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"MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPVGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGSDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHHQRLSGNVSGSFTLMRDERGLPSMNNLYSPYKEMPSMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGHTQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLGTGGSSSTSGTCTKA", "length": 505, "header": "tr|A0A0G2KA21-1|A0A0G2KA21_RAT Isoform 1 of One cut domain family member OS=Rattus norvegicus OX=10116 GN=Onecut2 PE=3 SV=2 CANONICAL=A0A0G2KA21-1" }, "locus": { "chromosome": "18", "start_pos": 57878970, "end_pos": 57832111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000078378.2", "url": "https://www.ensembl.org/id/ENSRNOT00000078378.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000075225.2", "url": "https://www.ensembl.org/id/ENSRNOP00000075225.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M7Z3-1", "protein_name": "One cut domain family member", "gene_name": "ONECUT2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGGPGHEPELLASPSPHHAGRGAAGSLRGPPPPPPPPPPPTAHQELGTAAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHQQRLSGNVSGSFTLLRDERGLPTMNNLYSPYKEMPGMGQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGPDKMLSPNFDAHHTAMLTRGDQHLSRGLGTPPAAMMSHLNGLHHPGHAQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGASPAGSDGVWLQLHPRPRPVDAPRSGPLEGVQRSRGAELPVGACKRKEQEPSKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLSAGGASSTSGTCTKA", "length": 557 }, "evidence": [ { "id": "A0A0G2KA21", "url": "https://omabrowser.org/oma/group/A0A0G2KA21/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95948-1", "protein_name": "One cut domain family member 2", "gene_name": "ONECUT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHQRLSGNVSGSFTLMRDERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGHTQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLSTGGSSSTSSTCTKA", "length": 504 }, "evidence": [ { "id": "A0A0G2KA21", "url": "https://omabrowser.org/oma/group/A0A0G2KA21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6XBJ3-1", "protein_name": "One cut domain family member 2", "gene_name": "Onecut2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPVGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGSDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHHQRLSGNVSGSFTLMRDERGLPSMNNLYSPYKEMPSMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGHTQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLGTGGSSSTSSTCTKA", "length": 505 }, "evidence": [ { "id": "A0A0G2KA21", "url": "https://omabrowser.org/oma/group/A0A0G2KA21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 15, "go_terms": [ { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "positive regulation of mesenchymal stem cell migration", "id": "GO:1905322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905322", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "pancreas development", "id": "GO:0031016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031016", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "regulation of cell-matrix adhesion", "id": "GO:0001952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001952", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "epithelial cell development", "id": "GO:0002064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002064", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "cell fate commitment", "id": "GO:0045165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "peripheral nervous system neuron development", "id": "GO:0048935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048935", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" }, { "name": "mesenchymal stem cell migration", "id": "GO:1905319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905319", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KA21", "url": "https://www.uniprot.org/uniprot/A0A0G2KA21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": 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