{
    "title": "IkappaBalpha ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, betaTrCP1 and betaTrCP2.",
    "journal": "Biochemical and biophysical research communications",
    "date": "1999",
    "authors": "Suzuki H, Chiba T, Kobayashi M, Takeuchi M, Suzuki T, Ichiyama A, Ikenoue T, Omata M, Furuichi K, Tanaka K",
    "reference": {
        "type": "PubMed",
        "id": "10066435",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10066435"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q04206-1",
            "protein_name": "Transcription factor p65",
            "gene_name": "RELA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49720-1",
            "protein_name": "Proteasome subunit beta type-3",
            "gene_name": "PSMB3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P61289-1",
            "protein_name": "Proteasome activator complex subunit 3",
            "gene_name": "PSME3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "A5LHX3-1",
            "protein_name": "Proteasome subunit beta type-11",
            "gene_name": "PSMB11",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q06323-1",
            "protein_name": "Proteasome activator complex subunit 1",
            "gene_name": "PSME1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00233-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 9",
            "gene_name": "PSMD9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25963-1",
            "protein_name": "NF-kappa-B inhibitor alpha",
            "gene_name": "NFKBIA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62191-1",
            "protein_name": "26S proteasome regulatory subunit 4",
            "gene_name": "PSMC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P25786-1",
            "protein_name": "Proteasome subunit alpha type-1",
            "gene_name": "PSMA1",
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        },
        {
            "uniprot_canonical_ac": "Q9UKB1-1",
            "protein_name": "F-box/WD repeat-containing protein 11",
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            "tax_name": "Human"
        },
        {
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            "protein_name": "26S proteasome regulatory subunit 7",
            "gene_name": "PSMC2",
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        },
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        },
        {
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        },
        {
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            "protein_name": "Proteasome subunit beta type-10",
            "gene_name": "PSMB10",
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        },
        {
            "uniprot_canonical_ac": "Q16401-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 5",
            "gene_name": "PSMD5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62987-1",
            "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
            "gene_name": "UBA52",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y6K9-1",
            "protein_name": "NF-kappa-B essential modulator",
            "gene_name": "IKBKG",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P05771-1",
            "protein_name": "Protein kinase C beta type",
            "gene_name": "PRKCB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6ZVN7-1",
            "protein_name": "Putative protein SEM1, isoform 2",
            "gene_name": "SEM1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG48-1",
            "protein_name": "Polyubiquitin-C",
            "gene_name": "UBC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62333-1",
            "protein_name": "26S proteasome regulatory subunit 10B",
            "gene_name": "PSMC6",
            "tax_name": "Human"
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        {
            "uniprot_canonical_ac": "P62195-1",
            "protein_name": "26S proteasome regulatory subunit 8",
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00221-1",
            "protein_name": "NF-kappa-B inhibitor epsilon",
            "gene_name": "NFKBIE",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75832-1",
            "protein_name": "26S proteasome non-ATPase regulatory subunit 10",
            "gene_name": "PSMD10",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UL46-1",
            "protein_name": "Proteasome activator complex subunit 2",
            "gene_name": "PSME2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13616-1",
            "protein_name": "Cullin-1",
            "gene_name": "CUL1",
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        },
        {
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            "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
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        },
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        },
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        },
        {
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            "tax_name": "Human"
        },
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            "protein_name": "Polyubiquitin-B",
            "gene_name": "UBB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14997-1",
            "protein_name": "Proteasome activator complex subunit 4",
            "gene_name": "PSME4",
            "tax_name": "Human"
        },
        {
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            "gene_name": "PSMF1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9BXL7-1",
            "protein_name": "Caspase recruitment domain-containing protein 11",
            "gene_name": "CARD11",
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        },
        {
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            "tax_name": "Human"
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        {
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            "protein_name": "Nuclear factor NF-kappa-B p105 subunit",
            "gene_name": "NFKB1",
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        },
        {
            "uniprot_canonical_ac": "P17980-1",
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        },
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        },
        {
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O14920-1",
            "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta",
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        },
        {
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            "protein_name": "26S proteasome regulatory subunit 6B",
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        },
        {
            "uniprot_canonical_ac": "P55036-1",
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            "tax_name": "Human"
        },
        {
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        },
        {
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            "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
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        },
        {
            "uniprot_canonical_ac": "Q15008-1",
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            "gene_name": "PSMD6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P63208-1",
            "protein_name": "S-phase kinase-associated protein 1",
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            "tax_name": "Human"
        },
        {
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            "protein_name": "NF-kappa-B inhibitor beta",
            "gene_name": "NFKBIB",
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        },
        {
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        {
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        {
            "uniprot_canonical_ac": "Q9UDY8-1",
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        {
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        {
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        },
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        },
        {
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        {
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        },
        {
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        },
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            "uniprot_canonical_ac": "O14818-1",
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        },
        {
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            "protein_name": "F-box/WD repeat-containing protein 1A",
            "gene_name": "BTRC",
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        }
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        {
            "name": "Homo sapiens",
            "taxid": 9606,
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                    "database": "UniProtKB",
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            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10066435",
    "abstract": "",
    "glycosylation": [],
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