{ "uniprot_canonical_ac": "P0DP72-1", "uniprot_ac": "P0DP72", "uniprot_id": "VSXL2_HUMAN", "mass": { "chemical_mass": 81629.0, "monoisotopic_mass": 81629.0 }, "refseq": {}, "gene_names": [ { "name": "VSIG10L2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P0DP72", "id": "P0DP72" } ], "protein_names": [ { "name": "V-set and immunoglobulin domain-containing protein 10-like 2", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P0DP72" } ], "function": [], "disease": [], "snv": [ { "evidence": [ { "id": "rs941514159", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs941514159" }, { "id": "rs941514159", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs941514159#frequency_tab" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 265, "end_pos": 265, "sequence_org": "T", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (TLS->NLS).", "chr_id": "11", "chr_pos": "125950098", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T265", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1314099404", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1314099404" }, { "id": "rs1314099404", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs1314099404" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 319, "end_pos": 319, "sequence_org": "T", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (TQT->NQT).", "chr_id": "11", "chr_pos": "125950260", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T319", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs747257516", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs747257516" }, { "id": "rs747257516", "database": "ENSEMBL", "url": "https://www.ensembl.org/id/rs747257516" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "start_pos": 376, "end_pos": 376, "sequence_org": "N", "sequence_mut": "Y", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->YVT).", "chr_id": "11", "chr_pos": "125951050", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N376", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1463497521", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1463497521" }, { "id": "rs1463497521", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs1463497521#frequency_tab" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "start_pos": 602, "end_pos": 602, "sequence_org": "N", "sequence_mut": "K", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->KVT).", "chr_id": "11", "chr_pos": "125954106", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N602", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1398689790", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1398689790" }, { "id": "rs1398689790", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs1398689790#frequency_tab" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "start_pos": 604, "end_pos": 604, "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NVT->NVI).", "chr_id": "11", "chr_pos": "125954111", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T604", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs997875083", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs997875083" }, { "id": "rs997875083", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs997875083#frequency_tab" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "start_pos": 630, "end_pos": 630, "sequence_org": "T", "sequence_mut": "M", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NLT->NLM).", "chr_id": "11", "chr_pos": "125954189", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T630", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P0DP72", "url": "https://www.uniprot.org/uniprot/P0DP72" } ], "common_name": "Human" } ], "gene": [ { "name": "VSIG10L2", "url": "https://www.uniprot.org/uniprot/P0DP72", "locus": { "chromosome": "11", "start_pos": 125958647, "end_pos": 125946044, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSG00000283703", "url": "https://www.ensembl.org/id/ENSG00000283703" } ] } } ], "crossref": [ { "id": "ENSG00000283703", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000283703", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "VSIG10L2", "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=VSIG10L2", "database": "GeneCards", "categories": [ "Gene Annotation", "Organism-specific" ] }, { "id": "27879", "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=27879", "database": "HGNC", "categories": [ "Organism-specific" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NX_P0DP72", "url": "https://www.nextprot.org/entry/NX_P0DP72", "database": "neXtProt", "categories": [ "Protein", "Organism-specific" ] }, { "id": "DPVNRTH", "url": "https://omabrowser.org/oma/group/DPVNRTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13927", "url": "http://pfam.xfam.org/family/PF13927", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "P0DP72", "url": "https://pharos.nih.gov/targets/P0DP72", "database": "PHAROS", "categories": [ "Organism-specific" ] }, { "id": "PR_P0DP72", "url": "http://purl.obolibrary.org/obo/PR_P0DP72", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0A1W2PP72", "url": "https://www.uniprot.org/uniprot/A0A1W2PP72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1W2PP72-1", "url": "https://www.uniprot.org/uniprot/A0A1W2PP72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5KPR9", "url": "https://www.uniprot.org/uniprot/A0A8I5KPR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5KPR9-1", "url": "https://www.uniprot.org/uniprot/A0A8I5KPR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0DP72", "url": "https://www.uniprot.org/uniprot/P0DP72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0DP72-1", "url": "https://www.uniprot.org/uniprot/P0DP72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGPAPLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQYAARHPETFPRLETPTTTPGLDPAQETTDSPVNVTITVTATP", "length": 767, "header": "sp|P0DP72-1|VSXL2_HUMAN Isoform 1 of V-set and immunoglobulin domain-containing protein 10-like 2 OS=Homo sapiens OX=9606 GN=VSIG10L2 PE=3 SV=1 CANONICAL=P0DP72-1" }, "isoforms": [ { "isoform_ac": "A0A1W2PP72-1", "url": "", "sequence": { "sequence": "FIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLGYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKGAKAPTEGFQRRC", "length": 124, "header": "tr|A0A1W2PP72-1|A0A1W2PP72_HUMAN Computationally mapped isoform of V-set and immunoglobulin domain containing 10 like 2 OS=Homo sapiens OX=9606 GN=VSIG10L2 PE=4 SV=1 CANONICAL=P0DP72-1" }, "locus": { "chromosome": "11", "start_pos": 125955653, "end_pos": 125951866, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000640497.1", "url": "https://www.ensembl.org/id/ENST00000640497.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000491366.1", "url": "https://www.ensembl.org/id/ENSP00000491366.1" } ] } }, { "isoform_ac": "A0A8I5KPR9-1", "url": "", "sequence": { "sequence": "MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGPAPLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQYAARHPETFPRLGQLLVPTEQRHQQRGSREDAEAPAGLETPTTTPGLDPAQETTDSPVNVTITVTATP", "length": 793, "header": "tr|A0A8I5KPR9-1|A0A8I5KPR9_HUMAN Computationally mapped isoform of V-set and immunoglobulin domain containing 10 like 2 OS=Homo sapiens OX=9606 GN=VSIG10L2 PE=4 SV=1 CANONICAL=P0DP72-1" }, "locus": { "chromosome": "11", "start_pos": 125955911, "end_pos": 125946056, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000686984.1", "url": "https://www.ensembl.org/id/ENST00000686984.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000509422.1", "url": "https://www.ensembl.org/id/ENSP00000509422.1" } ] } }, { "isoform_ac": "P0DP72-1", "url": "", "sequence": { "sequence": "MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGPAPLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQYAARHPETFPRLETPTTTPGLDPAQETTDSPVNVTITVTATP", "length": 767, "header": "sp|P0DP72-1|VSXL2_HUMAN Isoform 1 of V-set and immunoglobulin domain-containing protein 10-like 2 OS=Homo sapiens OX=9606 GN=VSIG10L2 PE=3 SV=1 CANONICAL=P0DP72-1" }, "locus": { "chromosome": "11", "start_pos": 125955911, "end_pos": 125946056, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000638636.2", "url": "https://www.ensembl.org/id/ENST00000638636.2" }, { "database": "Ensembl Peptide", "id": "ENSP00000491467.1", "url": "https://www.ensembl.org/id/ENSP00000491467.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 376, "start_aa": "Asn", "end_pos": 376, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn376", "evidence": [ { "id": "P0DP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0DP72#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 602, "start_aa": "Asn", "end_pos": 602, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn602", "evidence": [ { "id": "P0DP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0DP72#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 628, "start_aa": "Asn", "end_pos": 628, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn628", "evidence": [ { "id": "P0DP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0DP72#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K8R1-1", "protein_name": "V-set and immunoglobulin domain containing 10 like 2", "gene_name": "Vsig10l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVCLSAHHRPSCRLLILFCLLHPGASDQPYPTLNTPGEEASSIQGVRGKSVDLECRTGAAPVAVLWSFAPLGSLVLRPVAVTNGVSSKVESWALALGVVSLRNSTLVIEELRESACGHFLCQTLLMSGGQVHTTYSYLTLTVLVPVSKPRVQLNDLSPVEGVSVVATCAVREGTEPLAFSWHHHTPQGPGEVLVGLSQPRLQLDPVNRTHLGWYMCSVGNAVNELKSDGAFLDVVYGPDKPVITVEPLGLSEDGIWASEKEEVTLSCLAASNPPSHYVWFRDNSQIHTGPTYIIASASRTHTGLYTCLAHNRHLDTHTQTTVQLTIYYPPEGQPSCAVLPTLEGVTLLCAWPGGFPNAQLHWEGPQGIGPSASSNVTWSYTVTGLPNGSVFTCMGQHPTLAIPIFCRVTLWEPSGSPTCWTTATVGDQFIMLSCEWPGGEPPAMLSWLDRQQQSLGDLSPSQAVYLLQAQSELAGREFTCQGSHPLKAPGSHCQLRLEVPQLTVTEPRVSVLEGEEAWLGCALQRGTPPAQLLWLGPQQQQLEGSTFGFTLHPEGTHLRLQVRDADPAHHRGTYQCVARNALGNSSQSVLLEILSKCKGCVCSRGYPAPPNVTISRLTYRRQRREVQLQWAIYGPGNLTGFLVQQRASVPSSEDGAWEVAASDIEPESRDRHLGGLDPAVLYAFRILAMNHHTAGHPSEVKTPVDPAFSAYPAVLGAAGTGAVVALATSLLVFQYAARHPHTFPCTETASITSSPDPIQESIDAPVNVTITVTATP", "length": 776 }, "evidence": [ { "id": "P0DP72", "url": "https://omabrowser.org/oma/group/P0DP72/", "database": "OMA" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A140LHF2-1", "protein_name": "V-set and immunoglobulin domain-containing protein 10-like 2", "gene_name": "Vsig10l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGLSAHHRPLGCRLLILFCLLHPGASGQPYPTSNTAGEEALSVQGVRGSSVELECRTGPAPMAVLWSFTPLGSLVLQPVAVTSGASSKVESGALALGVVSLRNSSLVIEELREGARGHFLCQTLLVSGGQVHTAYLYLMLTVLVPVSKPRVQLNDPSPVEGVSVVATCAVREGTEPLTFSWHHHMPQGPGEVLVGLSEPRLQLDPVNRTHLGWYTCSVSNVVNQLKSDGAFLDVIYGPDKPVITVEPLGFSEDGFWASEREEVTLSCLAASNPPSHYVWFRDDSQIHTGPTYIIASASRTHTGLYTCLAHNRHLDTHTQTTVQLIIYYPPEGQPSCAVLPTLGVVTLLCTWPGGFPNAQLHWEGPQGIGPSASGNVTWSYTTTGLPNGSIFSCTGQHPTLAMPIFCRVTLWEPPGSPTCWTTATVGDQYIMLSCEWPGGEPPAMLSWLDRQQSLGDLGSSQAVHLLQAQSDLAGREFTCQGSHPLTAPGSHCRLRLEVPQLTVAEPRVSVLEGEEAWLGCALQRGTPPAQLLWLGPQQQQLEGSTPGFILHPEGTHLRLQVRDADPAHHRGTYQCVARNALGNSSQSVLLEVLSECKGFVCPCGYPTPPNVTISRLTYRRQRREVQLQWAIYGPGNLTGFLVQQRASVPSSEAGAWEVAASDIEPESRDRRLGGLDPGVLYAFRILAMNHHTAGYPSEVKTPVDPAFSAYPAVLGAAGTGVVVALATSLLVFQYAARHPHTFPCTETASTTSSSDPIQESIDAPVNVTITVTATP", "length": 776 }, "evidence": [ { "id": "P0DP72", "url": "https://omabrowser.org/oma/group/P0DP72/", "database": "OMA" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "P0DP72", "url": "https://www.uniprot.org/uniprot/P0DP72" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P0DP72", "url": "https://www.uniprot.org/uniprot/P0DP72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "P0DP72", "url": "https://www.uniprot.org/uniprot/P0DP72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "P0DP72", "url": "https://www.uniprot.org/uniprot/P0DP72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 376, 602, 628 ], "o_linked_sites": [], "snv_sites": [ 265, 319, 376, 602, 604, 630 ], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 585, "end_pos": 587 }, { "start_pos": 602, "end_pos": 604 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 758, "end_pos": 760 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 3 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 3 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }