{ "uniprot_canonical_ac": "A0A0U1RPC5-1", "uniprot_ac": "A0A0U1RPC5", "uniprot_id": "A0A0U1RPC5_MOUSE", "mass": { "chemical_mass": 74490.0, "monoisotopic_mass": 74490.0 }, "refseq": {}, "gene_names": [ { "name": "Zfp109", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0U1RPC5", "id": "A0A0U1RPC5" } ], "protein_names": [ { "name": "Zinc finger protein 109", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RPC5/entry#names_and_taxonomy", "id": "A0A0U1RPC5" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RPC5", "url": "https://www.uniprot.org/uniprot/A0A0U1RPC5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "gene": [ { "name": "Zfp109", "url": "https://www.uniprot.org/uniprot/A0A0U1RPC5", "locus": { "chromosome": "7", "start_pos": 23926997, "end_pos": 23936985, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000074283", "url": "https://www.ensembl.org/id/ENSMUSG00000074283" } ] } } ], "crossref": [ { "id": "A0A0U1RPC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A0U1RPC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSMUSG00000074283", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000074283", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "56869", "url": "https://www.ncbi.nlm.nih.gov/gene/56869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "1929099", "url": "http://www.informatics.jax.org/marker/MGI:1929099", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "Q9R166", "url": "https://www.orthodb.org/?gene=Q9R166", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "A0A0U1RPC5", "url": "https://www.uniprot.org/uniprot/A0A0U1RPC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0U1RPC5-1", "url": "https://www.uniprot.org/uniprot/A0A0U1RPC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9R166", "url": "https://www.uniprot.org/uniprot/Q9R166", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9R166-1", "url": "https://www.uniprot.org/uniprot/Q9R166-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHAGMETFWRLFQEAVTFRDVAVVFSEEELGLLDAAQRKLYHDVMLENFRNLLAVGGQVPNKMENLHTTGVRCLSLGQLPCGHMASHDANKLARAPEGVINTQGMVSYFPEQCHFSCHRGPEEPPWASKDNGCLEILTNDHSSITESQKFLSGIAQCSWSKKHLSKRQNYQKHCVQTPVKTKPRRLLAPGIDRMSCVSHQDNNTLHKGDKGQSNSDFDKLTFPVSPVTPHHVYTERKSYKCSKAQEAFIDRPTLELHQQDLVGKKSPVRSTYEVSRHSSIQKSVHAGTKRYWCHECGKAFSQSSALQTHRRVHTGEKPYRCDSCGKAFTQWSVLHAHQRIHTGEKPYKCGDCGRRFRFSSNLHIHQRVHTGEKPYKCHVCGKCFRFRFYSHQRVHTGEKPYKCDECGKGFTSASNVKVHQRVHTGVKPFCCNVCGKCFSRSFHLHTHQRVHTGEKLYKCDACGKAFSQRSSLQVHRLIHTGEKPYKCEECGKGFTSASSFQGHQRVHTGEKPFHCDVCGKDFSRSSYLQIHQRMHTGEKPYKCDSCGKAFSQRAHLQVHQRTHTGEKPFKCEECGKEFRQRSGLSSHQIVHKEEKPYTCWECGKGFSQPSLFERHRRVHTGERPYICGTCCKGFSQRSHLVKHQRVHSAANL", "length": 652, "header": "tr|A0A0U1RPC5-1|A0A0U1RPC5_MOUSE Isoform 1 of Zinc finger protein 109 OS=Mus musculus OX=10090 GN=Zfp109 PE=4 SV=1 CANONICAL=A0A0U1RPC5-1" }, "isoforms": [ { "isoform_ac": "A0A0U1RPC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RPC5/entry#A0A0U1RPC5-1", "sequence": { "sequence": "MHAGMETFWRLFQEAVTFRDVAVVFSEEELGLLDAAQRKLYHDVMLENFRNLLAVGGQVPNKMENLHTTGVRCLSLGQLPCGHMASHDANKLARAPEGVINTQGMVSYFPEQCHFSCHRGPEEPPWASKDNGCLEILTNDHSSITESQKFLSGIAQCSWSKKHLSKRQNYQKHCVQTPVKTKPRRLLAPGIDRMSCVSHQDNNTLHKGDKGQSNSDFDKLTFPVSPVTPHHVYTERKSYKCSKAQEAFIDRPTLELHQQDLVGKKSPVRSTYEVSRHSSIQKSVHAGTKRYWCHECGKAFSQSSALQTHRRVHTGEKPYRCDSCGKAFTQWSVLHAHQRIHTGEKPYKCGDCGRRFRFSSNLHIHQRVHTGEKPYKCHVCGKCFRFRFYSHQRVHTGEKPYKCDECGKGFTSASNVKVHQRVHTGVKPFCCNVCGKCFSRSFHLHTHQRVHTGEKLYKCDACGKAFSQRSSLQVHRLIHTGEKPYKCEECGKGFTSASSFQGHQRVHTGEKPFHCDVCGKDFSRSSYLQIHQRMHTGEKPYKCDSCGKAFSQRAHLQVHQRTHTGEKPFKCEECGKEFRQRSGLSSHQIVHKEEKPYTCWECGKGFSQPSLFERHRRVHTGERPYICGTCCKGFSQRSHLVKHQRVHSAANL", "length": 652, "header": "tr|A0A0U1RPC5-1|A0A0U1RPC5_MOUSE Isoform 1 of Zinc finger protein 109 OS=Mus musculus OX=10090 GN=Zfp109 PE=4 SV=1 CANONICAL=A0A0U1RPC5-1" }, "locus": { "chromosome": "7", "start_pos": 23936546, "end_pos": 23927476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000206960.2", "url": "https://www.ensembl.org/id/ENSMUST00000206960.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000145925.2", "url": "https://www.ensembl.org/id/ENSMUSP00000145925.2" } ] } }, { "isoform_ac": "Q9R166-1", "url": "https://www.uniprot.org/uniprotkb/A0A0U1RPC5/entry#Q9R166-1", "sequence": { "sequence": "MTKLQEAVTFRDVAVVFSEEELGLLDAAQRKLYHDVMLENFRNLLAVGGQVPNKMENLHTTGVRCLSLGQLPCGHMASHDANKLARAPEGVINTQGMVSYFPEQCHFSCHRGPEEPPWASKDNGCLEILTNDHSSITESQKFLSGIAQCSWSKKHLSKRQNYQKHCVQTPVKTKPRRLLAPGIDRMSCVSHQDNNTLHKGDKGQSNSDFDKLTFPVSPVTPHHVYTERKSYKCSKAQEAFIDRPTLELHQQDLVGKKSPVRSTYEVSRHSSIQKSVHAGTKRYWCHECGKAFSQSSALQTHRRVHTGEKPYRCDSCGKAFTQWSVLHAHQRIHTGEKPYKCGDCGRRFRFSSNLHIHQRVHTGEKPYKCHVCGKCFRFRFYSHQRVHTGEKPYKCDECGKGFTSASNVKVHQRVHTGVKPFCCNVCGKCFSRSFHLHTHQRVHTGEKLYKCDACGKAFSQRSSLQVHRLIHTGEKPYKCEECGKGFTSASSFQGHQRVHTGEKPFHCDVCGKDFSRSSYLQIHQRMHTGEKPYKCDSCGKAFSQRAHLQVHQRTHTGEKPFKCEECGKEFRQRSGLSSHQIVHKEEKPYTCWECGKGFSQPSLFERHRRVHTGERPYICGTCCKGFSQRSHLVKHQRVHSAANL", "length": 644, "header": "tr|Q9R166-1|Q9R166_MOUSE Computationally mapped isoform of Zinc finger protein 109 OS=Mus musculus OX=10090 GN=Zfp109 PE=2 SV=1 CANONICAL=A0A0U1RPC5-1" }, "locus": { "chromosome": "7", "start_pos": 23936057, "end_pos": 23927476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000037448.7", "url": "https://www.ensembl.org/id/ENSMUST00000037448.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000045498.7", "url": "https://www.ensembl.org/id/ENSMUSP00000045498.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.", "journal": "Genome Res.", "date": "2003", "authors": "Shannon M, Hamilton AT, Gordon L, Branscomb E, Stubbs L", "evidence": [ { "database": "UniProtKB", "id": "Q9R166", "url": "https://www.uniprot.org/uniprot/Q9R166" } ], "reference": [ { "type": "PubMed", "id": "12743021", "url": "https://glygen.org/publication/PubMed/12743021" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RPC5", "url": "https://www.uniprot.org/uniprot/A0A0U1RPC5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RPC5", "url": "https://www.uniprot.org/uniprot/A0A0U1RPC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RPC5", "url": "https://www.uniprot.org/uniprot/A0A0U1RPC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A0U1RPC5", "url": "https://www.uniprot.org/uniprot/A0A0U1RPC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A0U1RPC5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 652, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0U1RPC5-F1.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": 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"count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }