{
    "uniprot_canonical_ac": "P0DN82-1",
    "uniprot_ac": "P0DN82",
    "uniprot_id": "O12D1_HUMAN",
    "mass": {
        "chemical_mass": 36420.0,
        "monoisotopic_mass": 36420.0
    },
    "refseq": {
        "ac": "NP_001335137",
        "name": "olfactory receptor 12D1",
        "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017].",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335137"
    },
    "gene_names": [
        {
            "name": "OR12D1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P0DN82",
            "id": "P0DN82"
        },
        {
            "name": "OR12D1P",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P0DN82",
            "id": "P0DN82"
        },
        {
            "name": "OR12D1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335137",
            "id": "NP_001335137"
        },
        {
            "name": "hs6M1-19; OR12D1P",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335137",
            "id": "NP_001335137"
        }
    ],
    "protein_names": [
        {
            "name": "Olfactory receptor 12D1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P0DN82"
        },
        {
            "name": "olfactory receptor 12D1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335137",
            "id": "NP_001335137"
        },
        {
            "name": "olfactory receptor, family 12, subfamily D, member 1 pseudogene; olfactory receptor 12D1 pseudogene",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335137",
            "id": "NP_001335137"
        }
    ],
    "function": [
        {
            "annotation": "Odorant receptor.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P0DN82",
                    "url": "https://www.uniprot.org/uniprot/P0DN82#function"
                }
            ]
        },
        {
            "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017].",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001335137",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335137"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [
        {
            "significant": "No",
            "trend": "up",
            "name": "Lung cancer [DO disease name]",
            "url": "http://disease-ontology.org/term/DOID:1324",
            "evidence": [
                {
                    "database": "BioXpress",
                    "id": "P0DN82",
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P0DN82"
                }
            ],
            "disease": [
                {
                    "disease_id": "DOID:1324",
                    "recommended_name": {
                        "id": "DOID:1324",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1324",
                        "name": "lung cancer",
                        "description": "A respiratory system cancer that is located_in the lung."
                    },
                    "synonyms": [
                        {
                            "id": "MONDO:0012159",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                            "name": "lung cancer susceptibility 1",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012159",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                            "name": "LNCR1",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012159",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                            "name": "lung cancer susceptibility",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012159",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                            "name": "lung cancer susceptibility 1",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012942",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012942",
                            "name": "lung cancer susceptibility 3",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012942",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012942",
                            "name": "LNCR3",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012942",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012942",
                            "name": "lung cancer susceptibility 3",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012942",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012942",
                            "name": "adenocarcinoma of lung, susceptibility to",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012955",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012955",
                            "name": "lung cancer susceptibility 4",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012955",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012955",
                            "name": "LNCR4",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0012955",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0012955",
                            "name": "lung cancer susceptibility 4",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0013631",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                            "name": "lung cancer susceptibility 5",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0013631",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                            "name": "LNCR5",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0013631",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                            "name": "lung cancer susceptibility 5",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "lung cancer",
                            "description": "A malignant neoplasm involving the lung."
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "adenocarcinoma of lung, somatic",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "cancer of lung",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "lung cancer",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "lung cancer, protection against, autosomal dominant, somatic mutation",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "lung cancer, resistance to, autosomal dominant, somatic mutation",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "lung cancer, somatic",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "malignant lung neoplasm",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "malignant lung tumor",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "malignant lung tumour",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "malignant neoplasm of lung",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "malignant neoplasm of the lung",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "malignant tumor of lung",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "malignant tumor of the lung",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "malignant tumour of lung",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "malignant tumour of the lung",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "nonsmall cell lung cancer, somatic",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "Nonsmall cell lung cancer",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "alveolar cell carcinoma",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "lung cancer, protection against",
                            "description": ""
                        },
                        {
                            "id": "MONDO:0008903",
                            "resource": "MONDO",
                            "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                            "name": "lung neoplasm",
                            "description": ""
                        },
                        {
                            "id": "MIM:211980",
                            "resource": "MIM",
                            "url": "https://www.omim.org/entry/211980",
                            "name": "Lung cancer",
                            "description": "Lung cancer"
                        }
                    ]
                }
            ]
        },
        {
            "significant": "Yes",
            "trend": "up",
            "name": "Kidney cancer [DO disease name]",
            "url": "http://disease-ontology.org/term/DOID:263",
            "evidence": [
                {
                    "database": "BioXpress",
                    "id": "P0DN82",
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P0DN82"
                }
            ],
            "disease": [
                {
                    "disease_id": "DOID:263",
                    "recommended_name": {
                        "id": "DOID:263",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:263",
                        "name": "kidney cancer",
                        "description": "A urinary system cancer that is located_in the kidney."
                    },
                    "synonyms": [
                        {
                            "id": "DOID:263",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:263",
                            "name": "malignant neoplasm of kidney except pelvis",
                            "description": ""
                        },
                        {
                            "id": "DOID:263",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:263",
                            "name": "malignant tumour of kidney",
                            "description": ""
                        },
                        {
                            "id": "DOID:263",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:263",
                            "name": "renal cancer",
                            "description": ""
                        }
                    ]
                }
            ]
        },
        {
            "significant": "No",
            "trend": "up",
            "name": "Liver cancer [DO disease name]",
            "url": "http://disease-ontology.org/term/DOID:3571",
            "evidence": [
                {
                    "database": "BioXpress",
                    "id": "P0DN82",
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P0DN82"
                }
            ],
            "disease": [
                {
                    "disease_id": "DOID:3571",
                    "recommended_name": {
                        "id": "DOID:3571",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:3571",
                        "name": "liver cancer",
                        "description": "A hepatobiliary system cancer that is located_in the liver."
                    },
                    "synonyms": [
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "Ca liver - primary",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "Resectable malignant neoplasm of Liver",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "hepatic cancer",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "hepatic neoplasm",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "malignant hepato-biliary neoplasm",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "malignant neoplasm of liver",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "malignant neoplasm of liver, primary",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "malignant tumor of liver",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "neoplasm of liver",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "non-resectable primary hepatic malignant neoplasm",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "primary liver cancer",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "primary malignant neoplasm of liver",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "resectable malignant neoplasm of the liver",
                            "description": ""
                        },
                        {
                            "id": "DOID:3571",
                            "resource": "Disease Ontology",
                            "url": "http://disease-ontology.org/term/DOID:3571",
                            "name": "malignant neoplasm of liver, not specified as primary or secondary",
                            "description": ""
                        }
                    ]
                }
            ]
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P0DN82",
                    "url": "https://www.uniprot.org/uniprot/P0DN82"
                }
            ],
            "common_name": "Human"
        }
    ],
    "gene": [
        {
            "name": "OR12D1",
            "url": "https://www.uniprot.org/uniprot/P0DN82",
            "locus": {
                "chromosome": "6",
                "start_pos": 29418905,
                "end_pos": 29414928,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSG00000251608",
                        "url": "https://www.ensembl.org/id/ENSG00000251608"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "cd15915",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15915",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "OR12D1",
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=OR12D1",
            "database": "GeneCards",
            "categories": [
                "Gene Annotation",
                "Organism-specific"
            ]
        },
        {
            "id": "26530",
            "url": "https://www.ncbi.nlm.nih.gov/gene/26530",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "8177",
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=8177",
            "database": "HGNC",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "IPR000276",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR000725",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017452",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NX_P0DN82",
            "url": "https://www.nextprot.org/entry/NX_P0DN82",
            "database": "neXtProt",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        },
        {
            "id": "PTHR26453",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR26453:SF683",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453:SF683",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13853",
            "url": "http://pfam.xfam.org/family/PF13853",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "P0DN82",
            "url": "https://pharos.nih.gov/targets/P0DN82",
            "database": "PHAROS",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "PR_P0DN82",
            "url": "http://purl.obolibrary.org/obo/PR_P0DN82",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001335137",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335137",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P0DN82",
            "url": "https://www.uniprot.org/uniprot/P0DN82",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P0DN82-1",
            "url": "https://www.uniprot.org/uniprot/P0DN82-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MLNTTSVTEFLLLGVTDIQELQPFLFVVFLTIYFISVAGNGAILMIVISDPRLHSPMYFFLGNLSCLDICYSSVTLPKMLQNFLSAHKAISFLGCISQLHFFHFLGSTEAMLLAVMAFDRFVAICKPLRYTVIMNPQLCTQMAITIWMIGFFHALLHSLMTSRLNFCGSNRIYHFFCDVKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITHLFFKTHSFSMLRKALSTCASHFMVVILLYAPVLFTYIHHASGTSMDQDRITAIMYTVVTPVLNPLIYTLRNKEVKGAFNRAMKRWLWPKEILKNSSEA",
        "length": 320,
        "header": "sp|P0DN82-1|O12D1_HUMAN Isoform 1 of Olfactory receptor 12D1  OS=Homo sapiens OX=9606 GN=OR12D1 PE=3 SV=2 CANONICAL=P0DN82-1"
    },
    "isoforms": [
        {
            "isoform_ac": "P0DN82-1",
            "url": "",
            "sequence": {
                "sequence": "MLNTTSVTEFLLLGVTDIQELQPFLFVVFLTIYFISVAGNGAILMIVISDPRLHSPMYFFLGNLSCLDICYSSVTLPKMLQNFLSAHKAISFLGCISQLHFFHFLGSTEAMLLAVMAFDRFVAICKPLRYTVIMNPQLCTQMAITIWMIGFFHALLHSLMTSRLNFCGSNRIYHFFCDVKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITHLFFKTHSFSMLRKALSTCASHFMVVILLYAPVLFTYIHHASGTSMDQDRITAIMYTVVTPVLNPLIYTLRNKEVKGAFNRAMKRWLWPKEILKNSSEA",
                "length": 320,
                "header": "sp|P0DN82-1|O12D1_HUMAN Isoform 1 of Olfactory receptor 12D1  OS=Homo sapiens OX=9606 GN=OR12D1 PE=3 SV=2 CANONICAL=P0DN82-1"
            },
            "locus": {
                "chromosome": "HSCHR6_MHC_DBB_CTG1",
                "start_pos": 683753,
                "end_pos": 682794,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000703726.1",
                        "url": "https://www.ensembl.org/id/ENST00000703726.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000515451.1",
                        "url": "https://www.ensembl.org/id/ENSP00000515451.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 3,
            "start_aa": "Asn",
            "end_pos": 3,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn3",
            "evidence": [
                {
                    "id": "P0DN82",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P0DN82#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Personal receptor repertoires: olfaction as a model.",
            "journal": "BMC Genomics",
            "date": "2012",
            "authors": "Olender Tsviya, Waszak Sebastian M, Viavant Maya, Khen Miriam, Ben-Asher Edna, Reyes Alejandro, Nativ Noam, Wysocki Charles J, Ge Dongliang, Lancet Doron",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P0DN82",
                    "url": "https://www.uniprot.org/uniprot/P0DN82"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22908908",
                    "url": "https://glygen.org/publication/PubMed/22908908"
                }
            ]
        }
    ],
    "pathway": [],
    "orthologs": [
        {
            "uniprot_canonical_ac": "B2RT33-1",
            "protein_name": "Olfactory receptor",
            "gene_name": "Or12d2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSNQTSVTEFLLLGVTDIQELNPILFVVFFTIYFVNITGNGAILMIVILDPRLHSPMYFFLGNLACLDICFSTVTLPKMLQNLLSTSKAISFLGCITQLHFFHFLGSTEAMLLPVMAFDRFVAICRPLHYSVIMNHQLCIHMTVTIWTLGFFHALLHSVMTSRLSFCGPNHVHHFFCDIKPLLDLACGNTELNLWLLNTVTGTIALTPFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVILLYVPVLFTYIRPASGSSLDQDRIIAIMYSVVTPALNPLIYTLRNKEVRSALNRKVRRWL",
                "length": 308
            },
            "evidence": [
                {
                    "id": "45916918",
                    "url": "http://www.informatics.jax.org/homology/45916918",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "D4ACU7-1",
            "protein_name": "Olfactory receptor",
            "gene_name": "Or12d13",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MSAPTSVSQGGKSVLLNQTLFTEFLLLGVTDIQELNPILFVTVLAMYFVNVFGNGAIMMIVILDPRLHSPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGSTEALLLTVMAFDRFVAICRPLHYPSIMNRQVCIQVAVSIWAIPFLHALVHSILTSRLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTLTGTVAIGLFFLTFLSYFYIISYLFLKTHSCSMLHKALSTCASHFMVVIIFYAPVLFIYINPDSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRIQL",
                "length": 322
            },
            "evidence": [
                {
                    "id": "45916893",
                    "url": "http://www.informatics.jax.org/homology/45916893",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "M0RDZ2-1",
            "protein_name": "Olfactory receptor",
            "gene_name": "Or12d14c",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MGVTDIQELNPILFLTFLVMYFVNVFGNGSILMIVILDPRLHSPMYFFLGNLACVDICFSTVTVPKMLENFFSTSKAISFLGCITQLYLFHFLGSTEALLLTVMAFDRFVAICRPLHYPSIMNSHVCIQLTVVIWAIPFIPALLHSILTSQLSFCGSNHVHHFFCDVKPLLELACGNTELNRWLLNTFTGTVAIALFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHVMVVIIFYAPVLFIYINPDSRSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRIQL",
                "length": 296
            },
            "evidence": [
                {
                    "id": "45916497",
                    "url": "http://www.informatics.jax.org/homology/45916497",
                    "database": "MGI"
                },
                {
                    "id": "45916495",
                    "url": "http://www.informatics.jax.org/homology/45916495",
                    "database": "MGI"
                },
                {
                    "id": "45916499",
                    "url": "http://www.informatics.jax.org/homology/45916499",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "P58182-1",
            "protein_name": "Olfactory receptor 12D2",
            "gene_name": "OR12D2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MLNTTSVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKPLRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVILFYAPVLFTYIHPALESFMDQDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL",
                "length": 307
            },
            "evidence": [
                {
                    "id": "45916893",
                    "url": "http://www.informatics.jax.org/homology/45916893",
                    "database": "MGI"
                },
                {
                    "id": "45916887",
                    "url": "http://www.informatics.jax.org/homology/45916887",
                    "database": "MGI"
                },
                {
                    "id": "45916497",
                    "url": "http://www.informatics.jax.org/homology/45916497",
                    "database": "MGI"
                },
                {
                    "id": "45916495",
                    "url": "http://www.informatics.jax.org/homology/45916495",
                    "database": "MGI"
                },
                {
                    "id": "45916499",
                    "url": "http://www.informatics.jax.org/homology/45916499",
                    "database": "MGI"
                },
                {
                    "id": "45916918",
                    "url": "http://www.informatics.jax.org/homology/45916918",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6MFW4-1",
            "protein_name": "Olfactory receptor",
            "gene_name": "Or12d2",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MSNQTSVTEFLLLGVTDIQELNPILFVIFFTIYFVNITGNGAILMIVILDPRLHSPMYFFLGNLACLDICFSTVTVPKMLENLLSTSKAISFLGCITQLHFFHFLGSTEALLLPVMAFDRFVAICRPLHYSVIMNRQLCSHMTVTIWIMGFLHALLHSVMTSRLSFCGPNHVHHFFCDIKPLLDLACGNTELNLWLLNTVTGTIALTPFFLTFLSYFYIITYLFLKTHSCSMLHKALSTCASHFMVVILLYVPVLFNYIRPASSSALDQERIIAIMYSVVTPALNPLIYTLRNKEVRNALNKKVRRWL",
                "length": 308
            },
            "evidence": [
                {
                    "id": "45916887",
                    "url": "http://www.informatics.jax.org/homology/45916887",
                    "database": "MGI"
                },
                {
                    "id": "45916918",
                    "url": "http://www.informatics.jax.org/homology/45916918",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q6MFW5-1",
            "protein_name": "Olfactory receptor",
            "gene_name": "Or12d2b",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MSNQTSVTEFLLLGVTDIQELNPILFVIFFTIYFVNITGNGAILMIVILDPRLHSPMYFFLGNLACLDICFSTVTVPKMLENLLSTSKAISFLGCITQLHFFHFLGSTEALLLPVMAFDRFVAICRPLHYSVIMNRQLCSHMTVTIWIIGFLHALLHSVMTSRLSFCGPNHVHHFFCDVKPLLDLACGNTELNLWLLNTVTGTIALTPFFLTFLSYFYIITYLLFKTRSCSMLHKALSTCASHFMVVCLFYAPVLFIYIRPSSGSSLDQERIIAIMYSVVTPALNPLIYTLRNKEVRSALNRKVRRWL",
                "length": 308
            },
            "evidence": [
                {
                    "id": "45916887",
                    "url": "http://www.informatics.jax.org/homology/45916887",
                    "database": "MGI"
                },
                {
                    "id": "45916918",
                    "url": "http://www.informatics.jax.org/homology/45916918",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q6MFW6-1",
            "protein_name": "Olfactory receptor",
            "gene_name": "Or12d2c",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MSNQTSVTEFLLLGVTDIQELNPILFVIFFTIYSVNITGNGAILMIVILDPRLHSPMYFFLGNLACLDICYSTVTVPKMLENLLSTSKAISFLGCITQLHFFHFLGSTEALLLPVMAFDRFVAICRPLHYSVIMNRQLCSHMTVTIWIMGFLHALLHSVMTSRLSFCGPNHVHHFFCDIKPLLELACGNTELNLWLLNTVTGTIALTPFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVILFYAPVLFTYICPTSGSAPDQDRIIAIMYSVVTPALNPLIYTLRNKEVRSALYRKVRKWL",
                "length": 308
            },
            "evidence": [
                {
                    "id": "45916887",
                    "url": "http://www.informatics.jax.org/homology/45916887",
                    "database": "MGI"
                },
                {
                    "id": "45916918",
                    "url": "http://www.informatics.jax.org/homology/45916918",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q920Y8-1",
            "protein_name": "Olfactory receptor",
            "gene_name": "Or12d13",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MLNQTSVTEFILLGVRDIQEPQPFLFAIFFTIYFVNITGNGAILMIVILDPRLHSPMYFFLGNLACLDISYSTVTVPKMLENLLSTNKAISLLGCITQLHFFHFLGTTESLLLAVMAFDRFVAICRPLHYSVIMNWQVCILMAVTIWTIAFLHALLHSVMTSRLSFCGLNHIHHFFCDVKPLLELACGNTELNLWLLNTVTGTIASVPFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVVLFYAPVLFTYIRPTSGSSLDQDRIIAIMYSVVTPALNPLIYTLRNKEVRSALNRKVRRCLLLEEI",
                "length": 313
            },
            "evidence": [
                {
                    "id": "45916893",
                    "url": "http://www.informatics.jax.org/homology/45916893",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q920Z0-1",
            "protein_name": "Olfactory receptor",
            "gene_name": "Or12d12",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSNQTSVTEFLLLGVTDIQELNPILFVIFFTIYFINITGNGAILMIVILDPRLHSPMYFFLGNLACLDISYSTVTVPKLLQNLLSTSKAISFLGCITQLHFFHFLGSTETMLLPVMAFDRFVAICRPLHYSVIMNHQLCIHMTVTIWTLGFFHALLHSVMTSRLSFCGPNHVHHFFCDIKPLLDLACGNTELNLWLLNTVTGTIALTSFFLIFLSYFYIITNLLLKTRSCSMLHKALSTCASHFMVVVLFYAPVLFTYIRPASGSSLDQDTIIAIMYSVVTPALNPLIYTLRNKEVRSALNRKVRRWL",
                "length": 308
            },
            "evidence": [
                {
                    "id": "45916887",
                    "url": "http://www.informatics.jax.org/homology/45916887",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "G protein-coupled receptor activity",
                        "id": "GO:0004930",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P0DN82",
                                "url": "https://www.uniprot.org/uniprot/P0DN82"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "olfactory receptor activity",
                        "id": "GO:0004984",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P0DN82",
                                "url": "https://www.uniprot.org/uniprot/P0DN82"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "odorant binding",
                        "id": "GO:0005549",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P0DN82",
                                "url": "https://www.uniprot.org/uniprot/P0DN82"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P0DN82",
                                "url": "https://www.uniprot.org/uniprot/P0DN82"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "detection of chemical stimulus involved in sensory perception of smell",
                        "id": "GO:0050911",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P0DN82",
                                "url": "https://www.uniprot.org/uniprot/P0DN82"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 316,
            "end_pos": 318,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 3,
            "end_pos": 5,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 63,
            "end_pos": 65,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [
            3
        ],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 316,
                "end_pos": 318
            },
            {
                "start_pos": 3,
                "end_pos": 5
            },
            {
                "start_pos": 63,
                "end_pos": 65
            }
        ]
    },
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 1
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
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        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
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                {
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                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
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                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
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                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 1
                },
                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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            "sort_fields": [
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        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
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                {
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                    "field": "n_linked_glycan_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
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                    "field": "total",
                    "count": 0
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                {
                    "field": "total_sites",
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