624-1",
            "protein_name": "Immunoglobulin kappa variable 3-15",
            "gene_name": "IGKV3-15",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01817-1",
            "protein_name": "Immunoglobulin heavy variable 2-5",
            "gene_name": "IGHV2-5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01717-1",
            "protein_name": "Immunoglobulin lambda variable 3-25",
            "gene_name": "IGLV3-25",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Z1S8-1",
            "protein_name": "GRB2-associated-binding protein 2",
            "gene_name": "Gab2",
            "tax_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P01703-1",
            "protein_name": "Immunoglobulin lambda variable 1-40",
            "gene_name": "IGLV1-40",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01743-1",
            "protein_name": "Immunoglobulin heavy variable 1-46",
            "gene_name": "IGHV1-46",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P07948-1",
            "protein_name": "Tyrosine-protein kinase Lyn",
            "gene_name": "LYN",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01718-1",
            "protein_name": "Immunoglobulin lambda variable 3-27",
            "gene_name": "IGLV3-27",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01715-1",
            "protein_name": "Immunoglobulin lambda variable 3-1",
            "gene_name": "IGLV3-1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01611-1",
            "protein_name": "Immunoglobulin kappa variable 1D-12",
            "gene_name": "IGKV1D-12",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q01362-1",
            "protein_name": "High affinity immunoglobulin epsilon receptor subunit beta",
            "gene_name": "MS4A2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01762-1",
            "protein_name": "Immunoglobulin heavy variable 3-11",
            "gene_name": "IGHV3-11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A0A0C4DH73-1",
            "protein_name": "Immunoglobulin kappa variable 1-12",
            "gene_name": "IGKV1-12",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A0A0C4DH25-1",
            "protein_name": "Immunoglobulin kappa variable 3D-20",
            "gene_name": "IGKV3D-20",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P43405-1",
            "protein_name": "Tyrosine-protein kinase SYK",
            "gene_name": "SYK",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01834-1",
            "protein_name": "Immunoglobulin kappa constant",
            "gene_name": "IGKC",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P04211",
                    "url": "https://www.uniprot.org/uniprot/P04211"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10068651",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 79
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}
