{ "uniprot_canonical_ac": "A0A1D5PI14-1", "uniprot_ac": "A0A1D5PI14", "uniprot_id": "A0A1D5PI14_CHICK", "mass": { "chemical_mass": 56396.0, "monoisotopic_mass": 56396.0 }, "refseq": {}, "gene_names": [ { "name": "TBL1X", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1D5PI14", "id": "A0A1D5PI14" } ], "protein_names": [ { "name": "Transducin beta like 1X-linked", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14/entry#names_and_taxonomy", "id": "A0A1D5PI14" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PI14", "url": "https://www.uniprot.org/uniprot/A0A1D5PI14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBL1X", "url": "https://www.uniprot.org/uniprot/A0A1D5PI14", "locus": { "chromosome": "1", "start_pos": 125335589, "end_pos": 125535463, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001599", "url": "https://www.ensembl.org/id/ENSGALG00010001599" } ] } } ], "crossref": [ { "id": "A0A1D5PI14", "url": "https://alphafold.ebi.ac.uk/entry/A0A1D5PI14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000040006", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000040006", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22846", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22846", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22846:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22846:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF08513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08513", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PI14", "url": "https://www.uniprot.org/uniprot/A0A1D5PI14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PI14-1", "url": "https://www.uniprot.org/uniprot/A0A1D5PI14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2X1", "url": "https://www.uniprot.org/uniprot/A0A8V0X2X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2X1-1", "url": "https://www.uniprot.org/uniprot/A0A8V0X2X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X649", "url": "https://www.uniprot.org/uniprot/A0A8V0X649", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X649-1", "url": "https://www.uniprot.org/uniprot/A0A8V0X649-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X983", "url": "https://www.uniprot.org/uniprot/A0A8V0X983", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X983-1", "url": "https://www.uniprot.org/uniprot/A0A8V0X983-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAATAATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRGTGGIFEVCWNARGDKVGASASDGSKKCTFE", "length": 521, "header": "tr|A0A1D5PI14-1|A0A1D5PI14_CHICK Isoform 1 of Transducin beta like 1X-linked OS=Gallus gallus OX=9031 GN=TBL1X PE=1 SV=2 CANONICAL=A0A1D5PI14-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PI14-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14/entry#A0A1D5PI14-1", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAATAATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRGTGGIFEVCWNARGDKVGASASDGSKKCTFE", "length": 521, "header": "tr|A0A1D5PI14-1|A0A1D5PI14_CHICK Isoform 1 of Transducin beta like 1X-linked OS=Gallus gallus OX=9031 GN=TBL1X PE=1 SV=2 CANONICAL=A0A1D5PI14-1" }, "locus": { "chromosome": "1", "start_pos": 125392603, "end_pos": 125340685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003659.1", "url": "https://www.ensembl.org/id/ENSGALT00010003659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002056.1", "url": "https://www.ensembl.org/id/ENSGALP00010002056.1" } ] } }, { "isoform_ac": "A0A8V0X2X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14/entry#A0A8V0X2X1-1", "sequence": { "sequence": "MQINLCFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAATAATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK", "length": 509, "header": "tr|A0A8V0X2X1-1|A0A8V0X2X1_CHICK Computationally mapped isoform of Transducin beta like 1X-linked OS=Gallus gallus OX=9031 GN=TBL1X PE=1 SV=1 CANONICAL=A0A1D5PI14-1" }, "locus": { "chromosome": "1", "start_pos": 125382232, "end_pos": 125339955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003654.1", "url": "https://www.ensembl.org/id/ENSGALT00010003654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002053.1", "url": "https://www.ensembl.org/id/ENSGALP00010002053.1" } ] } }, { "isoform_ac": "A0A8V0X649-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14/entry#A0A8V0X649-1", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAATAATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQYIATEAPEASLKSAGMLEETKWEQAHQMDRFVF", "length": 514, "header": "tr|A0A8V0X649-1|A0A1D5PI14_CHICK Computationally mapped isoform of Transducin beta like 1X-linked OS=Gallus gallus OX=9031 GN=TBL1X PE=1 SV=1 CANONICAL=A0A1D5PI14-1" }, "locus": { "chromosome": "1", "start_pos": 125392603, "end_pos": 125339969, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003661.1", "url": "https://www.ensembl.org/id/ENSGALT00010003661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002057.1", "url": "https://www.ensembl.org/id/ENSGALP00010002057.1" } ] } }, { "isoform_ac": "A0A8V0X983-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI14/entry#A0A8V0X983-1", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQVLF", "length": 467, "header": "tr|A0A8V0X983-1|A0A1D5PI14_CHICK Computationally mapped isoform of Transducin beta like 1X-linked OS=Gallus gallus OX=9031 GN=TBL1X PE=1 SV=1 CANONICAL=A0A1D5PI14-1" }, "locus": { "chromosome": "1", "start_pos": 125392603, "end_pos": 125342088, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003658.1", "url": "https://www.ensembl.org/id/ENSGALT00010003658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002055.1", "url": "https://www.ensembl.org/id/ENSGALP00010002055.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PI14", "url": "https://www.uniprot.org/uniprot/A0A1D5PI14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PI14", "url": "https://www.uniprot.org/uniprot/A0A1D5PI14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A1D5PI14-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 521, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A1D5PI14-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 40, "end_pos": 42 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }