{ "uniprot_canonical_ac": "P12104-1", "uniprot_ac": "P12104", "uniprot_id": "FABPI_HUMAN", "mass": { "chemical_mass": 15237.0, "monoisotopic_mass": 15237.0 }, "refseq": { "ac": "NP_000125", "name": "fatty acid-binding protein, intestinal", "summary": "The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis. [provided by RefSeq, Aug 2017].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" }, "gene_names": [ { "name": "FABP2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P12104", "id": "P12104" }, { "name": "FABP2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125", "id": "NP_000125" }, { "name": "FABPI; I-FABP", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125", "id": "NP_000125" }, { "name": "FABPI", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/P12104", "id": "P12104" } ], "protein_names": [ { "name": "Fatty acid-binding protein, intestinal", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P12104" }, { "name": "Fatty acid-binding protein 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P12104" }, { "name": "I-FABP", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P12104" }, { "name": "Intestinal-type fatty acid-binding protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P12104" }, { "name": "fatty acid-binding protein, intestinal", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125", "id": "NP_000125" }, { "name": "intestinal-type fatty acid-binding protein; fatty acid binding protein 2, intestinal", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125", "id": "NP_000125" } ], "function": [ { "annotation": "FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104#function" } ] }, { "annotation": "Fatty acid binding protein 1 (FABP1) and fatty acid binding protein 2 (FABP2) as a link between diabetic nephropathy and subclinical atherosclerosis in children and adolescents with type 1 diabetes.", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" }, { "database": "PubMed", "id": "36758511", "url": "https://glygen.org/publication/PubMed/36758511" } ] }, { "annotation": "Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" }, { "database": "PubMed", "id": "37076872", "url": "https://glygen.org/publication/PubMed/37076872" } ] }, { "annotation": "Increased intestinal-fatty acid binding protein in obesity-associated type 2 diabetes mellitus. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" }, { "database": "PubMed", "id": "36701395", "url": "https://glygen.org/publication/PubMed/36701395" } ] }, { "annotation": "Serum Levels of IFABP2 and Differences in Lactobacillus and Porphyromonas gingivalis Abundance on Gut Microbiota Are Associated with Poor Therapeutic Response in Rheumatoid Arthritis: A Pilot Study. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" }, { "database": "PubMed", "id": "36768285", "url": "https://glygen.org/publication/PubMed/36768285" } ] }, { "annotation": "The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis. [provided by RefSeq, Aug 2017].", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" } ] }, { "annotation": "[Ala54Thr polymorphism of the fatty acid transporter gene (FABP2) in patients with type 2 diabetes mellitus in Yakutia]. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" }, { "database": "PubMed", "id": "38159016", "url": "https://glygen.org/publication/PubMed/38159016" } ] } ], "disease": [], "snv": [], "mutagenesis": [ { "start_pos": 123, "end_pos": 123, "sequence_org": "V", "sequence_mut": "G", "comment": "Reduced stability.", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" }, { "database": "PubMed", "id": "14567680", "url": "https://glygen.org/publication/PubMed/14567680" } ] }, { "start_pos": 39, "end_pos": 39, "sequence_org": "L", "sequence_mut": "G", "comment": "Reduced stability.", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" }, { "database": "PubMed", "id": "14567680", "url": "https://glygen.org/publication/PubMed/14567680" } ] }, { "start_pos": 64, "end_pos": 64, "sequence_org": "E", "sequence_mut": "G", "comment": "Localized reduction in stability.", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" }, { "database": "PubMed", "id": "14567680", "url": "https://glygen.org/publication/PubMed/14567680" } ] }, { "start_pos": 65, "end_pos": 65, "sequence_org": "L", "sequence_mut": "A", "comment": "Reduced stability.", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" }, { "database": "PubMed", "id": "14567680", "url": "https://glygen.org/publication/PubMed/14567680" } ] }, { "start_pos": 65, "end_pos": 65, "sequence_org": "L", "sequence_mut": "G", "comment": "Reduced stability.", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" }, { "database": "PubMed", "id": "14567680", "url": "https://glygen.org/publication/PubMed/14567680" } ] }, { "start_pos": 67, "end_pos": 67, "sequence_org": "V", "sequence_mut": "G", "comment": "Localized reduction in stability.", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" }, { "database": "PubMed", "id": "14567680", "url": "https://glygen.org/publication/PubMed/14567680" } ] }, { "start_pos": 90, "end_pos": 90, "sequence_org": "L", "sequence_mut": "G", "comment": "Reduced stability.", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" }, { "database": "PubMed", "id": "14567680", "url": "https://glygen.org/publication/PubMed/14567680" } ] } ], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "52.56", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "59.92", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "46.4", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Uterus", "namespace": "UBERON", "id": "0000995", "url": "http://purl.obolibrary.org/obo/UBERON_0000995" }, "score": "49.96", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "17.43", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "92.2", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Colon", "namespace": "UBERON", "id": "0001155", "url": "http://purl.obolibrary.org/obo/UBERON_0001155" }, "score": "58.68", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "43.25", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "36.71", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Lung", "namespace": "UBERON", "id": "0002048", "url": "http://purl.obolibrary.org/obo/UBERON_0002048" }, "score": "47.6", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "48.65", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "34.98", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "34.27", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000145384", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000145384" } ] } ], "expression_disease": [ { "significant": "Yes", "trend": "up", "name": "Prostate cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "P12104", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P12104" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": 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"" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": 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"MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate carcinoma", "description": "Prostate carcinoma that has developed in relatives of patients with a history of prostate carcinoma." }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "familial prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate cancer", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "hereditary prostate carcinoma", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, familial, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, somatic", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0023122", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0023122", "name": "prostate cancer, 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}, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer susceptibility, X-linked", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Stomach cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "P12104", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P12104" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", 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"https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", 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"description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, intestinal", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ] } ] }, { "significant": "No", "trend": "up", "name": "Urinary bladder cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "P12104", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P12104" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary 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"https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ] } ] }, { "significant": "No", "trend": "down", "name": "Head and neck cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:11934", "evidence": [ { "database": "BioXpress", "id": "P12104", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P12104" } ], "disease": [ { "disease_id": "DOID:11934", "recommended_name": { "id": "DOID:11934", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:11934", "name": "head and neck cancer", "description": "An organ system cancer that arises in the head or neck region. 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"https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P12104" } ], "disease": [ { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": 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Physiol.", "date": "1999", "authors": "Darimont C, Gradoux N, de Pover A", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" } ], "reference": [ { "type": "PubMed", "id": "10070036", "url": "https://glygen.org/publication/PubMed/10070036" } ] }, { "title": "Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism.", "journal": "Biochemistry", "date": "2003", "authors": "Zhang F, Lucke C, Baier LJ, Sacchettini JC, Hamilton JA", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" } ], "reference": [ { "type": "PubMed", "id": "12809489", "url": "https://glygen.org/publication/PubMed/12809489" } ] }, { "title": "The association of Ala54Thr variant of intestinal fatty acid binding protein gene with general and regional adipose tissue depots.", "journal": "Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih", "date": "1999", "authors": "Kunsan X, Taisan Z, Weiping J, Duoqi S, Wei D, Jie L, Junxi L, Rong Z", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" } ], "reference": [ { "type": "PubMed", "id": "12899384", "url": "https://glygen.org/publication/PubMed/12899384" } ] }, { "title": "Intestinal-type and liver-type fatty acid-binding protein in the intestine. Tissue distribution and clinical utility.", "journal": "Clin. Biochem.", "date": "2003", "authors": "Pelsers Maurice M A L, Namiot Zbigniew, Kisielewski Wojciech, Namiot Andrzej, Januszkiewicz Marcin, Hermens Wim T, Glatz Jan F C", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" } ], "reference": [ { "type": "PubMed", "id": "14563446", "url": "https://glygen.org/publication/PubMed/14563446" } ] }, { "title": "Consequences of single-site mutations in the intestinal fatty acid binding protein.", "journal": "Biochemistry", "date": "2003", "authors": "Rajabzadeh M, Kao J, Frieden C", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" } ], "reference": [ { "type": "PubMed", "id": "14567680", "url": "https://glygen.org/publication/PubMed/14567680" } ] }, { "title": "Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Jenkins CM, Mancuso DJ, Yan W, Sims HF, Gibson B, Gross RW", "evidence": [ { "database": "Reactome", "id": "R-HSA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-163560" } ], "reference": [ { "type": "PubMed", "id": "15364929", "url": "https://glygen.org/publication/PubMed/15364929" } ] }, { "title": "Physical association between the adipocyte fatty acid-binding protein and hormone-sensitive lipase: a fluorescence resonance energy transfer analysis.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Smith AJ, Sanders MA, Thompson BR, Londos C, Kraemer FB, Bernlohr DA", "evidence": [ { "database": "Reactome", "id": "R-HSA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-163560" } ], "reference": [ { "type": "PubMed", "id": "15456755", "url": "https://glygen.org/publication/PubMed/15456755" } ] }, { "title": "Molecular screening for GS2 lipase regulators: inhibition of keratinocyte retinylester hydrolysis by TIP47.", "journal": "The Journal of investigative dermatology", "date": "2006", "authors": "Gao JG, Simon M", "evidence": [ { "database": "Reactome", "id": "R-HSA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-163560" } ], "reference": [ { "type": "PubMed", "id": "16741517", "url": "https://glygen.org/publication/PubMed/16741517" } ] }, { "title": "A comparative study of human GS2, its paralogues, and its rat orthologue.", "journal": "Biochemical and biophysical research communications", "date": "2007", "authors": "Gao JG, Simon M", "evidence": [ { "database": "Reactome", "id": "R-HSA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-163560" } ], "reference": [ { "type": "PubMed", "id": "17603008", "url": "https://glygen.org/publication/PubMed/17603008" } ] }, { "title": "GS2 as a retinol transacylase and as a catalytic dyad independent regulator of retinylester accretion.", "journal": "Molecular genetics and metabolism", "date": "2009", "authors": "Gao JG, Shih A, Gruber R, Schmuth M, Simon M", "evidence": [ { "database": "Reactome", "id": "R-HSA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-163560" } ], "reference": [ { "type": "PubMed", "id": "19181555", "url": "https://glygen.org/publication/PubMed/19181555" } ] }, { "title": "The human fatty acid-binding protein family: evolutionary divergences and functions.", "journal": "Human genomics", "date": "2011", "authors": "Smathers RL, Petersen DR", "evidence": [ { "database": "Reactome", "id": "R-HSA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-163560" } ], "reference": [ { "type": "PubMed", "id": "21504868", "url": "https://glygen.org/publication/PubMed/21504868" } ] }, { "title": "The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships.", "journal": "J. Biol. Chem.", "date": "1987", "authors": "Sweetser DA, Birkenmeier EH, Klisak IJ, Zollman S, Sparkes RS, Mohandas T, Lusis AJ, Gordon JI", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" } ], "reference": [ { "type": "PubMed", "id": "2824476", "url": "https://glygen.org/publication/PubMed/2824476" } ] }, { "title": "Increased intestinal-fatty acid binding protein in obesity-associated type 2 diabetes mellitus.", "journal": "PloS one", "date": "2023", "authors": "Tahapary Dicky L, Fatya Atikah I, Kurniawan Farid, Marcella Cicilia, Rinaldi Ikhwan, Tarigan Tri J E, Harbuwono Dante S, Yunir Em, Soewondo Pradana, Purnamasari Dyah", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" } ], "reference": [ { "type": "PubMed", "id": "36701395", "url": "https://glygen.org/publication/PubMed/36701395" } ] }, { "title": "Fatty acid binding protein 1 (FABP1) and fatty acid binding protein 2 (FABP2) as a link between diabetic nephropathy and subclinical atherosclerosis in children and adolescents with type 1 diabetes.", "journal": "Journal of diabetes and its complications", "date": "2023-03", "authors": "Abo El-Asrar Mohamed, Ismail Eman Abdel Rahman, Elnhrawy Alaa Mohamed, Thabet Rasha Adel", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" } ], "reference": [ { "type": "PubMed", "id": "36758511", "url": "https://glygen.org/publication/PubMed/36758511" } ] }, { "title": "Serum Levels of IFABP2 and Differences in Lactobacillus and Porphyromonas gingivalis Abundance on Gut Microbiota Are Associated with Poor Therapeutic Response in Rheumatoid Arthritis: A Pilot Study.", "journal": "International journal of molecular sciences", "date": "2023-01-19", "authors": "Zaragoza-Garc\u00eda Oscar, Castro-Alarc\u00f3n Natividad, P\u00e9rez-Rubio Gloria, Falf\u00e1n-Valencia Ramc\u00e9s, Brice\u00f1o Olivia, Navarro-Zarza Jos\u00e9 Eduardo, Parra-Rojas Isela, Tello Mario, Guzm\u00e1n-Guzm\u00e1n Iris Paola", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" } ], "reference": [ { "type": "PubMed", "id": "36768285", "url": "https://glygen.org/publication/PubMed/36768285" } ] }, { "title": "Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population.", "journal": "BMC medicine", "date": "2023-04-19", "authors": "Zhang Zhu, Li Haobo, Weng Haoyi, Zhou Geyu, Chen Hong, Yang Guoru, Zhang Ping, Zhang Xiangyan, Ji Yingqun, Ying Kejing, Liu Bo, Xu Qixia, Tang Yongjun, Zhu Guangfa, Liu Zhihong, Xia Shuyue, Yang Xiaohong, Dong Lixia, Zhu Ling, Zeng Mian, Yuan Yadong, Yang Yuanhua, Zhang Nuofu, Xu Xiaomao, Pang Wenyi, Zhang Meng, Zhang Yu, Zhen Kaiyuan, Wang Dingyi, Lei Jieping, Wu Sinan, Shu Shi, Zhang Yunxia, Zhang Shuai, Gao Qian, Huang Qiang, Deng Chao, Fu Xi, Chen Gang, Duan Wenxin, Wan Jun, Xie Wanmu, Zhang Peng, Wang Shengfeng, Yang Peiran, Zuo Xianbo, Zhai Zhenguo, Wang Chen,", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" } ], "reference": [ { "type": "PubMed", "id": "37076872", "url": "https://glygen.org/publication/PubMed/37076872" } ] }, { "title": "[Ala54Thr polymorphism of the fatty acid transporter gene (FABP2) in patients with type 2 diabetes mellitus in Yakutia].", "journal": "Terapevticheskii arkhiv", "date": "2023-11-23", "authors": "Sydykova L A, Pavlova N I, Bochurov A A, Alekseev V A, Krylov A V, Kurtanov K A, Shestakova M V", "evidence": [ { "database": "RefSeq", "id": "NP_000125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_000125" } ], "reference": [ { "type": "PubMed", "id": "38159016", "url": "https://glygen.org/publication/PubMed/38159016" } ] }, { "title": "An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance.", "journal": "The Journal of clinical investigation", "date": "1995", "authors": "Baier LJ, Sacchettini JC, Knowler WC, Eads J, Paolisso G, Tataranni PA, Mochizuki H, Bennett PH, Bogardus C, Prochazka M", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" } ], "reference": [ { "type": "PubMed", "id": "7883976", "url": "https://glygen.org/publication/PubMed/7883976" } ] }, { "title": "Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit.", "journal": "J. Biomol. NMR", "date": "1997", "authors": "Zhang F, L\u00fccke C, Baier L J, Sacchettini J C, Hamilton J A", "evidence": [ { "database": "UniProtKB", "id": "P12104", "url": "https://www.uniprot.org/uniprot/P12104" } ], "reference": [ { "type": "PubMed", "id": "9204553", "url": "https://glygen.org/publication/PubMed/9204553" } ] } ], "pathway": [ { "id": "hsa:2169", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:2169", "resource": "KEGG Pathway" }, { "id": "R-HSA-163560", "name": "Triglyceride catabolism", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-163560", "resource": "Reactome", "description": "Triglyceride catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "P02693-1", "protein_name": "Fatty acid-binding protein, intestinal", "gene_name": "Fabp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFDGTWKVDRNENYEKFMEKMGINVVKRKLGAHDNLKLTITQEGNKFTVKESSNFRNIDVVFELGVDFAYSLADGTELTGTWTMEGNKLVGKFKRVDNGKELIAVREISGNELIQTYTYEGVEAKRIFKKE", "length": 132 }, "evidence": [ { "id": "45916733", "url": "http://www.informatics.jax.org/homology/45916733", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "P55050-1", "protein_name": "Fatty acid-binding protein, intestinal", "gene_name": "Fabp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFDGTWKVDRNENYEKFMEKMGINVMKRKLGAHDNLKLTITQDGNKFTVKESSNFRNIDVVFELGVNFPYSLADGTELTGAWTIEGNKLIGKFTRVDNGKELIAVREVSGNELIQTYTYEGVEAKRFFKKE", "length": 132 }, "evidence": [ { "id": "45916733", "url": "http://www.informatics.jax.org/homology/45916733", "database": "MGI" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "long-chain fatty acid binding", "id": "GO:0036041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036041", 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