{ "uniprot_canonical_ac": "A0A1L4FML6-1", "uniprot_ac": "A0A1L4FML6", "uniprot_id": "A0A1L4FML6_CHICK", "mass": { "chemical_mass": 122295.0, "monoisotopic_mass": 122295.0 }, "refseq": { "ac": "NP_001011688", "name": "toll-like receptor 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688" }, "gene_names": [ { "name": "TLR7", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6", "id": "A0A1L4FML6" }, { "name": "TLR7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688", "id": "NP_001011688" } ], "protein_names": [ { "name": "Toll-like receptor 7", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1L4FML6/entry#names_and_taxonomy", "id": "A0A1L4FML6" }, { "name": "toll-like receptor 7-long", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688", "id": "NP_001011688" }, { "name": "toll-like receptor 7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688", "id": "NP_001011688" } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720504.1, KM486607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000024.1, AJ740367.1, KM486601.1, KM486600.1 and AJ720504.1. On Nov 24, 2021 this sequence version replaced NP_001011688.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001011688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688" } ] }, { "annotation": "Antiviral response elicited against avian influenza virus infection following activation of TLR7 signaling pathway is attributable to interleukin IL-1beta production. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001011688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688" }, { "database": "PubMed", "id": "30514372", "url": "https://glygen.org/publication/PubMed/30514372" } ] }, { "annotation": "Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway.", "evidence": [ { "database": "RefSeq", "id": "NP_001011688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688" }, { "database": "PubMed", "id": "32524263", "url": "https://glygen.org/publication/PubMed/32524263" } ] }, { "annotation": "Results showed that activation of TLR7 is associated with anorexia, hypoactivity, hypothermia, disturbance of feed passage in the digestive tract and the response to stress in chicks", "evidence": [ { "database": "RefSeq", "id": "NP_001011688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688" }, { "database": "PubMed", "id": "31973574", "url": "https://glygen.org/publication/PubMed/31973574" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TLR7", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6", "locus": { "chromosome": "1", "start_pos": 123560512, "end_pos": 123568139, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001897", "url": "https://www.ensembl.org/id/ENSGALG00010001897" } ] } } ], "crossref": [ { "id": "418638", "url": "https://www.ncbi.nlm.nih.gov/gene/418638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418638", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418638", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNSKYLR", "url": "https://omabrowser.org/oma/group/CNSKYLR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L4FML6", "url": "https://www.orthodb.org/?gene=A0A1L4FML6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47410", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47410", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47410:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47410:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF18837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18837", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001011688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L4FML6-1", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X410", "url": "https://www.uniprot.org/uniprot/A0A8V0X410", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X410-1", "url": "https://www.uniprot.org/uniprot/A0A8V0X410-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDF0", "url": "https://www.uniprot.org/uniprot/A0A8V0XDF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDF0-1", "url": "https://www.uniprot.org/uniprot/A0A8V0XDF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDV1", "url": "https://www.uniprot.org/uniprot/A0A8V0XDV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDV1-1", "url": "https://www.uniprot.org/uniprot/A0A8V0XDV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNLSEVAAHRKMVHHARTSNALLFVLLFLFPMLLSGRWFPKTLPCDVEAFESTVRVDCSDRRLKEVPRGIPGNATNLTLTINHIPRISPASFTQLENLVEIDFRCNCVPPRLGPKDNVCITPPSIENGSFAALSRLKSLYLDANQLSKIPRGLPATLRLLSLEANNIFSIKKNTFSELRNIELLYLGQNCYYRNPCNVSFEIEETAFLNLKNLTVLSLKSNNLTFIPPNLSSTLKELYIYNNRIQEVQEHDLSNLYNLEILDLSGNCPRCYNAPYPCTPCPNISIKIHSKAFYSLKKLRILRLHSNSLQSIPSSWFKNIKNLKNLDLSQNFLIKEIGDAEFLKLIPSLVELDLSFNFELQMYSPFLNLSKTFSCLSNLETLRIKGYVFKELREENLDPLLNLRNLTVLDLGTNFIKIADLRVFKKFRSLKIIDLSMNKISPSSGESNFYGFCSDHRITVEQYSRHVLQEMHYFRYDEYGRSCKSKDKEADSYQPLVNGDCMSYGETLDLSRNNIFFVNSIDFQDLSFLKCLNLSGNAISQTLNGSEFYYLSGLKYLDFSNNRIDLLYSTAFKELKFLEILDLSNNKHYFLAEGVSHVLSFMKNLAYLKKLMMNENEISTSISTGMESQSLQTLEFRGNRLDIFWSDGKKEYLSFFKNLTNLEQLDISSNMLNFLPPDVFEAMPPELKILNLTSNRLHTFNWGKLHLLTKLITLDLSNNLLTTVPRKLSNCTSTLQELILRNNRITRITKYFLRGAIQLTYLDLSSNKIQIIKKSSFPENIINNLRMLLLHNNPFKCNCDAVWFVGWINQTQVAIPLLATDVTCAGPGAHKGRSLVFLDLNTCELDTSYFIMYALSTSAVLCLMMFAVMSHLYFWDVWYSYHYCTAKLKGYRRIPLPDACYDAFIAYDNTDLAVNEWVMTELVEKLEDQKARQFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYIKSGTFKTTFYMAHQRLLDEKIDVIILIFLEKVLQKSRYVQLRKRLCRSSVLEWPTNPRSQPYFWQRLKNAIAMNNTLSYNKLLQETV", "length": 1059, "header": "tr|A0A1L4FML6-1|A0A1L4FML6_CHICK Isoform 1 of Toll-like receptor 7 OS=Gallus gallus OX=9031 GN=TLR7 PE=3 SV=1 CANONICAL=A0A1L4FML6-1" }, "isoforms": [ { "isoform_ac": "A0A1L4FML6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L4FML6/entry#A0A1L4FML6-1", "sequence": { "sequence": "MTNLSEVAAHRKMVHHARTSNALLFVLLFLFPMLLSGRWFPKTLPCDVEAFESTVRVDCSDRRLKEVPRGIPGNATNLTLTINHIPRISPASFTQLENLVEIDFRCNCVPPRLGPKDNVCITPPSIENGSFAALSRLKSLYLDANQLSKIPRGLPATLRLLSLEANNIFSIKKNTFSELRNIELLYLGQNCYYRNPCNVSFEIEETAFLNLKNLTVLSLKSNNLTFIPPNLSSTLKELYIYNNRIQEVQEHDLSNLYNLEILDLSGNCPRCYNAPYPCTPCPNISIKIHSKAFYSLKKLRILRLHSNSLQSIPSSWFKNIKNLKNLDLSQNFLIKEIGDAEFLKLIPSLVELDLSFNFELQMYSPFLNLSKTFSCLSNLETLRIKGYVFKELREENLDPLLNLRNLTVLDLGTNFIKIADLRVFKKFRSLKIIDLSMNKISPSSGESNFYGFCSDHRITVEQYSRHVLQEMHYFRYDEYGRSCKSKDKEADSYQPLVNGDCMSYGETLDLSRNNIFFVNSIDFQDLSFLKCLNLSGNAISQTLNGSEFYYLSGLKYLDFSNNRIDLLYSTAFKELKFLEILDLSNNKHYFLAEGVSHVLSFMKNLAYLKKLMMNENEISTSISTGMESQSLQTLEFRGNRLDIFWSDGKKEYLSFFKNLTNLEQLDISSNMLNFLPPDVFEAMPPELKILNLTSNRLHTFNWGKLHLLTKLITLDLSNNLLTTVPRKLSNCTSTLQELILRNNRITRITKYFLRGAIQLTYLDLSSNKIQIIKKSSFPENIINNLRMLLLHNNPFKCNCDAVWFVGWINQTQVAIPLLATDVTCAGPGAHKGRSLVFLDLNTCELDTSYFIMYALSTSAVLCLMMFAVMSHLYFWDVWYSYHYCTAKLKGYRRIPLPDACYDAFIAYDNTDLAVNEWVMTELVEKLEDQKARQFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYIKSGTFKTTFYMAHQRLLDEKIDVIILIFLEKVLQKSRYVQLRKRLCRSSVLEWPTNPRSQPYFWQRLKNAIAMNNTLSYNKLLQETV", "length": 1059, "header": "tr|A0A1L4FML6-1|A0A1L4FML6_CHICK Isoform 1 of Toll-like receptor 7 OS=Gallus gallus OX=9031 GN=TLR7 PE=3 SV=1 CANONICAL=A0A1L4FML6-1" }, "locus": { "chromosome": "1", "start_pos": 123567980, "end_pos": 123561516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004337.1", "url": "https://www.ensembl.org/id/ENSGALT00010004337.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002615.1", "url": "https://www.ensembl.org/id/ENSGALP00010002615.1" } ] } }, { "isoform_ac": "A0A8V0X410-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L4FML6/entry#A0A8V0X410-1", "sequence": { "sequence": "MLLSGRWFPKTLPCDVEAFESTVRVDCSDRRLKEVPRGIPGNATNLTLTINHIPRISPASFTQLENLVEIDFRCNCVPPRLGPKDNVCITPPSIENGSFAALSRLKSLYLDANQLSKIPRGLPATLRLLSLEANNIFSIKKNTFSELRNIELLYLGQNCYYRNPCNVSFEIEETAFLNLKNLTVLSLKSNNLTFIPPNLSSTLKELYIYNNRIQEVQEHDLSNLYNLEILDLSGNCPRCYNAPYPCTPCPNISIKIHSKAFYSLKKLRILRLHSNSLQSIPSSWFKNIKNLKNLDLSQNFLIKEIGDAEFLKLIPSLVELDLSFNFELQMYSPFLNLSKTFSCLSNLETLRIKGYVFKELREENLDPLLNLRNLTVLDLGTNFIKIADLRVFKKFRSLKIIDLSMNKISPSSGESNFYGFCSDHRITVEQYSRHVLQEMHYFRYDEYGRSCKSKDKEADSYQPLVNGDCMSYGETLDLSRNNIFFVNSIDFQDLSFLKCLNLSGNAISQTLNGSEFYYLSGLKYLDFSNNRIDLLYSTAFKELKFLEILDLSNNKHYFLAEGVSHVLSFMKNLAYLKKLMMNENEISTSISTGMESQSLQTLEFRGNRLDIFWSDGKKEYLSFFKNLTNLEQLDISSNMLNFLPPDVFEAMPPELKILNLTSNRLHTFNWGKLHLLTKLITLDLSNNLLTTVPRKLSNCTSTLQELILRNNRITRITKYFLRGAIQLTYLDLSSNKIQIIKKSSFPENIINNLRMLLLHNNPFKCNCDAVWFVGWINQTQVAIPLLATDVTCAGPGAHKGRSLVFLDLNTCELDTSYFIMYALSTSAVLCLMMFAVMSHLYFWDVWYSYHYCTAKLKGYRRIPLPDACYDAFIAYDNTDLAVNEWVMTELVEKLEDQKARQFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYIKSGTFKTTFYMAHQRLLDEKIDVIILIFLEKVLQKSRYVQLRKRLCRSSVLEWPTNPRSQPYFWQRLKNAIAMNNTLSYNKLLQETV", "length": 1027, "header": "tr|A0A8V0X410-1|A0A1L4FML6_CHICK Computationally mapped isoform of Toll-like receptor 7 OS=Gallus gallus OX=9031 GN=TLR7 PE=3 SV=1 CANONICAL=A0A1L4FML6-1" }, "locus": { "chromosome": "1", "start_pos": 123564596, "end_pos": 123561516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004331.1", "url": "https://www.ensembl.org/id/ENSGALT00010004331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002609.1", "url": "https://www.ensembl.org/id/ENSGALP00010002609.1" } ] } }, { "isoform_ac": "A0A8V0XDF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L4FML6/entry#A0A8V0XDF0-1", "sequence": { "sequence": "MPGFLKIQKQVHHARTSNALLFVLLFLFPMLLSGRWFPKTLPCDVEAFESTVRVDCSDRRLKEVPRGIPGNATNLTLTINHIPRISPASFTQLENLVEIDFRCNCVPPRLGPKDNVCITPPSIENGSFAALSRLKSLYLDANQLSKIPRGLPATLRLLSLEANNIFSIKKNTFSELRNIELLYLGQNCYYRNPCNVSFEIEETAFLNLKNLTVLSLKSNNLTFIPPNLSSTLKELYIYNNRIQEVQEHDLSNLYNLEILDLSGNCPRCYNAPYPCTPCPNISIKIHSKAFYSLKKLRILRLHSNSLQSIPSSWFKNIKNLKNLDLSQNFLIKEIGDAEFLKLIPSLVELDLSFNFELQMYSPFLNLSKTFSCLSNLETLRIKGYVFKELREENLDPLLNLRNLTVLDLGTNFIKIADLRVFKKFRSLKIIDLSMNKISPSSGESNFYGFCSDHRITVEQYSRHVLQEMHYFRYDEYGRSCKSKDKEADSYQPLVNGDCMSYGETLDLSRNNIFFVNSIDFQDLSFLKCLNLSGNAISQTLNGSEFYYLSGLKYLDFSNNRIDLLYSTAFKELKFLEILDLSNNKHYFLAEGVSHVLSFMKNLAYLKKLMMNENEISTSISTGMESQSLQTLEFRGNRLDIFWSDGKKEYLSFFKNLTNLEQLDISSNMLNFLPPDVFEAMPPELKILNLTSNRLHTFNWGKLHLLTKLITLDLSNNLLTTVPRKLSNCTSTLQELILRNNRITRITKYFLRGAIQLTYLDLSSNKIQIIKKSSFPENIINNLRMLLLHNNPFKCNCDAVWFVGWINQTQVAIPLLATDVTCAGPGAHKGRSLVFLDLNTCELDTSYFIMYALSTSAVLCLMMFAVMSHLYFWDVWYSYHYCTAKLKGYRRIPLPDACYDAFIAYDNTDLAVNEWVMTELVEKLEDQKARQFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYIKSGTFKTTFYMAHQRLLDEKIDVIILIFLEKVLQKSRYVQLRKRLCRSSVLEWPTNPRSQPYFWQRLKNAIAMNNTLSYNKLLQETV", "length": 1056, "header": "tr|A0A8V0XDF0-1|A0A1L4FML6_CHICK Computationally mapped isoform of Toll-like receptor 7 OS=Gallus gallus OX=9031 GN=TLR7 PE=3 SV=1 CANONICAL=A0A1L4FML6-1" }, "locus": { "chromosome": "1", "start_pos": 123567158, "end_pos": 123561516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004342.1", "url": "https://www.ensembl.org/id/ENSGALT00010004342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002620.1", "url": "https://www.ensembl.org/id/ENSGALP00010002620.1" } ] } }, { "isoform_ac": "A0A8V0XDV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L4FML6/entry#A0A8V0XDV1-1", "sequence": { "sequence": "MSSVWVHHARTSNALLFVLLFLFPMLLSGRWFPKTLPCDVEAFESTVRVDCSDRRLKEVPRGIPGNATNLTLTINHIPRISPASFTQLENLVEIDFRCNCVPPRLGPKDNVCITPPSIENGSFAALSRLKSLYLDANQLSKIPRGLPATLRLLSLEANNIFSIKKNTFSELRNIELLYLGQNCYYRNPCNVSFEIEETAFLNLKNLTVLSLKSNNLTFIPPNLSSTLKELYIYNNRIQEVQEHDLSNLYNLEILDLSGNCPRCYNAPYPCTPCPNISIKIHSKAFYSLKKLRILRLHSNSLQSIPSSWFKNIKNLKNLDLSQNFLIKEIGDAEFLKLIPSLVELDLSFNFELQMYSPFLNLSKTFSCLSNLETLRIKGYVFKELREENLDPLLNLRNLTVLDLGTNFIKIADLRVFKKFRSLKIIDLSMNKISPSSGESNFYGFCSDHRITVEQYSRHVLQEMHYFRYDEYGRSCKSKDKEADSYQPLVNGDCMSYGETLDLSRNNIFFVNSIDFQDLSFLKCLNLSGNAISQTLNGSEFYYLSGLKYLDFSNNRIDLLYSTAFKELKFLEILDLSNNKHYFLAEGVSHVLSFMKNLAYLKKLMMNENEISTSISTGMESQSLQTLEFRGNRLDIFWSDGKKEYLSFFKNLTNLEQLDISSNMLNFLPPDVFEAMPPELKILNLTSNRLHTFNWGKLHLLTKLITLDLSNNLLTTVPRKLSNCTSTLQELILRNNRITRITKYFLRGAIQLTYLDLSSNKIQIIKKSSFPENIINNLRMLLLHNNPFKCNCDAVWFVGWINQTQVAIPLLATDVTCAGPGAHKGRSLVFLDLNTCELDTSYFIMYALSTSAVLCLMMFAVMSHLYFWDVWYSYHYCTAKLKGYRRIPLPDACYDAFIAYDNTDLAVNEWVMTELVEKLEDQKARQFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYIKSGTFKTTFYMAHQRLLDEKIDVIILIFLEKVLQKSRYVQLRKRLCRSSVLEWPTNPRSQPYFWQRLKNAIAMNNTLSYNKLLQETV", "length": 1051, "header": "tr|A0A8V0XDV1-1|A0A1L4FML6_CHICK Computationally mapped isoform of Toll-like receptor 7 OS=Gallus gallus OX=9031 GN=TLR7 PE=3 SV=1 CANONICAL=A0A1L4FML6-1" }, "locus": { "chromosome": "1", "start_pos": 123566104, "end_pos": 123561516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004335.1", "url": "https://www.ensembl.org/id/ENSGALT00010004335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002613.1", "url": "https://www.ensembl.org/id/ENSGALP00010002613.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool": "isoglyp", "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "start_pos": 122, "start_aa": "T", "end_pos": 122, "end_aa": "T", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ], "filter_code": "00000000000000001000.00000000001000.1.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Antiviral response elicited against avian influenza virus infection following activation of toll-like receptor (TLR)7 signaling pathway is attributable to interleukin (IL)-1\u03b2 production.", "journal": "BMC research notes", "date": "2018-12-04", "authors": "Abdul-Cader Mohamed Sarjoon, De Silva Senapathi Upasama, Nagy Eva, Sharif Shayan, Abdul-Careem Mohamed Faizal", "evidence": [ { "database": "RefSeq", "id": "NP_001011688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688" } ], "reference": [ { "type": "PubMed", "id": "30514372", "url": "https://glygen.org/publication/PubMed/30514372" } ] }, { "title": "Effects of toll-like receptor-7 agonists on feeding behaviour, voluntary activity, cloacal temperature and crop emptying in chicks.", "journal": "British poultry science", "date": "2020-06", "authors": "Tachibana T, Takeda K, Khan M S I, Makino R, Cline M A", "evidence": [ { "database": "RefSeq", "id": "NP_001011688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688" } ], "reference": [ { "type": "PubMed", "id": "31973574", "url": "https://glygen.org/publication/PubMed/31973574" } ] }, { "title": "Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway.", "journal": "Archives of virology", "date": "2020-09", "authors": "Zhu Jinyan, Xu Shuang, Li Xueyan, Wang Jue, Jiang Yueqi, Hu Weichen, Ruan Wenke", "evidence": [ { "database": "RefSeq", "id": "NP_001011688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688" } ], "reference": [ { "type": "PubMed", "id": "32524263", "url": "https://glygen.org/publication/PubMed/32524263" } ] } ], "pathway": [ { "id": "gga:418638", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418638", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A288CG39-1", "protein_name": "Toll like receptor 7", "gene_name": "TLR7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPRKVFPVWTLKRQFLILFNIVLISELLGARWFPKTLPCDVSLDAPNAHVIVDCTDKHLTAIPGGIPTNATNLTLTINHIASITPASFQQLDHLVEIDFRCNCIPVRLGPKDNLCTRRLQIKPSSFSKLTYLKALYLDGNQLLEIPRDLPPSLQLLSLEANNIFWIMKENLTELANLEMLYLGQNCYYRNPCNVSFSIEKDAFLSLRNLKLLSLKDNNISAVPTVLPSTLTELFLYNNIIAKIQEDDFNNLSQLQVLDLSGNCPRCYNVPFPCTPCENNAPLQIHLHAFDALTELQVLRLHSNSLQYVPQRWFQNLNKLKELDLSQNFLAKEIGDAKFLHLLPNLVKLDLSFNYELQVYHTFMNLSDSFSSLKNLKVLRIKGYVFKELKSLNLSPLRNLPNLEVLDLGTNFIKIANLSIFKQFKTLKFIDLSVNKISPSGDSSESGFCSGMRTSAESHGPQVLESLHYFRYDEYARSCRFKNKEPSSSLPLNEDCSMYGQTLDLSRNNIFFIRSSEFQHLTFLKCLNLSGNSISQALNGSEFQPLVELKYLDFSNNRLDLLHSTAFEELRNLEVLDISSNSHYFQSEGITHMLDFTKNLKVLKKLMMNNNDIATSTSTTMESESLRILEFRGNHLDILWRDGDNRYLKFFKNLHKLEELDISENSLSFLPSGVFDGMPPNLKTLSLAKNGLKSFNWGKLQYLQNLETLDLSYNQLKTVPERLSNCSRSLKKLILKNNEIRNLTKYFLQDAFQLRHLDLSSNKIQVIQKTSFPENVLNNLQILFLHHNRFLCNCDAVWLVWWVNHTEVTIPFLATDVTCMGPGAHKGQSVVSLDLYTCELDLTNFVLFSLSLSAVLFLIVITIANHLYFWDVWYSYHFCKAKIKGYQRLISPNSCYDAFIVYDTKDPAVTEWVLDELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTEKFKIAFYLSHQRLMDEKVDVIILIFLEKPLQKSKFFQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVTYSQVFKETA", "length": 1054 }, "evidence": [ { "id": "A0A1L4FML6", "url": "https://omabrowser.org/oma/group/A0A1L4FML6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GHR4-1", "protein_name": "Toll-like receptor 7", "gene_name": "Tlr7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWTLKRQSFIFLNMILVSRVLGFRWYPKTLPCDVSLDSTNTHVIVDCTDKHLTEIPEGIPTNTTNLTLTINHIPSISPDSFHRLKHLEELDLRCNCVPILLGSKANVCTKRLQIRPGSFSGLSDLKSLYLDGNQLLEIPQDLPSSLQLLSLEANNIFSITKENLSELVNIESLYLGQNCYYRNPCNVSYSIEKDAFLVMKNLKVLSLKDNNVTAVPTILPPNLLELYLYNNIIKRIQEHDFNKLSQLQVLDLSGNCPRCYNVPYPCTPCENNSPLQIHDNAFDSLTELKVLRLHSNSLQHVPAEWFKNMSNLQELDLSQNYLAREIEEAKFLNSLPNLVQLDLSFNYELQVYHASITLPHSLSSLTKLKNLYIKGYVFKELKDSSLSVLHNLSNLEVLDLGTNFIKIADLNIFQQFENLKFIDLSVNKISPSEESREVGLCPNAQTSVDWHGPQVLEALHYFRYDEYARSCRFKNKEPPTFLPLNADCHTYGKTLDLSRNNIFFIKPSDFKHLSFLKCLNLSGNAIGQTLNGSELQPLRELRYLDFSNNRLDLLYSTAFEELQNLEILDLSSNSHYFQAEGITHMLNFTKKLRHLEKLMMNDNDISTSASRTMESESLRVLEFRGNHLDVLWRDGDNRYLDFFKNLLNLEELDISRNSLNSVPPGVFEGMPPNLTTLSLAKNGLRSFSWGRLQLLKHLKNLDLSHNQLTTVPARLANCSKSLTKLILNHNQIRQLTKYFLEDALQLRYLDISSNKIQVIQKTSFPENVLNNLNMLLLHHNRFLCNCDAVWFVWWVNHTDVTIPYLATDVTCAGPGAHKGQSVISLDLYTCELDLTNLILFSVSISSVLFLMIVMTTSHLFFWDMWYIYYFWKAKIKGYQHLQSMESCYDAFIVYDTKNSAVTEWVLQELVVKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSRKTVFVMTQKYAKTESFKMAFYLSHQRLMDEKVDVIILIFLEKPLQKSKFLQLRKRLCSSSVLEWPTNPQAHPYFWQCLKNALTTDNHVAYSQMFKETV", "length": 1046 }, "evidence": [ { "id": "A0A1L4FML6", "url": "https://omabrowser.org/oma/group/A0A1L4FML6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6QR22-1", "protein_name": "Toll like receptor 7", "gene_name": "TLR7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLKAKYVFPMWTLKRQFPILFNMILISGLLGARWFPKTLPCDVTLDAPNTHVIVDCTDKHLTEIPGGIPANATNLTLTINHIAGISPASFHRLDHLVEIDFRCNCVPVRLGPKDNVCTKRLQIKPNSFSKLTYLKSLYLDGNQLLEIPQDLPPSLQLLSLEANNIFLIMKENLTELANLEILYLGQNCYYRNPCNVSFTIEKDAFLNMRNLKLLSLKDNNISAVPTVLPSSLTELYLYNNIITKIQEDDFNNLSQLQVLDLSGNCPRCYNVPFPCTPCENNSPLQIDPNAFDALTELQVLRLHSNSLQHVPQRWFKNINKLKELDLSQNFLAKEIGDAKFLHLLHNLVNLDLSFNYDLQVYHAVINLSDAFSSLKKLKVLRIKGYVFKELNSLNLFPLHNLPNLEVLDLGTNFIKIANLSIFNQFKTLKFIDLSVNKISPSGDSPEGGFCSNRRTSVEGHGPQVLETLHYFRYDEYARSCRSKSKEPPSFLPLNEDCYMYGQTLDLSRNNIFFIKPSDFQHLSFLKCLNLSGNSISQTLNGSEFQPLVELKYLDFSNNRLDLLYSTAFEELHNLEVLDISSNSHYFQSEGITHMLNFTKNLKVLRKLMMNYNDIATSTSRTMESESLQILEFRGNHLDILWRDGDNRYLKFFKNLLNLEELDISENSLSFLPLGVFDSMPPNLKTLSLAKNGLKSFSWERLQSLKNLETLDLSFNQLKTVPERLSNCSRSLKKLILKNNQIRCLTKYFLQGAFQLRHLDLSSNKIQVIQKTSFPENVLNNLNILFLHHNRFLCNCDAVWFVWWVNHTEVTIPYLATDVTCMGPGAHKGQSVVSLDLYTCELDLTNFILFSLSISAVLSLMMITIANHLYFWDVWYSYHFCKAKIKGYRRLISPNSCYDAFIVYDTKDPAVTEWVLDELVAKLEDPREKCFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPLQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVTYSQVFKETA", "length": 1055 }, "evidence": [ { "id": "A0A1L4FML6", "url": "https://omabrowser.org/oma/group/A0A1L4FML6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P58681-1", "protein_name": "Toll-like receptor 7", "gene_name": "Tlr7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVFSMWTRKRQILIFLNMLLVSRVFGFRWFPKTLPCEVKVNIPEAHVIVDCTDKHLTEIPEGIPTNTTNLTLTINHIPSISPDSFRRLNHLEEIDLRCNCVPVLLGSKANVCTKRLQIRPGSFSGLSDLKALYLDGNQLLEIPQDLPSSLHLLSLEANNIFSITKENLTELVNIETLYLGQNCYYRNPCNVSYSIEKDAFLVMRNLKVLSLKDNNVTAVPTTLPPNLLELYLYNNIIKKIQENDFNNLNELQVLDLSGNCPRCYNVPYPCTPCENNSPLQIHDNAFNSLTELKVLRLHSNSLQHVPPTWFKNMRNLQELDLSQNYLAREIEEAKFLHFLPNLVELDFSFNYELQVYHASITLPHSLSSLENLKILRVKGYVFKELKNSSLSVLHKLPRLEVLDLGTNFIKIADLNIFKHFENLKLIDLSVNKISPSEESREVGFCPNAQTSVDRHGPQVLEALHYFRYDEYARSCRFKNKEPPSFLPLNADCHIYGQTLDLSRNNIFFIKPSDFQHLSFLKCLNLSGNTIGQTLNGSELWPLRELRYLDFSNNRLDLLYSTAFEELQSLEVLDLSSNSHYFQAEGITHMLNFTKKLRLLDKLMMNDNDISTSASRTMESDSLRILEFRGNHLDVLWRAGDNRYLDFFKNLFNLEVLDISRNSLNSLPPEVFEGMPPNLKNLSLAKNGLKSFFWDRLQLLKHLEILDLSHNQLTKVPERLANCSKSLTTLILKHNQIRQLTKYFLEDALQLRYLDISSNKIQVIQKTSFPENVLNNLEMLVLHHNRFLCNCDAVWFVWWVNHTDVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNLILFSVSISSVLFLMVVMTTSHLFFWDMWYIYYFWKAKIKGYQHLQSMESCYDAFIVYDTKNSAVTEWVLQELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTQKYAKTESFKMAFYLSHQRLLDEKVDVIILIFLEKPLQKSKFLQLRKRLCRSSVLEWPANPQAHPYFWQCLKNALTTDNHVAYSQMFKETV", "length": 1050 }, "evidence": [ { "id": "A0A1L4FML6", "url": "https://omabrowser.org/oma/group/A0A1L4FML6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVFPMWTLKRQILILFNIILISKLLGARWFPKTLPCDVTLDVPKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVPIPLGSKNNMCIKRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTAVPTVLPSTLTELYLYNNMIAKIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPSGDSSEVGFCSNARTSVESYEPQVLEQLHYFRYDKYARSCRFKNKEASFMSVNESCYKYGQTLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWVNHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNLILFSLSISVSLFLMVMMTASHLYFWDVWYIYHFCKAKIKGYQRLISPDCCYDAFIVYDTKDPAVTEWVLAELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVAYSQVFKETV", "length": 1049 }, "evidence": [ { "id": "A0A1L4FML6", "url": "https://omabrowser.org/oma/group/A0A1L4FML6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 23, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "positive regulation of interferon-alpha production", "id": "GO:0032727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032727", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "positive regulation of chemokine production", "id": "GO:0032722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032722", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "cellular response to mechanical stimulus", "id": "GO:0071260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071260", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "regulation of protein phosphorylation", "id": "GO:0001932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001932", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "canonical NF-kappaB signal transduction", "id": "GO:0007249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007249", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "positive regulation of macrophage cytokine production", "id": "GO:0060907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060907", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "toll-like receptor 7 signaling pathway", "id": "GO:0034154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034154", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "response to cGMP", "id": "GO:0070305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070305", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "positive regulation of interferon-beta production", "id": "GO:0032728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032728", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "early phagosome", "id": "GO:0032009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032009", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" }, { "name": "siRNA binding", "id": "GO:0035197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035197", "evidence": [ { "database": "UniProtKB", "id": "A0A1L4FML6", "url": "https://www.uniprot.org/uniprot/A0A1L4FML6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1046, "end_pos": 1048, "annotation": "n_glycosylation_sequon" }, { "start_pos": 128, "end_pos": 130, "annotation": 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