{ "uniprot_canonical_ac": "A0A1D5PLZ3-1", "uniprot_ac": "A0A1D5PLZ3", "uniprot_id": "A0A1D5PLZ3_CHICK", "mass": { "chemical_mass": 37919.0, "monoisotopic_mass": 37919.0 }, "refseq": { "ac": "NP_001186388", "name": "retinol dehydrogenase 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186388" }, "gene_names": [ { "name": "RDH10", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3", "id": "A0A1D5PLZ3" }, { "name": "RDH10", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186388", "id": "NP_001186388" } ], "protein_names": [ { "name": "NADP-retinol dehydrogenase", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLZ3/entry#names_and_taxonomy", "id": "A0A1D5PLZ3" }, { "name": "1.1.1.300", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLZ3/entry#names_and_taxonomy", "id": "A0A1D5PLZ3" }, { "name": "retinol dehydrogenase 10", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186388", "id": "NP_001186388" } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.122416.1, CR382432.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000043.1. On Dec 9, 2010 this sequence version replaced XP_418296.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186388" } ] }, { "annotation": "Data show that Stra6 and Rdh10 co-localised with a retinaldehyde dehydrogenase (Raldh), as might be expected allowing retinol to be taken into the cell and converted into RA.", "evidence": [ { "database": "RefSeq", "id": "NP_001186388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186388" }, { "database": "PubMed", "id": "20563989", "url": "https://glygen.org/publication/PubMed/20563989" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RDH10", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3", "locus": { "chromosome": "2", "start_pos": 117471517, "end_pos": 117446713, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003582", "url": "https://www.ensembl.org/id/ENSGALG00010003582" } ] } } ], "crossref": [ { "id": "A0A1D5PLZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PLZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000034346", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000034346", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05339", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05339", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420183", "url": "https://www.ncbi.nlm.nih.gov/gene/420183", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420183", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420183", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TVCPTYI", "url": "https://omabrowser.org/oma/group/TVCPTYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PLZ3", "url": "https://www.orthodb.org/?gene=A0A1D5PLZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24322:SF736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24322:SF736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001186388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186388", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25033", "url": "https://www.rhea-db.org/rhea/25033", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLZ3-1", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNILLELFVVTFRVLWAFVLAAAKWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRELAEAAPKVAGDGEKDALPHCSLQVYTYTCDVGKRENVYTTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPKMLEMNHGHIVTVASSLGLFSTAGVEDYCASKFGAVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPEYCVKQAMRAILTDQPMICTPRLMYMVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "length": 339, "header": "tr|A0A1D5PLZ3-1|A0A1D5PLZ3_CHICK Isoform 1 of NADP-retinol dehydrogenase OS=Gallus gallus OX=9031 GN=RDH10 PE=1 SV=1 CANONICAL=A0A1D5PLZ3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLZ3/entry#A0A1D5PLZ3-1", "sequence": { "sequence": "MNILLELFVVTFRVLWAFVLAAAKWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRELAEAAPKVAGDGEKDALPHCSLQVYTYTCDVGKRENVYTTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPKMLEMNHGHIVTVASSLGLFSTAGVEDYCASKFGAVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPEYCVKQAMRAILTDQPMICTPRLMYMVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "length": 339, "header": "tr|A0A1D5PLZ3-1|A0A1D5PLZ3_CHICK Isoform 1 of NADP-retinol dehydrogenase OS=Gallus gallus OX=9031 GN=RDH10 PE=1 SV=1 CANONICAL=A0A1D5PLZ3-1" }, "locus": { "chromosome": "2", "start_pos": 117470251, "end_pos": 117447000, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008335.1", "url": "https://www.ensembl.org/id/ENSGALT00010008335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004926.1", "url": "https://www.ensembl.org/id/ENSGALP00010004926.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The expression of Stra6 and Rdh10 in the avian embryo and their contribution to the generation of retinoid signatures.", "journal": "The International journal of developmental biology", "date": "2010", "authors": "Reijntjes Susan, Zile Maija H, Maden Malcolm", "evidence": [ { "database": "RefSeq", "id": "NP_001186388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186388" } ], "reference": [ { "type": "PubMed", "id": "20563989", "url": "https://glygen.org/publication/PubMed/20563989" } ] } ], "pathway": [ { "id": "gga:420183", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420183", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q80ZF7-1", "protein_name": "Retinol dehydrogenase 10", "gene_name": "Rdh10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNIVVEFFLVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "length": 341 }, "evidence": [ { "id": "A0A1D5PLZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PLZ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8HZT6-1", "protein_name": "Retinol dehydrogenase 10", "gene_name": "RDH10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "length": 341 }, "evidence": [ { "id": "A0A1D5PLZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PLZ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IZV5-1", "protein_name": "Retinol dehydrogenase 10", "gene_name": "RDH10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "length": 341 }, "evidence": [ { "id": "A0A1D5PLZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PLZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VCH7-1", "protein_name": "Retinol dehydrogenase 10", "gene_name": "Rdh10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGKGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMRAILTDQPMVCTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "length": 341 }, "evidence": [ { "id": "A0A1D5PLZ3", "url": "https://omabrowser.org/oma/group/A0A1D5PLZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "primary lung bud formation", "id": "GO:0060431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060431", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "nose development", "id": "GO:0043584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043584", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "retinoic acid biosynthetic process", "id": "GO:0002138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002138", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "neural crest cell development", "id": "GO:0014032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014032", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "embryonic camera-type eye development", "id": "GO:0031076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031076", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "embryonic forelimb morphogenesis", "id": "GO:0035115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035115", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "retinal metabolic process", "id": "GO:0042574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042574", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "metanephros development", "id": "GO:0001656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001656", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "ear development", "id": "GO:0043583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043583", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "embryonic viscerocranium morphogenesis", "id": "GO:0048703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048703", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "bud elongation involved in lung branching", "id": "GO:0060449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060449", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "gonad development", "id": "GO:0008406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008406", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "all-trans-retinol dehydrogenase (NAD+) activity", "id": "GO:0004745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004745", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" }, { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLZ3", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25033", "name": "", "equation": "all-trans-retinol + NADP(+) = all-trans-retinal + H(+) + NADPH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PLZ3-1", "A0A8V1A091-1", "E1BVD1-1", "A0A8V0YKB8-1", "A0A8V0YJV4-1" ], "evidence": [ { "id": "25033", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25033" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PLZ3", "gene_name": "RDH10", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + H(+) + NADPH.", "evidence": [ { "id": "A0A1D5PLZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A1D5PLZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A1D5PLZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YJV4", "gene_name": "AKR1B1", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + H(+) + NADPH.", "evidence": [ { "id": "A0A8V0YJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YJV4" } ] }, { "ec_number": "1.1.1.21", "activity": "an alditol + NADP(+) = an aldose + H(+) + NADPH.", "evidence": [ { "id": "A0A8V0YJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YJV4" } ] }, { "ec_number": "1.1.1.21", "activity": "", "evidence": [ { "id": "A0A8V0YJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YJV4" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A8V0YJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YJV4" } ] } ] }, { "uniprot_ac": "A0A8V0YKB8", "gene_name": "AKR1E2", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + H(+) + NADPH.", "evidence": [ { "id": "A0A8V0YKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YKB8" } ] }, { "ec_number": "1.1.1.21", "activity": "an alditol + NADP(+) = an aldose + H(+) + NADPH.", "evidence": [ { "id": "A0A8V0YKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YKB8" } ] }, { "ec_number": "1.1.1.21", "activity": "", "evidence": [ { "id": "A0A8V0YKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YKB8" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A8V0YKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8V0YKB8" } ] } ] }, { "uniprot_ac": "A0A8V1A091", "gene_name": "RDH8L", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + H(+) + NADPH.", "evidence": [ { "id": "A0A8V1A091", "database": "UniProtKB", "url": 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