{
    "title": "Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta.",
    "journal": "Molecular and cellular biology",
    "date": "1999",
    "authors": "Wong C, Rougier-Chapman EM, Frederick JP, Datto MB, Liberati NT, Li JM, Wang XF",
    "reference": {
        "type": "PubMed",
        "id": "10022869",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10022869"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q15796-1",
            "protein_name": "Mothers against decapentaplegic homolog 2",
            "gene_name": "SMAD2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75909-3",
            "protein_name": "Cyclin-K",
            "gene_name": "CCNK",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P50750-1",
            "protein_name": "Cyclin-dependent kinase 9",
            "gene_name": "CDK9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00255-2",
            "protein_name": "Menin",
            "gene_name": "MEN1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P08123-1",
            "protein_name": "Collagen alpha-2(I) chain",
            "gene_name": "COL1A2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14186-1",
            "protein_name": "Transcription factor Dp-1",
            "gene_name": "TFDP1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P42772-1",
            "protein_name": "Cyclin-dependent kinase 4 inhibitor B",
            "gene_name": "CDKN2B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13547-1",
            "protein_name": "Histone deacetylase 1",
            "gene_name": "HDAC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62987-1",
            "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
            "gene_name": "UBA52",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O60583-1",
            "protein_name": "Cyclin-T2",
            "gene_name": "CCNT2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P84022-1",
            "protein_name": "Mothers against decapentaplegic homolog 3",
            "gene_name": "SMAD3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P24863-1",
            "protein_name": "Cyclin-C",
            "gene_name": "CCNC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG48-1",
            "protein_name": "Polyubiquitin-C",
            "gene_name": "UBC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P05121-1",
            "protein_name": "Plasminogen activator inhibitor 1",
            "gene_name": "SERPINE1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28749-1",
            "protein_name": "Retinoblastoma-like protein 1",
            "gene_name": "RBL1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15583-1",
            "protein_name": "Homeobox protein TGIF1",
            "gene_name": "TGIF1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13485-1",
            "protein_name": "Mothers against decapentaplegic homolog 4",
            "gene_name": "SMAD4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15329-1",
            "protein_name": "Transcription factor E2F5",
            "gene_name": "E2F5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9GZN2-1",
            "protein_name": "Homeobox protein TGIF2",
            "gene_name": "TGIF2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62979-1",
            "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
            "gene_name": "RPS27A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6ZNA4-1",
            "protein_name": "E3 ubiquitin-protein ligase Arkadia",
            "gene_name": "RNF111",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P17275-1",
            "protein_name": "Transcription factor JunB",
            "gene_name": "JUNB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG47-1",
            "protein_name": "Polyubiquitin-B",
            "gene_name": "UBB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O60563-1",
            "protein_name": "Cyclin-T1",
            "gene_name": "CCNT1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P01106-2",
            "protein_name": "Myc proto-oncogene protein",
            "gene_name": "MYC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P27361-1",
            "protein_name": "Mitogen-activated protein kinase 3",
            "gene_name": "MAPK3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P67809-1",
            "protein_name": "Y-box-binding protein 1",
            "gene_name": "YBX1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16254-1",
            "protein_name": "Transcription factor E2F4",
            "gene_name": "E2F4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P08047-1",
            "protein_name": "Transcription factor Sp1",
            "gene_name": "SP1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28482-1",
            "protein_name": "Mitogen-activated protein kinase 1",
            "gene_name": "MAPK1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49336-1",
            "protein_name": "Cyclin-dependent kinase 8",
            "gene_name": "CDK8",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14188-1",
            "protein_name": "Transcription factor Dp-2",
            "gene_name": "TFDP2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9GZV5-1",
            "protein_name": "WW domain-containing transcription regulator protein 1",
            "gene_name": "WWTR1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O15105-1",
            "protein_name": "Mothers against decapentaplegic homolog 7",
            "gene_name": "SMAD7",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q09472-1",
            "protein_name": "Histone acetyltransferase p300",
            "gene_name": "EP300",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P09958-1",
            "protein_name": "Furin",
            "gene_name": "FURIN",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q15796",
                    "url": "https://www.uniprot.org/uniprot/Q15796"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10022869",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 36
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}