{
    "title": "Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly.",
    "journal": "Proceedings of the National Academy of Sciences of the United States of America",
    "date": "1999",
    "authors": "Matsuzono Y, Kinoshita N, Tamura S, Shimozawa N, Hamasaki M, Ghaedi K, Wanders RJ, Suzuki Y, Kondo N, Fujiki Y",
    "reference": {
        "type": "PubMed",
        "id": "10051604",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10051604"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P40855-1",
            "protein_name": "Peroxisomal biogenesis factor 19",
            "gene_name": "PEX19",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P40855",
                    "url": "https://www.uniprot.org/uniprot/P40855"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "mutagenesis": [
        {
            "start_pos": 296,
            "end_pos": 296,
            "sequence_org": "C",
            "sequence_mut": "A",
            "comment": "Slightly inhibits PEX19 function on peroxisome biogenesis.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P40855",
                    "url": "https://www.uniprot.org/uniprot/P40855"
                },
                {
                    "database": "PubMed",
                    "id": "9339377",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/9339377"
                },
                {
                    "database": "PubMed",
                    "id": "10777694",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10777694"
                },
                {
                    "database": "PubMed",
                    "id": "10051604",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10051604"
                },
                {
                    "database": "PubMed",
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                    "url": "https://pubmed.ncbi.nlm.nih.gov/10704444"
                }
            ],
            "uniprot_canonical_ac": "P40855-1"
        },
        {
            "start_pos": 296,
            "end_pos": 296,
            "sequence_org": "C",
            "sequence_mut": "S",
            "comment": "Abolishes farnesylation. Abolishes PEX19 function on peroxisome biogenesis. Does not affect binding to ABCD1, ABCD2 and ABCD3.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P40855",
                    "url": "https://www.uniprot.org/uniprot/P40855"
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                },
                {
                    "database": "PubMed",
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                },
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                }
            ],
            "uniprot_canonical_ac": "P40855-1"
        }
    ],
    "record_id": "pubmed.10051604",
    "abstract": "",
    "glycosylation": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
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        {
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