{ "uniprot_canonical_ac": "A0A0G2KA92-1", "uniprot_ac": "A0A0G2KA92", "uniprot_id": "A0A0G2KA92_RAT", "mass": { "chemical_mass": 212652.0, "monoisotopic_mass": 212652.0 }, "refseq": {}, "gene_names": [ { "name": "Chd2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92" } ], "protein_names": [ { "name": "DNA helicase", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA92/entry#names_and_taxonomy", "id": "A0A0G2KA92" }, { "name": "3.6.4.12", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA92/entry#names_and_taxonomy", "id": "A0A0G2KA92" } ], "function": [], "disease": [ { "disease_id": "DOID:0050834", "recommended_name": { "id": "DOID:0050834", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050834", "name": "CHARGE syndrome", "description": "A syndrome that is characterized by a pattern of congenital anomalies including choanal atresia and malformations of the heart, inner ear, and retina." }, "synonyms": [ { "id": "DOID:0050834", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050834", "name": "CHARGE association", "description": "" }, { "id": "MONDO:0008965", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008965", "name": "CHARGE syndrome", "description": "CHARGE syndrome is a multiple congenital anomaly syndrome characterized by the variable combination of multiple anomalies, mainly Coloboma; Choanal atresia/stenosis; Cranial nerve dysfunction; Characteristic ear anomalies (known as the major 4 C's)." }, { "id": "MONDO:0008965", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008965", "name": "CHARGE association", "description": "" }, { "id": "MONDO:0008965", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008965", "name": "CHARGE syndrome", "description": "" }, { "id": "MONDO:0008965", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008965", "name": "Hall-Hittner syndrome", "description": "" }, { "id": "MONDO:0008965", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008965", "name": "coloboma, heart defects, choanal atresia, retardation of Growth and development, genital abnormalities, and Ear anomalies association", "description": "" }, { "id": "MONDO:0008965", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008965", "name": "coloboma, heart malformation, choanal atresia, retardation of Growth and development, genital abnormalities, and Ear malformations (CHARGE) association", "description": "" }, { "id": "MONDO:0008965", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008965", "name": "coloboma-heart defects-atresia choanae-retardation of growth and development-genitourinary problems-ear abnormalities syndrome", "description": "" }, { "id": "MONDO:0008965", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008965", "name": "Charge association--coloboma, heart anomaly, choanal atresia, retardation, genital and Ear anomalies", "description": "" }, { "id": "MONDO:0008965", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008965", "name": "coloboma, heart anomaly, choanal atresia, retardation, genital and ear anomalies", "description": "" }, { "id": "MIM:214800", "resource": "MIM", "url": "https://www.omim.org/entry/214800", "name": "CHARGE syndrome", "description": "CHARGE syndrome" } ], "evidence": [ { "id": "0050834", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0050834" } ] }, { "disease_id": "DOID:0060041", "recommended_name": { "id": "DOID:0060041", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior." }, "synonyms": [], "evidence": [ { "id": "0060041", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ] }, { "disease_id": "DOID:0060475", "recommended_name": { "id": "DOID:0060475", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060475", "name": "myoclonic-atonic epilepsy", "description": "An idiopathic generalized epilepsy characterized by onset of multiple seizure types in the first few years of life and associated with poor prognosis. Affected individuals have cognitive regression and intellectual disability and that has_material_basis_in heterozygous mutation in the SLC6A1 gene on chromosome 3p25." }, "synonyms": [ { "id": "DOID:0060475", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060475", "name": "EEOC", "description": "" }, { "id": "DOID:0060475", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060475", "name": "childhood onset epileptic encephalopathy", "description": "" }, { "id": "MONDO:0014633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014633", "name": "myoclonic-atonic epilepsy", "description": "" }, { "id": "MONDO:0014633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014633", "name": "Myoclonic Atonic Epilepsy", "description": "" }, { "id": "MONDO:0014633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014633", "name": "myoclonic-atonic epilepsy", "description": "" }, { "id": "MONDO:0014633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014633", "name": "mae", "description": "" }, { "id": "MIM:616421", "resource": "MIM", "url": "https://www.omim.org/entry/616421", "name": "Myoclonic-atonic epilepsy", "description": "Myoclonic-atonic epilepsy" } ], "evidence": [ { "id": "0060475", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0060475" } ] }, { "disease_id": "DOID:0081325", "recommended_name": { "id": "DOID:0081325", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0081325", "name": "developmental and epileptic encephalopathy 94", "description": "A developmental and epileptic encephalopathy characterized by onset of multiple seizure types in the first few years of life and associated with poor prognosis and that has_material_basis_in heterozygous mutation in the CHD2 gene on chromosome 15q26." }, "synonyms": [ { "id": "MONDO:0014150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014150", "name": "developmental and epileptic encephalopathy 94", "description": "An idiopathic generalized epilepsy characterized by onset of multiple seizure types in the first few years of life and associated with poor prognosis. Affected individuals have cognitive regression and intellectual disability." }, { "id": "MONDO:0014150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014150", "name": "DEE94", "description": "" }, { "id": "MONDO:0014150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014150", "name": "EEOC", "description": "" }, { "id": "MONDO:0014150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014150", "name": "childhood onset epileptic encephalopathy", "description": "" }, { "id": "MONDO:0014150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014150", "name": "developmental and epileptic encephalopathy 94", "description": "" }, { "id": "MONDO:0014150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014150", "name": "CHCHD10-related disorders", "description": "" }, { "id": "MONDO:0014150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014150", "name": "CHD2 myoclonic encephalopathy", "description": "" }, { "id": "MONDO:0014150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014150", "name": "childhood-onset epileptic encephalopathy", "description": "" }, { "id": "MONDO:0014150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014150", "name": "epileptic encephalopathy, childhood-onset", "description": "" }, { "id": "MIM:615369", "resource": "MIM", "url": "https://www.omim.org/entry/615369", "name": "Developmental and epileptic encephalopathy 94", "description": "Developmental and epileptic encephalopathy 94" } ], "evidence": [ { "id": "0081325", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0081325" } ] }, { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" } ], "evidence": [ { "id": "10283", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Chd2", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "locus": { "chromosome": "1", "start_pos": 127190059, "end_pos": 127300502, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000012716", "url": "https://www.ensembl.org/id/ENSRNOG00000012716" } ] } } ], "crossref": [ { "id": "A0A0G2KA92", "url": "https://alphafold.ebi.ac.uk/entry/A0A0G2KA92", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSRNOG00000012716", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000012716", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18666", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18666", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "308738", "url": "https://www.ncbi.nlm.nih.gov/gene/308738", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:308738", "url": "https://www.genome.jp/dbget-bin/www_bget?rno:308738", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REICQQH", "url": "https://omabrowser.org/oma/group/REICQQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A096MJY0", "url": "https://www.orthodb.org/?gene=A0A096MJY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A0G2KA92", "url": "https://www.orthodb.org/?gene=A0A0G2KA92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "D4AD08", "url": "https://www.orthodb.org/?gene=D4AD08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45623", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45623", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45623:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45623:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF13907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13907", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF18375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18375", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_006229431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006229431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1310056", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310056", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A096MJY0", "url": "https://www.uniprot.org/uniprot/A0A096MJY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A096MJY0-1", "url": "https://www.uniprot.org/uniprot/A0A096MJY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2KA92-1", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GCU8", "url": "https://www.uniprot.org/uniprot/A0A8I6GCU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GCU8-1", "url": "https://www.uniprot.org/uniprot/A0A8I6GCU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D4AD08", "url": "https://www.uniprot.org/uniprot/D4AD08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D4AD08-1", "url": "https://www.uniprot.org/uniprot/D4AD08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHKPREEHLSLSPCIFTWYQTFSQLTFEEEKLSHSASEEASASDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDDQEQGSSAESEAEQKKVKARRPIPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASHGPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGGGNNAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT", "length": 1840, "header": "tr|A0A0G2KA92-1|A0A0G2KA92_RAT Isoform 1 of DNA helicase OS=Rattus norvegicus OX=10116 GN=Chd2 PE=1 SV=1 CANONICAL=A0A0G2KA92-1" }, "isoforms": [ { "isoform_ac": "A0A096MJY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA92/entry#A0A096MJY0-1", "sequence": { "sequence": "MMRNKDKSQEEDSSLHSNASSHSASEEASASDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDDQEQGSSAESEAEQKKVKARRPIPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGVDLNPFAATGASTTVYAVEANGDPSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASHGPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGGGNNAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT", "length": 1834, "header": "tr|A0A096MJY0-1|A0A0G2KA92_RAT Computationally mapped isoform of DNA helicase OS=Rattus norvegicus OX=10116 GN=Chd2 PE=1 SV=2 CANONICAL=A0A0G2KA92-1" }, "locus": { "chromosome": "1", "start_pos": 127299587, "end_pos": 127191062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000076300.3", "url": "https://www.ensembl.org/id/ENSRNOT00000076300.3" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000068303.2", "url": "https://www.ensembl.org/id/ENSRNOP00000068303.2" } ] } }, { "isoform_ac": "A0A0G2KA92-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA92/entry#A0A0G2KA92-1", "sequence": { "sequence": "MAHKPREEHLSLSPCIFTWYQTFSQLTFEEEKLSHSASEEASASDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDDQEQGSSAESEAEQKKVKARRPIPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASHGPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGGGNNAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT", "length": 1840, "header": "tr|A0A0G2KA92-1|A0A0G2KA92_RAT Isoform 1 of DNA helicase OS=Rattus norvegicus OX=10116 GN=Chd2 PE=1 SV=1 CANONICAL=A0A0G2KA92-1" }, "locus": { "chromosome": "1", "start_pos": 127296139, "end_pos": 127191062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000090149.2", "url": "https://www.ensembl.org/id/ENSRNOT00000090149.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000075309.1", "url": "https://www.ensembl.org/id/ENSRNOP00000075309.1" } ] } }, { "isoform_ac": "A0A8I6GCU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA92/entry#A0A8I6GCU8-1", "sequence": { "sequence": "MMRNKDKSQEEDSSLHSNASSHSASEEASASDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASHGPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGGGNNAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT", "length": 1791, "header": "tr|A0A8I6GCU8-1|A0A8I6GCU8_RAT Computationally mapped isoform of DNA helicase OS=Rattus norvegicus OX=10116 GN=Chd2 PE=1 SV=1 CANONICAL=A0A0G2KA92-1" }, "locus": { "chromosome": "1", "start_pos": 127299587, "end_pos": 127191062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000098073.1", "url": "https://www.ensembl.org/id/ENSRNOT00000098073.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000085288.1", "url": "https://www.ensembl.org/id/ENSRNOP00000085288.1" } ] } }, { "isoform_ac": "D4AD08-1", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KA92/entry#D4AD08-1", "sequence": { "sequence": "MAHKPREEHLSLSPCIFTWYQTFSQLTFEEEKLSHSASEEASASDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDDQEQGSSAESEAEQKKVKARRPIPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQSCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEVNVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIRAPEDSERETGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRLVASAPLELECIARDAELVDKSVADLKRLGELVHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVTSGEEAKLKKRKPRVKKENKAPRLKDEHGLELSSPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKEKKKSKDKKEKVKGGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRSCLLKIGDRIAECLRAYSEQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDTLGGKKPFRPEASGSSRDSLISQSHASHNLHPQKPHLPASHGPQMHGHPRDTYSHPNKRHFSNADRGDWQRERKFNYGGGNNAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPTLHTALSDPRSPPAQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT", "length": 1834, "header": "tr|D4AD08-1|D4AD08_RAT Computationally mapped isoform of DNA helicase OS=Rattus norvegicus OX=10116 GN=Chd2 PE=1 SV=2 CANONICAL=A0A0G2KA92-1" }, "locus": { "chromosome": "1", "start_pos": 127296139, "end_pos": 127191062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000055829.4", "url": "https://www.ensembl.org/id/ENSRNOT00000055829.4" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000052684.3", "url": "https://www.ensembl.org/id/ENSRNOP00000052684.3" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 1801, "end_pos": 1801, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "D4AD08", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D4AD08" } ], "site_lbl": "Ser1801" }, { "start_pos": 1807, "end_pos": 1807, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "D4AD08", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D4AD08" } ], "site_lbl": "Ser1807" }, { "start_pos": 1813, "end_pos": 1813, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "D4AD08", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D4AD08" } ], "site_lbl": "Ser1813" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "A0A096MJY0", "url": "https://www.uniprot.org/uniprot/A0A096MJY0" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] } ], "pathway": [ { "id": "rno:308738", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?rno:308738", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z847-1", "protein_name": "DNA helicase", "gene_name": "CHD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMRNKDKSQGEEGSVHSNASSHSASEEASGSDSASQSESEQGSEQGSESNSSSESSESQSESESESTGSKSQQTPPETKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKDEASSESENESPKRRGQKQVKRKKKWKREISGEEEDEDGGDQGTSAESEPEPKRIKAKRPVQRRTMAKTSVKKPPKLQRGKKRKRQVSSEDDDDDEDGETPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGADEHEDNSETIEKVLDIRLGKKGATGASTTVYATEANGNPSADFDPEKDEGEVHYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEEEIKQWLAKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSAAGHADFPANSRKTSSNDPEYLCKWMGLPYAECSWEDEALISKKFQHCIDSFNNRNNSKTIPTRDCKVLKQRPRFVALKKQPSYIGSENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLVVVPLSTLTSWQREFEVWAPEINVVVYIGDLMSRNMIREYEWIHSQSKRLKFNALITTYEILLKDKAVLGSISWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALSKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGIETLQSLIRSSGKLILLDKLLTRLRDRGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLDNNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEEEETELDERPQKDWDDIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSESDAETKRRLQRSSGSESETDDTDDEKRPKRRGRPRSVRKDTVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENPGETGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPADPEERKKYRLTCRVKAAHFDVDWGVEEDSRLLVGIYEHGYGNWELIKTDPELKLSDKILPVETDKKPQGKQLQTRVDYLLKLLKKDLEKKENMKDGEEGKLKKRKPRVKKENKAPKVKDEHGNELSPPRHSDNQSEEGEVKDDGLDKSPVKKKQKKKENKENKEKQTSSKKEKESDKEKKKTKEKKEKPKGGEAKSGSKGKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLTVQEQLEHTRNCLLKIGDRISECLKAYTDQDLIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKEDMASMPSMKKPFRPEPSGSSRDPAMSQSHVPHNPHSQKLHMPPSHAQQQMHGHPRESYGHPPKRHFSNTDRGEWQRDRKFSYSGNSNQMWGGERHHQYEQHWYKDHHYGDRRSRGDPHRSSGNYRPNNLSRKRPYEQYSSDRDHRGHRDYYDRHHHDSKRRRSDEFRPQNYHQQDFRRMSDHRPPMGYHGQGPSDHYRSFHTDKPGDYKQPLPPPHPSVSDPRSPPSQKSPHDSKSPLDHRSPLDRSLEQKNNPDYNWNIRKT", "length": 1838 }, "evidence": [ { "id": "A0A0G2KA92", "url": "https://omabrowser.org/oma/group/A0A0G2KA92/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PZM4-1", "protein_name": "Chromodomain-helicase-DNA-binding protein 2", "gene_name": "Chd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMRNKDKSQEEDSSLHSNASSRSASEEVSGSDSGSQSESEQGSEPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNVKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDEQEQGTSAESEAEQKKGKARRPVPRRTVPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGGDEQQDNSETIEKVLDSRLGKKGATGASTTVYAVEANGDPSDDFDTEREEGEVQYLIKWKGWSYIHSTWESEDSLQQQKVKGLKKLENFKKKEDEVKQWLGKVSPEDVEYFSCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGESLELRDYQLEGLNWLAHSWCKSNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKAPEDSERESGQEVLQSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSGRSNSNPFNKEELTAILKFGAEDLFKEIEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETDDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKESTSEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRVDYLLKLLRKGLEKKGTVASGEEAKLKKRKPRVKKENKAPRLKDEHGLEPASPRHSDNPSEEGEVKDDGLEKSPTKKKQKKKENKENKEKPVSSRKDREGDKERKKSKDKKEKVKGGDGKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLSVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDSLGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHPRDNYSHPNKRHFSNADRGDWQRERKFNYGGGNSAPWGGDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYEQYNSDRDHRGHRDYYDRHHHDSKRRRSDDFRPQNYHQQDFRRMSDHRPTMGYHGQGPSDHYRSFHTDKLGEYKQPMPSLHTALSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT", "length": 1827 }, "evidence": [ { "id": "47564634", "url": "http://www.informatics.jax.org/homology/47564634", "database": "MGI" }, { "id": "A0A0G2KA92", "url": "https://omabrowser.org/oma/group/A0A0G2KA92/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F4IV99-1", "protein_name": "Protein CHROMATIN REMODELING 5", "gene_name": "CHR5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAFFRNYSNDTVSHNVLDENEERQNAATFQSSPLNEDVDGTYSERGFDMNMDVQYQSDPEPGCSIRQPNETAVDNVADPVDSHYQSSTKRLGVTGRWGSTFWKDCQPMGQREGSDPAKDSQSGYKEAYHSEDNHSNDRSEKLDSENENDNENEEEDNEMNKHQSGQADVPADEMLSDEYYEQDEDNQSDHVHYKGYSNPTNSRSLPKAGSAVHSNSRTSRAIHKNIHYSDSNHDHNGDADMDYEEEEDEDDPEDADFEPYDAADDGGASKKHGQGWDVSDEDPESDEEIDLSDYEDDYGTKKPKVRQQSKGFRKSSAGLERKSFHVSSRQKRKTSYQDDDSEEDSENDNDEGFRSLARRGTTLRQNNGRSTNTIGQSSEVRSSTRSVRKVSYVESEDSEDIDDGKNRKNQKDDIEEEDADVIEKVLWHQLKGMGEDVQTNNKSTVPVLVSQLFDTEPDWNEMEFLIKWKGQSHLHCQWKTLSDLQNLSGFKKVLNYTKKVTEEIRYRTALSREEIEVNDVSKEMDLDIIKQNSQVERIIADRISKDGLGDVVPEYLVKWQGLSYAEATWEKDVDIAFAQVAIDEYKAREVSIAVQGKMVEQQRTKGKASLRKLDEQPEWLIGGTLRDYQLEGLNFLVNSWLNDTNVILADEMGLGKTVQSVSMLGFLQNTQQIPGPFLVVVPLSTLANWAKEFRKWLPGMNIIVYVGTRASREVCQQYEFYNEKKVGRPIKFNALLTTYEVVLKDKAVLSKIKWIYLMVDEAHRLKNSEAQLYTALLEFSTKNKLLITGTPLQNSVEELWALLHFLDPGKFKNKDEFVENYKNLSSFNESELANLHLELRPHILRRVIKDVEKSLPPKIERILRVEMSPLQKQYYKWILERNFHDLNKGVRGNQVSLLNIVVELKKCCNHPFLFESADHGYGGDINDNSKLDKIILSSGKLVILDKLLVRLRETKHRVLIFSQMVRMLDILAEYLSLRGFQFQRLDGSTKAELRQQAMDHFNAPASDDFCFLLSTRAGGLGINLATADTVVIFDSDWNPQNDLQAMSRAHRIGQQEVVNIYRFVTSKSVEEEILERAKRKMVLDHLVIQKLNAEGRLEKRETKKGSNFDKNELSAILRFGAEELFKEDKNDEESKKRLLSMDIDEILERAEQVEEKHTDETEHELLGAFKVANFCNAEDDGSFWSRWIKPDSVVTAEEALAPRAARNTKSYVDPSHPDRTSKRKKKGSEPPEHTERSQKRRKTEYFVPSTPLLEGTSAQVRGWSYGNLPKRDAQRFYRTVMKFGNHNQMACIAEEVGGVVEAAPEEAQVELFDALIDGCKESVETGNFEPKGPVLDFFGVPVKANELLKRVQGLQLLSKRISRYNDPISQFRVLSYLKPSNWSKGCGWNQIDDARLLLGILYHGFGNWEKIRLDESLGLTKKIAPVELQHHETFLPRAPNLKERATALLEMELAAAGGKNTNAKASRKNSKKVKDNLINQFKAPARDRRGKSGPANVSLLSTKDGPRKTQKAEPLVKEEGEMSDDGEVYEQFKEQKWMEWCEDVLADEIKTLGRLQRLQTTSADLPKEKVLFKIRRYLEILGRRIDAIVLEHEEDLYKQDRMTMRLWNYVSTFSNLSGDRLNQIYSKLKQEKEEEEGVGPSHLNGSRNFQRQQKFKTAGNSQGSQQVHKGIDTAKFEAWKRRRRTENDVQTERPTITNSNSLGILGPGPLDRSHRARQTGFPPR", "length": 1724 }, "evidence": [ { "id": "A0A0G2KA92", "url": "https://omabrowser.org/oma/group/A0A0G2KA92/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O14647-1", "protein_name": "Chromodomain-helicase-DNA-binding protein 2", "gene_name": "CHD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1828 }, "evidence": [ { "id": "47564634", "url": "http://www.informatics.jax.org/homology/47564634", "database": "MGI" }, { "id": "A0A0G2KA92", "url": "https://omabrowser.org/oma/group/A0A0G2KA92/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "nucleosome organization", "id": "GO:0034728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034728", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "hematopoietic stem cell differentiation", "id": "GO:0060218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060218", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA92", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1208, "end_pos": 1210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1705, "end_pos": 1707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + H(+) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "D3ZD32-1", "D4A523-1", "Q3MHU3-1", "F1M298-1", "Q5RJZ1-1", "P60123-1", "Q793F9-1", "F1LPQ2-1", "G3V681-1", "F1LNJ2-1", "D4A2Z8-1", "Q5RKI1-1", "P70486-1", "Q66HG7-1", "Q99PT0-1", "D3ZG52-1", "Q5U216-1", "Q62780-1", "Q641Y8-1", "Q5BJS0-1", "Q63413-1", "Q64060-1", "Q9JIX5-1", "P06761-1", "Q6GX84-1", "Q5XI69-1", "Q9QUL6-1", "Q1HG60-1", "Q3B8Q2-1", "P46462-1", "D3ZA12-1", "D3Z9Z9-1", "Q68G38-1", "Q9QY16-1", "A0A8I5ZZZ0-1", "A0A0G2K0H9-1", "Q62724-1", "Q5EBA1-1", "Q3B8Q1-1", "Q9EQN5-1", "F1M9L4-1", "F1M5F3-1", "D3ZFP4-1", "F1MA70-1", "D3ZBY5-1", "D3ZVK1-1", "D3ZX56-1", "B1H269-1", "Q9WTT2-1", "G3V8T5-1", "Q8CG07-1", "B2GUX3-1", "P08289-1", "D3ZP96-1", "D3ZHW0-1", "Q5XIR6-1", "A0A8I6AFW4-1", "Q5XI46-1", "A0A0G2KA92-1", "D4AAG9-1", "A0A096MJV7-1", "A0A0G2JTM6-1", "A0A8I5ZKV9-1", "A0A8I5ZKH1-1", "D3ZD46-1", "A0A8I6GIY0-1", "E9PU01-1", "A0A8I6ABZ7-1", "D3ZAP7-1", "D4A321-1", "A0A0G2K283-1", "Q6MG13-1", "P62738-1", "P63259-1", "P68035-1", "P68136-1", "P60711-1", "P63269-1", "P56536-1", "P54777-1", "D3ZSV6-1", "D3ZUC2-1", "G3V6W5-1", "D3ZD97-1", "D3ZEG9-1", "A6KAR2-1", "P63018-1", "P82995-1", "D4ADT5-1", "D4A6Q6-1", "A0A8I5ZMZ5-1", "A0A8I6GIN4-1", "A6KSS8-1", "D4A2B7-1", "A0A8I6AK63-1", "A0A0G2K4S4-1", "F1LTR3-1", "F1LWY1-1", "D4A1R0-1", "P97687-1", "Q9JIL8-1", "Q925S8-1", "Q6AYJ1-1", "D4ACP5-1", "Q641Z7-1", "Q5EB68-1", "D3ZQW1-1", "Q4G005-1", "M0RCB1-1", "A0A8I6AGW3-1", "A0A8I6AQL9-1", "Q5BKE0-1", "F1LTH9-1", "P34158-1", "Q7TT47-1", "F1M3J4-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A096MJV7", "gene_name": "Chd9", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A096MJV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A096MJV7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A096MJV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A096MJV7" } ] } ] }, { "uniprot_ac": "A0A0G2JTM6", "gene_name": "Dhx35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A0G2JTM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JTM6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A0G2JTM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2JTM6" } ] } ] }, { "uniprot_ac": "A0A0G2K0H9", "gene_name": "Ruvbl1-ps1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A0G2K0H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K0H9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A0G2K0H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K0H9" } ] } ] }, { "uniprot_ac": "A0A0G2K283", "gene_name": "Dhx8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A0G2K283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K283" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A0G2K283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K283" } ] } ] }, { "uniprot_ac": "A0A0G2K4S4", "gene_name": "Ddx51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A0G2K4S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K4S4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A0G2K4S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K4S4" } ] } ] }, { "uniprot_ac": "A0A0G2KA92", "gene_name": "Chd2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A0G2KA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A0G2KA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2KA92" } ] } ] }, { "uniprot_ac": "A0A8I5ZKH1", "gene_name": "Ythdc2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I5ZKH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKH1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8I5ZKH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKH1" } ] } ] }, { "uniprot_ac": "A0A8I5ZKV9", "gene_name": "Ddx5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I5ZKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKV9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8I5ZKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZKV9" } ] } ] }, { "uniprot_ac": "A0A8I5ZMZ5", "gene_name": "LOC100912568", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I5ZMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMZ5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8I5ZMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZMZ5" } ] } ] }, { "uniprot_ac": "A0A8I5ZZZ0", "gene_name": "Ddx31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I5ZZZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZZ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8I5ZZZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZZZ0" } ] } ] }, { "uniprot_ac": "A0A8I6ABZ7", "gene_name": "Dhx9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I6ABZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ABZ7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8I6ABZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6ABZ7" } ] } ] }, { "uniprot_ac": "A0A8I6AFW4", "gene_name": "Ddx24", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I6AFW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AFW4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8I6AFW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AFW4" } ] } ] }, { "uniprot_ac": "A0A8I6AGW3", "gene_name": "Fignl2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8I6AGW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AGW3" } ] } ] }, { "uniprot_ac": "A0A8I6AK63", "gene_name": "ENSRNOG00000069014", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I6AK63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AK63" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8I6AK63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AK63" } ] } ] }, { "uniprot_ac": "A0A8I6AQL9", "gene_name": "Hspa8-ps23", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I6AQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AQL9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8I6AQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6AQL9" } ] } ] }, { "uniprot_ac": "A0A8I6GIN4", "gene_name": "AC129365.1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I6GIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GIN4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8I6GIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GIN4" } ] } ] }, { "uniprot_ac": "A0A8I6GIY0", "gene_name": "Chd3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A0A8I6GIY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GIY0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8I6GIY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I6GIY0" } ] } ] }, { "uniprot_ac": "A6KAR2", "gene_name": "Ddx41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A6KAR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KAR2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A6KAR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KAR2" } ] } ] }, { "uniprot_ac": "A6KSS8", "gene_name": "Mcm7", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "A6KSS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KSS8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6KSS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A6KSS8" } ] } ] }, { "uniprot_ac": "B1H269", "gene_name": "Ddx27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "B1H269", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1H269" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "B1H269", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1H269" } ] } ] }, { "uniprot_ac": "B2GUX3", "gene_name": "Mcm5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "B2GUX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUX3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "B2GUX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2GUX3" } ] } ] }, { "uniprot_ac": "D3Z9Z9", "gene_name": "Smarcad1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3Z9Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z9Z9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3Z9Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z9Z9" } ] } ] }, { "uniprot_ac": "D3ZA12", "gene_name": "Chd6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZA12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZA12" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZA12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZA12" } ] } ] }, { "uniprot_ac": "D3ZAP7", "gene_name": "Chd7", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZAP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZAP7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZAP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZAP7" } ] } ] }, { "uniprot_ac": "D3ZBY5", "gene_name": "Ddx10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZBY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBY5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZBY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZBY5" } ] } ] }, { "uniprot_ac": "D3ZD32", "gene_name": "Chd5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD32" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD32" } ] } ] }, { "uniprot_ac": "D3ZD46", "gene_name": "Dhx58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZD46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD46" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZD46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD46" } ] } ] }, { "uniprot_ac": "D3ZD97", "gene_name": "Dhx15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZD97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD97" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZD97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZD97" } ] } ] }, { "uniprot_ac": "D3ZEG9", "gene_name": "Ercc2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZEG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEG9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZEG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZEG9" } ] } ] }, { "uniprot_ac": "D3ZFP4", "gene_name": "Mcm3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZFP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFP4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZFP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZFP4" } ] } ] }, { "uniprot_ac": "D3ZG52", "gene_name": "Dna2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "D3ZG52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG52" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZG52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG52" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZG52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZG52" } ] } ] }, { "uniprot_ac": "D3ZHW0", "gene_name": "Dhx29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZHW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHW0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZHW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZHW0" } ] } ] }, { "uniprot_ac": "D3ZP96", "gene_name": "Mcm2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZP96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZP96" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZP96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZP96" } ] } ] }, { "uniprot_ac": "D3ZQW1", "gene_name": "Blm", "activity": [ { "ec_number": "5.6.2.4", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.", "evidence": [ { "id": "D3ZQW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQW1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "D3ZQW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZQW1" } ] } ] }, { "uniprot_ac": "D3ZSV6", "gene_name": "Dhx33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZSV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSV6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZSV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZSV6" } ] } ] }, { "uniprot_ac": "D3ZUC2", "gene_name": "Mov10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZUC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZUC2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZUC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZUC2" } ] } ] }, { "uniprot_ac": "D3ZVK1", "gene_name": "Mcm8", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZVK1" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D3ZVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZVK1" } ] } ] }, { "uniprot_ac": "D3ZX56", "gene_name": "Ddx55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3ZX56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZX56" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3ZX56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3ZX56" } ] } ] }, { "uniprot_ac": "D4A1R0", "gene_name": "Dhx37", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A1R0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D4A1R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A1R0" } ] } ] }, { "uniprot_ac": "D4A2B7", "gene_name": "Afg2b", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A2B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2B7" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "D4A2B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2B7" } ] } ] }, { "uniprot_ac": "D4A2Z8", "gene_name": "Dhx36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A2Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2Z8" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A2Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2Z8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D4A2Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2Z8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D4A2Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A2Z8" } ] } ] }, { "uniprot_ac": "D4A321", "gene_name": "Dhx38", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4A321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A321" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D4A321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A321" } ] } ] }, { "uniprot_ac": "D4A523", "gene_name": "Nlrp3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "D4A523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A523" } ] } ] }, { "uniprot_ac": "D4A6Q6", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "D4A6Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A6Q6" } ] } ] }, { "uniprot_ac": "D4AAG9", "gene_name": "Chd1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4AAG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AAG9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "D4AAG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4AAG9" } ] } ] }, { "uniprot_ac": "D4ACP5", "gene_name": "Recql5", "activity": [ { "ec_number": "5.6.2.4", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.", "evidence": [ { "id": "D4ACP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACP5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "D4ACP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ACP5" } ] } ] }, { "uniprot_ac": "D4ADT5", "gene_name": "Rig1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D4ADT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ADT5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D4ADT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4ADT5" } ] } ] }, { "uniprot_ac": "E9PU01", "gene_name": "Chd4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "E9PU01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PU01" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E9PU01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PU01" } ] } ] }, { "uniprot_ac": "F1LNJ2", "gene_name": "Snrnp200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1LNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1LNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LNJ2" } ] } ] }, { "uniprot_ac": "F1LPQ2", "gene_name": "Ascc3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1LPQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LPQ2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1LPQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LPQ2" } ] } ] }, { "uniprot_ac": "F1LTH9", "gene_name": "Wrn", "activity": [ { "ec_number": "5.6.2.4", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.", "evidence": [ { "id": "F1LTH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTH9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1LTH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTH9" } ] } ] }, { "uniprot_ac": "F1LTR3", "gene_name": "Tdrd12", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1LTR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTR3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1LTR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LTR3" } ] } ] }, { "uniprot_ac": "F1LWY1", "gene_name": "Hfm1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1LWY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWY1" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1LWY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1LWY1" } ] } ] }, { "uniprot_ac": "F1M298", "gene_name": "Fbh1", "activity": [ { "ec_number": "5.6.2.4", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.", "evidence": [ { "id": "F1M298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M298" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1M298", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M298" } ] } ] }, { "uniprot_ac": "F1M3J4", "gene_name": "Abcc4", "activity": [ { "ec_number": "7.6.2.2", "activity": "ATP + daunorubicin(in) + H2O = ADP + daunorubicin(out) + H(+) + phosphate.", "evidence": [ { "id": "F1M3J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M3J4" } ] }, { "ec_number": "7.6.2.-", "activity": "", "evidence": [ { "id": "F1M3J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M3J4" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = ADP + an S-substituted glutathione(out) + H(+) + phosphate.", "evidence": [ { "id": "F1M3J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M3J4" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "F1M3J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M3J4" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "F1M3J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M3J4" } ] }, { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1M3J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M3J4" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1M3J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M3J4" } ] } ] }, { "uniprot_ac": "F1M5F3", "gene_name": "Mcm9", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "F1M5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M5F3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1M5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M5F3" } ] } ] }, { "uniprot_ac": "F1M9L4", "gene_name": "Atp13a4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1M9L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M9L4" } ] } ] }, { "uniprot_ac": "F1MA70", "gene_name": "Atp13a5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1MA70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1MA70" } ] } ] }, { "uniprot_ac": "G3V681", "gene_name": "Mcm4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "G3V681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V681" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "G3V681", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V681" } ] } ] }, { "uniprot_ac": "G3V6W5", "gene_name": "Ifih1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "G3V6W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6W5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3V6W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V6W5" } ] } ] }, { "uniprot_ac": "G3V8T5", "gene_name": "Ruvbl2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "G3V8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V8T5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "G3V8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3V8T5" } ] } ] }, { "uniprot_ac": "M0RCB1", "gene_name": "Hsc70-ps1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "M0RCB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RCB1" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "M0RCB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/M0RCB1" } ] } ] }, { "uniprot_ac": "P06761", "gene_name": "Hspa5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P06761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06761" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P06761", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06761" } ] } ] }, { "uniprot_ac": "P08289", "gene_name": "Alpl", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P08289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08289" } ] }, { "ec_number": "3.9.1.1", "activity": "H2O + N-phosphocreatine = creatine + phosphate.", "evidence": [ { "id": "P08289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08289" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P08289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08289" } ] } ] }, { "uniprot_ac": "P34158", "gene_name": "Cftr", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P34158", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34158" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "P34158", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P34158" } ] } ] }, { "uniprot_ac": "P46462", "gene_name": "Vcp", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P46462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46462" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "P46462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46462" } ] } ] }, { "uniprot_ac": "P54777", "gene_name": "Pex6", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P54777", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54777" } ] } ] }, { "uniprot_ac": "P56536", "gene_name": "Kif5c", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P56536", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P56536" } ] } ] }, { "uniprot_ac": "P60123", "gene_name": "Ruvbl1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P60123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60123" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P60123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60123" } ] } ] }, { "uniprot_ac": "P60711", "gene_name": "Actb", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60711", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P60711" } ] } ] }, { "uniprot_ac": "P62738", "gene_name": "Acta2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62738" } ] } ] }, { "uniprot_ac": "P63018", "gene_name": "Hspa8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P63018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63018" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P63018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63018" } ] } ] }, { "uniprot_ac": "P63259", "gene_name": "Actg1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63259", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63259" } ] } ] }, { "uniprot_ac": "P63269", "gene_name": "Actg2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63269", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63269" } ] } ] }, { "uniprot_ac": "P68035", "gene_name": "Actc1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68035" } ] } ] }, { "uniprot_ac": "P68136", "gene_name": "Acta1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P68136" } ] } ] }, { "uniprot_ac": "P70486", "gene_name": "Atrx", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P70486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70486" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "P70486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70486" } ] } ] }, { "uniprot_ac": "P82995", "gene_name": "Hsp90aa1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P82995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82995" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P82995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P82995" } ] } ] }, { "uniprot_ac": "P97687", "gene_name": "Entpd1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 H(+) + 2 phosphate.", "evidence": [ { "id": "P97687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97687" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "P97687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P97687" } ] } ] }, { "uniprot_ac": "Q1HG60", "gene_name": "Pif1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q1HG60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1HG60" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q1HG60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1HG60" } ] } ] }, { "uniprot_ac": "Q3B8Q1", "gene_name": "Ddx21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q3B8Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3B8Q1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q3B8Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3B8Q1" } ] } ] }, { "uniprot_ac": "Q3B8Q2", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q3B8Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3B8Q2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q3B8Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3B8Q2" } ] } ] }, { "uniprot_ac": "Q3MHU3", "gene_name": "Tdrd9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q3MHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MHU3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q3MHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3MHU3" } ] } ] }, { "uniprot_ac": "Q4G005", "gene_name": "Ercc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.", "evidence": [ { "id": "Q4G005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4G005" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "Q4G005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q4G005" } ] } ] }, { "uniprot_ac": "Q5BJS0", "gene_name": "Dhx30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q5BJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5BJS0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5BJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5BJS0" } ] } ] }, { "uniprot_ac": "Q5BKE0", 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