{
    "uniprot_canonical_ac": "A0A0G2JXG2-1",
    "uniprot_ac": "A0A0G2JXG2",
    "uniprot_id": "A0A0G2JXG2_RAT",
    "mass": {
        "chemical_mass": 121372.0,
        "monoisotopic_mass": 121372.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Kdm4b",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2",
            "id": "A0A0G2JXG2"
        }
    ],
    "protein_names": [
        {
            "name": "[histone H3]-trimethyl-L-lysine(9) demethylase",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2JXG2/entry#names_and_taxonomy",
            "id": "A0A0G2JXG2"
        },
        {
            "name": "1.14.11.66",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2JXG2/entry#names_and_taxonomy",
            "id": "A0A0G2JXG2"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0050902",
            "recommended_name": {
                "id": "DOID:0050902",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050902",
                "name": "medulloblastoma",
                "description": "An infratentorial cancer that is located_in the lower part of the brain and is a type of primitive neuroectodermal tumor."
            },
            "synonyms": [
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "CNS PNET",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "CPNET",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "brain medulloblastoma",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "infratentorial primitive neuroectodermal tumor",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "localized primitive neuroectodermal tumor",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "Medulloblastoma, histologically defined",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma",
                    "description": "A malignant, invasive embryonal neoplasm arising from the cerebellum. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity."
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "brain medulloblastoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "cerebellar medulloblastoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "cerebellum embryonal neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, autosomal recessive, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, desmoplastic, autosomal recessive, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, malignant",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastomas",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "CNS PNET",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "CPNET",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "MDB",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "infratentorial primitive neuroectodermal tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "infratentorial primitive neuroectodermal tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "localised primitive neuroectodermal tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "localized primitive neuroectodermal tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma with extensive nodularity",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, desmoplastic",
                    "description": ""
                },
                {
                    "id": "MIM:155255",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/155255",
                    "name": "Medulloblastoma",
                    "description": "Medulloblastoma"
                }
            ],
            "evidence": [
                {
                    "id": "0050902",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050902"
                }
            ]
        },
        {
            "disease_id": "DOID:0060307",
            "recommended_name": {
                "id": "DOID:0060307",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060307",
                "name": "autosomal dominant intellectual developmental disorder",
                "description": "A intellectual disability characterized by an autosomal dominant inheritance pattern."
            },
            "synonyms": [
                {
                    "id": "DOID:0060307",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060307",
                    "name": "autosomal dominant mental retardation",
                    "description": ""
                },
                {
                    "id": "DOID:0060307",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060307",
                    "name": "autosomal dominant non-syndromic mental retardation",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "intellectual disability, autosomal dominant 1",
                    "description": "An autosomal dominant condition caused by mutation(s) in the MBD5 gene, encoding methyl-CpG-binding domain protein 5. It is characterized by severe developmental and cognitive delay, short stature, craniofacial dysmorphism, and seizures."
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "MBD5 autosomal dominant non-syndromic intellectual disability",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "MRD1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "autosomal dominant intellectual disability 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "autosomal dominant mental retardation 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "autosomal dominant non-syndromic intellectual disability caused by mutation in MBD5",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "intellectual disability, autosomal dominant 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "intellectual disability, autosomal dominant type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "mental retardation, autosomal dominant type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "autosomal dominant non-syndromic intellectual disability 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "chromosome 2Q23.1 deletion syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007974",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007974",
                    "name": "mental retardation, autosomal dominant 1",
                    "description": ""
                },
                {
                    "id": "MIM:156200",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/156200",
                    "name": "Intellectual developmental disorder, autosomal dominant 1",
                    "description": "Intellectual developmental disorder, autosomal dominant 1"
                }
            ],
            "evidence": [
                {
                    "id": "0060307",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060307"
                }
            ]
        },
        {
            "disease_id": "DOID:10283",
            "recommended_name": {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10283",
                "name": "prostate cancer",
                "description": "A male reproductive organ cancer that is located_in the prostate."
            },
            "synonyms": [
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "NGP - new growth of prostate",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "hereditary prostate cancer",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "malignant tumor of the prostate",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostate cancer, familial",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostate neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostatic cancer",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "prostatic neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:10283",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10283",
                    "name": "tumor of the prostate",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "prostate cancer, hereditary, type 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012597",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                    "name": "HPC9",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, 12",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene."
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "EHBP1 familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "familial prostate cancer caused by mutation in EHBP1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "prostate cancer, hereditary, type 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012741",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                    "name": "HPC12",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "prostate cancer, hereditary, type 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012244",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                    "name": "HPC5",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, hereditary, type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "prostate cancer, susceptibility to, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012093",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                    "name": "HPC3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, susceptibility to, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "HPC4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012094",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                    "name": "prostate cancer, hereditary, on chromosome 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, 13",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene."
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "MSMB familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "familial prostate cancer caused by mutation in MSMB",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "prostate cancer, hereditary, type 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0012758",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                    "name": "HPC13",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, hereditary, type 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "HPC8",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "predisposing for prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0011270",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                    "name": "prostate cancer, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, hereditary, type 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "HPC6",
                    "description": ""
                },
                {
                    "id": "MONDO:0012300",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                    "name": "prostate cancer, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "prostate cancer, hereditary, 10",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "HPC10",
                    "description": ""
                },
                {
                    "id": "MONDO:0012620",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                    "name": "prostate cancer, hereditary, 10",
                    "description": ""
                },
                {
                    "id": "MONDO:0700275",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0700275",
                    "name": "prostate cancer, hereditary",
                    "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents."
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer, hereditary, 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "HPC7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer, hereditary, 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012470",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                    "name": "prostate cancer aggressiveness",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, 1",
                    "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene."
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "RNASEL familial prostate cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "familial prostate cancer caused by mutation in RNASEL",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "prostate cancer, hereditary, type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "HPC1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011098",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                    "name": "Prca1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "prostate cancer, hereditary, 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "HPC11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012768",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                    "name": "prostate cancer, hereditary, 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "prostate cancer, hereditary, 14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "HPC14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012769",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                    "name": "prostate cancer, hereditary, 14",
                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "prostate cancer, hereditary, 15",
                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "HPC15",
                    "description": ""
                },
                {
                    "id": "MONDO:0012770",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                    "name": "prostate cancer, hereditary, 15",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "prostate cancer, hereditary, X-linked 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "HPCX1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "prostate cancer, hereditary, X-linked 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010257",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                    "name": "prostate cancer susceptibility, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010405",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                    "name": "prostate cancer, hereditary, X-linked 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0010405",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                    "name": "HPCX2",
                    "description": ""
                },
                {
                    "id": "MONDO:0010405",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                    "name": "prostate cancer, hereditary, X-linked 2",
                    "description": ""
                },
                {
                    "id": "MIM:611868",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611868",
                    "name": "Prostate cancer, hereditary, 12",
                    "description": "Prostate cancer, hereditary, 12"
                },
                {
                    "id": "MIM:611928",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611928",
                    "name": "Prostate cancer, hereditary, 13",
                    "description": "Prostate cancer, hereditary, 13"
                },
                {
                    "id": "MIM:176807",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/176807",
                    "name": "Prostate cancer",
                    "description": "Prostate cancer"
                },
                {
                    "id": "MIM:601518",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/601518",
                    "name": "Prostate cancer, hereditary, 1",
                    "description": "Prostate cancer, hereditary, 1"
                },
                {
                    "id": "MIM:611955",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/611955",
                    "name": "Prostate cancer, hereditary, 11",
                    "description": "Prostate cancer, hereditary, 11"
                }
            ],
            "evidence": [
                {
                    "id": "10283",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10283"
                }
            ]
        },
        {
            "disease_id": "DOID:10534",
            "recommended_name": {
                "id": "DOID:10534",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10534",
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                "description": "A gastrointestinal system cancer that is located_in the stomach."
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            "synonyms": [
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10534",
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                },
                {
                    "id": "DOID:10534",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10534",
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                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric cancer",
                    "description": "A primary or metastatic malignant neoplasm involving the stomach."
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "Ca lesser curvature - stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "cancer of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric cancer risk after h. pylori infection",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "gastric cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant gastric neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant gastric tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant gastric tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant neoplasm of lesser curve of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant neoplasm of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant neoplasm of the stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant stomach neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of body of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of greater curve of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of lesser curve of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumor of the stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of body of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of greater curve of stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of lesser curve of stomach",
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                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of stomach",
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                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                    "name": "malignant tumour of the stomach",
                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
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                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
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                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
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                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
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                    "description": ""
                },
                {
                    "id": "MONDO:0001056",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001056",
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                    "description": ""
                },
                {
                    "id": "MIM:613659",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/613659",
                    "name": "Gastric cancer",
                    "description": "Gastric cancer"
                }
            ],
            "evidence": [
                {
                    "id": "10534",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10534"
                }
            ]
        },
        {
            "disease_id": "DOID:11054",
            "recommended_name": {
                "id": "DOID:11054",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:11054",
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                },
                {
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                },
                {
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                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "urinary bladder cancer",
                    "description": "A primary or metastatic malignant neoplasm involving the bladder."
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "tumor of the bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
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                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "bladder cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "cancer of urinary bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
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                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant bladder tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant bladder tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant neoplasm of bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant neoplasm of the bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant neoplasm of the urinary bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant neoplasm of urinary bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant neoplasm, bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant neoplasm, urinary bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant tumor of bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant tumor of the bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant tumor of the urinary bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant tumor of urinary bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant tumor, urinary bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant tumour of bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant tumour of the bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant tumour of the urinary bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant tumour of urinary bladder",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant urinary bladder neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant urinary bladder tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "malignant urinary bladder tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "urinary bladder cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "urinary bladder malignant neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "urinary bladder malignant tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0001187",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0001187",
                    "name": "urinary bladder malignant tumour",
                    "description": ""
                },
                {
                    "id": "MIM:109800",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/109800",
                    "name": "Bladder cancer",
                    "description": "Bladder cancer"
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            ],
            "evidence": [
                {
                    "id": "11054",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:11054"
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            ]
        },
        {
            "disease_id": "DOID:1324",
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                "resource": "Disease Ontology",
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            "synonyms": [
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                {
                    "id": "MONDO:0012159",
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                {
                    "id": "MONDO:0012159",
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                {
                    "id": "MONDO:0012159",
                    "resource": "MONDO",
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                    "id": "MONDO:0012942",
                    "resource": "MONDO",
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                    "description": ""
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                {
                    "id": "MONDO:0012942",
                    "resource": "MONDO",
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                {
                    "id": "MONDO:0012942",
                    "resource": "MONDO",
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                {
                    "id": "MONDO:0012942",
                    "resource": "MONDO",
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                    "name": "adenocarcinoma of lung, susceptibility to",
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                    "id": "MONDO:0012955",
                    "resource": "MONDO",
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                {
                    "id": "MONDO:0012955",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012955",
                    "name": "LNCR4",
                    "description": ""
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                {
                    "id": "MONDO:0012955",
                    "resource": "MONDO",
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                    "name": "lung cancer susceptibility 4",
                    "description": ""
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                {
                    "id": "MONDO:0013631",
                    "resource": "MONDO",
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                    "name": "lung cancer susceptibility 5",
                    "description": ""
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                {
                    "id": "MONDO:0013631",
                    "resource": "MONDO",
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                    "name": "LNCR5",
                    "description": ""
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                {
                    "id": "MONDO:0013631",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                    "name": "lung cancer susceptibility 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "lung cancer",
                    "description": "A malignant neoplasm involving the lung."
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation",
                    "description": ""
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "adenocarcinoma of lung, somatic",
                    "description": ""
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "cancer of lung",
                    "description": ""
                },
                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "lung cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "lung cancer, protection against, autosomal dominant, somatic mutation",
                    "description": ""
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "lung cancer, resistance to, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "lung cancer, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "malignant lung neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "malignant lung tumor",
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "malignant lung tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "malignant neoplasm of lung",
                    "description": ""
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "malignant neoplasm of the lung",
                    "description": ""
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
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                    "name": "malignant tumor of lung",
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
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                    "name": "malignant tumor of the lung",
                    "description": ""
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                    "name": "malignant tumour of lung",
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
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                    "id": "MONDO:0008903",
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                    "id": "MONDO:0008903",
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                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
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                    "name": "alveolar cell carcinoma",
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                },
                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
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                    "name": "lung cancer, protection against",
                    "description": ""
                },
                {
                    "id": "MONDO:0008903",
                    "resource": "MONDO",
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                {
                    "id": "MIM:211980",
                    "resource": "MIM",
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                    "name": "Lung cancer",
                    "description": "Lung cancer"
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            ],
            "evidence": [
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                    "id": "1324",
                    "database": "Alliance of Genome Resources",
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                {
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                {
                    "id": "DOID:1612",
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                {
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                    "resource": "Disease Ontology",
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                {
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                    "resource": "MONDO",
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                {
                    "id": "MONDO:0016419",
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                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
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                    "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
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                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation",
                    "description": ""
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                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, lobular, somatic",
                    "description": ""
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                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0016419",
                    "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation",
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                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
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                    "name": "breast cancer, protection against, autosomal dominant, somatic mutation",
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                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
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                    "description": ""
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                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
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                    "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation",
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                    "id": "MONDO:0016419",
                    "resource": "MONDO",
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                    "id": "MONDO:0016419",
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                    "id": "MONDO:0016419",
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                    "id": "MONDO:0016419",
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                    "id": "MONDO:0016419",
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                {
                    "id": "MONDO:0016419",
                    "resource": "MONDO",
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                {
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        {
            "disease_id": "DOID:9256",
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                {
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                {
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                {
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                {
                    "id": "MONDO:0005575",
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                    "url": "https://monarchinitiative.org/disease/MONDO:0005575",
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                {
                    "id": "MONDO:0005575",
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                {
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                },
                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
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                    "name": "colorectal cancer with chromosomal instability, somatic",
                    "description": ""
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                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
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                    "description": ""
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                {
                    "id": "MONDO:0005575",
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                {
                    "id": "MONDO:0005575",
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                    "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation",
                    "description": ""
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                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
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                    "name": "colorectum cancer",
                    "description": ""
                },
                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                    "name": "malignant colorectal neoplasm",
                    "description": ""
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                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                    "name": "malignant colorectal tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
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                    "name": "malignant colorectal tumour",
                    "description": ""
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                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
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                    "name": "malignant colorectum neoplasm",
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                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                    "name": "malignant large bowel neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                    "name": "malignant large bowel tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                    "name": "malignant large bowel tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0005575",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                    "name": "malignant large intestine neoplasm",
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                },
                {
                    "id": "MONDO:0005575",
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            "url": "https://www.uniprot.org/uniprotkb/A0A0G2JXG2/entry#A0A8I5ZWQ3-1",
            "sequence": {
                "sequence": "MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRSILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSLKAKLLRRQISVKESRPWRKAEEERRPSLERRREPTRRPGPASHRRRSQPKKSKPEDSRSPGEATAGVAGLDEARGCSRRETMPEEEEEEELSPSQGHEAEGVEEDGRGKPRPTKARSKKKTPSLLSPPLLSAPPALFPAEEVLRLPPQPKSPGPAMGPMAAEGGPPPTALNVVPPGVPGEETEVRPRPIIPMLYVLPRANSSDGDREHAAHPQLAPMELGPEEEDQAQAGDSQGTTSFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEAFPFSGEDDGSDPEALRSLLSLQWKSKAASFQAERKLNAAAALSEPYCAVCTLFYPYSQSVQTEREVLATPGDSAVQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCVYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRASGAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRADIFTLEEELPKRVRSRLVSVLGVSIWGIEDACL",
                "length": 1055,
                "header": "tr|A0A8I5ZWQ3-1|A0A8I5ZWQ3_RAT Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(9) demethylase  OS=Rattus norvegicus OX=10116 GN=Kdm4b PE=3 SV=1 CANONICAL=A0A0G2JXG2-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 1235049,
                "end_pos": 1181954,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000108055.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000108055.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000083814.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000083814.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6GK41-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2JXG2/entry#A0A8I6GK41-1",
            "sequence": {
                "sequence": "MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRSILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSLKAKLLRRQISVKESRPWRKAEEERRREPTRRPGPASHRRRSQPKKSKPEDSRSPGEATAGVAGLDEARGCSRRETMPEEEEEEELSPSQGHEAEGVEEDGRGKPRPTKARSKKKTPSLLSPPLLSAPPALFPAEEVLRLPPQPKSPGPAMGPMAAEGGPPPTALNVVPPGVPGEETEVRPRPIIPMLYVLPRANSSDGDREHAAHPQLAPMELGPEEEDQAQAGDSQLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEAFPFSGEDDGSDPEALRSLLSLQWKSKAASFQAERKLNAAAALSEPYCAVCTLFYPYSQSVQTERDSAVQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCVYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRASGAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVEFEDGSQLTVKRADIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDGVKAAKRPRVATVLATTTEDTGRSPEYLAFMESLLQAQGQPGAPF",
                "length": 1021,
                "header": "tr|A0A8I6GK41-1|A0A8I6GK41_RAT Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(9) demethylase  OS=Rattus norvegicus OX=10116 GN=Kdm4b PE=3 SV=1 CANONICAL=A0A0G2JXG2-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 1235392,
                "end_pos": 1181954,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000095576.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000095576.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000093085.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000093085.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "M0RB75-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0G2JXG2/entry#M0RB75-1",
            "sequence": {
                "sequence": "MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRSILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSLKAKLLRRQISVKESRPWRKAEEERRPSLERRREPTRRPGPASHRRRSQPKKSKPEDSRSPGEATAGVAGLDEARGCSRRETMPEEEEEEELSPSQGHEAEGVEEDGRGKPRPTKARSKKKTPSLLSPPLLSAPPALFPAEEVLRLPPQPKSPGPAMGPMAAEGGPPPTALNVVPPGVPGEETEVRPRPIIPMLYVLPRANSSDGDREHAAHPQLAPMELGPEEEDQAQAGDSQGTTSFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEAFPFSGEDDGSDPEALRSLLSLQWKSKAASFQAERKLNAAAALSEPYCAVCTLFYPYSQSVQTEREVLATPGDSAVQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCVYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRASGAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRADIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDGVKAAKRPRVATVLATTTEDTGRSPEYLAFMESLLQAQGQPGAPF",
                "length": 1099,
                "header": "tr|M0RB75-1|A0A0G2JXG2_RAT Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(9) demethylase  OS=Rattus norvegicus OX=10116 GN=Kdm4b PE=3 SV=1 CANONICAL=A0A0G2JXG2-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 1235392,
                "end_pos": 1181954,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000071199.3",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000071199.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000066803.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000066803.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [],
    "pathway": [
        {
            "id": "rno:301128",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:301128",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-3214842",
            "name": "HDMs demethylate histones",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3214842",
            "resource": "Reactome",
            "description": "HDMs demethylate histones"
        },
        {
            "id": "R-RNO-5693565",
            "name": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5693565",
            "resource": "Reactome",
            "description": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
        },
        {
            "id": "R-RNO-9018519",
            "name": "Estrogen-dependent gene expression",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9018519",
            "resource": "Reactome",
            "description": "Estrogen-dependent gene expression"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "E1BA41-1",
            "protein_name": "[histone H3]-trimethyl-L-lysine(9) demethylase",
            "gene_name": "KDM4B",
            "tax_id": 9913,
            "organism": "Bos taurus",
            "sequence": {
                "sequence": "MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALSSPELSTWSASRASLKAKLLRRQISLKENRHWKKTEEERKPSLERKKEQTRRPGLSSHRKRSQPKKPKPDDPRSPGEGAAGVALLEEAGGSTKEEAAPEADPEEEEEEAQLLPQGREAEGSEEDGRGKLRLAKAKSDRKKKSYGSLHPHHPLLPPPPSSQFTEEAPLLDIPGPAPGLEAAEESPLPPPLNVVPPKAPGEEPEAKPRPVIPMLYVVPRPGPTGNKGRVSCQQASEHFAQKGPTWKEQATPMELTGPEEESGASEGQNPSTFSKLKMEIKKSRRHPLGRPPTRSPLSVVKQEASSDEESFPFSGDEDVGDPEALRSLMSLQWKNKASNFQAERKFNVAAALTEPYCAICTLFYPYSQSLQTEKEAPQAALGEGSSAIPPSRSGQKTRPLIPEMCFTASGENTEPLPANSYIGDDGTSPLIACAKCCLQVHASCYGIRPELVNEGWTCSRCTAHAWTAECCLCNLRGGALQMTTDRRWVHVICAIAVPEVRFLNVMERHPVDISGIPEQRWKLKCVYCRKRMKKVSGACIQCSCEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCFKHKSGGHSVQVMRAVSLGQVVITKNRNGLYYRCRVIGTTTQTFYEVNFDDGSYSDNLYPESITSRDCARLGPPPEGEFVELRWTDGNLYRAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLDEELPKRVRSRLSVSTGAPQESVFSGEEVKAAKRPRVGTPRAAEDSGRNPDYPAFMESLLQAQCWPGAPY",
                "length": 1116
            },
            "evidence": [
                {
                    "id": "A0A0G2JXG2",
                    "url": "https://omabrowser.org/oma/group/A0A0G2JXG2/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Bovine",
            "common_name": "Bovine"
        },
        {
            "uniprot_canonical_ac": "I3LBN0-1",
            "protein_name": "[histone H3]-trimethyl-L-lysine(9) demethylase",
            "gene_name": "KDM4B",
            "tax_id": 9823,
            "organism": "Sus scrofa",
            "sequence": {
                "sequence": "MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALSSPELSTWSASRASLKAKLLRRQISLKENRHWKKTEEERKPNLERKKEQTRKPGLSSHRKRSQPKKPKPDDPKSPGEGAAGAAILEEAGGGVKEEAALEADPEEEEEEPQSLPQGRDAEGAEEDGRGKLRPAKSKSERKKKSCGPLHPHQLPPPLPPQFPMEEAPLLESPAPAPGPEATEESPPPPPLNVVPPEAPGEEPEAKPRPIIPMLYVVPRPGPTTGDKGRVSCQQASEHFAQKGPTWKEQVAPMELTGPEEESGAGEVQAPATFSKLKMEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEAFPFSGDEDVGDPEALRSLLSLQWKNKAANFQAERKFNAAAALTEPYCAICTLFYPYSQSLQTEKETPQASLGEGPSATPPSKSGQKTRPLIPEMCFISSGENTEPLPANSYIGDDGTSLLIACAKCCLQVHASCYGIRPELVNEGWTCSRCAAHAWTAECCLCNLRGGALQMTTDRRWIHVICAIAVPEVRFLNVMERHPVDISAIPEQRWKLKCVYCRKRMKKVSGACIQCSCEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCFKHKSGSHNVQVLRAVSLGQVVITKNRNGLYYRCRVIGTTTQTFYEVNFDDGSYSDNLYPESITSRDCVRLGPPPEGEFVELRWTDGNIYRAKFISSVTSHIYQVEFEDGSQLTVKRGDLFTLDEELPKRVRSRLSVSTGAPQENVFSGEEVKAAKRPRVGTPRAAEDSGRNPDYLAFMESLLQAQCRPGASF",
                "length": 1116
            },
            "evidence": [
                {
                    "id": "A0A0G2JXG2",
                    "url": "https://omabrowser.org/oma/group/A0A0G2JXG2/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Pig",
            "common_name": "Pig"
        },
        {
            "uniprot_canonical_ac": "O94953-1",
            "protein_name": "Lysine-specific demethylase 4B",
            "gene_name": "KDM4B",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MGSEDHGAQNPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPTALTSPELSSWSASRASLKAKLLRRSHRKRSQPKKPKPEDPKFPGEGTAGAALLEEAGGSVKEEAGPEVDPEEEEEEPQPLPHGREAEGAEEDGRGKLRPTKAKSERKKKSFGLLPPQLPPPPAHFPSEEALWLPSPLEPPVLGPGPAAMEESPLPAPLNVVPPEVPSEELEAKPRPIIPMLYVVPRPGKAAFNQEHVSCQQAFEHFAQKGPTWKEPVSPMELTGPEDGAASSGAGRMETKARAGEGQAPSTFSKLKMEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEASPFSGEEDVSDPDALRPLLSLQWKNRAASFQAERKFNAAAARTEPYCAICTLFYPYCQALQTEKEAPIASLGKGCPATLPSKSRQKTRPLIPEMCFTSGGENTEPLPANSYIGDDGTSPLIACGKCCLQVHASCYGIRPELVNEGWTCSRCAAHAWTAECCLCNLRGGALQMTTDRRWIHVICAIAVPEARFLNVIERHPVDISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHKSGGHAVQLLRAVSLGQVVITKNRNGLYYRCRVIGAASQTCYEVNFDDGSYSDNLYPESITSRDCVQLGPPSEGELVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGAPQEPAFSGEEAKAAKRPRVGTPLATEDSGRSQDYVAFVESLLQVQGRPGAPF",
                "length": 1096
            },
            "evidence": [
                {
                    "id": "47565949",
                    "url": "http://www.informatics.jax.org/homology/47565949",
                    "database": "MGI"
                },
                {
                    "id": "A0A0G2JXG2",
                    "url": "https://omabrowser.org/oma/group/A0A0G2JXG2/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q91VY5-1",
            "protein_name": "Lysine-specific demethylase 4B",
            "gene_name": "Kdm4b",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSIKAKLLRRQISVKESRPWRKAEEERRREPTRRPGPASHRRRSQPKKSKPEESRSPGEATAGVSTLDEARGCSRGEAMPEDEEEEELLPSQGHEAEGVEEDGRGKPRPTKARNKKKTPSPSSPPLLSAPPALFPTEEVLRPPPQPKSPGPAMGPMAAEGGPPPTPLNVVPPGAPVEEAEVRPRPIIPMLYVLPRTSSTDGDREHSAHAQLAPMELGPEEENQAQAGDSQGTTPFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEAFLFSGEDDVTDPEALRSLLSLQWKNKAASFQAERKFNAAAALSEPYCAICTLFYPYSQSVQTERDSAVQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCIYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRASGAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDDVKAAKRPRVASVLATTTEDTGRSPEYLSFMESLLQAQGRPGAPF",
                "length": 1086
            },
            "evidence": [
                {
                    "id": "47565949",
                    "url": "http://www.informatics.jax.org/homology/47565949",
                    "database": "MGI"
                },
                {
                    "id": "A0A0G2JXG2",
                    "url": "https://omabrowser.org/oma/group/A0A0G2JXG2/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 5,
                "go_terms": [
                    {
                        "name": "histone H3K36 demethylase activity",
                        "id": "GO:0051864",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051864",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "metal ion binding",
                        "id": "GO:0046872",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone demethylase activity",
                        "id": "GO:0032452",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032452",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone H3K9 demethylase activity",
                        "id": "GO:0032454",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032454",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone H3K9me2/H3K9me3 demethylase activity",
                        "id": "GO:0140684",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140684",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleoplasm",
                        "id": "GO:0005654",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chromatin",
                        "id": "GO:0000785",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "pericentric heterochromatin",
                        "id": "GO:0005721",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "chromatin remodeling",
                        "id": "GO:0006338",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "brain development",
                        "id": "GO:0007420",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of gene expression",
                        "id": "GO:0010468",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JXG2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 125,
            "end_pos": 127,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 559,
            "end_pos": 561,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [
        {
            "id": "60200",
            "name": "",
            "equation": "2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "A1A5Q5-1",
                "A0A0G2JXG2-1",
                "A0A0G2K5I7-1",
                "F1LS62-1"
            ],
            "evidence": [
                {
                    "id": "60200",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/60200"
                }
            ]
        },
        {
            "id": "R-RNO-4724279",
            "name": "KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "A0A0G2JXG2-1",
                "F1LS62-1",
                "A1A5Q5-1",
                "Q8CFC1-1",
                "A0A0G2K5I7-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-4724279",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-4724279"
                }
            ]
        },
        {
            "id": "R-RNO-5661120",
            "name": "KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "A0A0G2JXG2-1",
                "F1LS62-1",
                "A1A5Q5-1",
                "Q8CFC1-1",
                "A0A0G2K5I7-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5661120",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5661120"
                }
            ]
        },
        {
            "id": "R-RNO-5682586",
            "name": "HERC2 and PIAS4 are recruited to DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q99MK2-1",
                "A0A0G2JXG2-1",
                "Q9JIM0-1",
                "A0A0G2JUC9-1",
                "Q4KLN8-1",
                "Q9JIL8-1",
                "A0A0G2K5I7-1",
                "D4ACL8-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5682586",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5682586"
                }
            ]
        },
        {
            "id": "R-RNO-5682588",
            "name": "RNF8 binds phosphorylated MDC1 at DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q99MK2-1",
                "A0A0G2JXG2-1",
                "Q9JIM0-1",
                "Q4KLN8-1",
                "Q9JIL8-1",
                "A0A0G2K5I7-1",
                "D4ACL8-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5682588",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5682588"
                }
            ]
        },
        {
            "id": "R-RNO-5682598",
            "name": "ATM phosphorylates HERC2",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q99MK2-1",
                "A0A0G2JXG2-1",
                "Q9JIM0-1",
                "A0A0G2JUC9-1",
                "Q4KLN8-1",
                "Q9JIL8-1",
                "A0A0G2K5I7-1",
                "D4ACL8-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5682598",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5682598"
                }
            ]
        },
        {
            "id": "R-RNO-5682607",
            "name": "PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q99MK2-1",
                "A0A0G2JXG2-1",
                "Q9JIM0-1",
                "A0A0G2JUC9-1",
                "P63281-1",
                "Q4KLN8-1",
                "Q9JIL8-1",
                "A0A0G2K5I7-1",
                "D4ACL8-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5682607",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5682607"
                }
            ]
        },
        {
            "id": "R-RNO-5682858",
            "name": "RNF8 and RNF168 ubiquitinate H2AFX",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q99MK2-1",
                "B2RYR0-1",
                "A0A0G2JXG2-1",
                "Q9JIM0-1",
                "A0A0G2JUC9-1",
                "Q4KLN8-1",
                "Q9JIL8-1",
                "A0A0G2K5I7-1",
                "D4ACL8-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5682858",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5682858"
                }
            ]
        },
        {
            "id": "R-RNO-5682863",
            "name": "RNF168 binds DNA DSBs",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q99MK2-1",
                "B2RYR0-1",
                "A0A0G2JXG2-1",
                "Q9JIM0-1",
                "A0A0G2JUC9-1",
                "Q4KLN8-1",
                "Q9JIL8-1",
                "A0A0G2K5I7-1",
                "D4ACL8-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5682863",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5682863"
                }
            ]
        },
        {
            "id": "R-RNO-5682992",
            "name": "KDM4A,B bind H4K20Me2",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q99MK2-1",
                "A0A0G2JXG2-1",
                "Q9JIM0-1",
                "Q9JIL8-1",
                "A0A0G2K5I7-1",
                "D4ACL8-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5682992",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5682992"
                }
            ]
        },
        {
            "id": "R-RNO-5683077",
            "name": "RNF8 and RNF168 ubiquitinate KDM4A,B",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q99MK2-1",
                "B2RYR0-1",
                "A0A0G2JXG2-1",
                "Q9JIM0-1",
                "A0A0G2JUC9-1",
                "Q4KLN8-1",
                "Q9JIL8-1",
                "A0A0G2K5I7-1",
                "D4ACL8-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5683077",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5683077"
                }
            ]
        },
        {
            "id": "R-RNO-9011949",
            "name": "KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "A0A0G2JXG2-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-9011949",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9011949"
                }
            ]
        },
        {
            "id": "R-RNO-9011952",
            "name": "ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "nucleoplasm",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "A0A0G2JXG2-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-9011952",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9011952"
                }
            ]
        }
    ],
    "reaction_participants": [],
    "reaction_enzymes": [
        {
            "uniprot_ac": "A0A0G2JUC9",
            "gene_name": "Herc2",
            "activity": [
                {
                    "ec_number": "2.3.2.26",
                    "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.",
                    "evidence": [
                        {
                            "id": "A0A0G2JUC9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JUC9"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.2.26",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2JUC9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JUC9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A0G2JXG2",
            "gene_name": "Kdm4b",
            "activity": [
                {
                    "ec_number": "1.14.11.66",
                    "activity": "2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate.",
                    "evidence": [
                        {
                            "id": "A0A0G2JXG2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                        }
                    ]
                },
                {
                    "ec_number": "1.14.11.66",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2JXG2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JXG2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A0G2K5I7",
            "gene_name": "Kdm4a",
            "activity": [
                {
                    "ec_number": "1.14.11.66",
                    "activity": "2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate.",
                    "evidence": [
                        {
                            "id": "A0A0G2K5I7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K5I7"
                        }
                    ]
                },
                {
                    "ec_number": "1.14.11.66",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2K5I7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K5I7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A1A5Q5",
            "gene_name": "Kdm4d",
            "activity": [
                {
                    "ec_number": "1.14.11.66",
                    "activity": "2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate.",
                    "evidence": [
                        {
                            "id": "A1A5Q5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A1A5Q5"
                        }
                    ]
                },
                {
                    "ec_number": "1.14.11.66",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A1A5Q5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A1A5Q5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B2RYR0",
            "gene_name": "Rnf168",
            "activity": [
                {
                    "ec_number": "2.3.2.27",
                    "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.",
                    "evidence": [
                        {
                            "id": "B2RYR0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RYR0"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.2.27",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B2RYR0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RYR0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4ACL8",
            "gene_name": "Atm",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "D4ACL8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ACL8"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D4ACL8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ACL8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LS62",
            "gene_name": "Kdm4c",
            "activity": [
                {
                    "ec_number": "1.14.11.66",
                    "activity": "2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate.",
                    "evidence": [
                        {
                            "id": "F1LS62",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LS62"
                        }
                    ]
                },
                {
                    "ec_number": "1.14.11.66",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LS62",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LS62"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P63281",
            "gene_name": "Ube2i",
            "activity": [
                {
                    "ec_number": "2.3.2.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P63281",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P63281"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q4KLN8",
            "gene_name": "Rnf8",
            "activity": [
                {
                    "ec_number": "2.3.2.27",
                    "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.",
                    "evidence": [
                        {
                            "id": "Q4KLN8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4KLN8"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.2.27",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q4KLN8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q4KLN8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q8CFC1",
            "gene_name": "Riox2",
            "activity": [
                {
                    "ec_number": "1.14.11.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q8CFC1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CFC1"
                        }
                    ]
                },
                {
                    "ec_number": "1.14.11.79",
                    "activity": "2-oxoglutarate + L-histidyl-[protein] + O2 = (3S)-3-hydroxy-L-histidyl-[protein] + CO2 + succinate.",
                    "evidence": [
                        {
                            "id": "Q8CFC1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8CFC1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q99MK2",
            "gene_name": "Kat5",
            "activity": [
                {
                    "ec_number": "2.3.1.48",
                    "activity": "acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone].",
                    "evidence": [
                        {
                            "id": "Q99MK2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q99MK2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q99MK2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q99MK2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q99MK2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q99MK2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9JIL8",
            "gene_name": "Rad50",
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                {
                    "ec_number": "3.6.-.-",
                    "activity": "",
                    "evidence": [
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                            "id": "Q9JIL8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JIL8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q9JIM0",
            "gene_name": "Mre11",
            "activity": [
                {
                    "ec_number": "3.1.-.-",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q9JIM0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9JIM0"
                        }
                    ]
                }
            ]
        }
    ],
    "biomarkers": [],
    "structures": [
        {
            "pdb_id": "AF-A0A0G2JXG2-F1",
            "pdb_chain": "global",
            "start_pos": 1,
            "end_pos": 1086,
            "overlap": "1.0",
            "method": "AlphaFold",
            "type": "alphafold",
            "resolution": -1.0,
            "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A0G2JXG2-F1.pdb"
        }
    ],
    "synthesized_glycans": [],
    "enzyme_annotation": [
        {
            "ec_number": "1.14.11.66",
            "ec_name": "2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate.",
            "evidence": [
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                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.66"
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                    "id": "1.14.11.66",
                    "database": "BRENDA Enzymes",
                    "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.66"
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    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 125,
                "end_pos": 127
            },
            {
                "start_pos": 559,
                "end_pos": 561
            }
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}
